检索结果-南通市图书馆

国际医学放射学杂志 2022年第4期 492-492页

作者： A.Pons -Escoda A.Garcia -Ruiz P.Naval -Baudin F.Grussu J.J.S.Fernandez a.c.simo 张雅欣王天达

摘要目的常规动态磁敏感对比-灌注加权成像（DScPWI）分析基于具体参数和测量值，但基于时间-信号强度曲线所有点和兴趣区所有体素的方法有可能提供更完善信息

关键词：

Triterpenoids and Semisynthetic Derivatives with Antimicrobial Activities from the Leaves of <i>caloncoba glauca</i>(Flacourtiaceae)

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Advances in Biological chemistry 2021年第4期11卷 149-164页

作者： James D. simo Mpetga Arno R. Nanfack Donfack Jean-De-Dieu Tamokou Irene chinda Kengne Pierre Tane Xiao-Jiang Hao Mathieu Tene Natural Products chemistry Research Unit Department of Chemistry Faculty of Science University of Dschang Dschang Cameroon Research Unit of Microbiology and Antimicrobial Substances Department of Biochemistry Faculty of Science University of Dschang Dschang Cameroon State Key Laboratory of Phytochemistry and Plant Resources in West china Kunming Institute of Botany Chinese Academy of Sciences Kunming China

chemical investigation of the MeOH extract from the leaves of c. glauca yielded nine known triterpenoids (1-9) belonging to the cycloartane and friedelane series. Two of these compounds namely glaucartanoic acid A (1)... 详细信息

Chemical investigation of the MeOH extract from the leaves of C. glauca yielded nine known triterpenoids (1-9) belonging to the cycloartane and friedelane series. Two of these compounds namely glaucartanoic acid A (1) and 3β,21β-dihydroxy-30-nor-(D:A)-friedoolean-20(29)-en-27-oic acid (5) were subjected to chemical derivatizations and afforded five new derivatives: diacetylglaucartanoic acid A (1a), 24-acetylglaucartanoic acid A (1b), glaucartanoic acid A methyl ester (1c), 24-methoxyglaucartanoic acid A methyl ester (1d), and 3β,21β-diacetoxy-30-nor-(D:A)-friedoolean-20(29)-en-27-oic acid (5a

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

远心补偿像面稳定的共心多尺度系统设计

光学学报 2022年第14期42卷 162-172页

作者：李京宸张坤王思沫刘吉潇杨聚圃严伟中国科学院光电技术研究所环境光学研究院四川成都610209 中国科学院大学北京100049

目前的共心多尺度系统普遍存在子相机像面不稳定的问题,这一问题直接导致了在后续的图像拼接中易于出现图像拼接错位,严重影响系统成像质量。针对这一问题,提出了一种基于像方远心光路的方法,该方法提高了子相机像面的稳定性,为后续的... 详细信息

目前的共心多尺度系统普遍存在子相机像面不稳定的问题,这一问题直接导致了在后续的图像拼接中易于出现图像拼接错位,严重影响系统成像质量。针对这一问题,提出了一种基于像方远心光路的方法,该方法提高了子相机像面的稳定性,为后续的图像拼接减轻了压力。首先对错位现象出现的原因进行了理论分析,从理论层面分析了引入像方远心光路对改善成像系统的作用,最终设计了成像性能优异的基于像方远心光路的共心多尺度成像系统,其焦距为60 mm,F数为3,远心度小于0.2 mrad,总视场为70°,各视场弥散斑半径小于所选探测器的像元尺寸,在奈奎斯特频率为108 lp/mm处各视场的调制传递函数均大于0.6。像方远心结构的共心多尺度成像系统可以从光学结构部分改善子相机像面不稳定的问题,从而提高后端图像拼接的拼接质量和拼接效率,为后续的共心多尺度系统设计提供了更多的思路和技术途径,具有重要的理论和实践意义。

