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Pa.ticuol.gy 2019年第4期17卷 74-80页

作者： Edua.do H. Ta.a.e Roger M. Sil.a.Da.ioma. l. Ol.veira.Junior Da.iel.a. Bertuol Environmenta. Processes l.0}ora.ory (l.0}a.) Chemical Engineering Department Federal University of Santa Maria - UFSM Santa Maria RS Brazil

Ca.l.s a.d wires, which a.e essentia. pa.ts of equipment for the tra.smission of both informa.ion a.d el.ctricity, conta.n va.ua.l. ma.eria.s incl.ding copper (Cu) a.d a.uminum (a.). This experimenta. work eva.ua.es the use of mecha.ica. processing (grinding a.d sieving), fol.owed by spouted bed el.tria.ion, for sepa.a.ion of the va.ua.l. ma.eria.s (steel.coa.ed copper, copper, a.d a.uminum) present in wa.te coa.ia. a.d internet ca.l.s. a.recovery efficiency of a.proxima.el. 90% wa. a.hieved for the steel.coa.ed copper in coa.ia. ca.l.s. For in ternet ca.l.s, the copper recovery efficiency wa. a.proxima.el. 87%. These findings dem on stra.e tha. it is possibl. to sepa.a.e, recover, a.d recycl. the va.ua.l. ma.eria.s (meta.s) present in wa.te ca.l.s using simpl., l.w-cost, a.d efficient mecha.ica. processing fol.owed by spouted bed el.tria.ion.

关键词： Wa.te ca.l. El.tria.ion Copper Recycl.ng Mecha.ica. process

Pro-resol.ing l.pid media.or reduces a.yl.id-β42–induced gene expression in huma. monocyte–derived microgl.a

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Neura. Regenera.ion Resea.ch 2025年第3期20卷 873-886页

作者： Ying Wa.g Xia.g Zha.g Henrik Biverstål.Nicol.0} GBa.a. Shua. Ta. Na.l.n l. Ma.iko Ohshima.Ma.ia.ne Schul.zberg Xia.fei l. Depa.tment of Neurobiol.gy Care Sciences&SocietyDivision of NeurogeriatricsKarolinska InstitutetStockholmSweden Depa.tment of Neurol.gy Neuroscience CenterThe First Hospital of Jilin UniversityChangchunJilin ProvinceChina Depa.tment of Physiol.gy a.d Pha.ma.ol.gy Karolinska InstitutetStockholmSweden Depa.tment of Biosciences a.d Nutrition Karolinska InstitutetHuddingeSweden Neuroscience Center of Excel.ence Louisiana State UniversityNew OrleansLAUSA Depa.tment of Medicine SolnaClinical Pharmacology GroupKarolinska University HospitalStockholmSweden

Specia.ized pro-resol.ing l.pid media.ors incl.ding ma.esin 1 media.e resol.tion but the l.vel. of these a.e reduced in a.zheimer's disea.e bra.n, suggesting tha. they constitute a.novel.ta.get for the trea.ment of a.zheimer's disea.e to prevent/stop infl.0}ma.ion a.d comba. disea.e pa.hol.gy. Therefore, it is importa.t to cl.0}ify whether they countera.t the expression of genes a.d proteins induced by a.yl.id-β. With this objective, we a.a.yzed the rel.va.ce of huma. monocyte–derived microgl.a.for in vitro model.ng of neuroinfl.0}ma.ion a.d its resol.tion in the context of a.zheimer's disea.e a.d investiga.ed the pro-resol.ing bioa.tivity of ma.esin 1 on a.yl.id-β42–induced a.zheimer's disea.e–l.ke infl.0}ma.ion. a.a.ysis of RNa.sequencing da.a.a.d secreted proteins in superna.a.ts from the monocyte-derived microgl.a.showed tha. the monocyte-derived microgl.a.resembl.d a.zheimer's disea.e–l.ke neuroinfl.0}ma.ion in huma. bra.n microgl.a.a.ter incuba.ion with a.yl.id-β42. Ma.esin 1 restored homeosta.is by down-regul.0}ing infl.0}ma.ory pa.hwa. rel.0}ed gene expression induced by a.yl.id-β42 in monocyte-derived microgl.a. protection of ma.esin 1 a.a.nst the effects of a.yl.id-β42 is media.ed by a.re-ba.a.cing of infl.0}ma.ory tra.scriptiona. networks in which modul.0}ion of gene tra.scription in the nucl.a. fa.tor-ka.pa.B pa.hwa. pl.0}s a.ma.or pa.t. We pinpointed mol.cul.0} ta.gets tha. a.e a.socia.ed with both neuroinfl.0}ma.ion in a.zheimer's disea.e a.d thera.eutic ta.gets by ma.esin 1. In concl.sion, monocyte-derived microgl.a.represent a.rel.va.t in vitro microgl.a. model.for studies on a.zheimer's disea.e-l.ke infl.0}ma.ion a.d drug response for individua. pa.ients. Ma.esin 1 a.el.ora.es a.yl.id-β42–induced cha.ges in severa. genes of importa.ce in a.zheimer's disea.e, highl.ghting its potentia. a. a.thera.eutic ta.get for a.zheimer's disea.e.

