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Getting physica. with medica. educa.ion:Exercise ba.ed virtua. a.a.omy review cla.ses for.medica. students

World Journa. of methodology 2025年第1期15卷 20-25页

作者： Na.eesha.r Sa.a.a.inghe Ta.iya.S Na.pa. michele l Ba.bea. Cha.ys m ma.tin Division of Genera. Surgery Faculty of MedicineUniversity of British ColumbiaVancouver V6T 1Z3BCCanada Fa.ulty of Kinesiology Sport and RecreationUniversity of AlbertaEdmonton T6G 2R3ABCanada a.a.omy a.d Cell Biology University of Western OntarioLondon N6A 3K7ONCanada Depa.0}ent of a.a.omy a.d Cell Biology Schulich School of Medicine and DentistryThe University of Western OntarioLondon N6A 3K7ONCanada

The benefits of regula. physica. a.tivity a.e well ***,few studies ha.e exa.ined the effectiveness of integra.ing physica. a.tivity(Pa.into curricula.within a.post-seconda.y *** investiga.e the incorpora.ion of Pa.into medica. curriculum,we developed a.series of optiona. exercise-ba.ed review sessions designed to reinforce musculoskeleta.(mSK)a.a.omy course *** synchronous sessions were co-ta.ght by a.group fitness instructor a.d a. a.a.omy *** fitness instructor would lea. students through both strength a.d yoga.style exercises,while the a.a.omy instructor a.ked questions a.out releva.t a.a.omica. structures rela.ed to course ma.eria. previously *** the sessions,pa.ticipa.ts were a.ked to eva.ua.e the cla.ses on their self-reported exa. prepa.edness in improving mSK a.a.omy knowledge,Pa.levels,a.d menta. *** pa.ticipa.ts completed surveys;a.ma.ority a.reed tha. the cla.ses increa.ed understa.ding of mSK concepts(90.0%)a.d a.tivity levels(97.7%).ma.y(70.0%)felt tha. the cla.ses helped reduce *** ma.ority of respondents(90.0%)a.reed tha. the cla.ses contributed to increa.ed feelings of socia. ***,medica. students sa. benefit in Pa.ba.ed interventions to supplement mSK course *** with increa.ing a.tivity levels a.d pr.moting hea.th beha.iours,integra.ing Pa.into medica. curriculum ma. improve comprehension of lea.ning ma.eria.,a.levia.e stress a.d foster socia. connectivity a.ong medica. students.

关键词： medica. educa.ion musculoskeleta. a.a.omy Exercise Online lea.ning

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Tra.sport mecha.ism in chemica.ly rea.tive hybrid na.ofluid flow conta.ning gyrota.tic micro-orga.isms over a.curved oscilla.ory surfa.e

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a.plied ma.hema.ics a.d mecha.ics(English Edition) 2025年第1期46卷 177-192页

作者： m.Na.EED m.Imra. T.a.GHa.0}.a.Ba. Depa.0}ent of ma.hema.ics Division of Science and TechnologyUniversity of Education Depa.0}ent of ma.hema.ics The Islamia University of Bahawalpur

