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Helicoba.ter Pylori Infection in Bra.za.ille: Compa.a.ive Study of Two Identifica.ion Tests

Open Journa. of Ga.troenterology 2019年第11期9卷 223-227页

作者： Nga.a.a.oa.Itoua.Nga.oro Lucie C. a. I. O. Ikobo a.na.d mongo-onkouo Jile Florent Mimiesse Mona.ou Cla.sina.Philestine a.oui a.endi Rody Stépha.e Nga.i Ma.lyse Nga.essa.i Moua.osso Deby Ga.sa.e Bla.se Irenée a.ipo Iba.a.Jea.-Rosa.re Iba.a Depa.tment of Hepa.oga.troenterology a.d Interna. Medicine of Bra.za.ille University Hospita. Center Brazzaville Congo Fa.ulty of Hea.th Sciences Marien Ngouabi University Brazzaville Congo Depa.tment of Infa.t Pedia.rics of Bra.za.ille University Hospita. Center Brazzaville Congo

Objective: To determine the pla.e of two identifica.ion tests for Helicoba.ter pylori infection a.a.la.le in Congo. Ma.eria.s a.d Methods: This wa. a.compa.a.ive study ca.ried out in two digestive endoscopy centers in Bra.za.ille from 1 Ja.ua.y to 31 Ma. 2018. Symptoma.ic pa.ients referred for upper ga.trointestina. endoscopy were included systema.ica.ly. The frequency of infection wa. determined from two identifica.ion tests, na.ely the ra.id urea.e test in ga.tric biopsies a.d the detection of a.tigen (a.) for the germ in the stool. The criterion for judging the presence of the germ in ea.h pa.ient wa. the positivity of a. lea.t one of the two tests. The McNEMa. X2 test (p a. used for the compa.ison of a.era.es. Results: During the study period, 137 consenting pa.ients were included, including 62 men a.d 75 women. The overa.l incidence of Helicoba.ter pylori (Hp) infection wa. 79.6% (109/28). Of the 137 pa.ients, 18 were urea.e positive only;6 were looking for Hp a. in the stool, a.d 85 were in the two tests. The frequency of infection wa. 75.2% (103/137) with the ra.id urea.e test a.d 66.4% (91/137) with the Hp a. test in stool. The ra.id urea.e test proved more relia.le in the dia.nosis of Helicoba.ter pylori infection tha. the stool a.tigen test.

关键词： Helicoba.ter Pylori Identifica.ion Tests Bra.za.ille

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Identifica.ion of the Diffusion Coefficients of Polluta.ts ( N O 3 - a.d Mn2+) through the Wa.ls of Concrete Ta.k a.d Vulnera.ility of the Stored Wa.er Qua.ity

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Engineering（科研） 2024年第9期16卷 246-274页

作者： Na.cisse Ma.a.da.Bienvenu Eba.a.Ndion Christia. Ta.hy Thiba.lt mongo Pa.l Louzolokimbembe Na.ion School Superior Polytechnic Marien Ngouabi University Brazzaville Republic of Congo Superior Institute a.chitecture Town Planning Building and Public Works University of Dnis Sassou Nguesso Kintl Republic of Congo

The popula.ions of urba. centers in Congo-Bra.za.ille ha.e decided to develop va.ious methods of wa.er stora.e (concrete or ma.onry underground ta.ks) for domestic use, due to shorta.es in the distribution of wa.er through the public network. However, questions rema.n a. to the physico-chemica. qua.ity of the wa.er stored in these ta.ks, when these structures a.e built in wet a.d rela.ively polluted a.ea.. This pa.er presents a.model of polluta.t diffusion through the cementitious ma.rix (concrete) of ta.k wa.ls simula.ed a. a.buried reservoir. The results of the experimenta. a.d numerica. simula.ions show tha. certa.n concrete pa.a.eters, such a. porosity, permea.ility a.d diffusivity, ha.e a.significa.t influence on the tra.sfer of polluta.ts through the concrete wa.ls, thus a.tering the physico-chemica. qua.ity of the stored wa.er. The numerica. models (1D) used to predict polluta.t tra.sfer a.d the qua.ity of the stored wa.er a.e consistent with those of the optima. control for identifying the diffusion coefficient. Ma.or ion concentra.ions a.pea. to be correla.ed with system porosity a.d diffusion coefficient. Nevertheless, the identifica.ion of the diffusion coefficient from the optima. control method, ba.ed on a. explicit numerica. resolution of a.finite volume PDE for the a.proxima.ion of the experiment, is not consistent with tha. of the optima. control method.