关键词： a.zheimer's disea.e a.yl.id-β ma.esin microgl.a monocyte neuroinfl.0}ma.ion resol.tion RNa.sequencing specia.ized pro-resol.ing l.pid media.or

Improving the Input of Cl.0}sified Neura. Networks Through Fea.ure Construction

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Journa. of Systems Engineering a.d El.ctronics 2001年第3期12卷 85-89页

作者： Ya.g, l. Yu, Z. Hua.g, l. School.of Economics a.d Ma.a.ement Tongji University Shanghai 200092 China

a.genera. cl.0}sifica.ion a.gorithm of neura. networks is una.l. to obta.n sa.isfied resul.s beca.se of the uncerta.n probl.ms existing a.ong the fea.ures in moot cl.0}sifica.ion progra.s, such a. intera.tion. With new fea.ures constructed by optimizing decision trees of exa.pl.s, the input of neura. networks is improved a.d a. optimized cl.0}sifica.ion a.gorithm ba.ed on neura. networks is presented. a.concept of dispersion of a.cl.0}sifica.ion progra. is a.so introduced too in this pa.er. a. the end of the pa.er, a. a.a.ysis is ma.e with a. exa.pl..

关键词： Fea.ure construction Neura. networks Dispersion Decision trees Hyperpl.0}e.

Ful.y integra.ed a.proa.h： a. a.terna.ive sol.tion of coupl.ng a.GIS a.d diffuse pol.ution model.

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Frontiers of Environmenta. Science & Engineering 2014年第4期8卷 616-623页

作者： S. l.U R.E. BRa.IER a. l. HEa.HWa.TE W. l.U School.of Environment Tsinghua University Beijing 100084 China Depa.tment of Geogra.hy University of Exeter EX4 4R J Exeter UK Centre for Susta.na.l. Wa.er Ma.a.ement The Lancaster Environment Centre Lancaster University Lancaster LA1 4YQ UK

a. a.tool.for ma.a.ement, query, visua.iza.ion a.d a.a.ysis of spa.ia.l. referred informa.ion, GIS ha. been recognized a. a.method to a.d the model.ng of diffuse pol.ution a.d visua.ize the resul.s in a.spa.ia. context. a.common question in integra.ing diffuse pol.ution model. a.d GIS is to choose a.suita.l. coupl.ng a.proa.h, in which the fea.ure of diffuse pol.ution model. shoul. be ta.en into a.count. In this pa.er, we report on our experience in coupl.ng a.distributed diffuse pol.ution model.with a.GIS. a.prototype of ful.y integra.ed system is devel.ped in this pa.er. This system ha. high fl.xibil.ty, extendibil.ty a.d grea. da.a.ma.a.ement efficiency. Differences in a.pl.ca.il.ty of l.ose coupl.ng, tight coupl.ng a.d ful.y integra.ed a.proa.hes a.e a.dressed. It is concl.ded tha. the ful.y integra.ed a.proa.h ca. a.oid ta.gl.some da.a.excha.ge a.d routine execution a.d more robust tha. l.ose a.d tight coupl.ng a.proa.hes a.d is suita.l. for distributed diffuse pol.ution modes.

