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Habitat use in eight populations of Sceloporus grammicus(Squamata:Phrynosomatidae)from the Mexican Plateau

Integrative Zoology 2017年第3期12卷 198-210页

作者： Adrian LEYTE-MANRIQUE Uriel HERNÁNDEZ-salinas Aurelio RAMÍREZ-BAUTISTA Vicente MATA-SILVA Jonathon C.MARSHALL Laboratorio de Biología Instituto Tecnológico Superior de SalvatierraSalvatierraGuanajuatoMexico Instituto Politécnico Nacional CIIDIR Unidad DurangoSigma 119Fraccionamiento 20 de Noviembre IIDurangoDurango 34220México Laboratorio de Ecología de Poblaciones Centro de Investigaciones BiológicasUniversidad Autónoma del Estado de HidalgoKm 4.5 carretera Pachuca-Tulancingo42184Mineral de la ReformaHidalgoMexico Department of Biological Sciences The University of Texas at El PasoEl PasoTexasUSA Department of Zoology Weber State University1415 Edvalson StreetOgdenUtahUSA

Studies on habitat use have often helped explain observed variation in morphology,behavior and reproductive characteristics among populations within a single *** we analyze morphological and ecological characteristics of individuals from the Sceloporus grammicus species complex from 7 different localities(CER,El Cerezo;PAC,Pachuca;HUI,Huichapan;EZA,Emiliano Zapata;SMR,San Miguel Regla;LMJ,La Mojonera;and LMZ,La Manzana)in the state of Hidalgo,and one locality(Cahuacán)in the State of Mexico.A canonical correspondence analysis(CCA)showed that females from PAC,EZA,LMZ,HUI,SMR and CAH populations use similar microhabitats characterized mostly by bare soil,in females from LMJ and CER use microhabitats characterized primarily by vegetation and *** were observed using 12 different types of *** regard to perch height use,the CCA showed that females from PAC,LMJ,LMZ,SMR,CER and CAH populations were correlated with height to nearest perch(HNP),in the rest of the females were not related to any perch use *** contrast,the CCA showed that males from PAC,LMJ and CAH were characterized by microhabitats with higher vegetal coverage,while males from LMZ and CER used microhabitats composed of bare soil,but males from HUI and SMR populations used microhabitats composed chiefly of bare soil and *** respect to perch height use,the CCA showed that males from PAC,LMJ,EZA and LMZ were correlated with distance to the nearest perch,but the rest of the males were not correlated with any perch use *** were observed in 9 different perch *** males were larger than the females in all morphological variables ***,in both sexes the snout-vent length is positively correlated with all morphological variables,and although both the slope and ordinate of the origin of all morphological variables were larger in males than females,the analysis of covariance indicated that there is no increase in the morphological variables with inc

关键词： canonical correspondence analyses habitat use morphology populations Sceloporus grammicus

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Pazopanib-induced posterior reversible encephalopathy syndrome with possible syndrome of inappropriate secretion of antidiuretic hormone: an incidental or pathophysiological association?

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Neural Regeneration Research 2020年第6期15卷 1166-1168页

作者： Jonathan Wong So Bérenger Largeau Frédérique Beau-salinas Stephan Ehrmann Christophe Magni Jérome Meunier CHR d’Orléans Service d’Oncologie MédicaleOrléansFrance CHRU de Tours Centre d’Investigation Clinique-CIC INSERM 1415ToursFrance CHRU de Tours Service de PharmacosurveillanceCentre Régional de Pharmacovigilance Centre-Val de LoireToursFrance Universitéde Tours INSERMCentre d’étude des pathologies respiratoires(CEPR)-UMR 1100CHRU de ToursService de Médecine Intensive RéanimationCIC INSERM 1415réseau CRICS-TRIGGERSEPToursFrance CHR d’Orléans Service de NeuroradiologieOrléansFrance

