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Soleus arthrogenic muscle inhibition following acute lateral ankle sprain correlates with symptoms and ankle disability but not with postural control

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Journal of Sport and Health Science 2024年第4期13卷 559-568,F0003页

作者： Kyung-Min Kim Joo-Sung Kim Alan r.Needle Department of Sport Science Sungkyunkwan UniversitySuwon-si 16419Republic of Korea Department of Health and Human Performance Texas State UniversitySan MarcosTX 78666USA Department of Public Health&Exercise Science Appalachian State UniversityBooneNC 28608USA Department of rehabilitation Science Appalachian State UniversityBooneNC 28608USA

Background:Acute lateral ankle sprains(ALAS)are associated with long-term impairments and instability tied to altered neural *** muscle inhibition(AMI)has been observed in this population;however,relationships with injury-related impairments are unclear,potentially due to the resting,prone position in which AMI is typically *** AMI during bipedal stance may provide a better understanding of this ***:AMI was assessed in 38 young adults(19 ALAS within 72 h of injury:10 males,21.4±2.7 years;19 healthy controls:10 males,21.9±2.2 years;mean±SD)using the Hoffmann reflex(H-reflex)during bipedal *** stimulation was administered to identify the _(max)imal H-reflex(H_(max))and _(max)imal motor response(M_(max))from the soleus,fibularis longus,and tibialis anterior *** primary outcome measure was the H_(max)/M_(max) *** outcomes included acute symptoms(pain and swelling),postural control during bipedal stance,and self-reported ***:No significant group-by-limb interactions were observed for any ***,a significant group main effect was observed in the soleus muscle(F(1,35)=6.82,p=0.013),indicating significantly lower H_(max)/M_(max) ratios following ALAS(0.38±0.20)compared to healthy controls(0.53±0.16).Furthermore,lower H_(max)/M_(max) ratios in the soleus significantly correlated with acute symptoms and self-reported function but not with postural ***:This study supports previous evidence of AMI in patients with ALAS,providing insight into neurophysiologic impacts of musculoskeletal *** results suggest that assessing AMI in a standing position following acute injury may provide valuable insight into how AMI develops and guide potential therapeutic options to curb and offset the formation of joint instability.

关键词： Acute injuries Balance Hoffmann reflex Neural excitability Patient-reported outcomes

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Flexible neural probes:a review of the current advantages,drawbacks,and future demands

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Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2024年第2期25卷 153-167页

作者： Sara PIMENTA Joao r.FrEITAS JoséH.COrrEIA CMEMS-UMinho University of MinhoGuimarães4800-058Portugal LABBELS-Associate Laboratory Braga/GuimarãesPortugal

Brain diseases affect millions of people and have a huge social and economic *** use of neural probes for studies in animals has been the main approach to increasing knowledge about neural network ***,neuroscientists are trying to develop new and more effective therapeutic approaches to treating neurological *** implementation of neural probes with multifunctionalities(electrical,optical,and fluidic interactions)has been increasing in the last few years,leading to the creation of devices with high temporal and spatial *** the applicability of,and elements integrated into,neural probes has also led to the necessity to create flexible interfaces,reducing neural tissue damage during probe implantation and increasing the quality of neural acquisition *** this paper,we review the fabrication,characterization,and validation of several types of flexible neural probes,exploring the main advantages and drawbacks of these ***,future developments and applications are ***,this review aims to present the currently available flexible devices and future appropriate avenues for development as possible guidance for future engineered devices.

关键词： Brain knowledge Flexible interface Multifunctional probe

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Emerging potential of progranulin-dependent SorCS2 signaling in healthy and diseased nervous systems

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Neural regeneration research 2025年第9期20卷 2591-2593页

作者： Alena Salasova Anders Nykjær Danish research Institute of Translational Neuroscience DANDrITE-Nordic EMBL Partnership for Molecular Medicine and Centre of Excellence PROMEMODepartment of BiomedicineAarhus UniversityAarhusDenmark

The formation of the mammalian nervous system and its maturation into sensory,motor,cognitive,and behavioral circuits is a complex process that begins during early embryogenesis and lasts until young *** neurodevelopm... 详细信息

关键词： progr jointly CS2

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A Collocation Technique via Pell-Lucas Polynomials to Solve Fractional Differential EquationModel for HIV/AIDS with Treatment Compartment

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Computer Modeling in Engineering & Sciences 2024年第10期141卷 281-310页

作者： Gamze Yıldırım Suayip Yüzbası Department of Mathematics Faculty of ScienceAkdeniz UniversityAntalya07058Turkey Department of Mathematics Faculty of Basic ScienceGebze Technical UniversityKocaeli41400Turkey Department of Mathematics Faculty of ScienceBartın UniversityBartın74100Turkey