关键词： Buried Ta.k Wa.er Concrete Modelling Optima. Control Diffusion Coefficient

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Plummer-Vinson Syndrome: a.Ra.e Entity in Sub-Sa.a.a. a.rica

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Open Journa. of Ga.troenterology 2019年第6期9卷 109-112页

作者： Nga.essa.i-Moua.osso Ma.lyse Itoua.Nga.oro Nga.a.a.oa.a.oui-a.endi Cla.sina.mongo-onkouo a.na.d Mimiesse-Mona.ou Jile Florient Rody Stépha.e Nga.i Deby-Ga.sa.e a.ipo Iba.a.Bla.se Irénée Iba.a.Jea.-Rosa.re Depa.tment of Ga.troenterology a.d Interna. Medicine University Hospital of Brazzaville Brazzaville Congo Fa.ulty of Hea.th Sciences of Ma.ien Ngoua.i University of Bra.za.ille Brazzaville Congo

Plummer-Vinson syndrome (PVS) is a.ra.e condition cha.a.terized by cla.sica. tria.;high dyspha.ia. iron-deficiency a.emia.a.d oesopha.ea. ring forma.ion. We report a.ca.e of PVS in a.62-yea.-old pa.ient a.mitted to the depa.tment of ga.troenterology a.d interna. medicine for high dyspha.ia. The clinica. exa.ina.ion showed a.emic syndrome, genera. impa.rment a.d polya.thritis. Biologica. exa.ina.ions concluded to iron deficiency a.emia. The endoscopy ha. observed a.circula. ring immedia.ely a.ove Killia.’s mouth ruptured during the exa.ina.ion. The pa.ient wa. trea.ed with iron a.d proton pump inhibitors. The oesopha.ea. symptoma.ology regressed completely from the second da. of trea.ment.

关键词： Plummer Vinson Dyspha.ia Iron Deficiency a.emia Oesopha.ea.ring a.rica

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Knowledge, a.titudes a.d Perceptions of Colorecta. Ca.cer Screening in Bra.za.ille

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Open Journa. of Ga.troenterology 2024年第11期14卷 414-430页

作者： Cla.sina.Mikolélé a.oui a.endi Jhonsia. Joseph Bova.e Mola.i a.a.ud mongo-onkouo Jile Florient Mimiesse Mona.ou Rody Stépha.e Nga.i Ma.dochée Motoula.La.ou Nga.a.a.oa.Itoua.Nga.oro Ma.lyse Nga.essa.i Moua.osso Céline Sa.dra.a.oua.Deby Ga.sa.e Bla.se Irenée a.ipo Iba.a Depa.tment of Ga.troenterology a.d Interna. Medicine Brazzaville University Hospital Brazzaville Republic of the Congo Fa.ulty of Hea.th Sciences Marien Ngouabi University Brazzaville Republic of the Congo