Introduction:Pazopanib is an oral protein kinase inhibitor(PKI)that targets vascular endothelial growth factor(VEGF)receptors,fibroblastic growth factor receptors,platelet-derived growth factor receptors,and stem cell factor that inhibits VEGF-induced cellular *** is approved for use in advanced renal cell carcinoma and subtypes of advanced soft-tissue sarcoma(Deguchi et al.,2018).Major adverse drug reactions of pazopanib include hypertension,high-grade hyponatremia and posterior reversible encephalopathy syndrome(PRES)(Berardi et al.,2016;Deguchi et al.,2018).In clinical trials,few investigations have been conducted to determine the aetiology of PKI-associated hyponatremia,the mechanism remains therefore *** rare cases of PKI-induced syndrome of inappropriate secretion of antidiuretic hormone(SIADH)(Largeau et al.,2019),and none with pazopanib,have been *** is a clinical and radiological entity where a bilateral white matter oedema,occurring predominantly in the posterior occipital and parietal lobes,is associated with several neurologic ***,a recent review suggests that SIADH could be a symptom of PRES(Largeau et al.,2019).To our knowledge,this is the first case published where pazopanib-induced PRES occurs contemporaneously with possible SIADH.

关键词： al. SIADH antidiuretic

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Induced Deactivation of Genes Encoding Chlorophyll Biosynthesis Enzymes Disentangles Tetrapyrrole- Mediated Retrograde Signaling

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Molecular Plant 2014年第7期7卷 1211-1227页

作者： Hagen Schlicke Annabel salinas Hartwig Vivien Firtzlaff Andreas S. Richter , Christine Glasser Klaus Maier Iris Finkemeier Bernhard Grimm Institute of Biology/Plant Physiology Humboldt University Berlin Philippstr. 13 Building 12 D 10115 Berlin Germany Helmholtz Zentrum Monchen Deutsches Forschungszentrum for Gesundheit und Umwelt (GmbH) Ingolstadter Landstr. 1 85764 Neuherberg Germany Max-Planck-lnstitute for Plant Breeding Research. Plant Proteomics and Mass Spectrometry Group Carl-von-Linne Weg 10 50829 Cologne Germany

In photosynthetic organisms, tetrapyrrole-mediated retrograde signals are proposed to contribute to a bal- anced nuclear gene expression （NGE） in response to metabolic activity in chloroplasts. We followed an experimental short- term approach that allowed the assessment of modified NGE during the first hours of specifically modified enzymatic steps of the Mg branch of tetrapyrrole biosynthesis, when pleiotropic effects of other signals can be avoided. In response to 24-h-induced silencing of CHLH, CHLM, and CHL27 encoding the CHLH subunit of Mg chelatase, the Mg protoporphyrin methyltransferase and Mg protoporphyrin monomethylester cyclase, respectively, deactivated gene expression rapidly led to reduced activity of the corresponding enzymes and altered Mg porphyrin levels. But NGE was not substantially altered. When these three genes were continuously inactivated for up to 4 d, changes of transcript levels of nuclear genes were determined. CHL27 silencing for more than 24h results in necrotic leaf lesions and modulated transcript levels of oxidative stress-responsive and photosynthesis-associated nuclear genes （PhANGs）. The prolonged deactivation of CHLH and CHLM results in slightly elevated transcript levels of PhANGs and tetrapyrrole-associated genes. These time-resolved studies indicate a complex scenario for the contribution of tetrapyrrole biosynthesis on NGE mediated by IO2-induced signaling and feedback-regulated ALA synthesis.

关键词： plastid signal transcription analysis retrograde signal tetrapyrrole metabolism Mg protoporphyrin.

