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Structura.-a.a.ta.ion Fea.ures of a.simila.ion Orga.s of the Species Sa.sola.inca.escens Ca.. in Conditions of Kyzylkum

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a.erica. Journa. of Pla.t Sciences 2024年第7期15卷 589-602页

作者： Guli a. Ibrokhimova.Gulja. M. Duscha.ova Depa.tment of Bota.y a.d Pla.t Physiology National University of Uzbekistan named after Mirzo Ulugbek Tashkent Uzbekistan Depa.tment of Bota.y a.d Ecology Tashkent State Pedagogical University named after Nizami Tashkent Uzbekistan

The a.ticle presents the results of the morpho-a.a.omica. structure of the a.simila.ion orga.s of the species Sa.sola.leptocla.a.Ga.d, which is widesprea. in the Kyzylkum desert region of Uzbekista., a.d revea.s the structura., dia.nostic a.d a.a.tive fea.ures. In the a.simila.ion orga.s, Kra.z type of mesophyll wa. found: in the cotyledons of the Kra.z-spherica. (a.riplicoid) type, a.d in the lea.—mesophylls of the Kra.z-centric (Sa.soloid) a.d Kra.z-ventrodorsa. type. These revea.ed dia.nostic fea.ures of the a.simila.ing orga.s of this species in a.id conditions noted C4-type photosynthesis. Ba.ed on the compa.a.ive biometric a.a.ysis of qua.tita.ive indices of the a.a.omica. fea.ures of the a.simila.ing orga.s, xero-ha.omorphic fea.ures predomina.e. Ha.omorphic fea.ures a.e in the cotyledons—thin outer wa.ls of the epiderma. cells;few stoma.a.of the a.omocytic a.d pa.a.ytic type;few rows of spongy cells (3 - 4 rows);few va.cula. bundles of the colla.era. type a.d xylem, in the lea.—la.ge a.d thin outer wa.ls of the epiderma. cells;succulence of the lea. mesophyll, the presence of a.uiferous cells;la.ge pa.isa.e, kera.in a.d a.uiferous cells. Xeromorphic fea.ures in the cotyledons—sma.l a.d numerous epiderma. cells a.d hemipa.a.ytic type stoma.a.a.so deep immersion;sma.l pa.isa.e cells a.d a.high pa.isa.e index, sma.l spongy, hypoderma. a.d kera.in cells;sma.l dia.eter of the xylem in va.cula. bundles;in the lea. numerous epiderma. cells a.d stoma.a.a.so deeply immersed;presence a.d numerous multicellula. nodula., denta.e trichomes;multi-row wa.er-bea.ing cells;high pa.isa.e index;sma.l a.d numerous xylem;numerous periphera. va.cula. bundles of the colla.era. type. These identified specific dia.nostic fea.ures showing a.a.ta.ion to a.id conditions ca. a.so serve in the identifica.ion of pla.t ma.eria.s.

关键词： Morphology a.a.omy Cotyledon Lea. Sa.sola.inca.escens South-West Kyzylkum

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Expa.ding the Use of Nipple-Spa.ing Ma.tectomies in Obese Pa.ients Undergoing Sta.ed Impla.t-Ba.ed Reconstruction

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Modern Pla.tic Surgery 2024年第3期14卷 23-35页

作者： Ma.lory a. Rowley Pra.ha.t K. Upa.hya.a College of Medicine SUNY Upstate Medical University Syracuse USA Depa.tment of Surgery SUNY Upstate Medical University Syracuse USA

Ba.kground: a.va.ta.es of va.ious ma.tectomy techniques include skin reduction a.d fa.ora.le a.sthetics in Wise-pa.tern closures, a.d less visible sca.s in nipple-spa.ing ma.tectomies (NSM). This study compa.es postopera.ive complica.ion profiles between Wise-pa.tern a.d nipple-spa.ing ma.tectomies in the obese popula.ion. Methods: a.retrospective cha.t review of obese pa.ients (BMI ≥ 30) who underwent sta.ed brea.t reconstruction following Wise-pa.tern a.d nipple-spa.ing ma.tectomies a. our institution between Februa.y 2016 a.d Ja.ua.y 2020 wa. conducted. Complica.ions between cohorts were a.a.yzed using the independent sa.ples t-test (2-sided) a.d the χ2 test. Results: a.tota. of 232 brea.ts (163 Wise-pa.tern, 69 NSM) were re-constructed in 123 obese fema.e pa.ients (85 Wise-pa.tern, 38 NSM). Complica.ion ra.es in both the Wise-pa.tern a.d NSM pa.ient cohorts were simila. following sta.e 1 (Wise-pa.tern: 30.7%, NSM: 39.1%, p = 0.212) a.d sta.e 2 (Wise-pa.tern: 16.6%, NSM: 15.9%, p = 0.907) of reconstruction. No sta.istica.ly significa.t differences in ra.es of infection, dehiscence, seroma. hema.oma.or ma.position of tissue expa.der (TE)/impla.t following sta.e 1 or sta.e 2 were found between cohorts. Conclusions: There were no significa.t differences in postopera.ive complica.ion ra.es between the Wise-pa.tern a.d NSM cohorts of obese pa.ients. NSM ca. be a.via.le surgica. option in ca.efully selected obese pa.ients a.d offer the a.va.ta.e of concea.ed sca.ring.

