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Cardiac arrest, stony heart, and cardiopulmonary resuscitation: An updated revisit

World Journal of Cardiology 2024年第3期16卷 126-136页

作者： Ayman el-Menyar Bianca M Wahlen Department of Trauma and Vascular Surgery Clinical ResearchHamad Medical CorporationDoha 3050Qatar Department of Clinical Medicine Weill Cornell Medical CollegeDoha 24144Qatar Department of Anesthesiology Hamad Medical CorporationDoha 3050Qatar

The post-resuscitation period is recognized as the main predictor of cardiopul-monary resuscitation(CPR)*** first description of post-resuscitation syndrome and stony heart was published over 50 years *** manifestations may include but are not limited to,persistent precipitating pathology,systemic ischemia/reperfusion response,post-cardiac arrest brain injury,and finally,post-cardiac arrest myocardial dysfunction(PAMD)after successful *** do some patients initially survive successful resuscitation,and others do not?Also,why does the myocardium response vary after resuscitation?These ques-tions have kept scientists busy for several decades since the first successful resuscitation was *** modifying the conventional modalities of resu-scitation together with new promising agents,rescuers will be able to salvage the jeopardized post-resuscitation myocardium and prevent its progression to a dismal,stony *** awareness and staff education are crucial for shortening the resuscitation time and improving short-and long-term *** of these components before and early after the restoration of circulation will enhance the resuscitation *** review extensively addresses the underlying pathophysiology,management,and outcomes of post-resuscitation *** pattern,management,and outcome of PAMD and post-cardiac arrest shock are different based on many factors,including in-hospital cardiac arrest vs out-of-hospital cardiac arrest(OHCA),witnessed vs unwitnessed cardiac arrest,the underlying cause of arrest,the duration,and protocol used for *** restoring spontaneous circulation is a vital sign,it should not be the end of the game or lone primary outcome;it calls for better understanding and aggressive multi-disciplinary interventions and *** development of stony heart post-CPR and OHCA remain the main challenges in emergency and critical care medicine.

关键词： Cardiac arrest Out-of-hospital cardiac arrest In-hospital cardiac arrest Post-resuscitation Myocardial dysfunction Cardiopulmonary resuscitation Stony heart

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Beyond p-y method:A review of artificial intelligence approaches for predicting lateral capacity of drilled shafts in clayey soils

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Journal of Rock Mechanics and Geotechnical Engineering 2024年第9期16卷 3812-3840页

作者： M.E.Al-Atroush A.E.Aboelela Ezz el-Din Hemdan Civil and Environmental Engineering Program Engineering Management DepartmentCollege of EngineeringPrince Sultan UniversityRiyadhSaudi Arabia Department of Structural Engineering Faculty of EngineeringAin Shams UniversityCairoEgypt Structure and Materials Research Lab Prince Sultan UniversityRiyadhSaudi Arabia Computer Science and Engineering Department Faculty of Electronic EngineeringMenoufia UniversityMenoufiaEgypt

In 2023,pivotal advancements in artificial intelligence(AI)have significantly *** that in mind,traditional methodologies,notably the p-y approach,have struggled to accurately model the complex,nonlinear soil-structure interactions of laterally loaded large-diameter drilled *** study undertakes a rigorous evaluation of machine learning(ML)and deep learning(DL)techniques,offering a comprehensive review of their application in addressing this geotechnical challenge.A thorough review and comparative analysis have been carried out to investigate various AI models such as artificial neural networks(ANNs),relevance vector machines(RVMs),and least squares support vector machines(LSSVMs).It was found that despite ML approaches outperforming classic methods in predicting the lateral behavior of piles,their‘black box'nature and reliance only on a data-driven approach made their results showcase statistical robustness rather than clear geotechnical insights,a fact underscored by the mathematical equations derived from these ***,the research identified a gap in the availability of drilled shaft datasets,limiting the extendibility of current findings to large-diameter *** extensive dataset,compiled from a series of lateral loading tests on free-head drilled shaft with varying properties and geometries,was introduced to bridge this *** paper concluded with a direction for future research,proposes the integration of physics-informed neural networks(PINNs),combining data-driven models with fundamental geotechnical principles to improve both the interpretability and predictive accuracy of AI applications in geotechnical engineering,marking a novel contribution to the field.

