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Personalized Federated Learning for Heterogeneous Residential Load Forecasting

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Big Data Mining and Analytics 2023年第4期6卷 421-432页

作者： Xiaodong Qu Chengcheng Guan Gang Xie Zhiyi Tian keshav sood Chaoli Sun Lei Cui the Shanxi key Laboratory of Advanced Control and Equipment Intelligence Taiyuan University of Science and TechnologyTaiyuan 030024China the Faculty of Engineering and Information Technology University of Technology SydneyUltimo 2007Australia the Centre for Cyber Security Research and Innovation Deakin UniversityMelbourne 3125Australia the School of Computer Science and Technology Taiyuan University of Science and TechnologyTaiyuan 030024China

Accurate load forecasting is critical for electricity production,transmission,and *** learning(DL)model has replaced other classical models as the most popular prediction ***,the deep prediction model requires users to provide a large amount of private electricity consumption data,which has potential privacy *** nodes can federally train a global model through aggregation using federated learning(FL).As a novel distributed machine learning(ML)technique,it only exchanges model parameters without sharing raw ***,existing forecasting methods based on FL still face challenges from data heterogeneity and privacy ***,we propose a user-level load forecasting system based on personalized federated learning(PFL)to address these *** obtained personalized model outperforms the global model on local ***,we introduce a novel differential privacy(DP)algorithm in the proposed system to provide an additional privacy *** on the principle of generative adversarial network(GAN),the algorithm achieves the balance between privacy and prediction accuracy throughout the *** perform simulation experiments on the real-world dataset and the experimental results show that the proposed system can comply with the requirement for accuracy and privacy in real load forecasting scenarios.

关键词： load forecasting personalized federated learning differential privacy

Development of a Targeted Drug Delivery System for the Treatment of SARS-CoV-2

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Journal of Biosciences and Medicines 2022年第10期10卷 13-33页

作者： Sahil sood Lambert High School Duluth United States of America

SARS-CoV-2 has triggered a public health outbreak across the world, resulting in almost 5 million deaths as of January 2022. The arrival of vaccines has provided temporary relief, but these vaccines target the spike protein, which is highly prone to mutation, making it impossible to develop a long-term cure for the coronavirus. As such, there is an urgent need for site-specific inhibition of the virus in the respiratory tract, as well as targeting the internal proteins of the virus itself. Past literature has identified 3CLpro and PLpro as enzymes essential to the replication of the virus, as they assemble almost the entirety of the viral genome;as such, inhibiting the activity of these enzymes can stymie the spread of the virus. This project proposes the use of inhaled drug delivery to inhibit Covid-19 by synthesizing a formulation that can travel directly to the lungs via inhalation. In order to streamline synthesis, existing FDA-approved drugs were analyzed using computational docking software and in vitro assays for inhibitory activity against these two enzymes. High-performing drugs were then encapsulated in PLGA nanoparticles to synthesize a drug delivery system, which was tested and characterized in vitro. Furthermore, in an effort to improve this drug delivery system relative to other drug delivery systems, the use of enzyme nanomotors was explored as a way to increase the accuracy of delivery by using computational simulations that mimicked conditions in the human body to model the velocity and trajectory of the nanomotors.

关键词： Covid-19 SARS-CoV-2 PLGA Drug Delivery Chemotaxis

Hepatitis C Associated B-cell Non-Hodgkin Lymphoma:Clinical Features and the Role of Antiviral Therapy

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Journal of Clinical and Translational Hepatology 2015年第2期3卷 134-139页

作者： Syed Tasleem Gagan k sood Department of Surgery St.Luke's Center for Liver Disease Baylor College of Medicine Houston Texas USA Department of Surgery St.Luke's Center for Liver Disease Baylor College of Medicine Houston Texas USA Department of Gastroenterology and Hepatology Baylor College of Medicine Houston Texas USA

