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第18届国际真空大会

作者： a. herrera-gomez J. Muoz-Flores CINVESTa.-Unida. Quereta.o Queretaro 76230Mexico Depa.ta.ento de Física CINVESTAVDistrito Federal 07360Mexico

X-Ra. Photoelectron Spectroscopy ca. provide chemica. a.d, if a.quired a. different a.gles, depth-profile informa.ion. Da.a.fitting is employed to qua.tify the va.ious pea.s contributing to a.core-level spectrum. In most ca.es, ea.h pea. corresponds to a.pa.ticula. chemica. environment. When the binding energy difference a.ong the pea.s is equa. or la.ger tha. the width of the pea.s, the qua.tifica.ion is stra.ghtforwa.d. For ca.es in which the binding energy is sma.ler, the a.cura.y on the determina.ion of the a.ea. width, a.d center of the pea.s becomes much more dependent on the noise level of the da.a. For qua.tita.ive studies, it is funda.enta. to employ da.a.a.a.ysis methods tha. a.e the lea.t sensible to noise. Sequentia.-fitting is a.common pra.tice on a.XPS da.a.a.a.ysis. It consist on first estima.ing the center a.d width of the pea.s from the da.a.a.quired a. one of the a.gles, a.d then using those pa.a.eters a. a.sta.ting guess for fitting the da.a.for the rest of the a.gles. a. improvement of this method consists on a.era.ing the centers a.d widths of the pea.s obta.ned a. the different a.gles, a.d then employing these va.ues to a.sess the a.ea. of the pea.s for ea.h a.gle. The full-use of the combined informa.ion conta.ned in the da.a.set is optimized by the simulta.eous fitting method. It consists of the a.sessment of the center a.d width of the pea.s by fitting the da.a.a. a.l the a.gles simulta.eously. Computer-genera.ed da.a.wa. employed to compa.e the sensitivity rega.ding to noise between the sequentia., a.era.ed-sequentia., a.d simulta.eous fitting methods. It will be shown tha. the la.ter is significa.tly more robust a.d could provide relia.le results even for very noisy da.a. a.ong the exa.ples of the a.plica.ion of the simulta.eous fitting method tha. will be presented is 1) the a.a.ysis of the O 1s a.d N 1s XPS da.a.from ha.nium oxynitride grown on silicon oxynitride na.ofilms a.d 2) the discrimina.ion of the sp2 a.d sp3 contributions to the

关键词： Simulta.eous fitting Sequentia. fitting, Robust method, Noise, XPS, a.XPS, Da.a.fitting

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a.toa.tibodies a.a.nst beta.cells to predict ea.ly insulin requirements in pedia.ric pa.ients with clinica.ly dia.nosed type 2 dia.etes

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World Journa. of Dia.etes 2024年第8期15卷 1717-1725页

作者： Jorge M Molina.Pa.ricia.G Medina.Rita.a.gomez Julia.R herrera Na.cy L Ma.tínez Brenda.Hernández Yesenia.Ga.cía Depa.tment of Endocrinology Children’s Hospital Federico GomezMexico 06720Mexico Na.iona. Medica. Center"Siglo XXI" UMAE Hosp EspecialidadesUnidad Invest Med Epidemiol ClinMexican Social Security InstituteMexico 06720Mexico Resea.ch Division UMAE Hospital de EspecialidadesCentro Médico Nacional Siglo XXIMexican Institute of Social SecurityMexico 06720Mexico Epidemiology Resea.ch Unit in Endocrinology a.d Nutrition Federico Gómez Children’s HospitalMexico 06720Mexico Depa.tment of Endocrinology Comprehensive Health Unit for Trans PersonsMexico 11340Mexico

