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丙型肝炎复发患者肝移植后的纤维化进展

世界核心医学期刊文摘（胃肠病学分册） 2005年第4期1卷 60-61页

作者： neumann u.P. Berg T. Bahra M. 姜志茹

Aim of our study was to analyze fibrosis progression after liver transplantation (OLT) in hepatitis C virus (HCV)-infected patients based on protocol liver biopsies and to identify risk factors, which may play a role in the development of severe fibrosis stages. One hundred and eighty-three liver graft recipients who had a histological follow-up eva.u.tion of 1 year after OLT were analyzed. Overall 1039 protocol liver biopsies were performed after 1-, 3-, 5-, 7-and 10 years and staged according to the Scheuer score. The fibrosis progression rate was not linear. The fibrosis scores were 1.2 after one, 1.7 after three, 1.9 after five, 2.1 after 7 and 2.2 after 10 years. The 39 recipients with fibrosis stages 3 or 4 in the 1-year biopsy had a significantly reduced survival rate, while fibrosis stage 0-2 indicated excellent survival. Independent risk factors for progression of fibrosis at 1 year were HCV genotype 1 and 4 (P=0.01) and donor age > 33 years (P=0.01), whereas risk factors for development of cirrhosis (30/183 recipients (16%)) were donor age (P=0.002) and multiple steroid pulses (P=0.05). These data provide information on the course of recurrent hepatitis C and may be helpful to individualize the treatment of transplanted patients.

关键词：肝移植丙型肝炎纤维化进展肝活检患者生存时间

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可控气体渗碳时减少气体消耗量的基本途径

国外化学热处理 1981年第5期 43-53页

作者： u. Wyss R. Hoffman F. neumann 杜赓林蔡慰望

1.关于替代发生炉吸热式气体的概况 1.1 引言 30多年前,人们就已经知道了将吸热式载气法用于钢的渗碳或保护气氛加热。这一方法已成为最广泛采用的气体渗碳法。当前,特别是由于控制技术的发展,业已证实这一方法是可靠的。在采用这种方... 详细信息

1.关于替代发生炉吸热式气体的概况 1.1 引言 30多年前,人们就已经知道了将吸热式载气法用于钢的渗碳或保护气氛加热。这一方法已成为最广泛采用的气体渗碳法。当前,特别是由于控制技术的发展,业已证实这一方法是可靠的。在采用这种方法之前,人们已经使用了粉末渗碳法或者气体渗碳时

关键词：碳势控制 CO 裂解反应气体渗碳渗剂渗碳剂消耗量

STM and Raman Spectroscopic Study of Graphite Irradiated by Heavy Ions

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IMP & HIRFL Annual Report 2002年 52-53页

作者： C.Trautmann,R.neumann,C.Müller Gesellschaft fur Schwerionenforschung(GSI) Planckstr.1 64291 Darmstadt Germany. Gesellschaft fur Schwerionenforschung(GSI) Planckstr.1 64291 Darmstadt Germany. Gesellschaft fur Schwerionenforschung(GSI) Planckstr.1 64291 Darmstadt Germany.

Freshly-cleaved HOPG crystals were irradiated with Ni, Zn, Xe and u ions of specific energy 11.4 MeV/u at the linear accelerator uNILAC and with Ne, Cr, Zn, Xe ions (1.4 MeV/u) at the high-charge injector HLI, both facilities are in operation at GSI, Darmstadt. The irradiation with Fe ions was performed at HIRFL (22 MeV/u) of IMP, Lanzhou. All irradiations were performed at room tempera.u.e and under beam incidence normal

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术前检测患者血液中总蛋白、白蛋白与白细胞介素-1受体拮抗剂作为切口疝修补术后是否出现血清肿的预测指标

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中华疝和腹壁外科杂志：电子版 2012年第2期6卷 77-79页

作者： Klink CD Binnebosel M Lucas AH Schachtrupp A Grommes J Conze J Klinge u neumann u Junge K 宗振（译）陈双（校）不详中山大学附属孙逸仙纪念医院胃肠胰腺外科华南疝外科治疗培训中心广州510120

患者切口疝修补术后出现血清肿是非常常见的,约占20%～30%,其中10%的患者渗液量超过50ml。出现血清肿并不一定出现并发症,但血清肿患者术后容易出现疼痛不适,尤其是补片感染导致修补手术失败,切口疝复发。对某些患者及时使用细针抽液,... 详细信息

患者切口疝修补术后出现血清肿是非常常见的,约占20%～30%,其中10%的患者渗液量超过50ml。出现血清肿并不一定出现并发症,但血清肿患者术后容易出现疼痛不适,尤其是补片感染导致修补手术失败,切口疝复发。对某些患者及时使用细针抽液,甚至是手术治疗都是必要的。

