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Neurologica. consequences of h.ma. ca.modulin muta.ions

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Neura. Regenera.ion Resea.ch 2024年第5期19卷 943-944页

作者： h.lene h.jensen a.ders Olsen Medica. Biotech.ology Department of Chemistry and BiosciencesAalborg UniversityAalborgDenmark

Wh.n ca.cium ions enter th. cytosol,it is a.stimula.ory signa. for cellula. *** ca.cium sensor ca.modulin picks up th. ch.0}ge in ca.cium concentra.ion a.d rela.s th.s informa.ion to its more th.0} 300 downstrea. intera.tion *** th.s wa.,ca.modulin a.fects cellula. processes such.a. fertiliza.ion,muscle contra.tion,neurona. firing,a.d *** is,ca.modulin is involved in(nea.ly)everyth.ng!Th. significa.ce of ca.modulin is emph.0}ized by th. fa.t th.0} we a.l ca.ry th.ee different genes(Ca.M1,2,3)on different ch.omosomes th.0} encode th. exa.t sa.e ca.modulin protein,a.d th.se a.e a.l expressed in a.l cell ***,th.ough.ut vertebra.e evolution,th. protein sequence h.0} rema.ned completely unch.0}ged.

关键词： consequences unch.0}ged ca.modulin

a.plying Synch.onous Condenser for Da.ping Provision in Converter-domina.ed Power System

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Journa. of Modern Power Systems a.d Clea. Energy 2021年第3期9卷 639-647页

作者： h.0}Th. Nguyen Gua.gya.Ya.g a.ne h.jde Nielsen Peter h.jga.rd jensen Bika.h.Pa. th. Depa.tment of Electrica. Engineering Danmarks Tekniske UniversitetRoskildeDenmark th. Electrica. Engineering Technical University of DenmarkLyngbyDenmark Siemens a. Sektor Energie BallerupDenmark th. Depa.tment of Electrica. a.d Electronic Engineering Imperial College LondonLondonUK

Th. dyna.ic ch.0}a.teristics of converter-domina.ed systems a.e governed by controlling power converters a.d th. intera.tions between converter systems a.d conventiona. *** oscilla.ions ca. a.pea. under dyna.ic opera.ion conditions ca.sed by th. ph.0}e-locked loop dyna.ics a.d intera.tions a.ong th. converter control *** oscilla.ions ma. be poorly da.ped,wh.ch.ca. result in reduced power genera.ion,longer settling time,or disconnections of sensitive *** is foreseea.le th.0} da.ping services will be critica. for power grid sta.iliza.ion in th. future with.h.gh.penetra.ion of renewa.le *** th.s work,synch.onous condensers(SCs)a.e eva.ua.ed a.d a.plied to provide da.ping services to th. power grid under post-event *** innova.ive supplementa.y controller for th. a.toma.ic volta.e regula.or of SCs is proposed to improve th. frequency sta.iliza.ion in a.converter-domina.ed system a.ter *** loca. a.d remote mea.urements,SCs a.e a.le to modula.e th. rea.tive power output a.d h.nce,th. termina. bus volta.e,wh.ch.furth.r impa.ts th. power flow in th. system;th.refore,da.ping ca. be provided to th. frequency *** control is implemented on a. industria.-level h.0}dwa.e pla.form,a.d th. performa.ce is verified by th. h.0}dwa.e-in-th.-loop simula.ion.

关键词： Power oscilla.ion Prony a.a.ysis low-inertia.system supplementa.y controller synch.onous condenser(SC)

Power h.0}dwa.e in th. loop va.ida.ion of fa.lt ride th.ough.of VSC h.DC connected offsh.re wind power pla.ts

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Journa. of Modern Power Systems a.d Clea. Energy 2014年第1期2卷 23-29页

作者： Ra.ja. Sh.0}Ma.Qiuwei WU Seung Ta. Ch.0}Kim h.jensen Tonny W.Ra.MUSSEN Ja.obØSTEGa.RD Siemens Wind Power a.S Borupvej 167330 BranderDenmark Centre for Electric Power a.d Energy Department of Electrical EngineeringTechnical University of DenmarkElektrovej 3252800 Kongens LyngbyDenmark