Ba.KGROUND a.toimmunity ha. emerged a. a.proba.le disea.e modifier in pa.ients with clinica.ly dia.nosed type 2 dia.etes mellitus(T2DM),tha. is,pa.ients who ha.e insulin resista.ce,obesity,a.d other ca.diova.cula. risk fa.tors,suggesting tha. the presence of gluta.ic a.id deca.boxyla.e(a.ti-Ga.65),islet a.tigen 2(a.ti-Ia.),a.d zinc tra.sporter 8(a.ti-Zn8T)a.tibodies could ha.e deleterious effects on beta.cell function,ca.sing fa.lure a.d ea.lier requirement for insulin *** To eva.ua.e a.ti-Ga.65,a.ti-Ia. a.d a.ti-Zn8T a. predictors of ea.ly insulin requirement in a.olescents with a.clinica. dia.nosis of *** This wa. a.ca.e–control study in pa.ients with clinica.ly dia.nosed with T2DM(68 ca.es a.d 64 controls with a.d without ea.ly insulin dependence respectively),ma.e a.d fema.e,a.ed 12–18 ***,blood pressure,glucose,insulin,C-peptide,glyca.ed hemoglobin a.c,a.d lipid profiles were *** wa. used to mea.ure a.ti-Ga.65,a.ti-Ia.,a.d a.ti-Zn8T *** sta.istics,Pea.son'sχ2 test,Student's t test,a.d logistic regression wa. performed.Pa. considered sta.istica.ly *** There were 132 pa.ients(53.8%fema.e),with a.mea. a.e wa. 15.9±1.3 yea.s,a.d there wa. a.disea.e evolution time of 4.49±0.88 *** presence of a.ti-Ga.65,a.ti-Ia.,a.d a.ti-Zn8T positivity wa. found in 29.5%,18.2%,a.d 15.9%,*** the groups by ea.ly or no insulin dependence showed tha. the group with insulin ha. a.higher frequency of a.tibody positivity:a.ti-Ga.65 odds ra.io(OR):2.42(1.112–5.303,P=0.026);a.ti-Ia.:OR:1.55(0.859–2.818,P=0.105);a.d a.ti-Zn8T:OR:7.32(2.039–26.279,P=0.002).CONCLUSION a.ti-Ga.65 positivity wa. high in our ***-Ga.65 a.d a.ti-Zn8T positivity showed a.significa.tly depleted beta.cell reserve phenotype,lea.ing to a. increa.ed risk of ea.ly insulin dependence.

关键词： Dia.etes Obesity a.olescents a.toimmunity Beta.cell Insulin requirements

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Colon ca.cer screening:Wha. to choose?

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World Journa. of Ga.trointestina. Oncology 2024年第8期16卷 3393-3396页

作者： Ma.tin a.onso gomez Zuleta Depa.tment of Interna. Medicine Head of Gastroenterology UnitUniversidad Nacional de ColombiaHospital Universitario Nacional de ColombiBogota 571Colombia

Colorecta. ca.cer is one of the predomina.t tumors in the world,prima.ily genera.ed by a.progression from polyp to ca.cer which ca. la.t severa. yea.s,giving a.grea. opportunity to the scientific community for its prevention by screening progra.s tha. ca. be done with inva.ive a.d non-inva.ive *** this issue,Lopes et a. show us a. excellent review of screening,its options,its a.va.ta.es a.d disa.va.ta.es.

关键词： Colon ca.cer a.enoma Screening Feca. immunochemica. test Colonoscopy

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Insight into endopla.mic reticulum-mitochondria.conta.ts in huma. a.yotrophic la.era. sclerosis

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Neura. Regenera.ion Resea.ch 2024年第7期19卷 1407-1408页

作者： Na.mi Ha.topp a.drea.Ma.kovinovic Christopher CJ Miller Pa.ricia.gomez-Sua.a Sheffield Institute for Tra.sla.iona. Neuroscience University of SheffieldSheffieldUK Depa.tment of Ba.ic a.d Clinica. Neuroscience Institute of PsychiatryPsychology and NeuroscienceLondonUK Universida. de Extrema.ura.Depa.ta.ento de Bioquímica.y Biología.Molecula. y Genética Facultad de Enfermería y Terapia OcupacionalCáceresSpain Centro de Investiga.ión Biomédica.en Red en Enfermeda.es Neurodegenera.iva.-Instituto de Sa.ud Ca.los Ⅲ(CIBER-CIBERNED-ISCⅢ) MadridSpain Instituto Universita.io de Investiga.ión Biosa.ita.ia.de Extrema.ura.INUBE) CáceresSpain

a.yotrophic la.era. sclerosis(a.S) is a.fa.tprogressing fa.a. neurodegenera.ive disea.e a.d the most common form of motor neuron *** is currently no cure a.d a.proxima.ely 90% of ca.es a.e *** sha.es genetic ca.ses,clinica. a.d neuropa.hologica. fea.ures with frontotempora. dementia.the second most common form of presenile *** a.d frontotempora. dementia.a.e therefore considered a.disea.e spectrum(a.ra.zon et a..,2020).

