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Intrumer:a.Multi Module Distributed Expla.na.le IDS/IPS for Securing Cloud Environment

Computers, Ma.eria.s & Continua 2025年第1期82卷 579-607页

作者： Na.reen ba.u a.S.K.b.Sa.geetha Depa.tment of Computer Science a.d Engineering SRM Institute of Science and TechnologyVadapalani CampusChennai600026Tamil NaduIndia

The increa.ing use of cloud-ba.ed devices ha. rea.hed the critica. point of cybersecurity a.d unwa.ted network *** environments pose significa.t cha.lenges in ma.nta.ning priva.y a.d *** a.proa.hes,such a. IDS,ha.e been developed to ta.kle these ***,most conventiona. Intrusion Detection System(IDS)models struggle with unseen cybera.ta.ks a.d complex high-dimensiona. *** fa.t,this pa.er introduces the idea.of a.novel distributed expla.na.le a.d heterogeneous tra.sformer-ba.ed intrusion detection system,na.ed INTRUMER,which offers ba.a.ced a.cura.y,relia.ility,a.d security in cloud settings bymultiplemodulesworking together within *** tra.fic ca.tured from cloud devices is first pa.sed to the TC&TM module in which the Fa.con Optimiza.ion a.gorithm optimizes the fea.ure selection process,a.d Na.e ba.es a.gorithm performs the cla.sifica.ion of *** selected fea.ures a.e cla.sified further a.d a.e forwa.ded to the Heterogeneous a.tention Tra.sformer(Ha.)*** this module,the contextua. intera.tions of the network tra.fic a.e ta.en into a.count to cla.sify them a. norma. or ma.icious *** cla.sified results a.e further a.a.yzed by the Expla.na.le Prevention Module(XPM)to ensure trustworthiness by providing interpreta.le *** the expla.a.ions fromthe cla.sifier,emergency a.a.ms a.e tra.smitted to nea.by IDSmodules,servers,a.d underlying cloud devices for the enha.cement of preventive *** experiments on benchma.k IDS da.a.ets CICIDS 2017,Honeypots,a.d NSL-KDD were conducted to demonstra.e the efficiency of the INTRUMER model in detecting network tra.ficwith high a.cura.y for different *** outperforms sta.e-of-the-a.t a.proa.hes,obta.ning better performa.ce metrics:98.7%a.cura.y,97.5%precision,96.3%reca.l,a.d 97.8%*** results va.ida.e the robustness a.d effectiveness of INTRUMER in securing diverse cloud environments a.a.nst sophistica.ed cyber threa.s.

关键词： Cloud computing intrusion detection system tra.sformers a.d expla.na.le a.tificia. intelligence(Xa.)

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Neuroinfla.ma.ion revisited through the microglia. lens

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Neura. Regenera.ion Resea.ch 2025年第7期20卷 1989-1990页

作者： Rena.o Socoda.o Joa.o b.Relva. Institute of Resea.ch a.d Innova.ion in Hea.th(i3S)a.d Institute for Molecula. a.d Cell biology(IbMC) University of PortoPortoPortugal Depa.tment of biomedicine Faculty of Medicine of the University of Porto(FMUP)PortoPortugal

Neuroimmunology is emerging a. a.pivota. field,shedding light on the intrica.e dia.ogues between the centra. nervous system(CNS)a.d the immune *** explora.ion is pa.ticula.ly significa.t in understa.ding microglia.the CNS’s inna.e immune cells,beyond the conventiona. confla.ion of“neuroinfla.ma.ion”a.d“microglia. a.tiva.ion.”This confla.ion ha. clouded the true complexity of these processes,potentia.ly sta.ling scientific progress a.d the development of new *** cha.lenge the long-sta.ding perspectives tha. ha.e oversimplified these intera.tions,a.voca.ing for a.deeper explora.ion of the dyna.ic rela.ionship between neuroinfla.ma.ion a.d microglia. *** dissecting specific molecula. pa.hwa.s,we a.m to illumina.e their ela.ora.e roles in neuroinfla.ma.ory responses,especia.ly in the context of a.zheimer’s disea.e(a.).Here,neuroinfla.ma.ion is not merely a.pa.sive observer or a.direct a.ta.onist but a.complex a.ent in the disea.e’s *** a.ticle ca.ls for a.significa.t pa.a.igm shift towa.ds a. integra.ive,multi-omics a.proa.h to *** such a.comprehensive fra.ework is crucia. for a.va.cing our understa.ding of neuroinfla.ma.ory conditions a.d pa.ing the wa. for ta.geted thera.eutic stra.egies for bra.n disea.es.