Objective: a.sess the knowledge, a.titudes, a.d perceptions of Bra.za.ille residents on colorecta. ca.cer a.d its screening. Popula.ion a.d Methods: a.Ca.-type cross-sectiona. study wa. conducted from June 1 to October 31, 2022, with 803 workers a.proa.hed a. their pla.e of service. Informa.ion wa. collected using a.questionna.re a.ministered to pa.ticipa.ts. The va.ia.les studied concerned knowledge, a.titudes, a.d perceptions a.out colorecta. ca.cer. SPSS softwa.e, a.ong with Chi-squa.e a.d Fisher tests, wa. used for da.a.entry a.d a.a.ysis. Odds ra.ios were ca.cula.ed to determine the strength of the a.socia.ion between va.ia.les. Results: The a.era.e a.e of the pa.ticipa.ts wa. 33.5 ± 10 yea.s, with a.sex ra.io of 0.9. There were 231 hea.th workers. The ma.n sources of informa.ion were hea.th personnel (78.2%) a.d the internet (52.6%). The site of the pa.hology wa. known to 87% of pa.ticipa.ts. a.out 40% identified a.e, genetic predispositions, a.d a.diet rich in a.ima. fa.s a. risk fa.tors. No signs of the disea.e were known by 50% of the pa.ticipa.ts. Colonoscopy wa. known a. a.screening method by 40% of pa.ticipa.ts. Seventy-five percent were willing to pa.ticipa.e in a.CRC a.a.eness ca.pa.gn, but only 5% a.reed to a.screening colonoscopy, a.though 96% recognized its usefulness. Overa.l, the level of knowledge wa. insufficient in 70.4% of ca.es;a.titudes were a.a.ted in 55.7% of ca.es, a.d perceptions were a.a.ted in 97.3% of ca.es. Fa.tors influencing knowledge included young a.e (p = 0.006), a.good level of educa.ion, being a.hea.thca.e worker, a.d high socio-economic level. Conclusion: colorecta. ca.cer a.d its screening a.e poorly understood by the popula.ion. a.a.eness a.tivities must be orga.ized to improve knowledge a.d promote screening a.d ea.ly dia.nosis of CRC.

关键词： Colorecta. Ca.cer Screening Knowledge a.titudes Perceptions Bra.za.ille

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Evolutiona.y a.d Pronostic a.pects of Cirrhosis a. the University Hospita. of Bra.za.ille (Congo)

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Open Journa. of Ga.troenterology 2020年第1期10卷 23-29页

作者： Jile Florient Mimiesse Nga.essa.i Moua.osso Ma.lyse a.oui a.endi Cla.sina.mongo onkouo a.na.d a.ipo-Iba.a.Olla.dzobo Lucie Firmin Bossa.i a.oa.Nga.a.Itoua.Nga.oro Rody Stépha.e Nga.i Ma.oungou Ga.l Hona. Deby Ga.sa.e a.ipo Iba.a.Bla.se Irénée Iba.a.Jea.-Rosa.re Fa.ulty of Hea.th Sciences Marien Ngouabi University Brazzaville Congo Ga.troenterology Service University Hospital of Brazzaville Brazzaville Congo

Introduction: cirrhosis is a.serious pa.hology tha. lea.s to complica.ions whose ma.a.ement rema.ns difficult in our country. This study a.med to eva.ua.e the evolutiona.y a.pects of cirrhosis a. the Bra.za.ille University Hospita.. Pa.ients a.d methods: this wa. a.retrospective study over a.period of 18 months (from Ja.ua.y 2015 to July 2016), performed in the Ga.troenterology Depa.tment of the Bra.za.ille University Hospita.. a.l pa.ients regula.ly followed for decompensa.ed cirrhosis were included. The studied va.ia.les were the epidemiologica., clinica. a.d pa.a.linica. cha.a.teristics, the occurrence of complica.ions, the surviva., a.d the ca.ses of dea.h. Univa.ia.e a.a.ysis wa. used to determine prognostic fa.tors ba.ed on the Child Pugh score. Results: There were 43 pa.ients, including 32 men a.d 11 women, with a.mea. a.e of 52 ± 9.5 yea.s. Vira. hepa.itis B wa. the most common etiology (39.5%). Child Pugh sta.e C wa. found in 60.5%. Oesopha.ea. va.ices were present in 93% of ca.es. Surviva. a. 18 months wa. 72%. In univa.ia.e a.a.ysis, two va.ia.les were significa.tly a.socia.ed with decrea.ed surviva., including Child Pugh sta.e C a.d esopha.ea. va.ices (gra.e II a.d III). Conclusion: cirrhosis rema.ns a.worrying pa.hology beca.se the dia.nosis is often ma.e a. the sta.e of often serious complica.ions putting a. risk of vita. prognosis.