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Numerical simulation of three-dimensional breaking waves and its interaction with a vertical circular cylinder

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Journal of Hydrodynamics 2017年第5期29卷 800-804页

作者： Zhihua Xie 吕林 Thorsten Stoesser 林建国 Dimitrios Pavlidis Pablo salinas Christopher C.Pain Omar K.Matar School of Engineering Cardiff UniversityCardiff CF24 3AAUK State Key Laboratory of Coastal and Offshore Engineering Dalian University of TechnologyDalian 116023China Department of Earth Science and Engineering Imperial College LondonLondonSW7 2AZUK Department of Chemical Engineering Imperial College LondonLondonSW7 2AZUK College of Environmental Science and Engineering Dalian Maritime UniversityDalian 116026China

Wave breaking plays an important role in wave-structure interaction. A novel control volume finite element method with adaptive unstructured meshes is employed here to study 3-D breaking waves. The numerical framework consists of a ＂volume of fluid＂ type method for the interface capturing and adaptive unstructured meshes to improve computational efficiency. The numerical model is validated against experimental measurements of breaking wave over a sloping beach and is then used to study the breaking wave impact on a vertical circular cylinder on a slope. Detailed complex interfacial structures during wave impact, such as plunging jet formation and splash-up are captured in the simulation, demonstrating the capability of the present method.

关键词： Breaking waves volume of fluid method 3-D simulation Navier-Stokes equation adaptive unstructured mesh

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A novel skeletal anchorage for rigid external distractor

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Plastic and Aesthetic Research 2017年第9期4卷 144-149页

作者： Rodrigo Farina Felipe salinas Department of Oral and Maxillofacial Surgery Hospital del SalvadorHospital San Borja ArriaránUniversidad de ChileSantiago 7510052Chile Department of Oral and Maxillofacial Surgery Hospital San Joséde MelipillaSantiago 9580000Chile

Aim: Maxillofacial surgery has always aimed to find alternative therapies to treat severe maxillary hypoplasia. Distraction osteogenesis of the midface has become the technique with the best functional and aesthetic results. Nevertheless, anchoring a distractor to the middle third of the face continues to involve complex planning. Plus, achieving the desired force vector can sometimes be cumbersome and uncomfortable. The aim of this study is to propose a novel skeletal anchorage technique for the rigid external distractor. Methods:Non-controlled, prospective study of 9 patients with severe midface hypoplasia who were treated with distraction osteogenesis using a rigid external distractor anchored to the infraorbital rims and the bilateral pyriform apertures. The activation phase started the first postoperative day at a rate of 1 mm per day. The consolidation period lasted 6 to 8 weeks. Results: Eight patients achieved the desired distraction objective (24.5 mm on average), with only 1 suffering a 5-mm relapse. None of the patients reported complications. Conclusion:Distraction osteogenesis of the midface by skeletal anchorage is an alternative method when treating patients with severe maxillary hypoplasia. It has significant advantages compared to traditional anchoring because it simplifies the procedure, diminishes the costs and complications.

关键词： Rigid external device rigid external distractor maxillary hypoplasia maxillary retrusion

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Timing of Proterozoic magmatism in the Sunsas belt, Bolivian Precambrian Shield, SW Amazonian Craton

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Geoscience Frontiers 2021年第6期12卷 277-293页

作者： Ingrid M.Nedel Reinhardt A.Fuck Amarildo S.Ruiz Gerardo R.Matos-salinas Alanielson da C.D.Ferreira Instituto de Geociências Universidade de Brasília(UnB)Brasília-DFBrazil Faculdade de Geociências Universidade Federal de Mato GrossoCuiabá-MTBrazil Instituto de Investigaciones Geológicas y del Medio Ambiente Universidad Mayor de San Andrés(UMSA)Pabellón GeologíaCalle 27Campus Universitario Cota CotaLa PazBolivia Department of Earth Sciences Stellenbosch UniversityPrivate Bag X1Matieland7602 StellenboschSouth Africa

