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Plasma Science and Technology 2010年第5期12卷 608-613页

作者： I.Y.Y.BU a.j.flewitt W.I.MILINE Department of Microelectronics Engineering National Kaohsiung Marine University Electrical Engineering Division Engineering Department Cambridge University

Deposition of nanocrystalline silicon （nc-Si） on glass at very low temperatures by electron cyclotron resonance （ECR） plasma enhanced chemical vapour deposition （PECVD） was investigated. It was shown that nc-Si could be deposited from hydrogen diluted silane gas at a substrate temperature of 80℃ with a crystalline fraction up to 80% and a lateral grain size of around 50 nm. This was achieved by growing the nc-Si in a low pressure regime which ensured that mono-silyl species were the dominant deposition precursor. Furthermore, a high flux of energetic hydrogen ions was required to induce crystallisation of the silicon material through a chemical annealing process.

关键词： low temperature nanocrystalline silicon ECR

Modelling of Equilibrium Grain Boundary Solute Segregation under Irradiation

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journal of Materials Science & Technology 2005年第2期21卷 196-200页

作者： ShenhuaSONG R.G.Faulkner P.E.j.flewitt LuqianWENG DivisionofMaterialsScienceandEngineering ShenzhenGraduateSchoolHarbinInstituteofTechnologyShenzhenUniversityTownXiliShenzhen518055China InstituteofPolymerTechnologyandMaterialsEngineering LoughboroughUniversityLoughboroughLeicestershireLEll3TUUK InterfaceAnalysisCentre UniversityofBristolBristolBS28BSUK

Both radiation-induced excess vacancies and solute-interstitials may enhance solute diffusion. The radiation-enhanced solute diffusion promotes the kinetic process of equilibrium segregation. This effect is especially considerable in the low temperature range. As a complement to modelling of radiation-induced non-equilibrium segregation, the radiation-created vacancy and solute-interstitial-accelerated equilibrium grain boundary solute segregation were theoretically treated. The models were applied to phosphorus segregation in α-Fe subjected to neutron irradiation.

关键词： Radiation Point defects Diffusion Grain boundary Segregation

Determination of Neutron Irradiation-Induced Phosphorus Segregation on Grain Boundaries in a P-doped 2.25Cr1Mo Steel

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journal of Materials Science & Technology 2004年第1期20卷 81-85页

作者： ShenhuaSONG R.G.Faulkner P.E.j.flewitt DongdongSHEN jingLIU ZexiYUAN SchoolofMaterialsandMetallurgy WuhanUniversityofScienceandTechnologyWuhan430081China InstituteofPolymerTechnologyandMaterialsEngineering LoughboroughUniversityLoughboroughLeicestershireLEll3TUUK BerkeleyCentre BNFLMagnoxGenerationBerkeleyGloucestershireGL139PBUK

Irradiation-induced impurity segregation to grain boundaries is one of the important radiation effects on materials. For this reason, phosphorus segregation to prior austenite grain boundaries in a P-doped 2.25Cr1Mo steel subjected to neutron irradiation is examined using field emission gun scanning transmission electron microscopy (FEGSTEM) with energy dispersive X-ray microanalysis (EDX). The steel samples are irradiated around 270 and 400℃, respectively. The irradiation dose rate and dose are -1.05×10-8 dpa/s and -0.042 dpa respectively for 270℃ irradiation, and 1.7×10-8 dpa/s and 0.13 dpa respectively for 400℃ irradiation. The FEGSTEM results indicate that there is no apparent phosphorus segregation during 270℃ irradiation but there is some during 400℃ irradiation.

关键词： Neutron irradiation Segregation Grain boundary Phosphorus

Apples to oranges:environmentally derived,dynamic regulation of serotonin neuron subpopulations in adulthood?