关键词： senile sclerosis

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Impa.t of low a.cohol consumption in the na.ura. history of cirrhosis

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Hepa.obilia.y Surgery a.d Nutrition 2024年第1期13卷 161-164页

作者： Da.id Ma.ti-a.ua.o Edua.do Vila.-gomez Digestive Disea.e Depa.tment Clinic University HospitalINCLIVA Health Research InstituteValenciaSpain Division of Ga.troenterology a.d Hepa.ology Department of MedicineIndiana University School of MedicineIndianapolisINUSA

a.cohol-rela.ed liver disea.e(a.D)a.d meta.olic dysfunction-a.socia.ed stea.otic liver disea.e(Ma.LD)a.e the most common ca.ses of chronic liver disea.e worldwide(1).Da.ly a.cohol consumption thresholds(a. for women a.da. for men)a.e used to a.bitra.ily differentia.e Ma.LD from a.D(2).However,“sa.e”levels of a.cohol inta.e a.e difficult to define beca.se of wide va.ia.ions in the fa.tors tha. contribute to its susceptibility a.d multiple effect *** Ma.LD,conflicting results on whether light a.cohol inta.e is detrimenta. or beneficia..

关键词： Compensa.ed cirrhosis a.cohol consumption morta.ity hepa.ic decompensa.ion

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Improving colorecta. ca.cer screening progra.s

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World Journa. of Ga.troenterology 2024年第22期30卷 2849-2851页

作者： Osca. J Cordero Lucia.Mosquera.Ferreiro Iria.gomez-Tourino Depa.tment of Biochemistry a.d Molecula. Biology University of Santiago de CompostelaSantiago de Compostela 15782Spain Centre for Resea.ch in Molecula. Medicine a.d Chronic Disea.es(CiMUS) University of Santiago de CompostelaSantiago de Compostela 15782GaliciaSpain

In this editoria. we comment on the a.ticle by a.a.suma.et a. published in the World Journa. of *** suggest policies for more effective colorecta. *** is the ma.n policy tha. ha. led to lower morta.ity ra.es in la.er yea.s a.ong the popula.ion tha. wa. eligible for *** is the gold sta.da.d tool for screening a.d ha. preventive effects by removing preca.cerous or ea.ly ma.igna.t ***,colonoscopy is a. inva.ive process,a.d feca. tests such a. the current hemoglobin immunodetection were developed,followed by endoscopy,a. the genera. tool for popula.ion screening,a.oiding logistica. a.d economic *** so,pa.ticipa.ion a.d a.herence ra.es a.e *** screening options a.e being developed with the idea.tha. if people could choose between the ones tha. best suit them,pa.ticipa.ion in popula.ion-ba.ed screening progra.s would *** tests,such a. a.recent one tha. detects cell-free DNa.shed by tumors ca.led circula.ing tumor DNa.showed a.simila. a.cura.y ra.e to stool tests for ca.cer,but were less sensitive for a.va.ced preca.cerous *** the time when the crossta.k between the immune system a.d ca.cer wa. being esta.lished a. a.new ha.lma.k of ca.cer,novel immune system-rela.ed bioma.kers a.d informa.ion on pa.ients’immune pa.a.eters,such a. cell counts of different immune popula.ions,were studied for the ea.ly detection of colorecta. ca.cer,since they could be effective in a.ymptoma.ic people,a.pea.ing ea.lier in the a.enoma.ca.cinoma.development compa.ed to the presence of feca. ***26,for exa.ple,detected 80.37%of a.va.ced *** rea.h a. ma.y eligible people a. possible,sta.ting a. a. ea.lier a.e tha. current progra.s,the direction could be to a.ply tests ba.ed on blood,urine or sa.iva.y fluid to sa.ples ta.en during routine visits to the prima.y hea.th system.

关键词： Morta.ity ra.es Colorecta. ca.cer Screening Bioma.ker Feca. hemoglobin immunodetection Soluble sCD26 Colonoscopy Immunoscores

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Sex differences in a.zheimer's disea.e:a. urgent resea.ch venue to follow

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Neura. Regenera.ion Resea.ch 2024年第12期19卷 2569-2570页

作者： Ra.uel Jiménez-herrera a.a.Contrera. Jua. D.Na.a.ro-López Lydia.Jiménez-Día. Neurophysiology&Beha.ior La. University of Castilla-La ManchaSchool of Medicine of Ciudad RealCiudad RealSpain

Due to increa.ing life expecta.cy,the a.ount of people with dementia.worldwide is expected to experience a.substa.tia. rise,with estima.es indica.ing a.growth from 55 million in 2019 to a.sta.gering 139 million by the... 详细信息

关键词： a.zheimer predomina.t estima.es

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Cha.a.teriza.ion of conception dra.ing in a.chitecture to fa.e technologica. media.ions

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Frontiers of a.chitectura. Resea.ch 2024年第3期13卷 425-438页

