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Simulations of helicopter ditching using smoothed particle hydrodynamics

Journal of Hydrodynamics 2020年第4期32卷 653-663页

作者： G.Oger A.Vergnaud B.Bouscasse J.Ohana M.Abu Zarim M.De Leffe a.bannier L.Chiron Y.Jus M.Gamier S.Halbout D.Le Touze Ecole Centrale de Nantes LHEE4 Laboratory(ECN and CNRS)NantesFrance Nextflow Software NantesFrance Bureau Veritas Solutions Marine and Offshore NantesFrance Airbus Helicopters MarseilleFrance

The present work has been performed in the context of the European H2020 project increased SAfety and Robust certification for ditching of Aircrafts and Helicopters(SARAH)dedicated to improving the safety during aircraft ditching,together with a better understanding of the physics involved during those crucial *** numerical and experimental aspects are explored during this *** present study focuses on the application of the smoothed particle hydrodynamics(SPH)method to the simulation of helicopter ditching,as this method has proved to be particularly adapted to free surface impact *** are performed for three different impact configurations,for which the numerical solutions are compared with the experimental results(forces and kinematics)obtained at the wave basin of Ecole Centrale Nantes on a mock-up shape provided by Airbus *** of sensitivity analysis are also provided when needed,to assess the role of some parameters involved in the helicopter behavior and the fluid pressure forces exerted during the impact.

关键词： Helicopter ditching smoothed particle hydrodynamics(SPH) Free surface impact wave impact numerical vs experimental solutions

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Locoregional treatment of early breast cancer with isolated tumor cells or micrometastases on sentinel lymph node biopsy

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World Journal of Clinical Oncology 2016年第2期7卷 243-252页

作者： Agnès Tallet Eric Lambaudie Monique Cohen Mathieu Minsat Marie bannier Michel Resbeut Gilles Houvenaeghel Departement of Radiotherapy Institut Paoli Calmettes and CRCM Departement of Surgery Institut Paoli Calmettes and CRCM Aix Marseille Université Jardin du Pharo

The advent of sentinel lymph-node technique has led to a shift in lymph-node staging,due to the emergence of new entities namely micrometastases(p N1mi) and isolated tumor cells [p N0(i+)].The prognostic significance of this low positivity in axillary lymph nodes is currently debated,as is,therefore its *** article provides updates evidence-based medicine data to take into account for treatment decision-making in this setting,discussing the locoregional treatment in p N0(i+) and p N1 mi patients(completion axillary dissection,axillary irradiation with or without regional nodes irradiation,or observation),according to systemic treatment,with the goal to help physicians in their daily practice.

关键词： Breast cancer Micrometastases Axillary lymph node dissection Radiotherapy Isolated tumor cells

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Is breast conservative surgery a reasonable option in multifocal or multicentric tumors?

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World Journal of Clinical Oncology 2016年第2期7卷 234-242页

作者： Gilles Houvenaeghel Agnès Tallet Aurélie Jalaguier-Coudray Monique Cohen Marie bannier Camille Jauffret-Fara Eric Lambaudie Institut Paoli Calmettes and CRCM Aix Marseille Université

The incidence of multifocal(MF) and multicentric(MC) carcinomas varies widely among clinical studies,depending on definitions and methods for pathological *** resonance imaging is increasingly used because it can help identify additional and conventionally occult tumors with high ***,false positive lesions might incorrectly influence treatment ***,preoperative biopsies must be performed to avoid unnecessary *** studies have shown higher lymph node involvement rates in MF/MC tumors than in unifocal ***,the rate of local recurrences is usually low after breast conservative treatment(BCT) of MC/MF *** has been suggested that BCT is a reasonable option for MC/MF tumors in women aged 50-69 years,with small tumors and absence of extensive ductal carcinoma in situ.A metaanalysis showed an apparent decreased overall survival in MC/MF tumors but data are *** should achieve both acceptable cosmetic results and negative margins,which requires thorough preoperative radiological workup and localization of *** radiotherapy techniques must be evaluated since double boosts might result in increased toxicity,namely *** conclusion,BCT is feasible in selected patients with MC/MF but the choice of surgery must be discussed in a multidisciplinary team comprising at least radiologists,surgeons and radiotherapists.

关键词： Mastectomy Breast conservative surgery Multifocal tumors Multicentric tumors Radiotherapy Local recurrence Breast cancer Survival

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3.0T MR无创性检测肝脏铁含量:活检验证

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国际医学放射学杂志 2018年第4期 489-490页

作者： G.d'Assignies A.Paisant E.Bardou-Jacquet A.Boulic E.bannier F.Lainé 陈圣妮 Department of Radiology Rennes University Hospital

目的采用3 T MRI评估R2*值和信号强度比（SIR）方法定量检测肝脏铁含量（LIC）的效能及局限性。方法这项前瞻性研究共纳入105例病人,行肝脏活检测量组织生化铁含量（LICb）。所有病人均进行3 T MRI屏气多回波梯度回波（mGRE）序列扫描... 详细信息

目的采用3 T MRI评估R2*值和信号强度比（SIR）方法定量检测肝脏铁含量（LIC）的效能及局限性。方法这项前瞻性研究共纳入105例病人,行肝脏活检测量组织生化铁含量（LICb）。所有病人均进行3 T MRI屏气多回波梯度回波（mGRE）序列扫描。通过3 T SIR算法(LICSIR)和R2*（LICR2*）计算出LIC,并与LICb行相关分析。将数据等分为连续多组对2种方法的比较。结果LICb与R2*（r=0.95,P130μmol/g时,LICSIR差异性最低。结论 3 T MRI R2*在铁过载水平较低时可精确定量LIC,但铁过载水平较高时建议使用SIR方法克服R2*的局限性。该软件发布在***网站,可综合应用2种方法 ,并择优使用。

关键词： MRI 铁含量 MR LIC

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