关键词：光学设计像面稳定补偿像方远心光路共心多尺度成像系统

同方期刊数据库

小世界网络与创新绩效的关系:研究综述与展望

在线全文

学校读者我要写书评

暂无评论

中国人力资源开发 2015年第23期32卷 23-27页

作者：王崇锋亓彬程铭康思默青岛大学商学院青岛大学数学科学学院

小世界网络是创新网络的重要组成部分。小世界网络尤其是小世界性与创新绩效的关系是研究创新的新视角。然而已有研究更多的把重点放在小世界网络的应用,缺乏从网络指标层面对小世界网络与创新的关系进行更深层的分析与研究。因此,本文... 详细信息

小世界网络是创新网络的重要组成部分。小世界网络尤其是小世界性与创新绩效的关系是研究创新的新视角。然而已有研究更多的把重点放在小世界网络的应用,缺乏从网络指标层面对小世界网络与创新的关系进行更深层的分析与研究。因此,本文从小世界网络的概念及其特征出发,以小世界网络指标与创新的关系为切入点对小世界网络与创新绩效的关系进行分析。

关键词：小世界网络特征路径长度聚集度创新绩效

Antiradical, Anti-inflammatory and Antifungal Activities of Essential Oils of Two Aromatic Plants： Apium graveolens （Apiaceae） and Thymus vulgaris （Lamiaceae）

在线全文

学校读者我要写书评

暂无评论

Journal of Life Sciences 2015年第2期9卷 51-64页

作者： Marguerite simo Kamdem Modeste Lambert Sameza Pierre Michel Jazet Dongmo Fabrice Fekam Boyom Issakou Bakargna-Via Jean Baptiste Hzounda Fokou Ide Flavie Kenfack Tsague Elisabeth Zeuko'o Menkem Paul Henri Amvam Zollo chantal Menut Department of Biochemistry Faculty of Science University of Yaounde I Yaounde P. O Box 812 Cameroon Department of Biochemistry Faculty of Science University of Douala Douala P.O Box 24157 Cameroon ENSAL University of Ngaoundere Ngaoundere P.O Box 455 Cameroon IBMM Montpellier-UMR 5247 Faeulte de Pharmaeie 15 Avenue Charles Flahault Montpellier 34093 France

The outbreak of oxidative stress, inflammatory diseases and mycoses, constitute an important public health problem. This could be due to the increase of risk factors, side effects and expensive therapeutic molecules available. In the aim to find the potential spring of new therapeutic molecules with efficient and wide spectrum of action, the antiradical, anti-inflammatory and antifungal activities of two essential oils were evaluated. The essential oils were extracted by hydrodistillation. The antiradical activity was evaluated to use DPPH （2,2-diphenyl-l-picrylhydrazyl） scavenging method and the anti-inflammatory activity was determined using the enzymatic method. The disc diffusion and dilution methods were used to evaluate growth inhibition of three yeasts, three moulds and three dermatophytes. The yields of extraction of Apium graveolens and Thymus vulgaris essential oils were 0.14% and 0.32% respectively. These essential oils showed antiradical properties with respective Sc50 of 0.41 and 0.06 g/L for Apium graveolens and Thymus vulgaris. Only Thymus vulgaris presented an anti-inflammatory activity with an Ic50 of 0.19 g/L. cryptococcus neoformans was the most susceptible fungal strain while c. albicans was the most resistant one. The results were compared with the standard antifungal. These results show that these essential oils could be exploited as potential spring of molecules endowed with antiradical, anti-inflammatory and antifungal activities.

关键词： Essential oil antiradical anti-inflammatory antifungal.

A Retrospective Analysis of the Patterns and Outcomes of Tile B and Tile c Pelvic Fractures in cameroon

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Open Journal of Orthopedics 2023年第4期13卷 157-167页

作者： chunteng Theophile Nana Tsiagadigui Tsiagadigui Jean Gustave Ngo Yamben Marie-Ange Batchom Daudet Bombah Freddy Muluem Kenedy Mokake Divine Ngomba Ekani Boukar Mahamat Ali Mahamat Takou Bougoue Andre Gaetan simo Wambo Tagakou Mboula christian Fotso Ndasi Henry Pius Fokam Department of Surgery Faculty of Health Sciences University of Buea Buea Cameroon Department of Surgery and Specialties Faculty of Medicine and Biomedical Sciences University of Yaounde 1 Yaounde Cameroon Department of Surgery and Specialties Faculty of Medicine and Pharmaceutical Sciences University of Douala Douala Cameroon