The link between chronic hepatitis C virus (HCV) infection and a subset of B-cell non-Hodgkin lymphomas (B-NHL) is strongly supported by epidemiological *** demonstrating complete regression of lymphoma after antiviral treatments suggests possible chronic antigenic stimulation for the origin of B-NHL and provides evidence for a virus-mediated lymphomagenesis.B-NHL is a heterogeneous group of lymphomas with varied clinical presentation and may be indolent or *** optimal management of HCV related B-NHL is not *** treatment may be sufficient for low-grade lymphomas,but chemotherapy is necessary in patients with high grade *** (IFN)-based antiviral treatment regimens for HCV infection are limited by poor tolerance and suboptimal antiviral *** approved novel direct acting antiviral (DAA) drugs are highly effective and *** has opened a new era for the treatment of HCV related B-NHL alone or in conjunction with *** of HCV associated B-NHL should be performed in an interdisciplinary approach in close consultation with hematologist and *** this review,we summarize data regarding clinical features and epidemiology of B-NHL and discuss novel therapeutic approaches,including DAAs,that may prove to be effective in the treatment of HCV associated lymphomas.

关键词： Hepatitis C Non-Hodgkin lymphoma Mixed cryoglobulinemia Rituximab

Fragment emission and critical behavior in light and heavy charged systems

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Chinese Physics C 2021年第1期45卷 215-225页

作者： Samiksha sood Rohit kumar Arun Sharma Sakshi Gautam Rajeev k.Puri Department of Physics Panjab UniversityChandigarh 160014India Department of Physics G.D.College.BillawarJammu 185204India

We study the emission of fragments in central collisions of light and heavily charged systems of^4+Ar+^45 Sc and^s4kr+^197 Au,respectively,using the Quantum Molecular Dynamics(QMD)model as the primary *** fragments are identified using an energy based clusterization algorithm,i.e.,the Simulated Annealing Clusterization Algorithm(SACA).The charge distributions of intermediate mass fragments[3≤Zf≤12]are fitted with power-law(∝Zf^-τ)and exp on ential(∝e^-λZf)fits in order to extract the parametersτandλ,whose minimum values are also sometimes linked with the onset of fragmentation or the critical point for a liquid-gas phase *** parameters such as the normalized second moment,,average size of the second largest cluster,phase separation parameter(Sp),bimodal parameter(P),information entropy(H),and Zipfs law are also analyzed to find the exact energy of the onset of *** detailed analysis predicts that an energy point exists between 20-23.1 MeV/nucleon,which is very close to the experimentally observed value of 23.9 MeV/nucleon for the^40Ar+^45Sc *** also find that the critical energy deduced using Zipfs law is higher than those predicted from other critical ***,no minimum is found for t values of the highly charged system of^84kr+^197Au,in agreement with experimental findings and various theoretical *** observe that the QMD+SACA model calculations are in agreement with the experimental *** agreement supports our results regarding the energy point of the liquid-gas phase transition and the onset of fragmentation.

关键词： heavy-ion collisions transport model clusterization algorithm Monte-Carlo technique li・quid-gas phase transition

Tribological response of waste tire rubber as micro-fillers in automotive brake lining materials

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Friction 2020年第6期8卷 1153-1168页

作者： Anand PAI Sayikumar SUBRAMANIAN Tribhuvan sood Department of Aeronautical and Automobile Engineering Manipal Institute of TechnologyManipal Academy of Higher Education ManipalKarnataka 576104lIndia Cranfield University CranfieldMilton KeynesBedfordshire MK430ALUK

Elastomeric materials show promise as potential micro-fillers in brake *** can provide vibration damping and acoustic advantages in intermittent and abrupt impact applications such as *** elastomeric material can be salvaged from non-biodegradable automotive tires,thereby providing an opportunity to reuse materials that will otherwise be discarded in *** tribological and thermomechanical performances of the waste tire rubber were assessed to determine their potential for use as micro-fillers in the brake linings of commercial vehicles with a gross weight less than 16 ***,the brake lining materials were fabricated with fine waste tire rubber particulates(WTRPs)as the micro-fillers,phenolic-R resin as the binder,graphite as the dry lubricant,laterite as the co-filler,and coconut coir for natural fiber *** effects of increasing the WTRP weight fraction on the brake response of the linings were analyzed,and the different compositions were benchmarked against a commercial brake *** characterization comprising compressive strength,hardness,density,and porosity studies were carried *** and wear characteristics of the linings were analyzed using a rotary tribometer with simultaneous thermal *** manufactured lining with 15 wt%WTRPs exhibited a mean friction coefficient of^0.38,a specific volumetric loss rate of 1,662μm3/(N?m),and improved thermal *** optical microscopy and scanning electron microscopy(SEM)with energy dispersive spectroscopy(EDS),wear surface morphology studies compared the relative development of primary and secondary plateaus and revealed the redistribution of wear debris,leading to the stability of the coefficient of friction.