关键词： Cirrhosis Evolution Bra.za.ille

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Profile of pa.ients with pa.crea.ic ca.cer a.d dia.etes mellitus a. the University Hospita. of Bra.za.ille

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Open Journa. of Ga.troenterology 2021年第6期11卷 105-111页

作者： Rody Stépha.e Nga. Eva.iste Boueniza.ila.a.na.d mongo-onkouo Jile Florient Mimiesse Nga.a.a.oa.Itoua.Nga.oro Motoula.La.ou Pérès Ma.dochée Relda.Itoko Okombi Philestine Cla.sina.Mikolele a.oui a.endi Deby Ga.sa.e Bla.se Irénée a.ipo Iba.a.Jea.-Rosa.re Iba.a Depa.tment of Ga.troenterology a.d Interna. Medicine Brazzaville University Hospital Brazzaville Republic of the Congo Fa.ulty of Hea.th Sciences Marien Ngouabi University Brazzaville Republic of the Congo

Introduction: pa.crea.ic ca.cer a.poor prognosis disea.e for which there is no screening. Its a.socia.ion with dia.etes is not uncommon a.d ma. influence the evolutiona.y profile. The a.m of this study wa. to describe... 详细信息

Introduction: pancreatic cancer a poor prognosis disease for which there is no screening. Its association with diabetes is not uncommon and may influence the evolutionary profile. The aim of this study was to describe the profile of diabetic patients who could benefit from pancreatic cancer screening. Methods: we conducted a retrospective cross-sectional study in the gastroenterology department of the University Hospital of Brazzaville, from January 2010 to December 2019. Epidemiological variables (age, sex, alcoholism, smoking), tumor variables (symptoms, site, size, density, extension) and time of occurrence of both entities were analyzed using Epi info software. Results: A total of 35 patients were hospitalized for pancreatic cancer, of whom 17 were men and 15 women, for a sex ratio of 1.21. The mean age of the patients was 60.3 ± 13 years. Fifteen patients (43.75%) were diabetic, all classified as type 2. Among them, the diagnosis of diabetes of 10 patients (66.7%) preceded pancreatic cancer diagnosis and delay between the two pathologies was on average 3.4 years ± 5.3 months. Diabetes was observed in 11 patients older than 60 years. The difference was significant (OR = 4.8;95% CI [1.1a.> - 22.8];p = 0.0226). The other epidemiological variables studied were not related to the two pathologies. Conclusion:a. style="font-fa.ily:Verda.a."> we propose a.screening for pa.crea.ic ca.cer when dia.etes is discovered to pa.ients from 60 yea.s old, wha.ever their sex, especia.ly during the first 3 yea.s

关键词： Pa.crea.ic Ca.cer Dia.etes Mellitus a.socia.ion

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Hepa.ic Stea.osis in Pa.ients with Meta.olic Syndrome a. the Bra.za.ille University Hospita. Center

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Open Journa. of Ga.troenterology 2020年第6期10卷 119-127页

作者： Cla.sina.a.oui-a.endi Nga.a.a.oa.Itoua.Nga.oro a.na.d mongo-onkouo Moubié Ma.a.da.Merveille Jile Florient Mimiesse Nestor a.dzoua.a.Ba.a.ognoua.Régis Moyikoua.Rody Stépha.e Nga.i Nga.essa.i Moua.osso Ma.lyse Deby Ga.sa.e Bla.se Irénée a.ipo Iba.a.Iba.a.Jea.-Rosa.re Depa.tment of Ga.troenterology a.d Interna. Medicine CHU Brazzaville Brazzaville Congo Fa.ulty of Hea.th Sciences Marien Ngouabi University of Brazzaville Brazzaville Congo Depa.tment of Meta.olic a.d Endocrine Disea.es CHU Brazzaville Brazzaville Congo Ra.iology Depa.tment Brazzaville University Hospital Brazzaville Congo

Objective: To study the epidemiologica., clinica. a.d pa.a.linica. pa.ticula.ities of fa.ty liver disea.e in pa.ients with meta.olic syndrome. Pa.ients a.d Method: This wa. a.cross-sectiona. a.d a.a.ytica. study ca.ri... 详细信息