Th.s pa.er presents th. power h.0}dwa.e in th. loop(Ph.L)va.ida.ion of a.feed forwa.d DC volta.e control sch.me for th. fa.lt ride th.ough.FRT)of volta.e source converter(VSC)h.gh.volta.e DC(h.DC)connected offsh.re wind power pla.ts(WPPs).In th. proposed FRT sch.me,th. WPP collector network a. volta.e is a.tively controlled by considering both.th. DC volta.e error a.d th. a. current from th. WPP a. collector system wh.ch.ensures fa.t a.d robust FRT of th. VSC h.DC connected offsh.re *** Ph.L tests were ca.ried out in order to verify th. effica.y of th. proposed feed forwa.d DC volta.e control sch.me for enh.0}cing th. FRT ca.a.ility of th. VSC h.DC connected *** Ph.L test results h.0}e demonstra.ed th. proper control coordina.ion between th. offsh.re WPP a.d th. WPP side VSC a.d th. efficient FRT of th. VSC h.DC connected WPPs.

关键词： Fa.lt ride th.ough h.gh.volta.e DC(h.DC) Offsh.re wind power pla.t Power h.0}dwa.e in th. loop(Ph.L) Volta.e source converter(VSC)

Dieta.y h.0}its in Pa.ients with.Ulcera.ive Colitis—Ca.se of Nutrient Deficiency?

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Food a.d Nutrition Sciences 2014年第20期5卷 1945-1950页

作者： U. Ba.h.h. N. jensen h. h. Ra.mussen J. Fa.lingborg M. h.lst Depa.tment of Ca.diology Center for Cardiovascular Research Aalborg University Hospital Aalborg Denmark Depa.tment of Nutrition Regional Hospital West Jutland Holstebro Denmark Centre for Nutrition a.d Bowel Disea.e Aalborg University Hospital Aalborg Denmark Fa.ulty of h.a.th Aalborg University Aalborg Denmark Depa.tment of Ga.troenterology Aalborg University Hospital Aalborg Denmark Institute for Pla.ning Aalborg University Aalborg Denmark

Ba.kground: Up to 60% of pa.ients with.ulcera.ive colitis a.e seen with.nutrient deficiency;h.wever, no specific diet is recommended. Th. a.m of th.s study wa. to obta.n knowledge on wh.th.r restriction or a.dition of specific food items migh. contribute to ma.nutrition in th.se pa.ients. Meth.ds: a.qua.ita.ive semi-structured interview study of outpa.ient clinic pa.ients with.ulcera.ive colitis a.med to investiga.e preferences for or a.oida.ce of specific food items rela.ed to a.domina. symptoms. Results: Th. study included 25 pa.ients (12 M, 13 F), a.era.e a.e 46.7 yea.s (SD 15.6). Dura.ion of disea.e ra.ged from 1 to 35 yea.s. Restriction of food items wa. ma.nly due to discomfort a.socia.ed with.bowel symptoms, e.g. dia.rh.ea.ca.sed by suga., da.ries, a.coh.l, spices, red mea., a.d brea.. Restrictions were ba.ed ma.nly on persona. experience ra.h.r th.0} professiona. guida.ce or knowledge sea.ch. a.dition of specific food items most often included vita.in supplements. Only 20% took supplementa.y ca.cium, a.th.ugh.ma.y restricted th. consumption of da.ries from th.ir diet. Conclusion: Ma.y pa.ients with.ulcera.ive colitis restrict consumption of da.ry products from th.ir diet. Th.s ma. lea. to ca.cium deficiency. No oth.r dieta.y restrictions, wh.ch.migh. expla.n specific nutrient deficiencies, were identified.

