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A Study into Digital Dermatitis Transmission and Bacterial Associated Pathological Changes Involved in the Disease

Open Journal of Veterinary Medicine 2013年第2期3卷 192-198页

作者： N.Capion M.boye C.Ekstrom K.Dupont T.K.Jensen Department of Large Animal Sciences Faculty of Health and Medical SciencesUniversity of CopenhagenCopenhagenDenmark National Veterinary Institute Technical University of DenmarkCopenhagenDenmark Department of Biostatistics University of Southern DenmarkOdenseDenmark

Digital dermatitis is a highly prevalent painful lesion affecting the feet in dairy cattle. Even though the pathogenesis has been subject of investigation since 1974, there is still a lack of knowledge about the spread of the disease among cows within a herd as well as between herds. The purpose of this study was to monitor transmission of digital dermatitis under experimental conditions between naive heifers and affected animals, to monitor the changes in clinical appearance, microbial colonisation of the skin as lesions progressed and to apply a q-PCR for the detection of Treponema spp. in faecal samples. Eight heifers with clinical normal digital skin were housed with 5 heifers with severe digital dermatitis lesion for 8 weeks on a solid concrete floor with an accumulating layer of slurry. Digital skin was examined daily and lesions were clinically scored. Skin biopsies were taken from the healthy heifers at introduction and weekly from all lesions for histopathological evaluation and fluorescence in situ hybridization. None of the healthy heifers developed digital dermatitis and in 4 out of 5 infected heifers the lesions healed during the study. All samples from healthy skin were negative for Treponema spp. and one sample were positive for Dichelobacter nodosus. Colonization of healthy skin could not be identified in this study. There was no significant relation between clinical scoring of the lesions and histopathological score and the presence of Treponema spp. There were however a significant relation between the prevalence of Treponema spp. in the skin and severity of changes in epidermis and dermis. By qPCR all the healthy heifers were found to excrete Treponema spp. in their faeces.

关键词： Digital Dermatitis Treponema spp. Histopathology Infection Dynamics

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胰腺癌

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国外学者来访报告 1989年第1期9卷 19-22页

作者： boye.,TO 周怡和

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碱性盐在生鲜湿面保鲜和品质调控中的应用

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食品科学 2022年第16期43卷 26-35页

作者：田宇刘伯业陈复生曹涵河南工业大学粮油食品学院河南郑州450001

为深入探讨碱性盐对生鲜湿面保质期和品质特性的影响,选用不同添加量的5种碱性盐(碳酸钠、碳酸钾、磷酸三钠、磷酸三钾及碳酸氢钠)制作生鲜面条,通过将菌落总数、L^(*)值和表观状态作为表征生鲜湿面变质的可视化参数,确定不同碱性盐在... 详细信息

为深入探讨碱性盐对生鲜湿面保质期和品质特性的影响,选用不同添加量的5种碱性盐(碳酸钠、碳酸钾、磷酸三钠、磷酸三钾及碳酸氢钠)制作生鲜面条,通过将菌落总数、L^(*)值和表观状态作为表征生鲜湿面变质的可视化参数,确定不同碱性盐在生鲜湿面中的最适添加量;通过测定贮藏期间生鲜湿面pH值、面团流变学特性、面条烹饪特性和质构特性、感官评价并用扫描电镜观察微观结构综合分析碱性盐对生鲜湿面品质的影响规律。结果表明:与对照组相比,碱性盐添加可有效抑制生鲜湿面中微生物的生长,添加2.0%的碳酸钠,能够将生鲜湿面保质期延长2.5倍,碱性盐均使面条呈现明亮的浅黄色外观,明显改善其表观状态,确定碳酸钠在生鲜湿面中最适添加量为1.0%,其余4种碱性盐最适添加水平均为1.5%。在贮藏期间,添加碱性盐调控且稳定面条pH值,显著增强面团吸水率和拉伸特性、降低面团弱化度,且延伸度随着醒发时间的延长而降低;增加了生鲜湿面蒸煮损失,降低面条吸水率、提高硬度、拉伸强度、弹性、黏性和适口性。扫描电镜发现,碱性盐的添加能够加强生鲜湿面中蛋白质和淀粉的交联程度,从而形成更加连续致密的面筋网络结构。其中碳酸钠对生鲜湿面品质改善效果最为突出。

关键词：碱性盐生鲜湿面保鲜效果品质调控

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Cardiac Echography in Pediatrics at the Regional Hospital of Diourbel: Indication and Result

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World Journal of Cardiovascular Diseases 2023年第9期13卷 556-564页

作者： Aliou Mar Coundoul Abdou Aziz Faye Khadim Bop Amadou Lamine Fall Papa Moctar Faye Ndeye Fatou boye Ndeye Tenning Faye Ousmane Ndiaye Pediatric Service Cheikh Ahmadoul Khadim National Hospital Center of Touba Diourbel Diourbel Senegal Albert Royer National Hospital Center Dakar Senegal Henrich Lû ckbe Center Diourbel Senegal