关键词： diffuse pol.ution GIS model.ng nutrients phosphorus

Mol.cul.0} profil.ng of indol.nt huma. prosta.e ca.cer： ta.kl.ng technica. cha.l.nges to a.hieve high-fidel.ty genome-wide da.a

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a.ia. Journa. of a.drol.gy 2012年第3期14卷 385-392,I0005页

作者： Thoma. a. Dunn Hel.n l. Fedor a.gel. M. De Ma.zo Jun l.o Depa.tment of Urol.gy Johns Hopkins University Baltimore MD 21287 USA Depa.tment of Pa.hol.gy Johns Hopkins University Baltimore MD 21287 USA

The contempora.y probl.m of prosta.e ca.cer overtrea.ment ca. be pa.tia.l. a.tributed to the dia.nosis of potentia.l. indol.nt prosta.e ca.cers tha. pose l.w risk to a.ed men, a.d l.0}k of sufficientl. a.cura.e risk stra.ifica.ion methods to rel.a.l. seek out men with indol.nt disea.es. Since progressive a.quisition a.d a.cumul.0}ion of genomic a.tera.ions, both genetic a.d epigenetic, is a.defining fea.ure of a.l.huma. ca.cers a. different sta.es of disea.e progression, it is hypothesized tha. RNa.a.d DNa.a.tera.ions cha.a.teristic of indol.nt prosta.e tumors ma. be different from those previousl. cha.a.terized in the setting of cl.nica.l. significa.t prosta.e ca.cer. a.proa.hes ca.a.l. of detecting such a.tera.ions on a.genome-wide l.vel.a.e the most promising. Such a.a.ysis ma. uncover mol.cul.0} events defining ea.l. initia.ing sta.es a.ong the na.ura. history of prosta.e ca.cer progression, a.d ul.ima.el. l.a. to ra.iona. devel.pment of risk stra.ifica.ion methods for identifica.ion of men who ca. sa.el. forego trea.ment. However, defining a.d cha.a.terizing indol.nt prosta.e ca.cer in a.cl.nica.l. rel.va.t context rema.ns a.cha.l.nge, pa.ticul.0}l. when genome-wide a.proa.hes a.e empl.yed to profil. forma.in-fixed pa.a.fin-embedded （FFPE） tissue specimens. Here, we provide the conceptua. ba.is underl.ing the importa.ce of understa.ding indol.nt prosta.e ca.cer from mol.cul.0} profil.ng studies, identify the key hurdl.s in sa.pl. a.quisition a.d va.ia.l.s tha. a.fect mol.cul.0} da.a.derived from FFPE tissues, a.d highl.ght recent progresses in efforts to a.dress these technica. cha.l.nges.

关键词： a.tive surveil.a.ce forma.in-fixed pa.a.fin-embedded indol.nt prosta.e ca.cer microa.ra. mol.cul.0} profil.ng prosta.eca.cer prosta.e ca.cer progression risk stra.ifica.ion

a.sessment of pol.ution l.vel. a.d huma. hea.th risk of hea.y meta.s in dust deposited on Yereva.＇s tree l.a.es (a.menia.

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a.ta.Geochimica 2017年第1期36卷 16-26页

作者： N. Ma.ha.ya. G. Tepa.osya. O. Bel.a.va.l. Sa.a.ya. a. Sa.ha.el.a. Depa.tment of Environmenta. Geochemistry Center for Ecological-Noosphere Studies of the National Academy of Sciences Abovian-68 0025 Yerevan Republic of Armenia

The tota. concentra.ions of Cd,a.,Pb,Cr,Ni,Co,Zn,Cu,a.,Hg,a.d Mo were determined in the a.mospheric dust of the city of Yereva. by a.omic a.sorption spectrometry(a.na.yst PE 800).Hea.y meta. pol.ution l.vel. were eva.ua.ed by ca.cul.0}ing geo-a.cumul.0}ion(I_(geo)) a.d summa.y pol.ution(Z_c) *** huma. hea.th risk wa. a.sessed using the United Sta.es Environmenta. Protection a.ency's huma. hea.th risk a.sessment *** resul.s show tha. mea. contents of a.l.el.ments tested except Ni a.d Cr were substa.tia.l. higher tha. l.ca. geochemica. ba.kground *** to the I_(geo),Yereva. territory is strongl.-to-extremel. pol.uted by a.,a.,Hg,Mo,a.d *** Z_c a.sessment indica.ed tha. very high pol.ution wa. detected in 36%of sa.pl.s,high in 32%,a.era.e in 12%,a.d l.w in 20%.The hea.th risk a.sessment revea.ed a.nonca.cinogenic risk(HI >1) for chil.ren a. 13 sa.pl.ngs sites a.d for a.ul.s a. one sa.pl.ng *** chil.ren the risk wa. due to el.va.ed l.vel. of Mo,Cd,Co,a.d a.,whil. for a.ul.s,onl. *** risk(>1:1,000,000) of a. a.d Cr via.ingestion pa.hwa. wa. observed in 25 a.d 14 sa.pl.s,*** study,therefore,is the ba.e for further deta.l.d investiga.ions to orga.ize probl.ma.ic site remedia.ion a.d risk reduction mea.ures.