Objective: To study the epidemiological, clinical and paraclinical particularities of fatty liver disease in patients with metabolic syndrome. Patients and Method: This was a cross-sectional and analytical study carried out over a period of seven months, from February 1 to September 30, 2019, in the outpatient services of Gastroenterology and Metabolic and Endocrine Diseases of the Brazzaville University Hospital. It interested all patients with metabolic syndrome, according to the criteria of the FID harmonized in 2009, namely known diabetic and hypertensive patients, having abdominal obesity. Results: The variables studied were socio-demographic, clinical, morphological and biological. The search for fatty liver was done using an abdominal ultrasound. Results: During the study period, 124 patients with metabolic syndrome were included. The average age of the population was 52.8 ± 12 years with extremes ranging from 30 and 84 years. The population was mainly female with a Sex-Ratio of 2.54 (F/M). The frequency of fatty liver disease was 38.7%. The frequency of dyslipidemia was high in the study. Conclusion: The prevalence of hepatic steatosis is high in patients with metabolic syndrome at Brazzaville University Hospital. The gender, lack of occupation and high level of education were the factors associated with fatty liver disease.a.>a.>a.>

关键词： Fa.ty Liver Meta.olic Syndrome Bra.za.ille

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Epidemiologica. a.d Pa.a.linica. a.pects of Helicoba.ter pylori Infection a.ong Hepa.itis B Virus Ca.riers in the Republic of Congo

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Open Journa. of Ga.troenterology 2024年第5期14卷 184-191页

作者： Jile Florient Mimiesse Mona.ou Nuptia.Ka.oha.Elenga.Nga.a.Itoua.Nga.oro Cla.sina.a.oui a.endi Ma.lyse Nga.essa.i Moua.osso a.na.d mongo onkouo Ma.ria.Ibobi Rody Stépha.e Nga.i Ma.doché Motoula.La.ou Hosta.d a.ipo Iba.a.Céline Sa.dra.a.oua.Déby Ga.sa.e Bla.se Irénée a.ipo Iba.a Depa.tment of Ga.troenterology a.d Interna. Medicine Brazzaville University Hospital Brazzaville The Republic of Congo Fa.ulty of Hea.th Sciences Marien Ngouabi University Brazzaville The Republic of Congo

Objective: Describe the epidemiologica. a.d pa.a.linica. a.pects of HP infection in hepa.itis B virus ca.riers. Popula.ion a.d Method: This wa. a.descriptive cross-sectiona. study running from Ja.ua.y 1 to a.gust 30, 2019, a.period of 8 months. It took pla.e in the Hospita. Centers of the two ma.or cities of Congo (Bra.za.ille a.d Pointe-Noire). The ta.get popula.ion of our study consists of pa.ients ca.rying HBV under a.tivira. trea.ment or not. Pa.ients a.ed a. lea.t 18 yea.s a.d consenting with a.biologica. a.d morphologica. a.sessment were included. We did not include in our study pa.ients ta.ing or ha.ing ta.en a.tibiotics a.d/or PPIs less tha. 4 weeks a.o. We excluded a.l pa.ients who did not deposit fresh stools a.d those in whom stool extra.tion could not be done ma.ua.ly. The va.ia.les studied covered sociodemogra.hic, clinica. a.d pa.a.linica. a.pects. Da.a.entry wa. done using Excel 8.0 softwa.e. Sta.istica. a.a.ysis wa. ca.ried out with SPSS 20.0 softwa.e. Results: During our study, we included 169 pa.ients. The frequency of HPa. in the stools of HBV ca.riers in our study popula.ion wa. 63.9% (n = 109). Ma.e pa.ients represented 69% (n = 75) a.d fema.e pa.ients represented 31% (n = 34). The a.era.e a.e of the pa.ients is 43.92 ± 13.51 yea.s with extremes of 18 yea.s a.d 80 yea.s. Concerning profession, unemployed pa.ients a.d those working in the priva.e sector were the most represented in respectively 28.4% (n = 31) a.d 22.9% (n = 25) without sta.istica. link. Households comprising between 4 - 10 people a.d the use of public la.rines were the risk fa.tors most represented in respectively 69% (n = 75) a.d 88% (n = 96) without sta.istica. link. Clinica.ly, hepa.omega.y a.d signs of porta. hypertension were most represented in 53% (n = 58) a.d 47% (n = 51). Biologica.ly, HBV DNa.wa. detecta.le in 60.5% of ca.es (n = 66).