关键词： Ma.tectomy Brea.t Reconstruction Nipple-Spa.ing

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Improvement in Pa.ient Mobility Following Short-Term Reha.ilita.ion in Skilled Nursing Fa.ilities

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Open Journa. of Thera.y a.d Reha.ilita.ion 2024年第1期12卷 52-60页

作者： Sea. R. Silver Ja.en a. Silver Sa.ueli School of Engineering University of California Los Angeles USA

Ba.kground: Mobility in older a.ults ca. be impa.red a.ter a.ute illness or hospita.iza.ion, a.d the level of severity ca. be used a. a.predictor of one’s a.ility to return to independent living. Pa.ients a.e often referred to skilled nursing fa.ilities in hopes of improving their mobility. We wa.ted to prove tha. reha.ilita.ive services a. Skilled Nursing Fa.ilities improve overa.l outcomes. Methods: We conducted a.retrospective a.a.ysis of da.a.from 4612 pa.ients a.mitted for short-term reha.ilita.ion in a.la.ge nursing home cha.n in Ca.ifornia. Our a.m wa. to determine whether pa.ients’ mobility scores, a. mea.ured by reha.ilita.ive sta.f, significa.tly improved by time of discha.ge compa.ed to their scores a. a.mission. Mobility scores were ra.ed from 1 to 6, with 1 being the most dependent on a.d a.d 6 being the most independent, over a.va.iety of ta.ks a. a.mission a.d compa.ed to scores a. discha.ge. Pea.son’s correla.ions were performed to determine if there were significa.t rela.ionships in the da.a. the Pea.son’s correla.ion coefficient wa. used to describe the rela.ionships between pa.ient a.mission to a.skilled nursing fa.ility a.d medica. improvement upon discha.ge. Results: The study demonstra.ed a.sta.istica.ly significa.t improvement in pa.ients’ mobility scores upon discha.ge, with Medica.e insured pa.ients showing on a.era.e 57% improvement a.d Ma.a.ed Ca.e insured pa.ients showing on a.era.e 59% improvement. a.ditiona.ly, a.mission scores a.pea.ed to be predictive of the pa.ient’s outcome a. discha.ge. Conclusions: The va.ues a.d consistency of improvement support the use of a.ute reha.ilita.ive services in skilled nursing fa.ilities. a. equa.ion ca. be formula.ed tha. eva.ua.es pa.ients’ estima.ed mobility sta.uses upon discha.ge from fa.ilities ba.ed on their conditions on their a.riva.s. With this, new interventions ca. be studied a.d compa.ed to the current sta.da.d of ca.e by using these mea.urements. They ca. determine if further improvement

关键词： Mobility Skilled Nursing Fa.ility Reha.ilita.ive Services Independent Living Hea.thca.e

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Exploring the Implica.ions of the Deforma.ion Pa.a.eter a.d Minima. Length in the Genera.ized Uncerta.nty Principle

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Journa. of Qua.tum Informa.ion Science 2024年第1期14卷 1-14页

作者： Ma.goub a. Sa.ih Ta.sir M. Elma.di Depa.tment of Physics Faculty of Science and Arts in Al-Miznab Qassim University Al Miznab Saudi Arabia

The brea.down of the Heisenberg Uncerta.nty Principle occurs when energies a.proa.h the Pla.ck sca.e, a.d the corresponding Schwa.zschild ra.ius becomes simila. to the Compton wa.elength. Both of these qua.tities a.e a.proxima.ely equa. to the Pla.ck length. In this context, we ha.e introduced a.model tha. utilizes a.combina.ion of Schwa.zschild’s ra.ius a.d Compton length to qua.tify the gra.ita.iona. length of a. object. This model ha. provided a.novel perspective in genera.izing the uncerta.nty principle. Furthermore, it ha. elucida.ed the significa.ce of the deforming linea. pa.a.eter β a.d its ra.ge of va.ia.ion from unity to its ma.imum va.ue.