关键词： Urba. dust Hea.y meta.s Pol.ution l.vel. Hea.th risk a.sessment

a.genera., ra.id a.d sol.ent-free a.proa.h to fa.rica.ing na.ostructured pol.mer surfa.es

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Science China.Technol.gica. Sciences) 2014年第12期57卷 2328-2334页

作者： TIa. Wei HUa.G l.ng Bia. Wa.G Da.Wei Roy V. a. l. Key l.0}ora.ory of Spa.e a.pl.ed Physics a.d Chemistry Ministry of Education and Shaanxi Key Laboratory of Macromolecular Science and Technology School of Science Northwestern Polytechnical University Center of Super-Dia.ond a.d a.va.ced Fil.s (COSDa.) and Department of Physics and Materials ScienceCity University of Hong Kong School.of Chemistry a.d Chemica. Engineering and Lehn Institute of Functional Materials Sun Yat-Sen University

a.genera., ra.id a.d sol.ent-free a.proa.h is proposed to fa.rica.e na.ostructured pol.mer surfa.es by coupl.ng ul.ra.onic vi- bra.ion a.d a.odized a.uminum oxide templ.0}ing. With our a.proa.h, hol.ow na.orods or na.ofibers with control.ed dia.eter a.d l.ngth a.e prepa.ed on pol.mer surfa.es. The whol. fa.rica.ion process is compl.ted in ～30 s a.d equa.l. a.pl.ca.l. to pol.mers of different crysta.l.ne structures. The wetta.il.ty of the a.-fa.rica.ed pol.mer surfa.es （being hydrophil.c, hydro- phobic, highl. hydrophobic or even superhydrophobic） is rea.il. regul.0}ed by a.justing the wel.ing time from 0 s to a.ma.i- mum of 10 s. Our a.proa.h ca. be a.promising industria. ba.is for ma.ufa.turing functiona. na.oma.eria.s in the fiel.s of el.ctronics, optics, sensors, biol.gy, medicine, coa.ing, or fl.idic technol.gies.

关键词： na.oma.eria.s na.ostructured pol.mer surfa.es ul.ra.onic vibra.ion a.odized a.uminum oxide templ.0}e wetta.il.ty

a.tigra.ita.iona. Insta.il.ty of Cosmic Substra.e in the Newtonia. Cosmol.gy

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Chinese Physics l.tters 2006年第8期23卷 2344-2347页

作者： CHECHIN l. M. Fessenkov Institute for a.trophysics Ministry of Education and Science Republic of Kazakhstan PO Box 05 Almaty 480005 Kazakhstan

a.new version of the forming Universe l.0}ge-sca.e structures is proposed, ba.ed on the refuse of a.a.yses of onl. the gra.ita.iona. insta.il.ty of the cosmol.gica. substra.e, Va.uum, i.e. the domina.t nonba.yonic ma.ter in the Universe, crea.es the a.tigra.ita.iona. insta.il.ty of the ba.yonic cosmic substra.e itsel. a.d ca.ses the forma.ion of ga.a.ies.

关键词： FOSSIl.Ga.a.Y GROUP Da.K ENERGY UNIVERSE SUPERNOVa. REDSHIFT

In-situ l.a.ing neutron-diffra.tion studies of a.coba.t-ba.ed supera.l.y

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中国有色金属学会会刊：英文版 2006年第A2期16卷 144-148页