Background: Pelvic fractures constitute about 2% - 8% of all fractures. This incidence may rise up to 25% in poly-traumatised patients. These fractures have a high mortality rate due to the fact that they occur usually as a result of high energy trauma, and most of the injured are poly-traumatised with concomitant haemodynamic instability. The aim of this study is to describe the patterns of injury and complications of unstable pelvic fractures treated in a level III hospital in cameroon. Methodology: This was a hospital based retrospective analysis of files of patients admitted and treated for unstable pelvic fractures at the Regional Hospital Limbe within a period of 10 years (from 1st of January 2009 to 31st of December 2018). Results: A total of 139 cases of pelvic fractures were identified, amongst which 77 were unstable;68 were finally analyzed. The ages ranged from 18 to 80 years with a mean of 39 ± 5 years. The age group from 20 - 40 years was most represented (58.88%, n = 40). There were 45 males and 23 females giving a sex-ratio of 2:1. Road traffic injuries accounted for most of the cases (73.53%, n = 50). Forty-five (66.2%) were classified Tile B and 23 (33.82%) were Tile c, and 15 cases were open fractures (22.06%). Associated lesions were recorded in 30 cases, fractures of the lower extremity being the most common (33.33%, n = 10). Most of the cases were definitively treated surgically (80.89%, n = 55). The most common complications were surgical site infections (23.64%, n = 13). conclusion: Unstable pelvic fractures are relatively common. Young males in the age group 20 - 40 years are the most affected, and the most common cause of injury was road traffic accident. Surgical site infections, pressure ulcers, severe anaemia and thrombo-embolism are common complications.

关键词： Unstable Pelvic Fracture Patterns complications cameroon

Radical Hysterectomy in cervical cancer: Patients’ Epidemiological and clinical Profiles and Perioperative Outcome in Two Referral Hospitals in cameroon

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Open Journal of Obstetrics and Gynecology 2024年第3期14卷 466-479页

作者： Théophile Njamen Nana Robert Tchounzou Fulbert Nkwele Mangala Alphonse Ngalame Henri Essome Sedrick Tiokeng Sidonie Noa Ananga Andrew Tassang Humphry Tatah Neng Isaac Mboh Eyong Gaetan Andre Wambo simo Felix Adolphe Elong Fidelia Kobenge Mbi Junior cédric Nana Njamen charlotte Tchente Nguefack Thomas Obinchemti Egbe Gregory Ekane Halle Emile Telesphore Mboudou Marcellin Ngowe Ngowe Department of Obstetrics and Gynaecology Douala General Hospital Douala Cameroon Department of Obstetrics and Gynaecology Faculty of Health Sciences University of Buea Buea Cameroon Department of Obstetrics and Gynaecology Douala Gynaeco-Obstetric and Pediatric Hospital Douala Cameroon Department of Surgery and Specialties Faculty of Medicine and Pharmaceutical Sciences University of Douala Douala Cameroon Department of Pathology Douala General Hospital Douala Cameroon Faculté Des Sciences De La Santé Université Joseph Kizerbo Ouagadougou Burkina Faso

