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Esophageal tuberculosis presenting with hematemesis

World Journal of Gastrointestinal Endoscopy 2013年第11期5卷 581-583页

作者： Samit S Jain Piyush O Somani Rajeshkumar C Mahey Dharmesh k Shah Qais Q Contractor Pravin M rathi Department of Gastroenterology Bai Yamunabai Laxman Nair HospitalTopiwala National Medical College Department of General Surgery Bai Yamunabai LaxmanNair HospitalTopiwala National Medical College

Esophageal tuberculosis is rare, constituting about 0.3% of gastrointestinal tuberculosis. It presents commonly with dysphagia, cough, chest pain in addition to fever and weight loss. Complications may include hemorrhage from the lesion, development of arterioesophageal fistula, esophagocutaneous fistula or tracheoesophageal fistula. There are very few reports of esophageal tuberculosis presenting with hematemesis due to ulceration. We report a patient with hematemesis that was due to the erosion of tuberculous subcarinal lymph nodes into the esophagus. A 15-year-old boy presented with hemetemesis as his only complaint. Esophagogastroduodenoscopy(EGD) revealed an eccentric ulcerative lesion involving 50% of circumference of the esophagus. Biopsy showed caseating epitheloid granulomas with lymphocytic infiltrates suggestive of tuberculosis. Computerised tomography of the thorax revealed thickening of the mid-esophagus with enlarged mediastinal lymph nodes in the subcarinal region compressing the esophagus along with moderate right sided pleural effusion. Patient was treated with anti-tuberculosis therapy(Rifampicin, Isoniazid, Pyrazinamide, Ethambutol) for 6 mo. Repeat EGD showed scarring and mucosal tags with complete resolution of the esophageal ulcer.

关键词： Esophageal tuberculosis Esophagogastroduodenoscopy Hematemesis

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红姜叶提取物所含化学成分的抗肿瘤及抗菌作用(英文)

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中西医结合学报 2012年第12期10卷 1460-1464页

作者： Chinthamony Arul Raj Dominic Sophia Paramasivam Ragavendran Thangarajan Starlin Muthian Ahalliya rathi Velliyur kanniappan Gopalakrishnan Department of Biochemistry Karpagam University Department of Bioinformatics Karpagam University Department of Biochemistry Sree Narayana Guru College

目的:研究红姜叶提取物中的化学成分的抗肿瘤及抗菌活性。方法:用自来水充分洗净红姜叶,晾干后制成粉剂,用连续溶剂系统提取其化学成分。对植物化学成分进行评估,运用纸片扩散法检测植物提取物的抗菌活性,利用四甲基偶氮唑盐比色法检测... 详细信息

目的:研究红姜叶提取物中的化学成分的抗肿瘤及抗菌活性。方法:用自来水充分洗净红姜叶,晾干后制成粉剂,用连续溶剂系统提取其化学成分。对植物化学成分进行评估,运用纸片扩散法检测植物提取物的抗菌活性,利用四甲基偶氮唑盐比色法检测植物叶子的乙酸乙酯提取物的抗肿瘤作用。结果:红姜叶经乙酸乙酯提取后,能最大限度得到有效的植物化学成分。不同浓度的红姜叶植物提取物抑制细菌的区域为5～14mm;并且在48h内、植物提取物半数抑制浓度为110.25μg/mL时表现出抗PA1卵巢癌细胞株活性,且细胞数量呈剂量依赖性递减。结论:红姜叶的乙酸乙酯提取物中的化学成分可有效抑制细菌活性,并具有抗肿瘤的作用。

关键词：山姜属植物提取物抗菌药抗肿瘤药体外研究

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Unusual complication of amebic liver abscess: Hepatogastric fistula

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World Journal of Gastrointestinal Endoscopy 2015年第9期7卷 916-919页

作者： Sunil V Pawar Vinay G Zanwar Pravir A Gambhire Ashok R Mohite Ajay S Choksey Pravin M rathi Dileep S Asgaonkar Department of Gastroenterology 7th floor OPD building Topiwala National Medical College and Bai Yamunabai Laxman Nair HospitalMumbai Central Department of Medicine 1st floor College buildingTopiwala National Medical College and Bai Yamunabai Laxman Nair HospitalMumbai Central

Amebic liver abscess is a parasitic disease which is often encountered in tropical countries. A hepatogastric fistula secondary to an amebic liver abscess is a rare complication of this disease and there are only a handful of reported cases in literature. Here we present a case of an amebic liver abscess which was complicated with the development of a hepatogastric fistula. The patient presented with the Jaundice, pain and distension of abdomen. The Jaundice and pain improved partially after he had an episode of brownish black colored increase in frequency of stools for 5 to 6 d. Patient also had ascites and anemia. He was a chronic alcohol drinker. Esophagogastroduodenoscopy performed in view of the above findings. It showed a fistulous opening with bilious secretions along the lesser curvature of the stomach. On imaging multiple liver abscesses seen including one in sub capsular location. The patient was managed conservatively with antiamebic medications along with proton pump inhibitors. The pigtail drainage of the sub capsular abscess was done. The patient improved significantly. The repeat endoscopy performed after about two months showed reduction in fistula size. A review of the literature shows that hepatogastric fistulas can be managed conservatively with medications and drainage, endoscopically with biliary stenting or with surgical excision.

关键词： Amebic liver abscess Hepatogastric fistula Esophagogastroduodenoscopy Entaameba histolytica Ultrasonography Computed tomography

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中美互换摘要

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中华高血压杂志 2020年第8期28卷 798-798页

作者：袁源(译) 叶鹏(校) rathi N Whelton Pk Chertow GM Cushman WC Cheung Ak Wei G Boucher R kimmel PL Bress AP kramer HJ Al-Marji C Greene T Beddhu S Dos Santos ESG De Souza OF 不详

糖尿病前期是否影响强化降压对肾脏事件的作用?美国成人>1/3处在糖尿病前期,且普遍伴发高血压。方法:研究者通过对收缩压干预试验(systolic blood pressure intervention trial, SPRINT)事后比较分析(post-hoc analysis),评估糖尿病前... 详细信息

糖尿病前期是否影响强化降压对肾脏事件的作用?美国成人>1/3处在糖尿病前期,且普遍伴发高血压。方法:研究者通过对收缩压干预试验(systolic blood pressure intervention trial, SPRINT)事后比较分析(post-hoc analysis),评估糖尿病前期是否影响强化降压对慢性肾脏病(chronic kidney disease,CkD)及急性肾损伤(acute kidney injury,AkI)的作用。

关键词：糖尿病前期慢性肾脏病美国成人强化降压

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