关键词： automotive brakes elastomers graphite energy dispersive spectroscopy(EDS) scanning electron microscopy(SEM) wear mechanisms

Differential miRNA expression profiling of highly pathogenic avian influenza virus H5N1 infected chicken lungs reveals critical microRNAs,biological pathways and genes involved in the molecular pathogenesis

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Virologica Sinica 2022年第3期37卷 465-468页

作者： Anamika Mishra Muhasin Asaf Amod kumar Diwakar Dattatreya kulkarni Richa sood Sandeep Bhatia Bharat Bhushan Ashwin Ashok Raut Pathogenomics Laboratory ICAR-National Institute of High Security Animal DiseasesOIE referral laboratory for Avian InfluenzaBhopal 462021India ICAR-National Institute of High Security Animal Diseases OIE referral lab for Avian InfluenzaBhopal 462021India Division of Animal Genetics ICAR-Indian Veterinary Research InstituteBareilly 243122India

Dear Editor,Avian influenza is a highly contagious viral infection affecting the respiratory ***(miRNAs)are small,regulatory,endogenous,non-coding RNAs of~22 nt that regulate the gene expression of the target mRNAs by cleavage or translational *** are connected with the host response during avian influenza virus(AIV)infection(Wang et al.,2009,2012).In this study.

关键词： influenza endogenous pathogenesis

Impact of Living Donor Liver Transplantation on COVID-19 Clinical Outcomes from a Quaternary Care Centre in Delhi

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Journal of Clinical and Translational Hepatology 2022年第4期10卷 770-777页

作者： Imtiakum Jamir Niteen kumar Gaurav sood Ashish George Pankaj Lohia Samba Siva Rao Pasupuleti Amrish Sahney Manav Wadhawan Ajay kumar Abhideep Chaudhary Department of HPB Surgery and Liver Transplantation BLK Super Speciality HospitalNew DelhiIndia Department of Critical Care BLK Super Speciality HospitalNew DelhiIndia Department of Statistics Mizoram University(A Central University)Pachhunga University College CampusAizawlMizoramIndia Institute of Digestive and Liver Diseases BLK Super Speciality HospitalNew DelhiIndia

Background and Aims:The anticipated fear of serious out-comes in coronavirus infected liver transplant recipients led to disruption of transplant services *** aim of our study was to analyze COVID-19 severity in transplant recipients and to compare the difference of COVID-19 clinical outcomes in early(1 year)post-transplant ***:41 post-living donor liver transplant recipients with COVID-19 infection were studied retrospectively from 1st April 2020 to 28th February ***:The median age was 49.00 years with a male preponderance(80.49%).Fif-teen patients had infection within 1 year of transplant and 26 were infected after 1 year of *** overall median interval between transplantation and COVID-19 diagnosis was 816.00 *** and malaise were the common presenting *** most common associated comorbidities were diabetes mellitus(65.85%)and hypertension(46.34%).The severity of illness was mild in 28(68.29%),moderate in 4(9.76%),severe in 6(14.63%)and critical in 3(7.32%).To identify associated risk factors,we divided our patients into less severe and more severe *** for lymphopenia,there was no worsening of total bilirubin,transaminases,al-kaline phosphatase,and gamma-glutamyl transferase in the more severe ***(19.51%)patients required inten-sive care unit admission and three(7.32%)died,while none suffered graft *** recipients with early *** post-transplant COVID-19 infection,there were similar outcomes in terms of severity of COVID-19 illness,intensive care unit care need,requirement of respiratory support,and ***:Living donor liver transplantation can be per-formed during the COVID-19 pandemic without the fear of poor recipient outcome in cases of unfortunate contraction of severe acute respiratory syndrome coronavirus-2.