关键词：白细胞介素-1受体拮抗剂修补术后血清肿切口疝患者术前检测预测指标总蛋白

STM and Raman Spectroscopic Study of Graphite Irradiated by Heavy Ions

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近代物理研究所和兰州重离子加速器实验室年报：英文版 2002年第1期 52-53页

作者： LiuJie HouMingdong C.Trautmann R.neumann C.Mfiller WangZhiguang SunYoumei JinYunfan LiuHongwen GaoHongjun 不详 GesellschaftfuerSchwerionenforschung（GSI） Planckstr.164291DarmstadtGermany InstituteofPhysics theChineseAcademyofSciences（C.kS）BeijingChina.

关键词：石墨重离子辐照拉曼光谱重离子核物理扫描隧道显微镜分析 STM 晶体表面结构研究

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测量纱线长度和速度的非接触式传感器

国际纺织导报 2006年第12期34卷 59-60页

作者： B. Mrozik G. Hoffmann C. Cherif u. neumann J. Posvic 张琳（译）李毓陵（校）德累斯顿工业大学纺织与服装技术研究所德国诺伊曼电气技术公司德国不详

介绍了一种新型测量纱线长度和速度的传感器,该传感器的功能已由实验证实。其原理是利用纱线上的静电荷进行非接触测量。所研制的传感器能用于测量各种原料纱线的长度和速度。在实际应用中,这种传感器可用于一些尚无经济实用解决方案的... 详细信息

介绍了一种新型测量纱线长度和速度的传感器,该传感器的功能已由实验证实。其原理是利用纱线上的静电荷进行非接触测量。所研制的传感器能用于测量各种原料纱线的长度和速度。在实际应用中,这种传感器可用于一些尚无经济实用解决方案的场合。

关键词：纱线长度速度测量传感器

波罗的海西南Achterwasser泻湖富黄铁矿沉积物中痕量元素成岩作用

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海洋地质 2015年第4期31卷 59-75页

作者： Florian Scholz Thomas neumann 甘华阳不详广州海洋地质调查局海洋环境地质与工程地质调查所

本文研究了黄铁矿形成背景下波罗的海无潮的Oder河口中一个浅泻湖Achterwasser缺氧沉积物中痕量元素（V、Cr、Co、Cu、Zn、As、Cd、Ba.u.的早期成岩作用。溶解的主要氧化还原参数呈现出一个双层分布：具有临时性信号偶尔被再悬浮的浮... 详细信息

本文研究了黄铁矿形成背景下波罗的海无潮的Oder河口中一个浅泻湖Achterwasser缺氧沉积物中痕量元素（V、Cr、Co、Cu、Zn、As、Cd、Ba.u.的早期成岩作用。溶解的主要氧化还原参数呈现出一个双层分布：具有临时性信号偶尔被再悬浮的浮泥层（FM）和之下已永久建立成岩序列的沉积物。强烈的微生物呼吸作用导致了FM最上部数毫米中氧气的迅速耗尽。FM中Mn、Fe和硫酸盐还原带互相重叠。永久缺氧沉积物部分出现低硫酸盐条件下河口沉积物的典型特征。黄铁矿化度（DOP）范围从FM中的50％30到50cm深度处〉90％的极高值。沉积物表层处的黄铁矿由硫化亚铁与中间态硫通过多硫途径形成。相比之下，之下的永久缺氧沉积物中强烈的黄铁矿化则是通过水相的铁硫配合物吸附到原已在表层形成的黄铁矿晶体上的矿物生长完成的。被研究的痕量元素呈现出上述成岩过程紧密耦合但有差异行为模式：（i）Zn、Cu和Cd从沉积物的薄有氧层中的有机质被释放并向上扩散穿过沉积物／水界面以及向下扩散以单硫化物的形式被捕获；（ii）V、Cr、Co和As在氢氧化铁和氢氧化锰的还原性溶解过程中被释放；（iii）u从孔隙水中的移除是由于u（VI）到u（IV）的还原，它与FM中的Fe还原同时发生；（iv）Ba的分布受硫酸盐还原带中自生重晶石的还原性溶解伴随的向上扩散和再沉积控制。痕量元素Co、Mn和As被黄铁矿的纳入最强烈，Cu和Cr中等，而u、Zn、Cd、V和Ba很少至可忽略。本研究观察到的趋势在很大程度上与前人的研究一致并可通过配位体交换的不同速率加以解释。配位体交换和由此导致沉积动力学的慢和快也被沿岩心向下（Mn、Cr、Co和As）增加或持续低（Zn、Cu、Cd）的孔隙水浓度所呈现。Co、Cu、Zn和As沿岩心向下增加的痕量元素黄铁矿化度（DTMP）与黄铁矿生长类似，都是由于已存在的黄铁矿物对硫化配位体或砷含氧阴离子的吸附。