In this study,a numerical method based on the Pell-Lucas polynomials(PLPs)is developed to solve the fractional order HIV/AIDS epidemic model with a treatment *** HIV/AIDS mathematical model with a treatment compartment is divided into five classes,namely,susceptible patients(S),HIV-positive individuals(I),individuals with full-blown AIDS but not receiving ArV treatment(A),individuals being treated(T),and individuals who have changed their sexual habits sufficiently(r).According to the method,by utilizing the PLPs and the collocation points,we convert the fractional order HIV/AIDS epidemic model with a treatment compartment into a nonlinear system of the algebraic ***,the error analysis is presented for the Pell-Lucas approximation *** aim of this study is to observe the behavior of five populations after 200 days when drug treatment is applied to HIV-infectious and full-blown AIDS *** demonstrate the usefulness of this method,the applications are made on the numerical example with the help of *** addition,four cases of the fractional order derivative(p=1,p=0.95,p=0.9,p=0.85)are examined in the range[0,200].Owing to applications,we figured out that the outcomes have quite decent ***,we understand that the errors decrease when the value of N *** figures in this study are created in *** outcomes indicate that the presented method is reasonably sufficient and correct.

关键词： Collocation method fractional differential equations HIV/AIDS epidemic model Pell-Lucas polynomials

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Stable diffusion gradients in microfluidic conduits bounded by fluid walls

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Microsystems & Nanoengineering 2024年第3期10卷 357-367页

作者： Federico Nebuloni Cyril Deroy Peter r.Cook Edmond J.Walsh Department of Engineering Science Osney Thermo-Fluids InstituteUniversity of OxfordOxford OX20ESUK Sir William Dunn School of Pathology University of OxfordOxford OX13REUK

Assays mimicking in vitro the concentration gradients triggering biological responses like those involved in fighting infections and blood clotting are essential for biomedical *** assays prove especially attractive as they allow precise control of gradient shape allied to a reduction in *** microfluidic devices are fabricated using solid plastics that prevent direct access to responding ***-walled microfluidics allows the manufacture of circuits on standard Petri dishes in seconds,coupled to simple operating methods;cell-culture medium sitting in a standard dish is confined to circuits by fluid walls made of an immiscible *** develop and experimentally validate an analytical model of diffusion between two or more aqueous streams flowing at different rates into a fluid-walled conduit with the cross-section of a circular *** solid walls,fluid walls morph during flows as pressures fall,with wall shape changing down the *** model is validated experimentally for Fourier numbersrescein diffusing between laminar *** enables a priori prediction of concentration gradients throughout a conduit,so allowing rapid circuit design as well as providing bioscientists with an accurate way of predicting local concentrations of bioactive molecules around responsive and nonresponsive cells.

关键词： walls diffusion attractive

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Falcon Optimization Algorithm-Based Energy Efficient Communication Protocol for Cluster-Based Vehicular Networks

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Computers, Materials & Continua 2024年第3期78卷 4243-4262页

作者： Youseef Alotaibi B.rajasekar r.Jayalakshmi Surendran rajendran Department of Software Engineering College of ComputingUmm Al-Qura UniversityMakkah21955Saudi Arabia Department of Electronics and Communication Engineering Sathyabama Institute of Science and TechnologyChennai600119India Department of Computer Science and Engineering Panimalar Engineering CollegeChennai600123India Department of Computer Science and Engineering Saveetha School of EngineeringSaveetha Institute of Medical and Technical ScienceChennai602105India

rapid development in Information Technology(IT)has allowed several novel application regions like large outdoor vehicular networks for Vehicle-to-Vehicle(V2V)*** networks give a safe and more effective driving experience by presenting time-sensitive and location-aware *** communication occurs directly between V2V and Base Station(BS)units such as the road Side Unit(rSU),named as a Vehicle to Infrastructure(V2I).However,the frequent topology alterations in VANETs generate several problems with data transmission as the vehicle velocity differs with ***,the scheme of an effectual routing protocol for reliable and stable communications is *** research demonstrates that clustering is an intelligent method for effectual routing in a mobile ***,this article presents a Falcon Optimization Algorithm-based Energy Efficient Communication Protocol for Cluster-based routing(FOA-EECPCr)technique in *** FOA-EECPCr technique intends to group the vehicles and determine the shortest route in the *** accomplish this,the FOA-EECPCr technique initially clusters the vehicles using FOA with fitness functions comprising energy,distance,and trust *** the routing process,the Sparrow Search Algorithm(SSA)is derived with a fitness function that encompasses two variables,namely,energy and distance.A series of experiments have been conducted to exhibit the enhanced performance of the FOA-EECPCr *** experimental outcomes demonstrate the enhanced performance of the FOA-EECPCr approach over other current methods.