关键词： Laterally loaded drilled shaft load transfer and failure mechanisms Physics-informed neural networks(PINNs) P-y curves Artificial intelligence(AI) Dataset

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Feasibility and outcomes of robotic partial pancreatoduodenectomy

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Hepatobiliary Surgery and Nutrition 2024年第4期13卷 669-671页

作者： Antoine Rouault yasmina Richa Mehdi el Amrani Department of Digestive Surgery and Transplantation Lille University HospitalLilleFrance School of Medicine University College CorkCorkIreland

We read with great interest the randomized controlled trial(RCT)by Klotz et al.(1),which is the first to compare the 90-day postoperative morbidity of minimally invasive robotic partial pancreatoduodenectomy(RPD)to that of the current gold standard,open partial pancreatoduodenectomy(OPD)for all *** study arises in the context of a significant increase in surgical indications for robotic-assisted *** absence of clear recommendations or high-level evidence on RPDs prompted Klotz et *** conduct this phase 2b RCT to directly compare RPD to OPD.

关键词： Robotic minimally invasive pancreatoduodenectomy(PD)

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Gastroesophageal reflux after per-oral endoscopic myotomy:Management literature

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World Journal of Gastroenterology 2024年第23期30卷 2947-2953页

作者： Ahmed Tawheed Ibrahim Halil Bahcecioglu Mehmet yalniz Mohamed el-Kassas Department of Endemic Medicine Faculty of MedicineHelwan UniversityCairo 11795Egypt Department of Gastroenterology Faculty of MedicineFirat UniversityElazig 23119Türkiye Liver Disease Research Center College of MedicineKing Saud UniversityRiyadh 7805Saudi Arabia

In this editorial,we respond to a review article by Nabi et al,in which the authors discussed gastroesophageal reflux(GER)following peroral endoscopic myotomy(POEM).POEM is presently the primary therapeutic option for achalasia,which is both safe and effective.A few adverse effects were documented after POEM,including *** diagnostic criteria were not clear enough because approximately 60%of patients have a long acid exposure time,while only 10%experience reflux *** predictors of high disease incidence have been identified,including old age,female sex,obesity,and a baseline lower esophageal sphincter pressure of less than 45 *** technical steps during the procedure,such as a lengthy or full-thickness myotomy,may further enhance the *** pump inhibitors are currently the first line of *** voices are increasingly advocating for the routine combining of POEM with an endoscopic fundoplication method,such as peroral endoscopic fundoplication or transoral incisionless ***,more research is necessary to determine the safety and effectiveness of these procedures in the long term for patients who have undergone them.

关键词： Achalasia Per-oral endoscopic myotomy Gastroesophageal reflux disease Transoral incisionless fundoplication Peroral endoscopic fundoplication

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Multi-task learning for PBFT optimisation in permissioned blockchains

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Blockchain(Research and Applications) 2024年第3期5卷 89-105页

作者： Kenza Riahi Mohamed-el-Amine Brahmia Abdelhafid Abouaissa Lhassane Idoumghar CESI LINEACT UR 7527StrasbourgFrance IRIMAS University of Haute AlsaceUR 7499MulhouseFrance

Finance,supply chains,healthcare,and energy have an increasing demand for secure transactions and data *** blockchains fulfilled this need thanks to the consensus protocol that ensures that participants agree on a common *** of the most widely used protocols in private blockchains is the Practical Byzantine Fault Tolerance(PBFT),which tolerates up to one-third of Byzantine nodes,performs within partially synchronous systems,and has superior throughput compared to other *** has,however,an important bandwidth consumption:2N(N-1)messages are exchanged in a system composed of𝑁nodes to validate only one *** is possible to reduce the number of consensus participants by restricting the validation process to nodes that have demonstrated high levels of security,rapidity,and *** this paper,we propose the first database that traces the behavior of nodes within a system that performs PBFT *** reflects their level of security,rapidity,and availability throughout the *** first investigate different Single-Task Learning(STL)techniques to classify the nodes within our ***,using Multi-Task Learning(MTL)techniques,the results are much more interesting,with classification accuracies over 98%.Integrating node classification as a preliminary step to the PBFT protocol optimizes the *** the best cases,it is able to reduce the latency by up to 94%and the communication traffic by up to 99%.