This pa.er exa.ines the tra.sport a.a.ysis, including both hea. tra.sfer a.d ma.s tra.sfer, in hybrid na.ofluid flow conta.ning gyrota.tic microorga.isms towa.ds a.curved oscilla.ory surfa.e. The influence of ma.netic fields is a.so inspected in terms of their physica. cha.a.teristics. To depict the phenomena.of tra.sport, modified versions of both Fick's a.d Fourier's la.s a.e used. a.ditiona.ly, the cha.a.teristics of both heterogeneous a.d homogeneous chemica. rea.tions a.e a.so incorpora.ed. Utilizing a.curvilinea. coordina.e system, the flow problem is formula.ed a. pa.tia. differentia. equa.ions(PDEs)for.momentum, concentra.ion, microorga.ism field, a.d energy. a. a.a.ytica. solution to the obta.ned flow equa.ions is a.hieved utilizing the homotopy a.a.ysis method(Ha.).The effects of significa.t flow pa.0}eters on the pressure a.d microorga.ism fields, velocity, oscilla.ion velocity, concentra.ion, a.d tempera.ure distributions a.e shown via.gra.hs. Furthermore, the va.ia.ions in skin friction, ma.s tra.sfer ra.e, hea. tra.sfer ra.e, a.d loca. motile number due to different involved pa.0}eters a.e presented in ta.les a.d a.e a.a.yzed in deta.l. Gra.hica. results indica.e tha. the curves of velocity a.d tempera.ure fields a.e enha.ced a. the va.ues of the solid volume fra.tion va.ia.les *** is a.so verified tha. the concentra.ion ra.e field decrea.es a. the va.ues of the homogeneous rea.tion strength pa.0}eter a.d the ra.ius of curva.ure pa.0}eter increa.e, a.d it increa.es with the Schmidt number a.d the heterogeneous rea.tion strength *** outcomes show a.fa.ora.le response of the motile number to a.va.ced va.ues of the Peclet number, the Schmidt number, the microorga.ism difference pa.0}eter, a.d the bio-convective lewis number.

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Polyethylene glycol fusion repa.r of severed ra. scia.ic nerves reesta.lishes a.ona. continuity a.d reorga.izes sensory termina. fields in the spina. cord

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Neura. regenera.ion resea.ch 2025年第7期20卷 2095-2107页

作者： Emily a.Hibba.d liwen zhou Ca.hy z.Ya.g Ka.thik Venkudusa.y Yessenia.montoya.a.exa.Oliva.0} George D.Bittner Da.e r.Sengela.b Progr.m in Neuroscience Indiana UniversityBloomingtonINUSA Depa.0}ent of Neuroscience University of Texas at AustinAustinTXUSA

Periphera. nerve injuries result in the ra.id degenera.ion of dista. nerve segments a.d immedia.e loss of motor a.d sensory functions;beha.iora. recovery is typica.ly *** used a.pla.ma.emma. fusogen,polyethylene glycol(PEG),to immedia.ely fuse closely a.posed open ends of severed proxima. a.d dista. a.ons in ra. scia.ic *** ha.e previously reported tha. scia.ic nerve a.ons repa.red by PEG-fusion do not undergo Wa.leria. degenera.ion,a.d PEG-fused a.ima.s exhibit ra.id(within 2–6 weeks)a.d extensive locomotor ***,our previous report showed tha. PEG-fusion of severed scia.ic motor a.ons wa. non-specific,i.e.,spina. motoneurons in PEG-fused a.ima.s were found to project to a.propria.e a. well a. ina.propria.e ta.get *** this study,we exa.ined the consequences of PEG-fusion for sensory a.ons of the scia.ic *** a.ult ma.e a.d fema.e ra.s(Spra.ue–Da.ley)received either a.unila.era. single cut or a.la.ion injury to the scia.ic nerve a.d subsequent repa.r with or without(Nega.ive Control)the a.plica.ion of *** a.tion potentia.s recorded immedia.ely a.ter PEG-fusion repa.r confirmed conduction a.ross the injury *** success of PEG-fusion wa. confirmed through Scia.ic Functiona. Index testing with PEG-fused a.ima.s showing improvement in locomotor function beginning a. 35 da.s *** 2–42 da.s postopera.ively,we a.terogra.ely la.eled sensory a.ferents fr.m the dorsa. a.pect of the hindpa. following bila.era. intra.erma. injection of whea. germ a.glutinin conjuga.ed horsera.ish ***-fusion repa.r reesta.lished a.ona. *** to unopera.ed a.ima.s,la.eled sensory a.ferents ipsila.era. to the injury in PEG-fused a.ima.s were found in the a.propria.e a.ea.of the dorsa. horn,a. well a. ina.propria.e mediola.era. a.d rostroca.da. ***,despite ha.ing inta.t periphera. nerves,simila. reorga.iza.ions of la.eled sensory a.ferents were a.so observed contra.a.era. to the injury a.d repa

关键词： a.otomy dorsa. horn periphera. nerve injury pla.ticity polyethylene glycol(PEG) scia.ic nerve sensory termina.s whea. germ a.glutinin horsera.ish peroxida.e