Childhood heart disease is a real public health problem. In our contexts, care remains a major challenge. Doppler echocardiography remains the essential examination for diagnosis. The objective of our study was to describe the different clinical indications for cardiac ultrasound in children and the main pediatric heart diseases at the Diourbel Heinrich Lübke Regional Hospital. This was a descriptive and analytical retrospective study spanning from 2020 to 2022;covering a series of 140 cases. The study was carried out using patient clinical observation sheets and consultation sheets. We identified 140 ultrasounds. The average age of patients was 35.96 months with extremes of 0.03 months and 192 months. The female sex was predominant, with an M/F sex ratio of 0.72. Ultrasound was systematically requested in 67.14% of the study population. The indications found were mainly: heart murmur, polymalformative syndrome, respiratory failure, bronchiolitis, cardiomegaly, suspicion of heart disease, cardiomegaly, pre-therapeutic and pre-operative assessment. A total of 71 cardiac abnormalities were found in 65 patients, i.e. a prevalence of 46.42%. Congenital heart disease was more frequent (found in 49 patients, a prevalence of 35%) and was dominated by the CIA. There was a female predominance in almost all heart diseases except in the case of endocarditis where codominance is found. Our study has made it possible, through echocardiography, to evaluate the indications for echocardiography in children, to determine the prevalence of heart disease in children and also to assess the relevance of requests for echocardiography.

关键词： Echocardiography Pediatrics Indications Diourbel

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How do Patients with Schizophrenia Perceive Relatives’ Levels of Expressed Emotions? A Brief Patient Rated Scale

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Open Journal of Psychiatry 2017年第3期7卷 220-234页

作者： Heidi Bjø rge Tor Helge Notland Turid Birgitte boye Ingun Dina Ulstein Nina Aarhus Smeby Ulrik Fredrik Malt Hå vard Bentsen Oslo and Akershus University College of Applied science Faculty of Health Institute of Nursing and Health Promotion Oslo Norway Institute of Clinical Medicine Faculty of Medicine University of Oslo Oslo Norway Blakstad Hospital Asker Norway Section of Psycho-oncology Oslo University Hospital Oslo Norway Institute of Basic Medical Sciences Faculty of Medicine University of Oslo Oslo Norway Department of Psychiatry of Old Age Oslo University Hospital Oslo Norway Department of Research Division of Mental Health and Dependence Oslo University Hospital Oslo Norway Department of Research and Education Division of Surgery and Clinical Neuroscience Oslo University Hospital Oslo Norway Center for Psychopharmacology Diakonhjemmet Hospital Oslo Norway

Background : Patients’ perspective on relatives’ attitude and behaviour towards them (Expressed emotion—EE) may be an important addition to the current focus on relatives’ perspective only, as measured by Camberwell Family Interview (CFI) or other methods. Based on the theory of EE, we have designed a brief, three-item questionnaire completed by patients, named Felt Expressed Emotion Rating Scale (FEERS). FEERS measures the patient’s experience of criticism (Cri) and emotional over involvement (i.e. worry (Wo), and control (Con). Aims: To investigate the test-retest reliability of the FEERS and associations between the FEERS and the CFI and to which extent FEERS scores were modified by severity of psychotic symptoms, cognitive function, patient mood and amount of face-to-face contact with relatives. Methods : Forty-five patients with schizophrenia and related psychoses admitted to a psychiatric hospital and 67 relatives were included. Assessments included FEERS, CFI and Positive and Negative Syndrome Scale (PANSS). Results : FEERS-Cri test-retest intra-class correlation (ICC1,1) was 0.71 among patients with low total PANSS scores, low cognitive impairment (0.59) and depression (0.63). For low levels of cognitive impairment, the ICCs of the FEERS-Wo and the FEERS-Con were 0.62 and 0.83, respectively. The FEERS-Cri and FEERSHowWo correlated significantly with CFI-CC and CFI-positive comments, respectively. Among the relatives that the patient deemed “not at all critical” (low FEERS-Cri scores), 94% had low CFI-CC levels. Conclusions : The FEERS may be a brief, time-saving alternative for identifying relatives with low levels of criticism. However, illness severity, cognitive function and mood influence FEERS test-retest reliability and link to CFI.