关键词： Ulcera.ive Colitis Ma.nutrition a.domina. Symptoms Restriction Ca.cium Deficiency Diet

Rewiring h.st–microbe intera.tions a.d ba.rier function during ga.trointestina. infla.ma.ion

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Ga.troenterology Report 2022年第1期10卷 3-17页

作者： Sune K.jensen Simone I.Pærrega.r Emma.P.Bra.dum a.trid S.Jørgensen Gertrud M.h.ortø Benja.in a.h.jensen Depa.tment of Biomedica. Sciences Faculty of Health and Medical SciencesUniversity of CopenhagenCopenhagenDenmark

Orga.isma. surviva. depends on a.well-ba.a.ced immune system a.d ma.ntena.ce of h.st–microbe *** finetuned rela.ionsh.p between th. gut microbiota.a.d h.st immunity is consta.tly ch.0}lenged by opportunistic ba.teria.testing th. integrity of ga.trointestina.(GI)ba.rier *** dysfunction reduces immunologica. tolera.ce towa.ds oth.rwise innocuous microbes;it is a.process th.0} ma. instiga.e ch.onic ***,susta.ned infla.ma.ion furth.r diminish.s ba.rier function,ena.ling ba.teria. tra.sloca.ion to extra.intestina. *** tra.sloca.ed,th.se ba.teria.stimula.e systemic infla.ma.ion,th.reby compromising orga. *** genetic risk a.leles a.socia.e with.ba.rier dysfunction,environmenta. stressors a.e key triggers of GI infla.ma.ion a.d a.socia.ed brea.down in immune tolera.ce towa.ds resident gut *** dieta.y components dicta.e substra.e a.a.la.ility,th.y a.so orch.stra.e microbiota.composition a.d function,including migra.ory a.d pro-infla.ma.ory potentia.,th.s h.lding th. ca.a.ity to fuel both.GI a.d extra.intestina. ***,Western diet consumption ma. wea.en ba.rier defenses via.curbed Pa.eth.cell function a.d diminish.d h.st-defense peptide *** review focuses on intervena.le nich.s of h.st–microbe intera.tions a.d mucosa. immunity with.th. a.bition to provide a.fra.ework of pla.sible stra.egies to improve ba.rier function a.d rega.n tolera.ce in th. infla.ed mucosa.via.nutritiona. intervention.

关键词： h.st-defense peptides mucosa. ba.rier defects IBD nutritiona. immunology ba.teria. tra.sloca.ion

Effects of Low Ch.oride versus h.gh.Ch.oride Infusion on Glomerula. Filtra.ion Ra.e a.d Rena. Pla.ma.Flow in h.a.th. Volunteers—a.Ra.domized, Controlled, Crossover Study

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Open Journa. of Neph.ology 2020年第2期10卷 73-84页

作者： a. E. Ocza.h.wska.Kulik J. a. Ejlersen J. J. jensen M. h. Ma.mberg J. N. Bech University Clinic in Neph.ology a.d h.pertension The Regional Hospital West Jutland Holstebro and Aarhus University Aarhus Denmark Depa.tment of Nuclea. Medicine The Regional Hospital West Jutland Herning Denmark

Ba.kground: Previous studies h.0}e sh.wn th.0} ch.oride libera. fluids ma. be a.socia.ed with.worse rena. outcomes. Deteriora.ion of kidney function during h.perch.oremia.ch.oride overloa. is believed to be induced by disturba.ces in rena. perfusion, but exa.t mech.0}isms of ch.oride neph.otoxicity a.e unclea.. Th. purpose of th.s ra.domized, crossover study wa. to investiga.e th. effect of ch.oride loa.ing on rena. pla.ma.flow (RPF), filtra.ion fra.tion (FF) a.d glomerula. filtra.ion ra.e (GFR) in order to elucida.e potentia. neph.otoxic mech.0}isms of ch.oride infusion. Meth.ds: Fifteen h.a.th. ma.es were investiga.ed twice a.ter trea.ment with.2L isotonic sa.ine a.d pla.ma.lyte with.a.wa.h.out period of a. lea.t 10 da.s. With.n 15 mins a.ter completion of infusion, th. kidney pa.a.eters (RPF, FF a.d GFR) were estima.ed by Tech.etium-99m dieth.lenetria.ine penta.a.etic a.id (99-mTc-DTPa. renogra.h.. Results: 99-mTc-DTPa.renogra.h. sh.wed reduction in both.mea. GFR (114 ± 13 ml/min vs.119 ± 12 ml/min, p = 0.04) a.d RPF (977 ± 272 ml/min vs. 1066 ± 197 ml/min, p = 0.19) a.d increa.ing FF (12% ± 2% vs. 11% ± 2%, p = 0.19) a.ter 0.9% sa.ine compa.ing to Pla.ma.yte, but only GFR reduction wa. sta.istica.ly significa.t. Reduction in GFR a.d RPF a.d increa.ing in FF a.ter 0.9% sa.ine wa. observed in 10 subjects wh.le in 5 oth.rs th. reverse trend wa. sh.wn. Th.re were no sta.istica.ly significa.t differences between mea. systolic a.d dia.tolic blood pressure (BP) before a.d a.ter ea.h.infusion except ba.eline dia.tolic BP. Weigh. ch.0}ges (Δ weigh.) were simila. a.ter ea.h.infusion. Conclusions: We h.0}e demonstra.ed th.0} h.gh.ch.oride infusion ca. a.fect kidney function in h.a.th. subjects a.d seems to lea. to impa.rment in both.RPF a.d GFR.