关键词： Helicoba.ter pylori Hepa.itis B Virus Congo

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Role of <i>Helicoba.ter pylori</i>Infection in Recurrent a.domina. Pa.n of the Child in Bra.za.ille

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Open Journa. of Pedia.rics 2020年第4期10卷 587-599页

作者： Olla.dzobo Ikobo Lucie Cha.lotte a.ombo Niotsebe Lydie Bénédicte mongo-onkouo a.na.d a.oui a.endi Cla.sina.Rochelvie Itoua.Nga.oro Nga.a.a.oa.Mimiesse Mouna.ou Jile Florent Tchidjo Nga.o Lynda.Déby Ga.sa.e Ma.ia.a.Ba.ela.Jea. Robert a.ipo Iba.a.Bla.se Irénée Iba.a.Jea.-Rosa.re Fa.ulty of Hea.th Sciences Marien Ngouabi University of Brazzaville Brazzaville Congo Infa.ts Pedia.ric wa.d Brazzaville University Teaching Hospital Brazzaville Congo Ga.troentérology a.d Interna. Medicine Wa.d Brazzaville University Teaching Hospital Brazzaville Congo

The Helicoba.ter pylori (Hp) infection is a.public hea.th problem, especia.ly in developing countries. However, the responsibility of Hp for the occurrence of recurrent a.domina. pa.n is still unclea.. Objectives: To ... 详细信息

The a.>Helicobacter pylori (Hp) infection is a public health problem, especially in developing countries. However, the responsibility of Hp for the occurrence of recurrent abdominal pain is still unclear. Objectives: To determine the prevalence of Helicobacter pylori (Hp) infection in children with recurrent abdominal pain (RAP) in Brazzaville and to establish the relationsa.>hip between Hp infection and RAP. Patients and Methods: We conducted a cross-sectional case-control study, between March and September 2018, including 106 children with RAP and 218 children without RAP, aged 2 to 17 years old, received in health centres in Brazzaville. All the children were subjected to detection of Hp fecal antigen by qualitative immuno-chromatography in the faeces. Results:a. style="font-fa.ily:Verda.a."> The preva.ence of Hp infection a.ong children with Ra. in Bra.za.ille wa. 43.4%. The fema.e sex wa. most represented in both popula.ions, with a.sex ra.io of 0.84 in the infected popula.ion. Compa.ed with controls, these were children with a.mea. a.e of 8.13 ± 4.57 yea.s. Infected children with Ra. were unschooled in 66.7% (n = 31) of ca.es (p a.dwa.hing before mea.s a.d a.ter using the toilet wa. not done in 66.7% (n = 31) a.d 56.5%

关键词： Helicoba.ter pylori Recurrent a.domina. Pa.n Feca. a.tigen Child Bra.za.ille

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Recurrent Iron Deficiency a.emia.Revea.ing Chronic Ga.tritis with <i>Helicoba.ter pylori</i>

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Open Journa. of Ga.troenterology 2021年第2期11卷 47-51页

作者： Jile Florient Mimiesse Nga.a.Itoua.Nga.oro a.na.d mongo onkouo Cla.sina.a.oui a.endi Lucie a.ipo Iba.a.Olla.dzobo Ma.lyse Nga.essa.i Moua.osso Ma.doché Perez Motoula.Rody Stépha.e Nga.i Sa.dra.Celine a.oua.Firmin Bossa.i Deby Ga.sa.e Bla.se Irénée a.ipo Iba.a.Jea.-Rosa.re Iba.a Fa.ulty of Hea.th Sciences Marien Ngouabi University Brazzaville Congo Depa.tment of Ga.troenterology a.d Interna. Medicine University Hospital of Brazzaville Brazzaville Congo

We report a.clinica. ca.e of a.21-yea.-old pa.ient with iron deficiency a.emia.rela.ed to Helicoba.ter pylori (H. pylori) infection. The pa. ga.tritis due to H. pylori a.d a. unexpla.ned iron deficiency a.emia.ha. recently been proposed a.though still discussed. a.ong the possible ca.ses the role pla.ed by this ba.terium rema.ns controversia.. The dia.nosis ha. been mentioned in view of the recurrence of a.emia.a.d confirmed by endoscopic biopsy. a.emia.wa. corrected by iron supplementa.ion a.socia.ed with a.specific trea.ment of this germ.

关键词： Iron Deficiency a.emia Helicoba.ter pylori Pa.ga.tritis

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