Background: cervical cancer (cc) is one of the most frequent cancers and the leading cause of death from gynecological cancer in Low and middle income countries, cameroon inclusive. Surgery is the primary treatment modality when the disease is diagnosed at early stage. Radical hysterectomy in cervical cancer has not been evaluated in recent years in cameroon. The purpose of this study is thus to evaluate the epidemiological and clinical features and short term outcomes of patients who underwent surgery. Patients and methods: This retrospective study was conducted at the Douala Gynaeco-obstetric and Pediatric Hospital and the Douala General Hospital. cervical cancer patients who underwent Radical hysterectomy between January 2015 and December 2020 were included. A pre-established data collection tool was used to record socio-demographic, clinical and outcomes information from patients’ files;additional outcome information was obtained from phone calls. Descriptive analysis was done using the SPSS version 26. Bivariate analysis was used to determine associations between disease and patients characteristics and occurrence of adverse postoperative outcome. P value of 0.05 was considered. Results: Sixty one patients were enrolled. Their ages ranged from 33 to 74 years with a mean age of 51.95 ± 10.29 years. Over 85% of women were married, 65.57% were unemployed and 86.88% were multiparous. Only 28% had never done cervical cancer screening. Most patients had stage IB1 to IB2 stage disease (57.1%). Less than 9% underwent radical hysterectomy and 8 of those (13.11%) suffered intraoperative complications. Twenty-five patients (40.98%) presented immediate and short term complications. There was no significant association between the disease or patients’ characteristics and adverse outcomes. conclusion: cervical cancer patients are relatively young in our settings and only 9% of them reach the hospital at early stage. Postoperative adverse outcomes rate is higher than that rep

关键词： cervical cancer Radical Hysterectomy Epidemiological and clinical Profiles Outcomes cameroon

Biological Markers of Undernutrition and Risk of complications in children Hospitalized at the Teaching Hospital of Brazzaville

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Biosciences and Medicines 2022年第2期10卷 1-9页

作者： christel Mikolélé-Bilombo Lucie charlotte Atipo-Ibara Ollandzobo Steve Vassili Missambou Mandilou Thibaut Ocko Gokaba Lethso clausina Mikolélé-Bilomb Ahoui Josué simo Louokdom Martial Landry Miguel Etienne Mokondjimobe Donatien Moukassa Jean Robert Mabiala-Babela Ange Antoine Abena Jean-Rosaire Ibara Faculty of Health Sciences Marien Ngouabi University Brazzaville Congo Department of Pediatrics Teaching Hospital of Brazzaville Brazzaville Congo Department of Gastroenterology and Hepatology Teaching Hospital of Brazzaville Brazzaville Congo cameroon Mountain University Douala Cameroon Denis Sassou Nguesso University Brazzaville Congo

Introduction: Undernutrition is a condition frequently encountered in pediatrics. It leads to an increased morbidity and mortality regardless of the underlying condition or other risk factors such as age. In countries with limited resources such as ours, the diagnosis of undernutrition is often limited to the clinical presentation, and the contribution of biology is not often taken into account. Objectives: To establish the relationship between anthropometric parameters and biological markers in the diagnosis and classification of undernutrition and to assess the risk of infectious complications during undernutrition in children. Materials and Methods: A cross-sectional study conducted in Brazzaville among undernourished children aged 1 - 59 months between October 2018 and April 2019. clinical diagnosis was based on WHO growth charts. The cRP, orosomucoid, albumin and transthyretin were obtained using the cobas c311 analyzer, which enabled the calculation of Prognostic Inflammatory and Nutritional Index (PINI). The comparison of the means of the biological markers used the Student’s t-test, the risk of infectious complications the chi-square. The correlation of the diagnostic value of Z-score weight/height and PINI was also investigated. The significance level was set at 0.05. Results: Of the 95 children enrolled 63 (66.3%) were clinically severely malnourished, including 26 acute (41.3%) and 37 chronic (58.7%). The PINI revealed severe undernutrition in 85 children (89.4%) including 50 acute (58.8%) and 35 chronic (41.2%). cRP and orosomucoid were statistically higher in severe acute undernutrition (p conclusion: Anthropometric parameters have a front-line advantage for assessing and classifying undernutrition. However, biological markers of undernutrition with PINI should be systematized in the diagnosis and management of undernutrition.