作者： Hugo C.gomez-Tone Ja.ier F.Ra.oso Gra. Depa.ta.ento de Idea.ión Gráfica.a.quitectónica Universidad Politécnica de MadridMadrid 28040Spain Depa.ta.ento de a.quitectura Universidad Nacional de San Agustín de ArequipaArequipa 04001Peru

The conception dra.ing in a.chitecture is tha. a.lows to initia.e the a.chitectura. thinking,visua.izing,a.d discovering the first *** dra.ing ha. tra.itiona.ly been given a. a. a.t of linking a.d colla.ora.ion between thought,sight,a.d the movement of the ha.ds with a.*** a.d recognizing its cha.a.teristics will ma.e it possible to dea. with a.y media.ion of informa.ion *** esta.lish such cha.a.teristics,three ca.e studies were ca.ried *** a.a.ysis wa. ma.e of the conception dra.ings a.d interviews by the Pritzker Prize la.rea.es:a.do,Ha.id a.d *** condition a.d four cha.a.teristics ha.e been determined:dra.ing is a.phenomenologica. a.tion tha. produces ha.tic dra.ings;it is a. undecided process tha. origina.es unformed dra.ings;it is a.fa.t a.tion tha. results in sma.l a.d multiplied dra.ings;it is a.perceptua. a.t tha. genera.es redra.n a.d rema.ked dra.ings;a.d fina.ly,it is a. a.tion tha. seeks to remember to resume the crea.ive process a. a.other moment,which produces rudimenta.y conventiona. *** these before a.y technologica. media.ion will be a. importa.t peda.ogica. contribution tha. will a.low future a.chitects not to a.ter the cognitive processes tha. genera.e the first idea. in the initia. moments of the a.chitectura. project.

关键词： Conception dra.ing a.chitectura. thinking Gra.hic idea.ion Concept Crea.ivity

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New pha.ma.ologica. tools:the use of diterpenes to promote a.ult hippoca.pa. neurogenesis

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Neura. Regenera.ion Resea.ch 2024年第8期19卷 1629-1630页

作者： Rica.do gomez-Oliva.Pedro Nunez-a.a.es Ca.men Ca.tro Depa.tment of Biomedicine Biotechnology and Public HealthDivision of PhysiologyUniversity of CadizCadizSpain Biomedica. Resea.ch a.d Innova.ion Institute of Ca.iz(INiBICa. CadizSpain Depa.tment of Physiology University of SevilleSevilleSpain

Tissue regenera.ion ma.nta.ns homeosta.is a.d preserves the functiona. fea.ures of ea.h ***,not a.l tissues show a.strong repa.ring *** is the ca.e of the centra. nervous *** is now well esta.lished tha. the genera.ion of new functiona. neurons from stem cells in the a.ult bra.n occurs in specific regions of the bra.n of different species such a. rodents,birds,prima.es,a.d huma.s(Eriksson et a..,1998).

关键词： ca.a.ity ma.nta.n preserve

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The globa. sta.ility a.d optima. control of the COVID-19 epidemic model

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Interna.iona. Journa. of Bioma.hema.ics 2024年第1期17卷 1-28页

作者： Fengsheng Chien Ha.sa. Sa.eri Nik Moha.ma. Shira.ia.t J.F.gomez-a.uila. School of Fina.ce a.d a.counting Fuzhou University of Interna.iona. Studies a.d Tra.e Fuzhou 352020 P.R.China Fa.ulty of Business City university of Macao Macao 999078P.R.China Depa.tment of Ma.hema.ics a.d Sta.istics University of Neysha.ur NeyshaburIran CONa.yT-Tecnologico Na.iona. de Mécico/CENIDET Interior Interna.o Pa.mira.S/N Col.Palmira C.P.62490CuernavacaMorelosMérico

This pa.er considers sta.ility a.a.ysis of a.Susceptible-Exposed-Infected-Recovered-Virus(SEIRV)model with nonlinea. incidence ra.es a.d indica.es the severity a.d wea.ness of control fa.tors for disea.e *** Lya.unov function using Volterra.Lya.unov ma.rices ma.es it possible to study the globa. sta.ility of the endemic equilibrium *** optima. control stra.egy is proposed to prevent the sprea. of corona.irus,in a.dition to governmenta. *** objective is to minimize together with the qua.tity of infected a.d exposed individua.s while minimizing the tota. costs of trea.ment.a.numerica. study of the model is a.so ca.ried out to investiga.e the a.a.ytica. results.

关键词： Globa. sta.ility SEIRV epidemic model dyna.ica. systems Volterra.Lya.unov sta.ility optima. control

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