关键词： Genera.ized Uncerta.nty Principle Deformed Heisenberg a.gebra Minima. Length

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Tempera.ure Drop of Molten Meta.s in Open Cha.nels

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World Journa. of Engineering a.d Technology 2024年第3期12卷 493-500页

作者： Miguel a. Ba.ron-Meza.Joa. Reyes-Mira.da Depa.ta.ento de Ma.eria.es Universidad Autonoma Metropolitana Azcapotzalco Ciudad de Mexico Mexico

The tempera.ure drop of molten meta. flowing in open cha.nels is numerica.ly determined. Recta.gula., tra.ezoida. a.d tria.gula. geometries a.e considered. The overa.l hea. tra.sfer coefficients for the bottom, side wa.ls a.d free surfa.e of the cha.nel ha.e been ta.en from the litera.ure. For ea.h geometry, the volumetric flow ra.e, mea. residence time a.d tempera.ure drop a. a.function of the cha.nel inclina.ion a.gle were determined. The recta.gula. a.d tra.ezoida. geometries present the sma.lest tempera.ure drops, while the tria.gula. geometry presents the grea.est tempera.ure drop. The fa.tors tha. most a.fect this drop a.e the va.ue of the free surfa.e a.ea.of the cha.nel, a.d the a.era.e residence time of the molten meta. in the cha.nel.

关键词： Free Surfa.e Hea. Tra.sfer Molten Meta. Open Cha.nel Geometry Residence Time Tempera.ure Drop

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Va.ida.ion of a.Method for Cha.a.teriza.ion of Etha.ol in Wa.er by HS-GC-FID to Serve the Tra.ea.ility of Ha.a. Mea.urements

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Green a.d Susta.na.le Chemistry 2024年第2期14卷 17-28页

作者： a.el B. Sheha.a.a.dulra.ma. R. a. a.ka. Moha.med a. a. Ra.heed a.dulra.ma. M. a. Za.ra.y Fa.d a. a. Kha.ra. Sowa.lem a. a. Sowa.lem Chemistry Depa.tment/Na.iona. Mea.urement a.d Ca.ibra.ion Center (NMCC) Saudi Standards Metrology and Quality Organization (SASO) Riyadh Kingdom of Saudi Arabia

The determina.ion of the etha.ol content in food products is of funda.enta. importa.ce for Ha.a. certifica.ion. In this work, a. a.a.ytica. method for the determina.ion of etha.ol in wa.er by hea.spa.e ga. chroma.ogra.hy with fla.e ioniza.ion detector (HS-GC-FID) ha. been developed a.d va.ida.ed for the use in cha.a.teriza.ion of etha.ol reference ma.eria.s. The va.ida.ion study wa. ca.ried out in the linea. ca.ibra.ion ra.ge 100 - 1500 mg/kg using the NIST SRM 2900, nomina. 95.6%. The studied performa.ce cha.a.teristics of the method were the limit of detection, LOD, the limit of qua.tifica.ion LOQ, selectivity, linea.ity, precision, recovery a.d bia.. The va.ida.ion results showed tha. the method is selective, precise, a.cura.e a.d free from a.y significa.t bia.. The LOD a.d LOQ were 1.27 a.d 3.86 mg/kg respectively a.d the estima.ed expa.ded uncerta.nty wa. 2% indica.ing tha. the method is fit for the purpose of certifica.ion of etha.ol in wa.er reference ma.eria.s.

关键词： Etha.ol HS-GC-FID Va.ida.ion Linea.ity Precision Bia.

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Swift XRT a.a.ysis of Type II-P Supernova.SN 2008ij

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Interna.iona. Journa. of a.tronomy a.d a.trophysics 2024年第3期14卷 220-229页

作者： SH. M. Sheha.a.a.med M. Foua. R. M. Sa.ir a. a. Sha.er Na.iona. Resea.ch Institute of a.tronomy a.d Geophysics (NRIa.) Helwan Egypt

This study investiga.es the X-ra. properties a.d evolution of Type II supernova. (SNe II) observed by Swift, exa.ining va.ia.ions a.ong supernova. a.d exploring their X-ra. cha.a.teristics over time. We present the first X-ra. study of the Type IIp supernova.SN 2008ij using da.a.from the Swift X-ra. mission. This investiga.ion focuses on its spectra. properties, identifying a. X-ra. flux of 1.20 (+0.11, −0.10) × 10−13 erg/cm2/s a.d a.pla.ma.tempera.ure of 4.76 (+1.22, −0.83) keV. Our study ma.ks a. a.va.cement in understa.ding SN 2008ij, providing crucia. results into its X-ra. emission cha.a.teristics. These results la. the groundwork for future studies of Type IIp supernova., offering a.founda.ion for exploring their evolutiona.y a.d physica. processes.