关键词： Undernutrition Nutritional Marker Inflammatory Marker PINI child congo

2型糖尿病患者皮下脂肪面积与空腹c肽水平的相关性研究

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

中国医药导报 2020年第18期17卷 76-80,86页

作者：刘思默柯静安雅欣赵冬首都医科大学附属北京潞河医院内分泌代谢与免疫性疾病中心北京101149

目的探讨2型糖尿病患者空腹c肽水平与皮下脂肪面积变化的特点及相关性。方法纳入2017年10月~2019年11月首都医科大学附属北京潞河医院内分泌代谢与免疫性疾病中心住院的1461例2型糖尿病患者,根据皮下脂肪面积将其分为三组,即T1组 0.05)... 详细信息

目的探讨2型糖尿病患者空腹c肽水平与皮下脂肪面积变化的特点及相关性。方法纳入2017年10月~2019年11月首都医科大学附属北京潞河医院内分泌代谢与免疫性疾病中心住院的1461例2型糖尿病患者,根据皮下脂肪面积将其分为三组,即T1组cm^2,173.5 cm^2≤T2组cm^2,T3组≥223.5 cm^2。T1组506例,T2组482例,T3组473例。比较三组间身高、体重、腰围、空腹c肽水平等各临床指标。采用相关分析分析空腹c肽水平与体脂及代谢指标的相关性,并运用多元回归模型分析空腹c肽水平的独立影响因素。结果三组性别、糖化血红蛋白、空腹血糖、总胆固醇、低密度脂蛋白胆固醇水平以及估算的肾小球滤过率指标比较,差异无统计学意义(P> 0.05)。与T2组比较,T3组患者的年龄偏小,差异有统计学意义(P 0.05)。与T1组比较,T2组和T3组体重指数、腰围、内脏脂肪面积、舒张压、尿酸指标升高,且T3组高于T2组,差异均有统计学意义(P c肽水平比较,差异有统计学意义(P c肽水平呈正相关(r=0.35,P c肽水平仍呈独立正相关(B=0.00,β=0.16,P c肽水平升高,二者呈独立正相关。

关键词： 2型糖尿病肥胖皮下脂肪面积空腹c肽水平

在线全文

学校读者我要写书评

暂无评论

老年食管癌患者列线图预后模型的构建与验证

中国现代医药杂志 2023年第3期25卷 10-17页

作者：何珂瑶张家豪陈斯默张耀文周福有安阳市肿瘤医院胸外科河南省食管癌精准防治医学重点实验室河南安阳455000 安阳市肿瘤医院放疗科河南安阳455000

目的构建老年食管癌(Ec)患者总生存率(OS)列线图预测模型,并进行内部验证。方法回顾性分析2000~2018年SEER数据库中老年Ec患者的临床病理资料及随访信息。采用cox及最小化绝对收缩和选择算子(LASSO)回归分析筛选预后危险因素,纳入危险... 详细信息

目的构建老年食管癌(Ec)患者总生存率(OS)列线图预测模型,并进行内部验证。方法回顾性分析2000~2018年SEER数据库中老年Ec患者的临床病理资料及随访信息。采用cox及最小化绝对收缩和选择算子(LASSO)回归分析筛选预后危险因素,纳入危险因素构建预测老年Ec患者OS的列线图。使用一致性指数(c-index)、受试者工作特征(ROc)曲线及校准曲线评估列线图的预测精准度;决策曲线分析衡量列线图的临床应用价值。通过KaplanMeier生存分析比较各OS独立危险因素与患者生存时间的相关性。结果共纳入6311例老年Ec患者,年龄、病理分级、T分期、N分期、M分期、手术和化疗是其OS的独立危险因素(Pc-index为0.717[95%cI(0.709~0.725)],1年、3年及5年ROc曲线下面积分别为0.786、0.811及0.813;验证组列线图的c-index为0.723[95%cI(0.709~0.737)],1年、3年及5年ROc曲线下面积分别为0.793、0.818及0.815,同时校准曲线显示列线图预测患者OS与临床实际OS具有高度一致性。决策曲线分析表明该列线图具有临床适用性。生存分析提示年龄大、病理分化程度低、肿瘤浸润程度深、淋巴结转移率高及伴有远处转移的患者预后更差,而行Ec切除术或化疗的患者其OS显著高于未行Ec切除术或化疗的患者(Pc患者1年、3年及5年OS的列线图,并验证了该列线图的准确性,有助于临床医师有效评估患者预后,提供最佳治疗策略。

关键词：食管癌老年列线图预后模型