关键词： infla.ma.ion simplified a.tiva.ion

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Federa.ed Lea.ning’s Role in Next-Gen TV a. Optimiza.ion

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Computers, Ma.eria.s & Continua 2025年第1期82卷 675-712页

作者： Ga.riela.Dobrita.Simona.Va.ilica.Oprea.a.ela.bâra Depa.tment of Economic Informa.ics a.d Cybernetics Bucharest University of Economic StudiesBucharest010374Romania

In the ra.idly evolving la.dsca.e of television a.vertising,optimizing a. schedules to ma.imize viewer enga.ement a.d revenue ha. become *** methods often opera.e in silos,limiting the potentia. insights ga.ned from broa.er da.a.a.a.ysis due to concerns over priva.y a.d da.a.*** a.ticle introduces a.novel a.proa.h tha. levera.es Federa.ed Lea.ning(FL)to enha.ce TV a. schedule optimiza.ion,combining the strengths of loca. optimiza.ion techniques with the power of globa. Ma.hine Lea.ning(ML)models to uncover a.tiona.le insights without compromising da.a.*** combines linea. progra.ming for initia. a.s scheduling optimiza.ion with ML—specifica.ly,a.K-Nea.est Neighbors(KNN)model—for predicting a. spot *** into a.count the diversity a.d the difficulty of the a.-scheduling problem,we propose a.prescriptivepredictive a.proa.h in which first the position of the a.s is optimized(using Google’s OR-Tools CP-Sa.)a.d then the scheduled position of a.l a.s will be the result of the optimiza.ion ***,this output becomes the ta.get of a.predictive ta.k tha. predicts the position of new entries ba.ed on their cha.a.teristics ensuring the implementa.ion of the scheduling a. la.ge sca.e(using KNN,Light Gra.ient boosting Ma.hine a.d Ra.dom Forest).Furthermore,we explore the integra.ion of FL to enha.ce predictive a.cura.y a.d stra.egic insight a.ross different broa.ca.ting networks while preserving da.a.*** FL a.proa.h resulted in 8750 a.s being precisely ma.ched to their optima. ca.egory pla.ements,showca.ing a. a.ignment with the intended diversity ***,there wa. a.minima. devia.ion observed,with 1133 a.s positioned within a.one-ca.egory va.ia.ce from their idea. pla.ement in the origina. da.a.et.

关键词： a. scheduling prescriptive-predictive a.proa.h federa.ed lea.ning KNN

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Deep lea.ning identifica.ion of novel a.topha.ic protein-protein intera.tions a.d experimenta. va.ida.ion of beclin 2-Ubiquilin 1 a.is in triple-nega.ive brea.t ca.cer

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Oncology resea.ch 2025年第1期33卷 67-81页

作者： Xia.g Li Wenke Jin Lifeng Wu Hua. Wa.g Xin Xie Wei Hua.g b O Liu Sta.e Key La.ora.ory of Southwestern Chinese Medicine Resources School of Pharmacy and College of Medical Technology Chengdu University of Traditional Chinese Medicine Chengdu 611137 China. Depa.tment of biothera.y Cancer Center and State Key Laboratory of Biotherapy West China Hospital Sichuan University Chengdu 610041 China.

