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Three Consecutive Monthly Intravitreal Ranibizumab for Choroidal Neovascularization in Central Serous Choriorethinopathy:A Case Report

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Open Journal of Ophthalmology 2012年第3期2卷 93-96页

作者： Kazim Erol Esin Sogutlu Sari Arif Koytak a.karacor D.T.Coban M.Bulut Ophthalmology Department Antalya Training and Research HospitalAntalyaTurkey Ophthalmology Department Kartal Training and Research HospitalIstanbulTurkey Ophthalmology Department Bezmialem Vakif UniversityIstanbulTurkey

Purpose: The author report the result of three consecutive monthly intravitreal ranibizumab injection for choroidal neovascularization (CNV) after bevacizumab injection for chronic central serous rethinopathy (CSR). Methods: A 48 year old man with chronic CSR was treated with intravitreal single dose 2.5 mg bevacizumab. One year after CNV was occurred, and three consecutive monthly intravitreal ranibizumab injections were performed. Results: Four weeks later the first ranibizumab dose, best corrected visual acuity was improved 20/80 to 20/20 and remained stable within one year. Conclusion: Repeat intravitreal ranibizumab injection in CNV after bevacizumab injection for chronic CSR appeared to be an effective treatment option.

关键词： Central Serous Choriorethinopathy Choroidal Neovascularization Ranibizumab

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Preanalytic Error Rates for the Central Laboratory of a Large-scale Public Hospital in Turkey

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Journal of Pharmacy and Pharmacology 2016年第7期4卷 318-321页

作者： Kemal TOrker ULUTAS Metin CELIK Beril AKCIMEN Esin Damla Z. karacor Fatma KARAZiNDiYANOGLU Antakya State Hospital Department of Medical Biochemistry Antakya 31000 Hatay TURKEY Osmaniye State Hospitals Central Clinical Laboratory Osmaniye 80000 Osmaniye TURKEY Kadirli State Hospital Central Biochemistry Laboratory Kadirli 80750 Hatay TURKEY

The pre and post analytical phase in a testing cycle contributes up to 93% of total laboratory errors. However, pre-analytical phase is primarily responsible for errors. Hence, it is of precise importance for the laboratory to study error occurrence rates during the testing cycle and implement a quality improvement plan to release an accurate result. The present study was conducted during the period Jan-Nov 2014 in the Central Clinical Lab in Osmaniye State Hospital, Turkey. During period of 11 months, 626897 samples were monitored for major preanalytical problems at the receiving counter of the Central Clinical Laboratory. Among all preanalytic laboratory errors, 35.4% of the errors were associated with clotted sample, 25.5% errors with inadequate sample, and 25.3% errors with hemolysed sample in the laboratory. Assessment considering the departments showed that emergency unit had the highest error rates (hemolysis: 52.5%, lipemic: 42.9%, damaged: 34.6%, clotted: 34.2%, inadequate: 26.8%, wrong material: 17.6%, wrong barcode: 16.7%). There was significant difference among the departments in terms of preanalytic errors (p < 0.001). Based on these observations, major preanalytic errors are of great concern and needs corrective approach via proper educational programs to related personals. If this area is ignored, that can lead to negative patient outcome. However, a better specimen quality and patient satisfaction are achieved with the high quality personal-based education regarding pre-analytical errors.

关键词：实验室分析误差率土耳其医院测试周期质量改进教育计划中心实验室

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