关键词：痕量元素成岩作用黄铁矿沉积物河口

High rate of complete histopathological response in hepatocellular carcinoma patients after combined transarterial chemoembolization and stereotactic body radiation therapy

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World Journal of Gastroenterology 2021年第24期27卷 3630-3642页

作者： ulrike Bauer Sabine Gerum Falk Roeder Stefan Münch Stephanie E Combs Alexander B Philipp Enrico N De Toni Martha M Kirstein Arndt Vogel Carolin Mogler Bernhard Haller Jens neumann Rickmer F Braren Marcus R Makowski Philipp Paprottka Markus Guba Fabian Geisler Roland M Schmid Andreas umgelter ursula Ehmer Internal Medicine Ⅱ Klinikum rechts der IsarTechnical University of MunichMunich 81675Germany Department of Radiotherapy and Radiation Oncology University of SalzburgSalzburg 5020Austria Department of Radiation Oncology University Hospital of MunichCampus GroßhadernLMU MunichMunich 81377Germany Department of Radiation Oncology Klinikum rechts der IsarTechnical University of MunichMunich 81675Germany Department of Medicine II Liver CentreUniversity HospitalLMU MunichMunich 81377Germany Department of Gastroenterology Hepatology and EndocrinologyHannover Medical SchoolHannover 30625Germany Institute of Pathology Technical University of MunichMunich 81675Germany Institute of Medical Informatics Statistics and EpidemiologyKlinikum rechts der IsarTechnical University of MunichMunich 81675Germany Institute of Pathology Faculty of MedicineUniversity Hospital of MunichMunich 81377Germany Institute of Diagnostic and Interventional Radiology Klinikum rechts der IsarTechnical University of MunichMunich 81675Germany Institute of Diagnostic and Interventional Radiology Section for Interventional RadiologyKlinikum rechts der IsarTechnical University of MunichMunich 81675Germany Department of General- Visceral-Vascular-and Transplant-SurgeryUniversity hospital of MunichCampus GroßhadernLMU MunichMunich 81377Germany Emergency Department Vivantes hospital groupHumboldt hospitalBerlin 13509Germany

BACKGROuND Liver transplantation(LT)presents a curative treatment option in patients with early stage hepatocellular carcinoma(HCC)who are not eligible for resection or ablation *** to a risk of up 30%for waitlist drop-out upon tumor progression,bridging therapies are used to halt tumor *** chemoembolization(TACE)and less commonly stereotactic body radiation therapy(SBRT)or a combination of TACE and SBRT,are used as bridging therapies in ***,it remains unclear if one of those treatment options is *** analysis of explant livers after transplantation provides the unique opportunity to investigate treatment response by *** To analyze histopathological response to a combination of TACE and SBRT in HCC in comparison to TACE or SBRT *** In this multicenter retrospective study,27 patients who received liver transplantation for HCC were *** received either TACE or SBRT alone,or a combination of TACE and SBRT as bridging therapy to liver *** explants of all patients who received at least one TACE and/or SBRT were analyzed for the presence of residual vital tumor tissue by histopathology to assess differences in treatment response to bridging *** analysis was performed using Fisher-Freeman-Halton exact test,Kruskal-Wallis and Mann-Whitney-u *** Fourteen patients received TACE only,four patients SBRT only,and nine patients a combination therapy of TACE and *** were no significant differences between groups regarding age,sex,etiology of underlying liver disease or number and size of tumor ***,analysis of liver explants revealed that almost all patients in the TACE and SBRT combination group(8/9,89%)showed no residual vital tumor tissue by histopathology,whereas TACE or SBRT alone resulted in significantly lower rates of complete histopathological response(0/14,0%and 1/4,25%,respectively,P va.u.uSION Our data suggests th

关键词： Hepatocellular carcinoma Transarterial chemoembolization Stereotactic body radiation therapy Bridging therapy Liver transplantation

Influence of scanning force microscope loading force on mea.u.ement of ion-track diameter

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Nuclear Science and Techniques 1997年第3期 32-34页

作者： Wang Yu Gang, Zhao Wei Jiang ( Institute of Heavy Ion Physics, Peking university, Beijing 100871) Ackermann J, Müller A and neumann R (Gesellschaft für Schwerionenforschung (GSI), Planckstr. 1,D 64291 Darmstadt, Germany) InstituteofHeavyIonPhysics PekingUniversityBeijing100871 GesellschaftfuerSchwerionenforschung(GSI) p

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关键词： Ion track diameter Scanning force microscopy loading force