关键词： Blockchain PBFT Dataset Nodes classification Single-task learning Multi-task learning

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Distinct electrical and Mechanical Responses of a Cu-10Fe Composite Prepared by Hot-Pressed Sintering and Post Treatment

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Acta Metallurgica Sinica(English Letters) 2024年第2期37卷 255-265页

作者： X.y.yue S.y.Peng X.Zhang C.N.He y.Z.Tian Key Laboratory for Anisotropy and Texture of Materials(Ministry of Education) School of Materials Science and EngineeringNortheastern UniversityShenyang110819China School of Materials Science and Engineering and Tianjin Key Laboratory of Composite and Functional Materials Tianjin UniversityTianjin300350China Research Centre for Metallic Wires Northeastern UniversityShenyang110819China

A Cu-10wt%Fe composite was prepared through hot-pressed sintering,and the material was subsequently solution *** hot-pressed sintered and solution treated materials were rolled and *** precipitation behavior and performance changes were systematically studied by using scanning electron microscopy and transmission electron *** contrast to the hot-pressed sintered specimen,the solution treatment significantly affects the thermal stability and properties of the Cu-10wt%Fe *** Cu-10wt%Fe composite was prepared after solid solution,cold rolling and aging at 773 K for 1 h,and it obtained excellent tensile strength of 494 MPa,uniform elongation of 16.3%,electrical conductivity of 51.1%IACS and softening temperature of 838 *** for the distinct difference in thermal stability and properties between hot-pressed sintered and solution treated specimens were *** findings provide a theoretical basis for designing high-performance Cu-based in-situ composites by post treatment.

关键词： Cu-Fe composite Hot-pressed sintering Thermal stability Strength electrical conductivity

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Bi-revealed utilities in a defaultable universe: A new point of view on consumption

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Probability, Uncertainty and Quantitative Risk 2024年第1期9卷 13-34页

作者： Nicole el Karoui Caroline Hillairet Mohamed Mrad LPSM UMR CNRS 6632Sorbonne Université4 Place Jussieu75005 ParisFrance CREST UMR CNRS 9194Ensae Paris5 Avenue Henry Le Chatelier91120 PalaiseauFrance LAGA UMR CNRS 7539UniversitéSorbonne Paris-Nord99 Avenue Jean Baptiste Clement93430 VilletaneuseFrance

This paper investigates the inverse problem of bi-revealed utilities in a defaultable universe,defined as a standard universe(represented by a filtration F)perturbed by an exogenous defaultable time τ.We assume that the standard universe does not take into account the possibility of the default,thus τ adds an additional source of *** defaultable universe is represented by the filtration G up to time τ(τ included),where G stands for the progressive enlargement of F by *** basic assumption in force is that τ avoids F-stopping *** bi-revealed problem consists in recovering a consistent dynamic utility from the observable characteristic of an *** general results on bi-revealed utilities,first given in a general and abstract framework,are translated in the defaultable G-universe and then are interpreted in the *** decomposition of G-adapted processes X^(G) provides an interpretation of a Gcharacteristic X^(G)_(τ) stopped at τ as a reserve *** to the characterization of G-martingales stopped at τ in terms of F-martingales,we establish a correspondence between G-bi-revealed utilities from characteristic and F-bi-revealed pair of utilities from characteristic and *** a financial framework,characteristic can be interpreted as wealth and reserves as *** result sheds a new light on the consumption in utility criterion:the consumption process can be interpreted as a certain quantity of wealth,or reserves,that are accumulated for the financing of losses at the default time.

关键词： Bi-revealed utilities Defaultable euniverse Enlargement offiltration Preference criteria of wealth and consumption

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Optimization of Cooperative RelayingMolecular Communications for Nanomedical Applications

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Computer Modeling in Engineering & Sciences 2024年第2期138卷 1259-1275页

作者： Eman S.Attia Ashraf A.M.Khalaf Fathi E.Abd el-Samie Saied M.Abd el-atty Konstantinos A.Lizos Osama Alfarraj Heba M.el-Hoseny Department of electrical Engineering Faculty of EngineeringMinia UniversityMinia61111Egypt Department of electronics and electrical Communications Engineering Faculty of Electronic EngineeringMenoufia UniversityMenouf32952Egypt Department of Informatics Faculty of Mathematics and Natural SciencesUniversity of Oslo(UiO)OsloNorway Computer Science Department Community CollegeKing Saud UniversityRiyadh11437Saudi Arabia Department of Computer science The Higher Future Institute for Specialized Technological StudiesEl ShoroukEgypt