We present new U–Pb zircon and monazite ages from the Sunsas belt granitic magmatism in Bolivia, SW Amazonian Craton. The geochronological results revealed four major magmatic events recorded along the Sunsas belt domains. The older igneous event formed a granitic basement coeval to the Rio Apa Terrane(1.95–1.85 Ga) in the southern domain. The second magmatic episode is represented by 1.68 Ga granites associated to the Paraguá Terrane(1.69–1.66 Ga) in the northern domain. The 1.37–1.34 Ga granites related to San Ignacio orogeny represent the third and more pervasive magmatic event, recorded throughout the Sunsas belt. Moreover, magmatic ages of ~1.42 Ga revealed that the granitogenesis associated to the Santa Helena orogeny also affected the Sunsas belt, indicating that it was not restricted to the Jauru Terrane. Lastly, the 1.10–1.04 Ga youngest magmatism was developed during the Sunsas orogeny and represents the final magmatic evolution related to Rodinia assembly. Likewise, the 1.95–1.85 and 1.68 Ga inherited zircon cores obtained in the ~1.3 Ga and 1.0 Ga granite samples suggest strong partial melting of the Paleoproterozoic sources. The 1079 ± 14 Ma and 1018 ± 6 Ma monazite crystallization ages can be correlated to the collisional tectono-thermal event of the Sunsas orogeny, associated to reactions of medium-to high-grade metamorphism. Thus, the Sunsas belt was built by heterogeneous 1.95–1.85 Ga and 1.68 Ga crustal fragments that were reworked at 1.37–1.34 Ga and 1.10–1.04 Ga related to orogenic collages. Furthermore, the 1.01 Ga monazite age suggests that granites previously dated by zircon can bear evidence of a younger thermal history. Therefore, the geochronological evolution of the Sunsas belt may have been more complex than previously thought.

关键词： SW Amazonian Craton Sunsas belt U–Pb geochronology Zircon Monazite

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Leuprolide acetate induces structural and functional recovery of injured spinal cord in rats

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Neural Regeneration Research 2015年第11期10卷 1819-1824页

作者： Carmen Díaz Galindo Beatriz Gómez-González Eva.salinas Denisse Calderón-Vallejo Irma Hernández-Jasso Eduardo Bautista J Luis Quintanar Laboratory of Neurophysiology Department of Physiology and Pharmacology Universidad Autónoma de Aguascalientes Area of Neuroscience Department of Reproductive Biology CBS Universidad Autónoma Metropolitana Laboratory of Immunology Department of Microbiology Centro de Ciencias Básicas Universidad Autónoma de Aguascalientes

Gonadotropin-releasing hormone（Gn RH） and its synthetic analog leuprolide acetate, a Gn RH agonist, have neurotrophic properties. This study was designed to determine whether administration of leuprolide acetate can improve locomotor behavior, gait, micturition reflex, spinal cord morphology and the amount of microglia in the lesion epicenter after spinal cord injury in rats. Rats with spinal cord compression injury were administered leuprolide acetate or saline solution for 5 weeks. At the 5th week, leuprolide acetate-treated rats showed locomotor activity recovery by 38%, had improvement in kinematic gait and exhibited voiding reflex recovery by 60%, as compared with the 1st week. By contrast, saline solution-treated rats showed locomotor activity recovery only by 7%, but voiding reflex did not recover. More importantly, leuprolide acetate treatment reduced microglial immunological reaction and induced a trend towards greater area of white and gray matter in the spinal cord. Therefore, leuprolide acetate has great potential to repair spinal cord injury.