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Neural Regeneration Research 2025年第9期20卷 2596-2597页

作者： Christopher j.O’Connell Matthew j.Robson Department of Genetics College of MedicineHarvard UniversityBostonMAUSA james L.Winkle College of Pharmacy Division of Pharmaceutical SciencesUniversity of CincinnatiCincinnatiOHUSA Neuroscience Graduate Program College of MedicineUniversity of CincinnatiCincinnatiOHUSA

Traumatic brain injury(TBI)is a public health problem with an undue economic burden that impacts nearly every age,ethnic,and gender group across the globe(Capizzi et al.,2020).TBIs are often sustained during a dynamic range of exposures to energetic environmental forces and as such outcomes are typically heterogeneous regarding severity and pathology(Capizzi et al.,2020).

关键词： sustained orange dynamic

A Model to Describe the Fracture of Porous Polygranular Graphite Subject to Neutron Damage and Radiolytic Oxidation

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Computers, Materials & Continua 2016年第3期51卷 163-185页

作者： G.Smith E.Schlangen P.E.j.flewitt A.G.Crocker A.Hodgkins Interface Analysis Centre School of PhysicsUniversity of BristolBristolBS81TLUK Faculty of Civil Engineering and Geosciences Delft University of TechnologyDelftNetherlands HH Wills Physics Laboratory School of PhysicsUniversity of BristolBristolBS81TLUK Physics Department University of SurreyGuildfordGU27XH AMEC Clean Energy now AMEC Foster-WheelerWalton House404 Faraday StreetBirchwood ParkWarringtonCheshireWA36GAUK

Two linked models have been developed to explore the relationship between the amount of porosity arising in service from both radiolytic oxidation and fast neutron damage that influences both the strength and the force-displacement(load-displacement)behaviour and crack propagation in pile grade A graphite used as a nuclear reactor moderator *** models of the microstructure of the porous graphite for both unirradiated and irradiated graphite are *** form the input for the second stage,simulating fracture in lattice-type finite element models,which predicts force(load)-displacement and crack propagation *** comprising aligned filler particles,typical of needle coke,in a porous matrix have been *** purpose was to isolate the contributions of filler particles and porosity to fracture strength and crack paths and consider their implications for the overall failure of reactor core graphite.

关键词： Reactor core graphite Modelling microstructure FE lattice model Fracture strength Crack path

Gene therapy for spinal muscular atrophy:perspectives on the possibility of optimizing SMN1 delivery to correct all neurological and systemic perturbations

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Neural Regeneration Research 2025年第7期20卷 2011-2012页

作者： Sharon j.Brown Rafael j.Yáñez-Muñoz Heidi R.Fuller School of Pharmacy and Bioengineering Keele UniversityKeeleUK Wolfson Center for Inherited Neuromuscular Disease TORCH BuildingRJAH Orthopaedic HospitalOswestryUK *** Center of Gene and Cell TherapyDepartment of Biological SciencesSchool of Life Sciences and the EnvironmentRoyal Holloway University of LondonEghamUK

Spinal muscular atrophy(SMA)is a genetic condition that results in selective lower motor neuron loss with concomitant muscle weakness and *** genetic cause of SMA was understood in 1995 when loss or impairment of the survival motor neuron 1(SMN1)gene was identified as the main contributing factor(Lefebvre et al.,1995).This,in combination with the discovery that humans have a“back-up”gene,SMN2,which can produce low levels(approximately 10%)of the full-length functional SMN protein,has led to the generation of SMA-specific gene *** was traditionally classified according to age of symptom onset and developmental milestones achieved,with life expectancy and severity varying between ***,SMN2 copy number is used as a proxy for the prediction of disease severity,with higher SMN2 copy number typically being associated with reduced severity of SMA,although this relationship is not absolute:some individuals with low SMN2 copy number have less severe SMA phenotypes and vice ***,the etiology of SMA is further complicated by other factors,such as non-typical nucleotide variants and SMN2-independent modifiers of disease severity.

关键词： atrophy traditionally absolute

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中子辐照诱导压力容器钢中磷的偏析

金属学报 2005年第1期41卷 79-83页

作者：吕铮 R.G.Faulkner P.E.j.flewitt IPTME Loughborough UniversityLoughboroughLeicestershireLE11 3TUUK Stuctural Integrity BNFL Magnox GenerationBerkeley CentreBerkeleyGlos.GL13 9PBUK.