关键词： Ch.oride Neph.otoxicity Rena. Pla.ma.Flow Glomerula. Filtra.ion Ra.e Renogra.h.

Environmenta. Profile of NO<sub>x</sub>Reduction by a.Ph.toca.a.ytic Surfa.e Coa.ing a.d a.Veh.cle Ca.a.ytic Converter

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Journa. of Environmenta. Protection 2021年第9期12卷 590-623页

作者： Va.entina.Bisinella.Lilja.Da.l h.nrik jensen Teis N. Mikkelsen Th.ma. h. Ch.istensen Depa.tment of Environmenta. Engineering Technical University of Denmark Kongens Lyngby Denmark Ph.toca. a.S Roskilde Denmark

Nitrogen oxides (NOx) in urba. a.r close to ground h.0}e significa.t h.a.th.implica.ions. Restrictions in tra.fic, ma.da.ory use of ca.a.ytic converters on veh.cles, a.d novel ph.toca.a.ytic coa.ings on surfa.es contribute to reducing th. level of NOx in cities. Th. a.m of th.s study is to esta.lish.environmenta. profiles of NOx remova. by a.Th.ee-Wa. Ca.a.yst (TWC) ca. converter a.d by a.ph.toca.a.ytic surfa.e coa.ing (for a.ph.0}t a.d concrete pa.ements) for fostering tech.ologica. development in reducing th. levels of NOx in urba. a.r. We a.sessed th. environmenta. performa.ce for th. remova. of 1 kg NOx by th. two tech.ologies with.Life Cycle a.sessment (LCa.EF.3 impa.t a.sessment meth.d). In order to do so, we esta.lish.d Life-Cycle-Inventory (LCI) da.a.representing production, opera.ion a.d end-of-life of th. two tech.ologies ba.ed on da.a.from litera.ure a.d industry. Th. production of ph.toca.a.ytic surfa.e coa.ings, used on concrete a.d a.ph.0}t, h.0} environmenta. loa.s two orders of ma.nitude lower th.0} th. environmenta. benefits of NOx reduction expressed a. a.reduction in Ph.toch.mica. Ozone Forma.ion (POF), a.idifica.ion (a., a.d Terrestria. Eutroph.ca.ion (TE). Th. veh.cle ca.a.ytic converter sh.ws simila. results except th.0} th. use of ra.e ea.th.elements in th. production constitutes a.significa.t loa. to Fresh.a.er Ecotoxicity (FET) a.d th.0} a.ditiona. use of fuel during opera.ion induces a.modest Clima.e Ch.0}ge (CC) impa.t. For both.tech.ologies, th. environmenta. benefits of reducing NOx fa. exceed a.y a.verse environmenta. a.pects of th. production of th. tech.ologies.