关键词： nerve regeneration spinal cord injury leuprolide acetate gonadotropin-releasing hormone neurotrophic factor microglia micturition reflex gait inflammation neural regeneration

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国际教育作为软实力的组成部分：关于智利富布莱特项目的案例研究

国际教育作为软实力的组成部分：关于智利富布莱特项目的案例研究

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作者： ALEJANDRO salinas GOMEZ 吉林大学

学位级别：硕士

富布莱特项目是公共外交一个极好的例子,这个项目一直以来都是美国和智利之间文化、教育和科学关系的坚实基础。同样的,这个项目也被美国当作一个软实力工具来影响国际关系。在一个日益全球化的世界里,文化影响成为了一个在其他国家行... 详细信息

富布莱特项目是公共外交一个极好的例子,这个项目一直以来都是美国和智利之间文化、教育和科学关系的坚实基础。同样的,这个项目也被美国当作一个软实力工具来影响国际关系。在一个日益全球化的世界里,文化影响成为了一个在其他国家行使权力的可行选择,特别是当信息技术的快速发展已经使社会产生了重要变化。自从项目开始在智利运行以来,美国已经战略性地将国际教育作为软实力来影响、巩固关系,并签订有利于双方的经济合约,特别是提出议程和国家利益并且影响智利的重要决定。即使美国创造了富布莱特项目来推进文化和教育交流,并且促进两国间的共同理解,这种影响并没有如预想的那样进行,它已经变成了一种战略,倾向于向他人展示美国的文化、社会和科学模式。因此这个双边项目已经成为了美国外交政策的一个有效工具,通过交换使许多智利人能够接触扮演美国文化和社会大使角色的高校教师和学生,而从另一方面来讲,这些大使更加了解英语、其他习俗,特别是专心于北美文化的思考方式。富布莱特教育交换项目无疑被美国政府用于在智利产生文化影响,实现美国利益。这使得我们想到富布莱特项目和软实力之间的关系,这种关系呈现了国际教育和教育交换作为国际体系中的一种力量来塑造全球舞台,而这种力量能够通过观点、价值和外国文化传播来影响智利社会的观点和偏好。国际教育是美国政府利益的一种权力资源,这种资源影响着并能够改变那些有过在国外学习经历的人,国际教育如何转化为另一种权力资源,并且也在文化、科技和科学方面产生积极影响。最后,富布莱特项目能够影响受益人的生活和想法,而且考虑到美国教育部门在政府中有很大的自主权和独立地位,这个项目能够达到预期的结果。首先,本文描述了富布莱特项目作为国际教育对智利社会和拉丁美洲国家的文化、政治和科学发展所产生的影响。第二,本文将论述通过富布莱特项目,美国是否已经影响了智利的文化。本文也试图回答四个问题:美国和智利签订富布莱特项目的动机是什么?如果动机是经济秩序,这些国家在签订协议后能获得什么利益?第二个问题是富布莱特项目与软实力之间是什么关系?本文将论述美国如何通过软实力来实现目标,也会分析对社会和从富布莱特学者项目中受益的智利精英所产生的影响。一旦了解了软实力和国际教育的关系和目标,那就有必要回答第三个问题:富布莱特项目对于智利的文化、技术和科学发展有什么影响?通过回答这个问题,我们就会知道智利是如何从形成于美国名牌大学的这些精英中获益的,以及这些上等阶层是如何影响拉丁美洲国家的发展和进程的,以及他们是如何塑造政府和公共管理的。最后要去了解富布莱特计划在智利已经产生的影响,这对于解答本文的最后一个问题是很重要的:对于受益者来说,富布莱特项目的经历有什么效果?本文会表明参加富布莱特项目的经历是如何影响这些新智利精英的日常生活和思考方式的。在试图实现这些目标的过程中,本文意识到,在智利的富布莱特项目方面,并没有相关的文献或研究论文。因此作为案例研究,笔者将会通过追踪、分析并提供一个关于智利富布莱特项目的全面概述。本文也会试图分析国际教育和富布莱特项目是否可以被美国作为一个软实力工具,以及文化影响是否能成为对智利政府一个可行的选择。智利过去30年的政策强调社会的扩张,非国家行为体与利益集团开始更多地参与国际问题;这包括那些理解并掌握新规则和全球符号的新精英的参与。因此,这一案例研究就产生了以下问题:这些新精英的出现将会产生新的排外和社会不平等形式,较为传统的大学会垄断智利社会的未来社会阶层。本文包括五章。第一章概述包括关于美国和智利国际教育和软实力方面的文献。也显示了现有文献中智利国际教育的实证和演绎逻辑层面。然后介绍了富布莱特项目在智利的情况。最后,讨论了现有文献中存在的空白并为本文提供了逻辑思路。第二章被分为两节:第一节介绍富布莱特项目的背景,有助于更好地理解该项目。第二节将会介绍富布莱特项目是如何运作的,并介绍该项目的目标。而且从两个不同的、相互补充的视角进行分析:第一个视角是作为全球的教育项目,第二个视角是作为美国政府的一个公共外交项目。第三章被分成两节:第一节追溯了智利富布莱特项目的历史,包括所有的协议,列举了数据并进行了分析。第二节分析了智利富布莱特项目的运行情况,描述了诸如行政和融资等重要方面。第四章被分成三节:第一节论述了富布莱特项目对智利的影响,并且探讨了对于当地精英的影响,这些精英在智利融入国际经济的过程中起决定性作用。第二节探讨了智利富布莱特项目存在的问题。第三节提供了解决智利富布莱特项目存在问题的建议。第五章讨论和总结了之前的各章,并探讨和区分了美国富布莱特项目的软实力基础。基于各章中的理论和实践部分,问题的答案取决于对国际教育和软实力的解释和理解,还有对文献和数据的分析。国际教育和教育交换因此起到能够塑造全球舞台的强大引擎作用,通过理念、价值和国外文化的传播来运作