中子辐照引起的核反应堆压力容器钢中磷的晶间偏析是导致核反应堆压力容器脆性断裂的主要因素之一.本文提出了预测核反应堆压力容器钢中杂质元素(主要是磷)晶间非平衡偏析的溶质拖拽模型,并且与速率理论模型进行了对比.该模型的预测 ... 详细信息

中子辐照引起的核反应堆压力容器钢中磷的晶间偏析是导致核反应堆压力容器脆性断裂的主要因素之一.本文提出了预测核反应堆压力容器钢中杂质元素(主要是磷)晶间非平衡偏析的溶质拖拽模型,并且与速率理论模型进行了对比.该模型的预测结果与最近发表的压力容器钢(包括C-Mn和MnMoNi钢)的一些实验数据一致.

关键词：辐照偏析模拟铁素体钢

Women in visual neural regeneration research

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Neural Regeneration Research 2025年第2期20卷 489-490页

作者： Tonia S.Rex David j.Calkins Vanderbilt Eye Institute Vanderbilt University Medical CenterNashvilleTNUSA

The year 2024 marks the 60^(th)anniversary of Title IX and 25 years since the New York Times revealed bias against female faculty members at the Massachusetts Institute of *** take an opportunity here to examine the state of gender bias in a relatively new yet already prominent field,neural regeneration in the visual system,for which there is a well-defined context useful for this *** National Eye Institute(NEI)provided the first round of research funding for its Audacious Goals Initiative(AGI)on visual neural regeneration in 2013 and the last round in ***,we focus on this *** sources included PubMed,the National Science Foundation(NSF),the NEI,the Blue Ridge Institute for Medical Research and data from the major professional organization for eye and vision research,the Association for Research in Vision and Ophthalmology(ARVO).

关键词： neural visual Times

Generation of brain vascular heterogeneity:recent advances from the perspective of angiogenesis

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Neural Regeneration Research 2025年第7期20卷 2013-2014页

作者： Nathanael j.Lee Ryota L.Matsuoka Department of Neurosciences Lerner Research InstituteCleveland ClinicClevelandOHUSA Department of Molecular Medicine Cleveland Clinic Lerner College of MedicineCase Western Reserve UniversityClevelandOHUSA

Heterogeneous proper t i es of vascular endothelial cells in the brain:The brain displays large energy dynamics and consumption,and this high level of metabolic demands is fulfilled by a continuous supply of glucose and oxygen through its vascular *** vasculature consists of highly divergent blood vessel branches,giving rise to a dense network of capillaries that supply blood to all cells across the *** elaborated vascular network is thought to develop via angiogenesis,a process in which new blood vessels grow from pre-existing *** capillaries exhibit organotypic features distinct from other tissues and are formed primarily by two major endothelial cell(EC)types:those that form the semi-permeable blood-brain barrier(BBB)and those that develop highly permeable pores known as fenestrae(Matsuoka et al.,2022).The structural and functional differences between BBB and fenestrated vascular ECs represent a fundamental feature of brain vasculature and form the foundation for both brain function and homeostasis.

关键词： angiogenesis homeostasis network

Neuroprotection by resveratrol-glucuronide and quercetin-glucuronide via binding to polyphenol-and glycosaminoglycan-binding sites in the laminin receptor

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Neural Regeneration Research 2025年第3期20卷 819-820页

作者： Rayudu Gopalakrishna jennifer Aguilar Emily Lee William j.Mack Department of Integrative Anatomical Sciences Keck School of MedicineUniversity of Southern CaliforniaLos AngelesCAUSA Department of Neurological Surgery Keck School of MedicineUniversity of Southern CaliforniaLos AngelesCAUSA

The dietary polyphenolic compounds resveratrol and quercetin prevent neurodegenerative diseases in experimental models;however, they reach the brain only in nanomolar concentrations in the glucuronidated and sulfated ... 详细信息

关键词： resveratrol molar dated