关键词： Vehicular networks communication protocol clustering falcon optimization algorithm routing

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Nonlinear corrections for the nuclear gluon distribution in eA processes

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Chinese Physics C 2024年第3期48卷 52-64页

作者： G.r.Boroun B.rezaei F.Abdi Department of Physics Razi UniversityKermanshah 67149Iran.

An analytical study with respect to the nonlinear corrections for the nuclear gluon distribution function in the next-to-leading order approximation at small x is *** consider the nonlinear corrections to the nuclear gluon distribution functions at low values of x and Q^(2) using the parametrization F_(2)(x,Q^(2))and the nuclear modification factors obtained from the Khanpour-Soleymaninia-Atashbar-Spiesberger-Guzey *** CT18 gluon distribution is used for the baseline proton gluon density at Q^(2)_(0)=*** discuss the behavior of the gluon densities in the next-to-leading order and the next-to-next-to-leading order approximations at the initial scale Q^(2)_(0),as well as the modifications due to the nonlinear *** find that the QCD nonlinear corrections are more significant for the next-to-leading order accuracy than the next-to-next-to-leading order for light and heavy *** results of the nonlinear GLr-MQ evolution equation are similar to those obtained with the rausch-Guzey-Klasen gluon upward and downward evolutions within the *** magnitude of the gluon distribution with the nonlinear corrections increases with a decrease in x and an increase in atomic number A.

关键词： gluon distribution nonlinear corrections light and heavy nuclei low x physics

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reflections on four decades of physical activity epidemiology

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Journal of Sport and Health Science 2024年第5期13卷 608-610页

作者： Barbara Sternfeld David r.Jacobs Jr. Division of research Kaiser Permanente Northern CaliforniaOaklandCA 94610USA Division of Epidemiology and Community Health School of Public HealthUniversity of MinnesotaMinneapolisMN 55454USA

In 1985,Public Health reports published a series of papers prepared for a workshop sponsored by the Centers for Disease Control and Prevention(CDC).1 Building on the seminal work of Jeremy Morris and ralph Paffenbarger Jr.,who were among the first to use epidemiological methods to study physical activity(PA),2,3 the workshop itself was the result of a growing scientific understanding of the importance of“physical fitness and exercise for improving the health of the public”.

关键词： semi workshop ralph

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Plant gene co-expression defines the biosynthetic pathway of neuroactive alkaloids

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Molecular Plant 2024年第3期17卷 372-374页

作者： Fang Liu' Alisdair r.Fernie Youjun Zhang Key Laboratory of Seed Innovation Institute of Genetics and Developmental BiologyChinese Academy of Sciences100101 BeijingChina Max Planck Institute of Molecular Plant Physiology Am Muhlenberg 114476 Potsdam-GolmGermany Center for Plant Systems Biology and Biotechnology 4000 PlovdivBulgaria University of Chinese Academy of Sciences 100049 BeijingChina

Transcriptomes comprise gene co-expression clustersor modules,showcasing distinct patterns of coordinated expression among groups of genes across independent biological samples(Serin et al.,2016).The"guilt-by-association"hypothesis suggests the functional importance of these clusters;for example,co-expressed genes associated with metabolism typically contain genes encoding several enzymes associated with the same pathways.

关键词： metabolism alkaloids

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Uncovering the epidemiology of bladder cancer in the Arab world: A review of risk factors, molecular mechanisms, and clinical features

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Asian Journal of Urology 2024年第3期11卷 406-422页

作者： Noura F.Abbas Marc r.Aoude Hampig r.Kourie Humaid OAl-Shamsi Department of Hematology-Oncology Hotel Dieu De France HospitalSaint Joseph University of BeirutRiad El SolhLebanon Department of Oncology Burjeel Cancer InstituteBurjeel Medical CityAbu DhabiUnited Arab Emirates Innovation and research Center Burjeel Cancer InstituteBurjeel Medical CityAbu DhabiUnited Arab Emirates College of Medicine University of SharjahSharjahUnited Arab Emirates Emirates Oncology Society DubaiUnited Arab Emirates College of Medicine Gulf Medical UniversityAjmanUnited Arab Emirates

Objective:Bladder cancer(BC)is a significant public health concern in the Middle East and North Africa,but the epidemiology and clinicopathology of the disease and contributors to high mortality in this region remain poorly *** aim of this systematic review was to investigate the epidemiological features of BC in the Arab world and compare them to those in Western countries in order to improve the management of this ***:An extensive electronic search of the PubMed/PMC and Cochrane Library databases was conducted to identify all articles published until May 2022,following the Preferred reporting Items for Systematic reviews and Meta-Analyses guidelines.A total of 95 articles were included in the final analysis after title,abstract,and full-text screening,with additional data obtained from the GLOBOCAN and WHO 2020 databases.

关键词： Bladder cancer Epidemiology risk factor Biomarker Schistosomiasis Arab world Urology

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