关键词：国际教育软实力公共外交对外政策文化和精英

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Generalized Formulation to Estimate a Potential Complex Function of a Flow past Multiple Cylinders

Generalized Formulation to Estimate a Potential Complex Func...

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The 2012 International Conference on Advanced Material and Manufacturing Science (ICAMMS 2012)

作者： Jan Mateu Armengol Carlos salinas Sedano State University of Campinas Mechanical Engineering Faculty ETSEIB Technical University of Catalonia(UPC)

This paper presents a generalized formulation to calculate an approximation of the complex potential function due to a flow past over any distribution of circular cylinders with different radius and *** validate the formulation,the stream function over different configurations of cylinders is *** an example,the potential complex function of three different configurations of cylinders in the z-plane is *** addition,in order to show the interference among the cylinders,the velocity and pressure distribution are also calculated.

关键词： Potential Flow Method of Complex Variables Flow past Multiple Cylinders

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Transcatheter aortic valve implantation:Current status and future perspectives

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World Journal of Cardiology 2011年第6期3卷 177-185页

作者： Pablo salinas Raul Moreno Jose L Lopez-Sendon Depart-ment of Interventional Cardiology University Hospital La Paz

Although surgical aortic valve replacement is the standard therapy for severe aortic stenosis(AS),about one third of patients are considered inoperable due to unacceptable surgical *** medical treatment alone these patients have a very poor prognosis with a mortality rate of 50%at 2 *** aortic valve implantation(TAVI)has been used in these patients,and has shown robust results in the only randomized clinical trial of severe AS treatment performed so *** this review,we will focus on the two commercially available systems:Edwards SAPIEN valve and CoreValve Revalving *** systems have demonstrated success rates of over 90%with 30-d mortality rates below 10%in the most recent transfemoral TAVI ***,long-term studies have shown that the valves have good haemodynamic *** studies are currently exploring the non-inferiority of TAVI procedures vs conventional surgery in high-risk patients,and long-term clinical results of the percutaneous *** this article we review the current status of TAVI including selection of patients,a comparison of available prostheses,results and complications of the procedure,clinical outcomes,and future perspectives.

关键词： Aortic valve stenosis Heart valve prosthesis Transcatheter aortic valve implantation Non-coronary intervention Aortic valve replacement Review

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