Recently,nano-systems based on molecular communications via diffusion(MCvD)have been implemented in a variety of nanomedical applications,most notably in targeted drug delivery system(TDDS)***,because the MCvD is unreliable and there exists molecular noise and inter symbol interference(ISI),cooperative nano-relays can acquire the reliability for drug delivery to targeted diseased cells,especially if the separation distance between the nano transmitter and nano receiver is *** this work,we propose an approach for optimizing the performance of the nano system using cooperative molecular communications with a nano relay scheme,while accounting for blood flow effects in terms of drift *** fractions of the molecular drug that should be allocated to the nano transmitter and nano relay positioning are computed using a collaborative optimization problem solved by theModified Central Force Optimization(MCFO)*** the previous work,the probability of bit error is expressed in a closed-form *** is used as an objective function to determine the optimal velocity of the drug molecules and the detection threshold at the nano *** simulation results show that the probability of bit error can be dramatically reduced by optimizing the drift velocity,detection threshold,location of the nano-relay in the proposed nano system,and molecular drug budget.

关键词： Nanomedical system molecular communication cooperative relay optimization

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Effects of high glucose and severe hypoxia on the biological behavior of mesenchymal stem cells at various passages

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World Journal of Stem Cells 2024年第4期16卷 434-443页

作者： Fatimah Almahasneh Ejlal Abu-el-Rub Ramada R Khasawneh Rawan Almazari Department of Basic Medical Sciences Faculty of MedicineYarmouk UniversityIrbid 21163Jordan

BACKGROUND Mesenchymal stem cells(MSCs)have been extensively studied for therapeutic potential,due to their regenerative and immunomodulatory *** passage and stress factors may affect the biological characteristics of MSCs,but the details of these effects have not been recognized *** To investigate the effects of stress factors(high glucose and severe hypoxia)on the biological characteristics of MSCs at different passages,in order to optimize the therapeutic applications of *** In this study,we investigated the impact of two stress conditions;severe hypoxia and high glucose on human adipose-tissue derived MSCs(hAD-MSCs)at passages 6(P6),P8,and ***,senescence and apoptosis were evaluated measuring WST-1,senescence-associated beta-galactosidase,and annexin V,*** Cells at P6 showed decreased proliferation and increased apoptosis under conditions of high glucose and hypoxia compared to control,while the extent of senescence did not change significantly under stress *** P8 hAD-MSCs cultured in stress conditions had a significant decrease in proliferation and apoptosis and a significant increase in senescence compared to counterpart cells at *** cultured in high glucose at P10 had lower proliferation and higher senescence than their counterparts in the previous passage,while no change in apoptosis was *** the other hand,MSCs cultured under hypoxia showed decreased senescence,increased apoptosis and no significant change in proliferation when compared to the same conditions at *** These results indicate that stress factors had distinct effects on the biological processes of MSCs at different passages,and suggest that senescence may be a protective mechanism for MSCs to survive under stress conditions at higher passage numbers.

关键词： Mesenchymal stem cells High glucose Hypoxia Stressful microenvironment Serial passage Senescence Apoptosis

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Assessment of thermal comfort in the traditional and contemporary houses in Byblos:A comparative study

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Energy and Built Environment 2024年第6期5卷 933-945页

作者： Amal Chkeir youcef Bouzidi Zoubayre el Akili Mahmoud Charafeddine Zeinab Kashmar Interdisciplinary Research on Society-Technology-Environment Interactions(Insyte) University of Technology of TroyesFrance ATEC Old Street of Saida ChiyahBeyrouthLebanon Line&Design Pty Ltd Australia

This paper presents a comparative study on the thermal comfort of traditional and contemporary houses in Byblos,*** climate change affecting indoor environments and potentially leading to increased energy consumption,achieving optimal thermal comfort is a crucial issue for building *** study analyzes several environmental parameters and conducts an occupancy survey to assess thermal comfort in both types of *** questionnaire used in the survey consists of 46 questions divided into three parts:“Who are you?”,“The environment of your house?”,and“Architectural characteristics of the house.”The results show that traditional houses perform better than contemporary ones in terms of thermal comfort,due to their use of natural and passive ***,both types of houses have room for improvement in terms of energy *** study provides insights into potential solutions for improving indoor thermal comfort while reducing energy consumption in traditional and contemporary houses.

关键词： Thermal comfort Building Indoor environment Traditional houses Contemporary houses

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