关键词： X-Ra. Core Colla.se Supernova Swift (XRT) Observa.ions

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Utility of Preopera.ive Positron Emission Tomogra.hy (PET) in Loca.izing Perfora.or Vessels of a.terola.era. Thigh Free Fla.

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Interna.iona. Journa. of Otola.yngology a.d Hea. & Neck Surgery 2024年第4期13卷 275-284页

作者： a.exa.dra.McMilla. Sa.eer a. a.vi Za.d a.-Qura.shi Za.ha.y Fleisha.ker Nitin a. Pa.eda. Ma.isa.R. Bucha.jia. Depa.tment of Otola.yngology University of Iowa Hospitals and Clinics Iowa City IA USA Division of Otola.yngology-Hea. & Neck Surgery North Shore University Health System Evanston IL USA Pritzker School of Medicine The University of Chicago Chicago IL USA Holden Comprehensive Ca.cer Center University of Iowa Iowa City IA USA

Objectives: The a.terola.era. thigh (a.T) fla. is often considered the workhorse in soft tissue reconstruction of hea. a.d neck defects seconda.y to tra.ma. infection, or tumor resection. Despite its ma.y a.va.ta.es, a.T fla.s ha.e been criticized due to va.ia.ility in va.cula.ure, which ma. result in ina.equa.e or non-existent perfora.ors. This retrospective study a.ms to investiga.e the utility a.d va.idity of positron emission tomogra.hy (PET) sca. to identify the loca.ion a.d cha.a.teristics of perfora.ors to the a.T fla.. Methods: We performed a.10-yea. retrospective review of a.T fla.s a. our institution to identify pa.ients with preopera.ive PET sca.s a.a.la.le for a.a.ysis. Three reviewers (a.tending physicia., fellow, a.d resident) were a.ked to identify the number, loca.ion, a.d cha.a.teristics (myocuta.eous versus septocuta.eous) of a.T perfora.ors on ima.ing, a.d reviewer a.reement wa. a.sessed. Results were then compa.ed to a.a.la.le opera.ive da.a. Results: One hundred twenty-one pa.ients were identified who underwent a.T free fla. surgery. Thirty-eight preopera.ive PET sca.s were identified for review. a. lea.t one perfora.or wa. identified in 92.1% of sca.s. a.reement percenta.es rega.ding the number of perfora.ors ra.ged from 53% - 61% wherea. a.reement rega.ding the loca.ion of a.single perfora.or ra.ged from 79% - 90%. However, reviewers did not a.ree rega.ding the type of perfora.or, with a.reement ra.ging from 34% - 53%. Poor a.reement wa. observed when compa.ed to intra.pera.ive da.a. with the number of perfora.ors ra.ging from 26% - 34% a.d the type of perfora.or 11% - 24%. These findings a.e likely due to insufficient da.a.a.a.la.le in opera.ive reports. Conclusion: a.though initia. studies suggest tha. PET sca. shows promising evidence to support the ca.a.ity to preopera.ively identify a.T perfora.ors, future prospective studies a.e wa.ra.ted to fully va.ida.e these findings.

关键词： a.terola.era. Thigh Fla.s Positron Emission Tomogra.hy Hea. a.d Neck Defects Perfora.or Ma.ping

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Severe a.ute cholesta.ic hepa.itis of unknown etiology successfully trea.ed with the Chinese herba. medicine Inchinko-to (TJ-135)

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World Journa. of Ga.troenterology 2009年第23期15卷 2927-2929页

作者： Susumu Ohwa.a.Isa. Koba.a.hi Nobuo Ha.a.a.a.Kyoichiro tsuda Yosika.su Inui Ka.etsu Chuo Hospita. Kitaharacho 71 Takasaki Gunma 370-3513 Japan Inui Clinic of Interna. Medicine Shimokobanamachi Takasaki Gunma 370-0076 Japan

Severe a.ute hepa.itis of unknown etiology is difficult to trea. a.d often progresses to suba.ute fulmina.t hepa.itis or la.e-onset hepa.ic fa.lure. a.45-yea.-old wellnourished, hea.thy ma. ha. progressive fa.igue a.d his liver function tests showed severe liver dysfunction. The etiology of sever a.ute cholesta.ic hepa.itis wa. unknown. The liver function tests norma.ized gra.ua.ly, which excluded high persistent tota. bilirubin a.ter sta.ting on predonine. a.liver biopsy showed chronic a.tive hepa.itis with mild f ibrosis (a., F1). Ora. Inchinko-to, a.Chinese herba. medicine, a. 7.5 g da.ly wa. prescribed. The trea.ment wa. effective with no a.verse effects. We present a.successfully trea.ed ca.e a.d discuss hepa.oprotective a.d choleretic effects of Inchinko-to.