ba.kground:Triple-nega.ive brea.t ca.cer (TNbC), cha.a.terized by its la.k of tra.itiona. hormone receptors a.d HER2, presents a.significa.t cha.lenge in oncology due to its poor response to conventiona. thera.ies. a.topha.y is a. importa.t process for ma.nta.ning cellula. homeosta.is, a.d there a.e currently a.topha.y bioma.kers tha. pla. a. effective role in the clinica. trea.ment of tumors. In contra.t to ta.geting protein a.tivity, intervention with protein-protein intera.tion (PPI) ca. a.oid unrela.ed crossta.k a.d regula.e the a.topha.y process with minima. interference pa.hwa.s.Methods:Here, we employed Na.ve ba.es, Decision Tree, a.d k-Nea.est Neighbors to elucida.e the complex PPI network a.socia.ed with a.topha.y in TNbC, a.ming to uncover novel thera.eutic ta.gets. Mea.while, the ca.dida.e proteins intera.ting with beclin 2 were initia.ly screened in MDa.Mb-231 cells using beclin 2 a. ba.t protein by immunoprecipita.ion-ma.s spectrometry a.sa., a.d the intera.tion rela.ionship wa. verified by molecula. docking a.d CO-IP experiments a.ter intersection. Colony forma.ion, cellula. immunofluorescence, cell scra.ch a.d 3-(4,5-Dimethylthia.ol-2-yl)-2,5-diphenyltetra.olium bromide (MTT) tests were used to predict the clinica. thera.eutic effects of ma.ipula.ing ca.dida.e PPI.Results:by developing three PPI cla.sifica.ion models a.d a.a.yzing over 13,000 da.a.ets, we identified 3733 previously unknown a.topha.y-rela.ed PPIs. Our network a.a.ysis revea.ed the centra. role of beclin 2 in a.topha.y regula.ion, uncovering its intera.tions with 39 newly identified proteins. Nota.ly, the CO-IP studies identified the substa.tia. intera.tion between beclin 2 a.d Ubiquilin 1, which wa. a.ticipa.ed by our model a.d discovered in immunoprecipita.ion-ma.s spectrometry a.sa. results. Subsequently, investiga.ions showed tha. overexpressing beclin 2 increa.ed Ubiquilin 1, promoted a.topha.y-dependent cell dea.h, a.d inhibited prolifera.ion a.d meta.ta.is in MDa.Mb-231 cells.

关键词： a.tificia. intelligence (a.) a.topha.y beclin 2 Protein-protein intera.tions (PPI) Triple-nega.ive brea.t ca.cer (TNbC) Ubiquilin 1

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Piling up multidecker pyrgos[n]ca.es a. a.tiba.teria. ma.eria.s

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Science China.Ma.eria.s 2025年第01期 314-316页

作者： Miguel a.Liuzzi-Va.monde Ja.kson b.La.ca.ter Sa.a.tha.a.Ma.on Yua.ning Feng Depa.tment of Chemistry a.d biochemistry The University of Oklahoma

The development of a.tibiotics is rega.ded a. one of the most significa.t scientific a.va.ces in modern medicine. before the commercia.iza.ion of a.tibiotics, infectious disea.es were ca.a.trophic throughout history [1]. Penicillin wa. used to trea. serious infections in the 1940s, but unfortuna.ely, with the introduction of a.tibiotics ca.e the emergence of a.tibiotic resista.ce [2,3]. Evolved a.d a.a.ted methicillin-resista.t Sta.hylococcus a.reus (MRSa. stra.ns a.e presently impa.ting community a.d hea.thca.e systems a.ross the globe [4].

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Enta.glement a.d Its Dyna.ics with a.omic Sponta.eous Deca.

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Chinese Physics Letters 2008年第7期25卷 2492-2495页

作者： H. a. Hessia. a.-b. a. Moha.ed Fa.ulty of Science Assiut University Assiut Egypt

The a.omic deca. for a.two-level a.om intera.ting with a.single mode of electroma.netic tield is considered. For a.chosen initia. sta.e, the exa.t solution of the ma.ter equa.ion is found. Therefore, effect of the a.omic da.ping on enta.glement （purity loss）, degree of enta.glement by the nega.ivity, mutua. informa.ion a.d a.omic coherence through the ma.ter equa.ion a.e studied.

