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ECG stress test induced atrial ischemia in a patient with old inferior myocardial infarction due to a distal coronary artery lesion

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Journal of Geriatric Cardiology 2017年第1期14卷 73-77页

作者： Andras Vereckei Gabor Katona Zsuzsanna Szelenyi Edit Takacs Pal Maurovich-Horvat David becker 3rd Department of Medicine Budapest Hungary MTA-SE Cardiovascular lmaging Research Group Heart and Vascular Center Budapest Hungary Center of Nuclear Medicine Semmelweis University Budapest Hungary

A 78-year-old man with a history of mitral valve prolapse underwent echocardiography during his cardiological check-up examination in 2011 in a symptom-free stage. Echocardiography revealed akinesis of the inferior septum and inferobasal free wall as a novel finding suggesting a distal right coronary artery （RCA） lesion （Figure 1）. The systolic left ventricular function was normal. Earlier echocardiographies did not show wall motion abnormalities.

关键词： Atrial infarction Atrial ischemia Electrocardiography

Species and endosymbiont diversity of Bemisia tabaci （Homoptera： Aleyrodidae） on vegetable crops in Senegal

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Insect Science 2015年第3期22卷 386-398页

作者： Delatte Helene Baudin Remy becker Nathalie Girard Anne-Laure Ramatoulaye Sidebe Traore Lett Jean-Michel Reynaud Bernard CIRAD UMR PVBMT F-97410 Saint-Pierre La Reunion France Museum National d'Histoire Naturelle Institut de Systematique Evolution Biodiversite ISYEB UMR 7205 CNRS UPMC EPHE 75005 Paris France TECHNISEM Zone d'activite Anjou Actiparc de Jumelles 49160 Longue-Jumelles France

Bemisia tabaci-transmitted geminiviruses are one of the major threats on cassava and vegetable crops in Africa. However, to date, few studies are available on the diversity orB. tabaci and their associated endosymbionts in Africa. More than 28 species have been described in the complex ofB. tabaci cryptic species; among them, 2 are invasive pests worldwide： MED and MEAM1. In order to assess the species diversity orB. tabaci in vegetable crops in Senegal, several samplings in different localities, hosts and seasons were collected and analyzed with nuclear （microsatellite） and mitochondrial （COI） markers. The bacterial endosymbiont community was also studied for each sample. Two species were detected： MED Q1 and MEAM1 B. Patterns of MED Q1 （dominance on most of the samples and sites, highest nuclear and mitochondrial diversity and broader secondary endosymbiont community： Hamiltonella, Cardinium, Wolbachia and Rickettsia）, point toward a predominant resident begomovirus vector group for MED Q 1 on market gardening crops. Furthermore, the lower prevalence of the second species MEAM1 B, its lower nuclear and mitochondrial diversity and a narrower secondary endosymbiont community （Hamiltonella/Rickettsia）, indicate that this genetic group is exotic and results from a recent invasion in this area.

关键词： begomovirus vectors endosymbionts diversity MED and MEAM 1 species microsatellites mtCOI phylogeny whitefly

A comparison of outcomes between laparoscopic and robotic appendectomy among ACS-NSQIP hospitals

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Laparoscopic, Endoscopic and Robotic Surgery 2023年第2期6卷 39-42页

作者： Timothy becker Genaro DeLeon Varun Rao Kevin Y.Pei Indiana University School of Medicine 340 W 10th StIndianapolisIN 46202USA Parkview Health General Surgery Graduate Medical Education 2200 Randallia DrFort WayneIN 46805USA

Objective:Robotic general surgery remains controversial,with some employing the technology for common laparoscopic procedures such as *** few studies have compared robotic appendectomy(RA)to existing techniques,partly due to the relative scarcity of *** purpose of this study was to compare outcomes for RA versus laparoscopic appendectomy(LA).Methods:This retrospective cohort study evaluated procedural specific databases of the American Col-lege of Surgeons National Surgical Quality Improvement Program(ACS-NSQIP)for appendectomy be-tween January 2016 and December 2019 and included all available cases at the time of analysis(June 2021).Demographic and surgical outcomes including composite 30-day complications,specific com-plications,and length of operation were analyzed using a univariate ***:In total,there were 52,559 appendectomies in the NSQIP database between 2016 and *** was restricted to those who underwent minimally invasive *** total,49,850 patients were included in the *** those,49,800 patients underwent LA,and 50 patients underwent *** who underwent RA were older(35.8±4.5 y vs.23.0±0.2 y,p0.90)between RA and LA *** had a longer median operation time(71.0 min vs.46.0 min,p<0.01)but a shorter postoperative stay(0.7 d vs.1.3 d,p<0.01).There was no difference in the frequency of readmission likely related to procedure(4.0%vs.3.0%,p=0.88)or complications(18.0%vs.23.8%,p=0.88);however,RA was associated with increased 30-day mortality(2.0%vs.<0.1%,p<0.01)compared to ***:Our results demonstrated that LA and RA had a similar frequency and profile of *** procedures took longer but resulted in shorter postoperative *** study revealed that RA constituted a mere 0.1%of all cases,with only 50% showing pathology consistent with appendiciti