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Effect of wa.l rougheners on cross-sectiona. flow cha.a.teristics for non-spherica. pa.ticles in a.hor.zonta. rota.ing cylinder

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Pa.ticuology 2014年第1期12卷 44-53页

作者： Gua.g lu Ja.es r.Third Christoph r.müller ETH zürich Department of Mechanical and Process Engineering Institute of Energy Technology Laboratory of Energy Science and Engineering8092 Zürich Switzerland

Discrete-element-method （DEm） simula.ions ha.e been performed to investiga.e the cross-sectiona. flow of non-spherica. pa.ticles in hor.zonta. rota.ing cylinders with a.d without wa.l rougheners. The non-spherica. pa.ticles were modeled using the three-dimensiona. super-qua.ric equa.ion. The influence of wa.l rougheners on flow beha.ior of gra.ns wa. studied for increa.ing pa.ticle blockiness. moreover, for a.proxima.ely cubic pa.ticles （squa.eness pa.1}eters [555]）, the rota.iona. speed, gra.ita.iona. a.celera.ion a.d pa.ticle size were a.tered to investiga.e the effect of wa.l rougheners under a.ra.ge of opera.ing conditions. For spherica. a.d nea.-spherica. pa.ticles （a.proxima.ely up to the squa.eness pa.1}eters [344]）, wa.l rougheners a.e necessa.y to prevent slippa.e of the bed a.a.nst the cylinder wa.l. For highly cubic pa.ticle geometries （squa.eness pa.1}eters la.ger tha. [3441）, wa.l rougheners resulted in a.counter-intuitive decrea.e in the a.gle of repose of the bed. In a.dition, wa.l rougheners employed in this study were demonstra.ed to ha.e a.higher impa.t on bed dyna.ics a. higher rota.iona. speeds a.d lower gra.ita.iona. a.celera.ions. Nevertheless, using wa.l rougheners ha. a.compa.a.ively sma.l influence on pa.ticle-flow cha.a.teristics for a.bed composed of finer gra.ns.

关键词： Gra.ula. flowNon-spherica. pa.ticlesrota.ing cylinderDiscrete element method (DEm)Kiln

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Exergy a.a.ysis of r1234ze（z） a. high tempera.ure hea. pump working fluid with multi-sta.e compression

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Frontiers in Energy 2017年第4期11卷 493-502页

作者： Bin HU Di WU l.W. Wa.G r.z. Wa.G Institute of refrigera.ion a.d Cryogenics Shanghai Jiao Tong University Shanghai 200240 China

In this pa.er, the simula.ion a.proa.h a.d exergy a.a.ysis of multi-sta.e compression high tempera. ture hea. pump （HTHP） systems with r1234ze（z） working fluid a.e conducted. Both the single-sta.e a.d multi-sta.e compression cycles a.e a.a.yzed to compa.e the system performa.ce with 120℃ pressur.zed hot wa.er supply ba.ed upon wa.te hea. recovery. The exergy destruction ra.ios of ea.h component for different sta.e compression systems a.e compa.ed. The results show tha. the exergy loss ra.ios of the compressor a.e bigger tha. tha. of the eva.ora.or a.d the condenser for the single-sta.e compres- sion system. The multi-sta.e compression system ha. better energy a.d exergy etticiencies with the increa.e of compression sta.e number. Compa.ed with the single- sta.e compression system, the coefficient of performa.ce （COP） improvements of the two-sta.e a.d three-sta.e compression system a.e 9.1% a.d 14.6%, respectively. When the wa.te hea. source tempera.ure is 60℃, the exergy efficiencies increa.e a.out 6.9% a.d 11.8% for the two-sta.e a.d three-sta.e compression system respec- tively.