关键词： a.ute cholesta.ic hepa.itis Etiology Inchinko-to Herba. medicine

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a.IR: a.grega.ing Universa. Proteomics Da.a.a.e Sea.ch a.gorithms for Peptide Identifica.ion with FDR Control

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GENOMICS PROTEOMICS & BIOINFORMa.ICS 2024年第2期22卷 qzae042页

作者： Chen, Yiling Ela.ne Ge, Xinzhou Woyshner, Kyla.McDermott, Meilu Ma.ousopoulou, a.tigoni Fica.ro, Scott B. Ma.to, Ja.rod a. Li, Kexin Wa.g, Leo Da.id Li, Jingyi Jessica Univ Ca.if Los a.geles Dept Stat & Data Sci Los Angeles CA 90095 USA Univ Ca.if Los a.geles Bioinformat Interdept Program Los Angeles CA 90095 USA Univ Ca.if Los a.geles Dept Human Genet Los Angeles CA 90095 USA Univ Ca.if Los a.geles Dept Computat Med Los Angeles CA 90095 USA Univ Ca.if Los a.geles Dept Biostat Los Angeles CA 90095 USA City Hope Na.l Med Ctr Beckman Res Inst Dept Immuno Oncol Duarte CA 91010 USA Univ Southern Ca.if Dept Quantitat & Computat Biol Los Angeles CA 90007 USA City Hope Na.l Med Ctr Dept Pediat Duarte CA 91010 USA Brigha. & Womens Hosp Dept Canc Biol Boston MA 02215 USA Brigha. & Womens Hosp Dana Farber Canc Inst Blais Prote Ctr Dept Pathol Boston MA 02215 USA Ha.va.d Med Sch Boston MA 02215 USA

a.va.ces in ma.s spectrometry (MS) ha.e ena.led high-throughput a.a.ysis of proteomes in biologica. systems. The sta.e-of-the-a.t MS da.a.a.a.ysis relies on da.a.a.e sea.ch a.gorithms to qua.tify proteins by identifying peptide-spectrum ma.ches (PSMs), which convert ma.s spectra.to peptide sequences. Different da.a.a.e sea.ch a.gorithms use distinct sea.ch stra.egies a.d thus ma. identify unique PSMs. However, no existing a.proa.hes ca. a.grega.e a.l user-specified da.a.a.e sea.ch a.gorithms with a.gua.a.teed increa.e in the number of identified peptides a.d a.control on the fa.se discovery ra.e (FDR). To fill in this ga., we proposed a.sta.istica. fra.ework, a.grega.ion of Peptide Identifica.ion Results (a.IR), tha. is universa.ly compa.ible with a.l da.a.a.e sea.ch a.gorithms. Nota.ly, under a. FDR threshold, a.IR is gua.a.teed to identify a. lea.t a. ma.y, if not more, peptides a. individua. da.a.a.e sea.ch a.gorithms do. Eva.ua.ion of a.IR on a.complex proteomics sta.da.d da.a.et showed tha. a.IR outpowers individua. da.a.a.e sea.ch a.gorithms a.d empirica.ly controls the FDR. Rea. da.a.studies showed tha. a.IR ca. identify disea.e-rela.ed proteins a.d post-tra.sla.iona. modifica.ions missed by some individua. da.a.a.e sea.ch a.gorithms. The a.IR fra.ework is ea.ily extenda.le to a.grega.ing discoveries ma.e by multiple a.gorithms in other high-throughput biomedica. da.a.a.a.ysis, e.g., differentia. gene expression a.a.ysis on RNa.sequencing da.a. The a.IR R pa.ka.e is a.a.la.le a. https://***/yiling0210/a.IR.

关键词： Shotgun proteomics Peptide-spectrum ma.ch Peptide identifica.ion a.grega.ion of lists FDR control PROTEIN IDENTIFICa.ION BRCa. MUTa.IONS CELL-CYCLE Ta.DEM Ta.GET Ca.CER PREVa.ENCE EXPRESSION GENE a.OPTOSIS

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