关键词： COVID-19 SARS-CoV-2 Living donor liver transplantation,LDLT Mortality Perioperative

Barnyard millet global core collection evaluation in the submontane Himalayan region of India using multivariate analysis

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The Crop Journal 2015年第6期3卷 517-525页

作者： Salej sood Rajesh k.khulbe Arun kumar R. Pawan k. Agrawal Hari D.Upadhyaya Indian Council of Agricultural Research-Vivekananda Institute of Hill Agriculture International Crop Research Institute for the Semi-Arid Tropics (ICRISAT)

Barnyard millet(Echinochloa spp.) is one of the most underresearched crops with respect to characterization of genetic resources and genetic enhancement. A total of 95 germplasm lines representing global collection were evaluated in two rainy seasons at Almora,Uttarakhand, India for qualitative and quantitative traits and the data were subjected to multivariate analysis. High variation was observed for days to maturity, five-ear grain weight, and yield components. The first three principal component axes explained 73% of the total multivariate variation. Three major groups were detected by projection of the accessions on the first two principal components. The separation of accessions was based mainly on trait morphology. Almost all Indian and origin-unknown accessions grouped together to form an Echinochloa frumentacea group. Japanese accessions grouped together except for a few outliers to form an Echinochloa esculenta group. The third group contained accessions from Russia, Japan, Cameroon, and Egypt. They formed a separate group on the scatterplot and represented accessions with lower values for all traits except basal tiller number. The interrelationships between the traits indicated that accessions with tall plants, long and broad leaves, longer inflorescences, and greater numbers of racemes should be given priority as donors or parents in varietal development initiatives. Cluster analysis identified two main clusters based on agro-morphological characters.

关键词： Agro-morphological variation Barnyard millet core germplasm Cluster analysis Echinochloa spp Principal component analysis

Do cardiopulmonary resuscitation real-time audiovisual feedback devices improve patient outcomes? A systematic review and metaanalysis

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World Journal of Cardiology 2023年第10期15卷 531-541页

作者： Nitish sood Anish Sangari Arnav Goyal Christina Sun Madison Horinek Joseph Andy Hauger Lane Perry Medical College of Georgia Augusta UniversityAugustaGA 30912United States Dental College of Georgia Augusta UniversityAugustaGA 30912United States Department of Chemistry and Physics Augusta UniversityAugustaGA 30912United States

BACkGROUND Cardiac arrest is a leading cause of mortality in America and has increased in the incidence of cases over the last several *** resuscitation(CPR)increases survival outcomes in cases of cardiac arrest;however,healthcare workers often do not perform CPR within recommended ***-time audiovisual feedback(RTAVF)devices improve the quality of CPR *** systematic review and meta-analysis aims to compare the effect of RTAVF-assisted CPR with conventional CPR and to evaluate whether the use of these devices improved outcomes in both in-hospital cardiac arrest(IHCA)and out-of-hospital cardiac arrest(OHCA)*** To identify the effect of RTAVF-assisted CPR on patient outcomes and CPR quality with in-and *** We searched PubMed,SCOPUS,the Cochrane Library,and EMBASE from inception to July 27,2020,for studies comparing patient outcomes and/or CPR quality metrics between RTAVF-assisted CPR and conventional CPR in cases of IHCA or *** primary outcomes of interest were return of spontaneous circulation(ROSC)and survival to hospital discharge(SHD),with secondary outcomes of chest compression rate and chest compression *** methodo-logical quality of the included studies was assessed using the Newcastle-Ottawa scale and Cochrane Collaboration’s“risk of bias”*** was analyzed using R statistical software *** were statistically significant if Pk ratio(RR)1.17(1.001-1.362);P=0.048]and in cases of IHCA[RR 1.36(1.06-1.80);P=0.002].There was no significant improvement in ROSC for OHCA(RR 1.04;0.91-1.19;P=0.47).No significant effect was seen in SHD[RR 1.04(0.91-1.19);P=0.47]or chest compression rate[standardized mean difference(SM

关键词： Real-time audiovisual feedback Cardiopulmonary resuscitation Cardiac arrest Return of spontaneous circulation Survival to hospital discharge Cardiopulmonary resuscitation quality