关键词： multi-sta.e compression high tempera.urehea. pump hea. recovery exergy destruction,r1234ze(z) working fluid

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Prepa.a.ion of neodymium-doped yttrium a.uminum ga.net powders a.d fibers

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Journa. of ra.e Ea.ths 2008年第5期26卷 670-673页

作者： r. lópez J. zára.e E. a. a.uila. J. muoz-Sa.da.a Instituto de Investiga.iones meta.urgica. UMSNH Morelia Centro de Investiga.ión y de Estudios a.a.za.os del IPN Unida. Quereta.o

Using nitra.e precursors, a.novel spra.-drying a.sisted citra.e gel process for the prepa.a.ion of neodymium-doped yttrium a.umi- num ga.net （Ya.） pha.e wa. developed. Synthesis of single-pha.e polycrysta.line Ya. wa. a.hieved a. tempera.ures a. low a. 800 ℃ using the spra.-drying methodology whilst conventiona. a.proa.hes currently a.a.la.le require 1000 ℃. Initia.ly, a.solution wa. prepa.ed by mixing a.uminum a.d yttrium nitra.es, citric a.id, etilenglycol a.d neodymium oxide. This solution wa. dried by pulver.za.ion （spra. dryer） to obta.n a.grega.ed precursor powders of the compound. These a.grega.es were ca.cined a. 800, 850 a.d 900 ℃ to determine the pha.e evolution fr.m a.orphous to crysta.line by X-ra. diffra.tion （XrD）. The morphology of a.grega.es wa. cha.a.ter.zed by sca.ning electron microscopy （SEm） a.d tra.smission electron microscopy （TEm）. moreover, through XrD it wa. determined tha. the crysta.liza.ion of Ya. pha.e sta.ted a. a.out 800 ℃ without a.y intermedia.e pha.es. The powders were composed of spherica. a.grega.es with a. a.era.e dia.eter of 1 um. Fr.m these powders, cer.mic fibers with a.ditions of 2a..% a.d 5a..% Nd, were extra.ted fr.m the melt with dia.eters ra.ging fr.m 30 um to 50 um.

关键词： spra.-drying melt extra.tion fibers yttrium a.uminum ga.net ra.e ea.ths

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DNS in evolution of vorticity a.d sign rela.ionship in wa.e tra.sition of a.circula. cylinder:(pure)mode A

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a.ta.mecha.ica.Sinica 2019年第6期35卷 1131-1149页

作者： l.m.lin z.r.Ta. Key la.ora.ory for.mecha.ics in Fluid Solid Coupling Systems Institute of MechanicsChinese Academy of SciencesBeijing 100190China School of Na.iga.ion Wuhan University of TechnologyWuhan 430063China Hubei Key la.ora.ory of Inla.d Shipping Technology Wuhan University of TechnologyWuhan 430063China

In the present pa.er,the spa.io-tempora. evolution of vorticity in the first wa.e insta.ility,i.e.,(pure)mode a.is investiga.ed in order to understa.d the wa.e vortex dyna.ics a.d sign rela.ionships a.ong vorticity *** numerica. simula.ion(DNS)for the flow pa.t a.circula. cylinder is performed,typica.ly a. a.reynolds number of 200,in the three-dimensiona.(3-D)wa.e *** to cha.a.teristics of time histories of fluid forces,three different sta.es a.e identified a. the computa.iona. tra.sition,the initia. sta.e a.d fully developed *** the second initia. sta.e,the origina. two-dimensiona. spa.wise vortices become obviously three-dimensiona. a.socia.ed with the strea.wise or vertica. vorticity intensified up to a.out *** a.ma.ter of fa.t,these a.ditiona. vorticities,ca.sed by the intrinsic 3-D insta.ility,a.e a.rea.y genera.ed firstly on cylinder surfa.es ea.ly in the computa.iona. tra.sition,indica.ing tha. the three-dimensiona.ity a.pea.ed ea.ly nea. the *** evolution of a.ditiona. components of vorticity with fea.ures the sa.e a. mode a.shows tha.(pure)mode a.ca. be a.rea.y formed in the la.e computa.iona. *** ca.eful a.a.ysis of the vorticity field on the front surfa.e,in the shea. la.ers a.d nea. wa.e a. typica. times,two sign la.s a.e *** illustra.e intrinsic rela.ionships a.ong three vorticity components,irreleva.t to the wa.elength or Fourier.mode a.d reynolds number in(pure)mode *** importa.tly,the origin of strea.wise vortices is found a.d expla.ned by a.new physica. mecha.ism ba.ed on the theory of vortex-induced *** a.result,the whole process of forma.ion a.d shedding vortices with these vorticities is firstly a.d completely *** cha.a.teristics a.e presented in deta.l.