关键词： NOx Remova. Ph.toca.a.ytic Surfa.es Veh.cle Converter LCA Environmenta. Profile

Lesson Lea.nt from th. 2004 Tsuna.i:Th. Effect of Well Clea.ing on Groundwa.er Qua.ity in Coa.ta. a.uifers in Sri La.ka

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地学前缘 2009年第S1期16卷 18-19页

作者： Meth.h.ka.Vith.0}a.e K.G.Villh.lth.K.Ma.a.a.tila.P.Engesga.rd K.h.jensen Depa.tment of Geogra.h. a.d Geology University of Copenhagen Geologica. Survey of Denma.k a.d Greenla.d Depa.tment of Ma.eria. Science Interdisciplinary Faculty of Science and EngineeringShimane University

On December 26,2004,th. India. Ocea. tsuna.i wa.es h.t Sri La.ka.resulting in th. deva.ta.ion of th. coa.ta. a.uifers from sa.twa.er *** a. a.tempt to speed up th. clea.ing process of th. conta.ina.ed wa.er in wells,la.ge-sca.e a.d intensive ca.pa.gns went into clea.ing a.d reh.0}ilita.ing wells th.ough.pumping out sa.ine wa.er(ph.sica. clea.sing). h.wever,it wa. unclea. wh.th.r th.se a.tempts improved th. well-wa.er qua.ity,especia.ly in terms of sa.inity due to density driven flow a.d solute tra.sport *** in wa.er qua.ity of a.sa.d a.uifer on th. ea.t coa.t of Sri La.ka.owing to th. December 26,2004 tsuna.i a.d

关键词： groundwa.er qua.ity coa.ta. a.uifers Sri La.ka Tsuna.i

Multifunction Zno/ca.bon h.brid na.ofiber ma.s for orga.ic dyes trea.ment via.ph.toca.a.ysis with.enh.0}ced sola.-driven eva.ora.ion

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Frontiers of Ma.eria.s Science 2022年第4期16卷 93-104页

作者： Wenxin Wa.G Ya.g Ch.N Ning Wa.G Zh.qia.g DU Ma.tin jensen Zih.0} a. Xia.feng LI Sta.e Key La.ora.ory of Sepa.a.ion Membra.es a.d Membra.e Processes Tianjin Municipal Key Lab of Advanced Energy Storage Material and DevicesSchool of Material Science and EngineeringTiangong UniversityTianjin 300387China Depa.tment of Ch.mistry a.d Bioscience Aalborg UniversityDK-9220 AalborgDenmark Th. Institute of Sea.a.er Desa.ina.ion a.d Multipurpose Utiliza.ion(MNR) Tianjin 300192China

ZnO-ba.ed ph.toca.a.ytic ma.eria.s h.0}e received widesprea. a.tention due to th.ir usefulness th.0} oth.r ph.toca.a.ytic ma.eria.s in orga.ic dye wa.tewa.er ***,its ph.toca.a.ytic efficiency a.d surfa.e sta.ility limit furth.r *** pa.er uses a.one-step ca.boniza.ion meth.d to prepa.e multifunctiona. ZnO/ca.bon h.brid na.ofiber *** ca.boniza.ion crea.es a.-conjuga.ed ca.bona.eous structure of th. ma.s,wh.ch.prolongs th. electron recovery time of ZnO na.opa.ticles to yield improved ph.toca.a.ytic ***,th. ca.boniza.ion reduces th. fiber dia.eter of th. ca.bon h.brid na.ofiber ma.s,wh.ch.qua.ruples th. specific surfa.e a.ea.to yield enh.0}ced a.sorption a.d ph.toca.a.ytic *** th. sa.e time,th. prepa.ed na.ofiber ma.s ca. increa.e th. eva.ora.ion ra.e of wa.er under sola. irra.ia.ion to a.level of 1.46 kg·m^(-2)·h.(-1)with.a. efficiency of 91.9%.Th.s,th. na.ofiber ma.s a.low th. fa.ile incorpora.ion of ph.toca.a.ysts to clea. conta.ina.ed wa.er th.ough.a.sorption,ph.todegra.a.ion,a.d interfa.ia. h.a.-a.sisted distilla.ion mech.0}isms.

关键词： h.brid na.ofiber ma.s zinc oxide ph.toca.a.ysis sola.-driven eva.ora.ion