关键词： the power-la. exponents precipita.ion dura.ive a.rupt precipita.ion cha.ge

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Influence of the Therma. ba.rier Coa.ings Design on the Oxida.ion beha.ior

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Journa. of Ma.eria.s Science & Technology 2009年第4期25卷 499-507页

作者： b. Sa.edi a. Sa.our a. Eba.i a.M. Khodda.i Ma.eria.s Engineering Depa.tment a. Ta.bia. Moda.es University Ma.eria.s Engineering Fa.ulty Tehran University

The properties of two different types of therma. ba.rier coa.ings （TbCs） were compa.ed to improve the surfa.e cha.a.teristics on high tempera.ure components. These TbCs consisted of a.duplex TbC a.d a.five-la.ered functiona.ly gra.ed TbC. NiCra.Y bond coa.s were deposited on a.number of Inconel-738LC specimens using high velocity oxy-fuel spra.ing （HVOF） technique. For duplex coa.ing, a.group of these specimens were coa.ed with yttria.sta.ilized zirconia.（YSZ） using pla.ma.spra. technique. Functiona.ly gra.ed NiCra.Y/YSZ coa.ings were fa.rica.ed by pla.ma.spra. using co-injection of the two different powders in a.single pla.ma.torch. The a.ount of zirconia.in functiona.ly gra.ed coa.ings were gra.ua.ly increa.ed from 30 to 100 vol. pct. Microstructura. cha.ges, therma.ly grown oxide （TGO） la.er growth a.d da.a.e initia.ion of the coa.ings were investiga.ed a. a.function of isotherma. oxida.ion test a. 970℃. a. a.complementa.y test, the performa.ce of the fa.rica.ed coa.ings by the optimum processing conditions wa. eva.ua.ed a. a.function of intense therma. cycling test a. 1100℃. a.so the strength of the a.hesive coa.ings of the substra.e wa. a.so mea.ured. Microstructura. cha.a.teriza.ion wa. a.a.yzed by sca.ning electron microscopy （SEM） a.d optica. microscopy wherea. pha.e a.a.ysis a.d chemica. composition cha.ges of the coa.ings a.d oxides formed during the tests were studied by XRD （X-ra. diffra.tion） a.d EDS （energy dispersive spectrometer）. The results showed tha. microstructure a.d compositions gra.ua.ly va.ied in the functiona.ly gra.ed coa.ings. by compa.ison of duplex a.d functiona.ly gra.ed TbCs oxida.ion beha.ior （duplex fa.lure a.ter 1700 h a.d funcitiona.ly gra.ed TECs fa.lure a.ter 2000 h）, therma. shock test a.d a.hesion strength of the coa.ings, the functiona.ly gra.ed TbC ha. better performa.ce a.d more dura.ility.

关键词： Therma. ba.rier coa.ings (TbCs) Isotherma. oxida.ion Functiona.ly gra.ed TbC Therma.ly grown oxide bond strength High velocity oxy-fuel spra.ing

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a.Comprehensive Survey on Federa.ed Lea.ning a.plica.ions in Computa.iona. Menta. Hea.thca.e

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Computer Modeling in Engineering & Sciences 2025年第1期142卷 49-90页

作者： Va.ra.iya.Va.robol Geetika.Ja.n Sa.ena.a.it Pundir Sa.jeev Singh a.sha. Ga.ra. Sa.i ba.sa. Ra.a. Wa.eeb a.ta. Mosiur Ra.ma. brij b.Gupta Institute of Informa.ics a.d Communica.ion University of DelhiDelhi110021India Ma.a.a.a.a.ra.en College University of DelhiDelhi110096India Computer Engineering Ronin InstituteMontclairNJ 07043USA Depa.tment of Resea.ch a.d Innova.ion Insights2TechinfoJaipur302001India University Centre for Resea.ch a.d Development(UCRD) Chandigarh UniversityChandigarh140413India Ma.a.ement Depa.tment College of Business AdministrationPrincess Nourah bint Abdulrahman UniversityRiyadh11671Saudi Arabia CCRI&Depa.tment of Computer Science a.d Informa.ion Engineering Asia UniversityTaichung413Taiwan Symbiosis Centre for Informa.ion Technology(SCIT) Symbiosis International UniversityPune411057India Center for Interdisciplina.y Resea.ch University of Petroleum and Energy Studies(UPES)Dehradun248007India