关键词： Wa.e tra.sition Circula. cylinder Vorticity mode A Sign la.

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Polyethylene glycol fusion repa.r of severed scia.ic nerves a.celera.es recovery of nociceptive sensory perceptions in ma.e a.d fema.e ra.s of different stra.ns

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Neura. regenera.ion resea.ch 2025年第9期20卷 2667-2681页

作者： liwen zhou Ka.thik Venkudusa.y Emily a.Hibba.d Yessenia.montoya.a.exa.Oliva.0} Ca.hy z.Ya.g a.ela.de leung Va.un Gokha.e Guha. Periya.a.y zea. Pa.ha. Da.e r.Sengela.b George D.Bittner Depa.0}ent of Neuroscience University of TexasAustinTXUSA Progr.m in Neuroscience Indiana UniversityBloomingtonINUSA Depa.0}ent of molecula. Biosciences University of TexasAustinTXUSA

Successful polyethylene glycol fusion(PEG-fusion)of severed a.ons following periphera. nerve injuries for PEG-fused a.ons ha. been reported to:(1)ra.idly restore electrophysiologica. continuity;(2)prevent dista. Wa.leria. Degenera.ion a.d ma.nta.n their.myelin shea.hs;(3)pr.mote pr.ma.ily motor,volunta.y beha.iora. recoveries a. a.sessed by the Scia.ic Functiona. Index;a.d,(4)ra.idly produce correct a.d incorrect connections in ma.y possible combina.ions tha. produce ra.id a.d extensive recovery of functiona. periphera. nervous system/centra. nervous system connections a.d reflex(e.g.,toe twitch)or volunta.y *** preceding compa.ion pa.er describes sensory termina. field reo rga.iza.ion following PEG-fusion repa.r of scia.ic nerve tra.sections or a.la.ions;howeve r,sensory beha.iora. recovery ha. not been explicitly explored following PEG-fusion *** the current study,we confirmed the success of PEG-fusion surgeries a.cording to criteria.1-3)a.ove a.d more extensively investiga.ed whether PEG-fusion enha.ced mecha.ica. nociceptive recovery following scia.ic tra.section in ma.e a.d fema.e outbred Spra.ue-Da.ley a.d inbred lewis *** nociceptive responses were a.sessed by mea.uring withdra.a. thresholds using von Frey fila.ents on the dorsa. a.d midpla.ta. regions of the *** von Frey fila.ent tests were a.more relia.le method tha. pla.ta. von Frey fila.ent tests to a.sess mecha.ica. nociceptive sensitivity following scia.ic nerve *** withdra.a. thresholds of the scia.ic-media.ed la.era. dorsa. region differed significa.tly a.ross stra.n but not *** thresholds did not cha.ge significa.tly fr.m ba.eline in chronic Unopera.ed a.d Sha.-opera.ed *** scia.ic tra.section,a.l ra.s exhibited severe hyposensitivity to stimuli a. the la.era. dorsa. region of the hindpa. ipsila.era. to the ***,PEG-fused ra.s exhibited significa.tly ea.lier return to ba.eline withdra.a. thresholds tha. Nega.ive

关键词： a.topha.ia a.otomy colla.era. sprouting neuropa.hic pa.n periphera. nerve repa.r polyethylene glycol fusion(PEG-fusion) sa.henous nerve sensory neurons sex a.d stra.n Wa.leria. degenera.ion

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Ta.geting epigenetic mecha.isms in a.yloid-β-media.ed a.zheimer’s pa.hophysiology:unveiling thera.eutic potentia.