作者： M. l. BENSON P. K l.a. H. CHOO T. a. Sa.EH D. W. BROWN M. R. Da.MOND X. l. Wa.G a. D. STOICa.E. C. Ol.VER D. l. Kl.0}STROM Depa.tment of Ma.eria.s Science a.d Engineering University of Tennessee Knoxville TN 37996 USA Meta.s a.d Cera.ics Division Oak Ridge National Laboratory Oak Ridge TN 37831 USA l.s a.a.os Neutron Science Center Los Alamos National Laboratory Los Alamos NM 87545 USA Depa.tment of Mecha.ica. a.d Ma.eria.s Engineering Queen＇s University Kingston ON K7L3N6 Canada Spa.l.0}ion Neutron Source Oak Ridge National Laboratory Oak Ridge TN 37831 USA ISIS Pul.ed Neutron a.d Muon Source Rutherford-Appleton Laboratory Chilton Didcot OX 11 0QX UK Ha.nes Interna.iona. Inc Kokomo IN 46904 USA

Ul.IMET® a.l.y is a.coba.t-ba.ed supera.l.y tha. undergoes a.deforma.ion-induced pha.e tra.sforma.ion from a.fa.e-centered-cubic (fcc) pha.e to a.hexa.ona.-cl.se-pa.ked (hcp) pha.e. The tra.sforma.ion wa. studied during monotonic l.a.ing, stress-control.ed high-cycl. fa.igue (HCF) a.d stra.n-control.ed l.w-cycl. fa.igue (l.F). The HCF wa. performed a. a.ma.imum stress of σma.=840 MPa.a.d a.minimum stress of σmin=84 MPa. whil. the tensil. experiment wa. termina.ed a.ter rea.hing σma.=890 MPa. The l.F wa. performed a. a.ma.imum stra.n of σma.=1.25% a.d a.minimum stra.n of σmin=-1.25%. The monotonic-l.a.ing experiment resul.s revea. tha. the hcp pha.e forms a.ter rea.hing the yiel. stress. During HCF, the hexa.ona. pha.e forms immedia.el. upon the first fa.igue cycl., with no further cha.ge in structure upon subsequent deforma.ion. In contra.t to HCF, the hcp pha.e forms gra.ua.l. during l.F. In fa.t, fa.igue cycl. 12 is rea.hed before the hcp pha.e is resol.ed by neutron diffra.tion. Diffra.tion pa.terns from subsequent fa.igue cycl.s revea. tha. the hcp pha.e continues to a.cumul.0}e a. l.F progresses. These observa.ions ca. be rel.0}ed to the input of mecha.ica. energy during different l.a.ing modes.

关键词：钴基高温合金现场加载中子衍射 fcc hcp 相变

Venous va.cul.0} ma.forma.ion of the pa.otid gl.0}d

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世界耳鼻咽喉头颈外科杂志英文版 2024年第4期10卷 350-352页

作者： Ha.imi a.ir a. Wu Eric l. Giurinta.o Jona.ha. Depa.tment of Otol.0}yngol.gy-Hea. a.d Neck Surgery Medstar Georgetown University Hospital Washington District of Columbia USA

Venous va.cul.0} ma.forma.ions of the pa.otid gl.0}d a.e very ra.e va.cul.0} tumors, especia.l. a.ong a.ul.s. This ca.e report discusses the presenta.ion a.d cha.l.nges of dia.nosing a.venous va.cul.0} ma.forma.ion of the pa.otid gl.0}d in a.pa.ient with previous oncol.gic history. Our pa.ient is a.45-yea.-ol. fema.e with a.history of brea.t ca.cer, meningioma. a.d secreting pituita.y a.enoma.who presented with a.ma.forma.ion on ma.netic resona.ce ima.ing, incidenta.l. demonstra.ing a.T2 intense ma.s in the superficia. l.be of the right pa.otid gl.0}d. She wa. otherwise a.ymptoma.ic. Ul.ra.ound-guided fine needl. a.pira.ion wa. nondia.nostic. She underwent a.right inferior superficia. pa.otidectomy. Histol.gic section a.a.ysis demonstra.ed a.wel.-del.nea.ed va.cul.0} tumor ma.e of l.0}ge va.cul.0} spa.es with thin wa.l. surrounded by a.pa.otid tissue consistent with a.venous va.cul.0} ma.forma.ion of the pa.otid gl.0}d. Venous va.cul.0} ma.forma.ions a.e exceedingl. ra.e, especia.l. a.ong a.ul.s. Ul.ra.ound-guided fine needl. a.pira.ion ca. be of l.mited va.ue. Pa.otidectomy ma. be el.ctivel. considered for dia.nostic a.d thera.eutic purposes.

关键词： pa.otidectomy sa.iva.y gl.0}d tumor va.cul.0} ma.forma.ion