关键词： Expressed Emotion Perceived Criticism Schizophrenia Validity

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数字经济、融资约束与企业创新质量——来自高新技术上市公司的经验证据

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财经理论与实践 2024年第6期45卷 76-84页

作者：刘照德彭博烨沈倩广东财经大学经济学院广东广州510320

依据2016—2022年中国数字经济数据与高新技术上市公司数据,运用固定效应模型,基于融资约束中介效应视角,考量数字经济对高新技术企业创新质量的影响。结果显示:中国各省(区、市)数字经济发展不平衡,总体发展空间较大;数字经济促进高新... 详细信息

依据2016—2022年中国数字经济数据与高新技术上市公司数据,运用固定效应模型,基于融资约束中介效应视角,考量数字经济对高新技术企业创新质量的影响。结果显示:中国各省(区、市)数字经济发展不平衡,总体发展空间较大;数字经济促进高新技术企业创新产出效果显著,尤其是实质性创新。融资约束存在部分中介效应,对实质性创新影响显著,但对非实质性创新的影响不显著;相较于非国有企业和东部地区企业,数字经济发展对国有企业和中西部地区企业创新质量的正向影响更大。

关键词：数字经济创新质量融资约束

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研究型大学:国际合作与大学发展(英文)

研究型大学:国际合作与大学发展(英文)

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北京论坛（2008）文明的和谐与共同繁荣——文明的普遍价值和发展趋向

作者： Abdou Salam Sall Cheikh Saad Bouh boye Cheikh Anta Diop University

I would like to thank our Chinese colleagues for their invitation and I would like to extend my thanks to the Public Intemational University *** can I say about research,intemational cooperation and university development that you don’t already know?We are in a world based on knowledge and now all recognize the place and role of higher education not only for developed countries but also for developing *** World Bank recognized it recently and the United States of America is currently preparing a big initiative for High Education in developing countries,mainly in *** clearly said that they wish to develop the Higher Education for business *** world conference for higher education has been clear about those orientations since 1998.

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基于IS-LM-PC模型的浙江省三大需求和两大指标分析

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浙江树人大学学报 2019年第2期19卷 59-66页

作者：杨博野浙江省发展和改革研究所浙江杭州310025

基于最新的IS-LM-PC模型,对浙江投资、消费、出口三大需求和地区生产总值、物价两大指标发生趋势性变化的原因及其影响因素进行分析,发现浙江经济需求侧和供给侧分别受到企业预期、房地产市场、金融市场、外汇市场、外贸市场、税收政策... 详细信息

基于最新的IS-LM-PC模型,对浙江投资、消费、出口三大需求和地区生产总值、物价两大指标发生趋势性变化的原因及其影响因素进行分析,发现浙江经济需求侧和供给侧分别受到企业预期、房地产市场、金融市场、外汇市场、外贸市场、税收政策和供给侧结构性改革等不同外生变量冲击,预期影响和政策叠加效应明显。建议政府既要平衡好稳增长与防风险、长期目标与短期目标的关系,把握好政策实施节奏和力度,也要加强市场对于政策的反应分析,做好政策出台对市场的叠加效应评估,善于引导预期。

关键词：宏观经济学浙江经济 IS-LM模型 PC模型供给侧需求侧

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欧登赛──世界童话之都

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技术经济与管理研究 1998年第4期 13-13页

作者： Anker boye

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Chemical Variability and Antibacterial Activity of Eucalyptus camaldulensis Essential Oils from Senegal

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International Journal of Organic Chemistry 2022年第4期12卷 173-180页

作者： Yoro Tine Alioune Diallo Idrissa Ndoye Cheikhouna Gaye Benjamin Ndiaye Abdoulaye Diop Jean Costa Cheikh Saad Bouh boye Alassane Wélé Julien Paolini Laboratoire de Chimie Organique et Thérapeutique Faculté de Médecine Pharmacie et Odontologie Université Cheikh Anta Diop Dakar Senegal Université de Corse UMR CNRS 6134 SPE Laboratoire de Chimie des Produits Naturels Campus Grimaldi Corte France Laboratoire de Bactériologie-virologie H&ocirc pital Aristide Le Dantec Dakar Senegal

1,8-cineole, also known as eucalyptol, is the main constituent and the most important of the leaf oils of many species of the genus Eucalyptus. In present study, the essential oils isolated by hydrodistillation from the leaves of Eucalyptus camaldulensis from six different locations were analyzed by GC-FID and GC-MS. Essential oil yields ranged from 0.33% to 4.35%. In total, 34 constituents were identified, accounting for 94.0% to 99.8% of the total compositions. 1,8-cineole (46.4% - 84.4%) was the main constituent of all the essential oil samples, except for one sample collected in the Fatick region, which had p-cymene (46.4%) and 1,8-cineole (26.0%) as major compounds. The essential oil showed excellent activity against S. aureus, E. coli and E. faecalis (IZ = 25.3 ± 1.2 mm;18.7 ± 0.6 mm;17.8 ± 0.3 mm, respectively) and moderate activity against P. aeruginosa (IZ = 10.8 ± 0.8 mm). They may have potential applications in food and pharmaceutical products.

关键词： Eucalyptus camaldulensis Essential Oils Antibacterial Activity 1 8-Cineole and GC-SM

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