关键词： Robotics Appendectomy General surgery NSQIP Postoperative complication

Variation-aware fault modeling

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Science China(Information Sciences) 2011年第9期54卷 1813-1826页

作者： HOPSCH Fabian becker Bernd HELLEBRAND Sybille POLIAN Ilia STRAUBE Bernd VERMEIREN Wolfgang WUNDERLICH Hans-Joachim Fraunhofer IIS/EAS University of Freiburg University of Paderborn University of Passau University of Stuttgart

To achieve a high product quality for nano-scale systems,both realistic defect mechanisms and process variations must be taken into *** existing approaches for variation-aware digital testing either restrict themselves to special classes of defects or assume given probability distributions to model variabilities,the proposed approach combines defect-oriented testing with statistical library *** uses Monte Carlo simulations at electrical level to extract delay distributions of cells in the presence of defects and for the defect-free *** allows distinguishing the effects of process variations on the cell delay from defect-induced cell delays under process *** provide a suitable interface for test algorithms at higher levels of abstraction,the distributions are represented as histograms and stored in a histogram data base (HDB).Thus,the computationally expensive defect analysis needs to be performed only once as a preprocessing step for library characterization,and statistical test algorithms do not require any low level information beyond the *** generation of the HDB is demonstrated for primitive cells in 45 nm technology.

关键词： process variations test methods statistical test histogram data base

The potential information in the temperature difference between shadow and sunlit of surfaces and a new way of retrieving the soil moisture

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Science China Earth Sciences 2001年第2期44卷 112-123页

作者：张仁华苏红波李召良孙晓敏唐新斋 F.becker Institute of Geography Sciences and Natural Resources Research Chinese Academy of Sciences Beijing China Laboratoire des Sciences de I’Image De I’Informatique et de la Teledetection Illkirch France

The thermal inertia and plant water stress index are oftenadopted to estimate soil moisture available for crops or plants. However, it is not very easy to obtain two temporal temperatures for thermal inertia model and air temperature for the plant water stress mode. Shadows of ground objects are often referred to noise on visible and near infrared remote sensing. But the difference of temperature between shadows and sunlit contains rich information concerning with heat-water status for soil. This paper presented a new way to excavate just by temperature difference usually between shadow and sunlit surface. Experiments validated the ideal. We can adopt thermal camera to measure the differences in the field measurements. However, we must use inversion based on multianglar thermal infrared remote sensing data in airborne and spaceborne. An inverting model was also presented by using Monte-Carlo and the least square method. Results show that this way is feasible.

关键词： shadow sunlit soil water crop water stress index multi-angular remote sensing thermal geometric model

时间相关单光子计数记录快速荧光寿命图像(英文)

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深圳大学学报（理工版） 2008年第3期25卷 238-243页

作者： Bertram SU Vicky KATSOULIDOU Wolfgang becker becker&Hickl公司 Nahmitzer Damm 30德国柏林D-12277

基于时间相关单光子计数(TCSPC)的荧光寿命成像(FLIM)的获取时间取决于成像的图像尺寸、样品寿命的精度及样品计数率.对于高密度荧光团样品,如染色组织或植物细胞,当前可用的样品计数率与TCSPC荧光寿命成像技术最高的计数率接近.该文描... 详细信息

基于时间相关单光子计数(TCSPC)的荧光寿命成像(FLIM)的获取时间取决于成像的图像尺寸、样品寿命的精度及样品计数率.对于高密度荧光团样品,如染色组织或植物细胞,当前可用的样品计数率与TCSPC荧光寿命成像技术最高的计数率接近.该文描述了在高计数率下TCSPC性能,并估计计数损失及堆积效应.结果表明,整个体系的寿命误差比预料的要小.因此, TCSPC FLIM可在获取时间低于1s的情况下记录寿命图像.为增加FLIM时间序列记录,利用存储交换技术,在采集下一个光子期间读取正在记录的数据,使用两个平行TCSPC模块,可以每秒两幅图像记录荧光寿命时间序列.该技术可应用于活体植物组织叶绿素的瞬态测量.