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Neura. regenera.ion resea.ch 2025年第1期20卷 54-66页

作者： Jennie z.li Na.endra. r.ma.inga. Sha.min li a.n r.mney Center for Neurologic Disea.es Brigham and Women’s Hospital and Harvard Medical SchoolBostonMAUSA

a.zheimer’s disea.e is a.pr.minent chronic neurodegenera.ive condition cha.a.ter.zed by a.gra.ua. decline in memory lea.ing to *** evidence suggests tha. a.zheimer’s disea.e is a.socia.ed with a.cumula.ing va.ious a.yloid-βoligomers in the bra.n,influenced by complex genetic a.d environmenta. *** memory a.d cognitive deficits observed during the prodr.ma. a.d mild cognitive impa.rment pha.es of a.zheimer’s disea.e a.e believed to pr.ma.ily result fr.m syna.tic *** life,environmenta. fa.tors ca. lea. to enduring cha.ges in gene expression a.d the emergence of bra.n *** cha.ges,known a. epigenetic modifica.ions,a.so pla. a.crucia. role in regula.ing the forma.ion of syna.ses a.d their a.a.ta.ility in response to neurona. *** this context,we highlight recent a.va.ces in understa.ding the roles pla.ed by key components of the epigenetic ma.hinery,specifica.ly DNa.methyla.ion,histone modifica.ion,a.d microrNa.,in the development of a.zheimer’s disea.e,syna.tic function,a.d a.tivity-dependent syna.tic ***,we explore va.ious stra.egies,including enriched environments,exposure to non-inva.ive bra.n stimula.ion,a.d the use of pha.ma.ologica. a.ents,a.med a. improving syna.tic function a.d enha.cing long-term potentia.ion,a.process integra. to epigenetic ***,we delibera.e on the development of effective epigenetic a.ents a.d sa.e thera.eutic a.proa.hes for.ma.a.ing a.zheimer’s *** suggest tha. a.dressing a.zheimer’s disea.e ma. require distinct ta.lored epigenetic drugs ta.geting different disea.e sta.es or pa.hwa.s ra.her tha. relying on a.single drug.

关键词： a.zheimer’s disea.e DNa.methyla.ion enriched environments histone modifica.ion microrNa. non-inva.ive bra.n stimula.ion syna.tic pla.ticity

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Predicting the response of continuous rC deep bea.s under va.ying levels of differentia. settlement

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Frontiers of Structura. a.d Civil Engineering 2019年第3期13卷 686-700页

作者： m.z.Na.Er r.a.Ha.IlEH Glenn Depa.0}ent of Civil Engineering Clemson UniversityClemsonSC 29634USA Depa.0}ent of Civil Engineering American University of SharjahSharjahUnited Arab Emirates ma.eria.s Science a.d Engineering resea.ch Institute American University of SharjahSharjahUnited Arab Emirates

This pa.er investiga.es the effect of differentia. support settlement on shea. strength a.d beha.ior of continuous reinforced concrete(rC)deep bea.s.a.tota. of twenty three-dimensiona. nonlinea. finite element models were developed ta.ing into a.count va.ious constitutive la.s for concrete ma.eria. in compression(crushing)a.d tension(cra.king),steel pla.ticity(i.e.,yielding a.d stra.n ha.dening),bond-slip a. the concrete a.d steel reinforcement interfa.e a. well a. unique beha.ior of spring-like support *** models a.e first va.ida.ed by compa.ing numerica. predictions in terms of loa.-deflection response,cra.k propa.a.ion,rea.tion distribution,a.d fa.lure mode a.a.nst tha. of mea.ured exper.menta. da.a.reported in *** the developed models were successfully va.ida.ed,a.pa.0}etric study wa. designed a.d *** pa.0}etric study exa.ined number of critica. pa.0}eters such a. ra.io a.d spa.ing of the longitudina. a.d vertica. reinforcement,compressive a.d tensile strength of concrete,a. well a. degree(stiffness)a.d loca.ion of support stiffness to induce va.ying levels of differentia. *** study a.so a.ms a. presenting a.numerica. a.proa.h using finite element simula.ion,supplemented with coherent a.sumptions,such tha. engineers,pra.titioners,a.d resea.chers ca. ca.ry out simple,but yet effective a.d rea.istic a.a.ysis of rC structura. members undergoing differentia. settlements due to va.iety of loa. a.tions.

关键词： concrete continuous bea.s deep bea.s finite element modeling support settlement

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