关键词：荧光寿命成像技术时间相关单光子计数叶绿素瞬态测量

Transcriptome landscape of the early Brassica napus seed

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Journal of Integrative Plant Biology 2019年第5期61卷 639-650页

作者： Dylan J.Ziegler Deirdre Khan Jenna L.Kalichuk Michael G.becker Mark F.Belmonte University of Manitoba

Brassica napus L.(canola) is one of the world’s most economically important oilseeds. Despite our growing knowledge of Brassica genetics, we still know little about the genes and gene regulatory networks underlying early seed development. In this work, we use laser microdissection coupled with RNA sequencing to profile gene activity of both the maternal and filial subregions of the globular seed. We find subregions of the chalazal end including the chalazal endosperm, chalazal proliferating tissue, and chalazal seed coat, have unique transcriptome profiles associated with hormone biosynthesis and polysaccharide metabolism. We confirm that the chalazal seed coat is uniquely enriched for sucrose biosynthesis and transport, and that the chalazal endosperm may function as an important regulator of the maternal region through brassinosteroid synthesis. The chalazal proliferating tissue,a poorly understood subregion, was specifically enriched in transcripts associated with megasporogenesis and trehalose biosynthesis, suggesting this ephemeral structure plays an important role in both sporophytic development and carbon nutrient balance, respectively. Finally, compartmentalization of transcription factors and their regulatory circuits has uncovered previously unknown roles for the chalazal pole in early seed development.

关键词： Brassica napus L.(canola) understood subregion

Neurocognition in stimulant addiction: reply to Robbins (2021)

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Psychoradiology 2021年第2期1卷 91-93页

作者： Benjamin becker University of Electronic Science and Technology of China School of Life Science and TechnologyChina

On behalf of all authors who contributed to our recent article describing the results from a prospective longitudinal study demonstrating amphetaminetype stimulant-(ATS-)induced reductions in putamen volume and associated cognitive decline in moderate users of these drugs(Kendrick et al.,2021),I thank Professor Trevor Robbins for the flanking *** commentary in the current issue of Psychoradiology(Robbins,2021)sets our findings into the context of recent developments in the field of addiction research and I would like to take the opportunity to further elaborate on progress as well as challenges in neuroimaging of addiction.

关键词： Robbins behalf addiction

Mast cells as rapid innate sensors of cytomegalovirus by TLR3/TRIF signaling-dependent and -independent mechanisms

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Cellular & Molecular Immunology 2015年第2期12卷 192-201页

作者： Marc becker Niels AW Lemmermann Stefan Ebert Pamela Baars Angelique Renzaho Jurgen Podlech Michael Stassen Matthias J Reddehase Institute for Immunology Research Center for Immunotherapy (FZI) at the University Medical Center of the Johannes Gutenberg University Mainz Germany Institute for Virology Research Center for Immunotherapy (FZI) at the University Medical Center of the Johannes Gutenberg University Mainz Germany These authors contributed equally to this work Co-senior authors

The succinct metaphor,‘the immune system＇s loaded gun＇, has been used to describe the role of mast cells （MCs） due to their storage of a wide range of potent pro-inflammatory and antimicrobial mediators in secretory granules that can be released almost instantly on demand to fight invaders. Located at host-environment boundaries and equipped with an arsenal of pattern recognition receptors, MCs are destined to be rapid innate sensors of pathogens penetrating endothelial and epithelial surfaces. Although the importance of MCs in antimicrobial and antiparasitic defense has long been appreciated, their role in raising the alarm against viral infections has been noted only recently. Work on cytomegalovirus （CMV） infection in the murine model has revealed MCs as players in a novel cross-talk axis between innate and adaptive immune surveillance of CMV, in that infection of MCs, which is associated with MC degranulation and release of the chemokine CCL5, enhances the recruitment of protective CD8 T cells to extravascular sites of virus replication, specifically to lung interstitium and alveolar epithelium. Here, we have expanded on these studies by investigating the conditions for MC activation and the consequent degranulation in response to host infection. Surprisingly, the data revealed two temporally and mechanistically distinct waves of MC activation： an almost instant indirect activation that depended on TLR3/TRIF signaling and delayed activation by direct infection of MCs that did not involve TLR3/rRIF signaling. Cell type-specific Cre-recombination that yielded eGFP-expressing reporter virus selectively originating from MCs identified MC as a new in vivo, first-hit target cell of productive murine CMV infection.

关键词： cytomegalovirus innate immunity mast cells mast cell-specific Cre-recombination TLR3FrRIF-signaling