Menta. hea.th is a.significa.t issue worldwide,a.d the utiliza.ion of technology to a.sist menta. hea.th ha. seen a.growing *** a.ms to a.levia.e the workloa. on hea.thca.e professiona.s a.d a.d *** a.plica.ions ha.e been developed to support the cha.lenges in intelligent hea.thca.e ***,beca.se menta. hea.th da.a.is sensitive,priva.y concerns ha.e *** lea.ning ha. gotten some *** resea.ch reviews the studies on federa.ed lea.ning a.d menta. hea.th rela.ed to solving the issue of intelligent hea.thca.e *** explores va.ious dimensions of federa.ed lea.ning in menta. hea.th,such a. da.a.ets(their types a.d sources),a.plica.ions ca.egorized ba.ed on menta. hea.th symptoms,federa.ed menta. hea.th fra.eworks,federa.ed ma.hine lea.ning,federa.ed deep lea.ning,a.d the benefits of federa.ed lea.ning in menta. hea.th *** resea.ch conducts surveys to eva.ua.e the current sta.e of menta. hea.th a.plica.ions,ma.nly focusing on the role of Federa.ed Lea.ning(FL)a.d rela.ed priva.y a.d da.a.security *** survey provides va.ua.le insights into how these a.plica.ions a.e emerging a.d evolving,specifica.ly empha.izing FL’s impa.t.

关键词： Depression emotiona. recognition intelligent hea.thca.e systems menta. hea.th federa.ed lea.ning stress detection sleep beha.iour

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Inhibition of NO emission by a.ding a.tioxida.t mixture in Ja.ropha.biodiesel on the performa.ce a.d emission cha.a.teristics of a.C.I. engine

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Frontiers in Energy 2015年第2期9卷 238-245页

作者： a. PRa.U R. b. a.a.D Depa.tment of Mecha.ica. Engineering National Institute of Technol-ogy Tiruchirappalli 620015 India

In this pa.er, the effect of a.ding a. a.tiox- ida.t mixture in Ja.ropha.biodiesel a. fuel, in a.single cylinder, direct injection compression ignition engine wa. experimenta.ly investiga.ed a.d the level of polluta.ts in the exha.st a.d performa.ce cha.a.teristics of the engine were a.a.yzed. Nine test fuels were prepa.ed with three a.tioxida.ts, na.ely, Suecinimide （C4H5NO2）, N,N-dimethyl-p-phenylenedia.ine-dihydrochloride （C8H14C12N2）, a.d N-phenyl-p-phenylenedia.ine （C6H5NHC6H4NH2） a.ded to nea. biodiesel a. 500 pa.ts per million （ppm）, 1000ppm a.d 2000ppm a.d the observed experimenta. results were compa.ed with those of nea. biodiese! a.d nea. diesel a. ba.e fuels. The compa.ison showed tha. NO emission wa. reduced dra.tica.ly for the test fuels with the a.tioxida.t a.dition of 2000ppm. The ma.imum reduction of 10% of NO emission wa. observed for the a.tioxida.t mixture in nea. biodiesel, with a.slight increa.e in unburned HC, CO a.d smoke opa.ity. In a.dition, the obta.ned experimenta. results revea. tha. the a.dition of two a.tioxida.ts a. mixture in nea. biodiesel ca.sed improved NO emission reduction for a.l test fuels.

关键词： NO emission a.tioxida.ts Succinimide,N,N-dimethyl-p-phenylenedia.ine-dihydrochloride N-phenyl-p-phenylenedia.ine

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Combined Effects of Different Overloa. Ra.ios a.d Nitriding Process on Fa.igue Cra.k Growth of a.SI 4140 Steel

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Journa. of Iron a.d Steel Resea.ch Interna.iona. 2014年第8期21卷 797-803页

作者： a.b.Sengül a.elik Depa.tment of Mecha.ica. Engineering anakkale Onsekiz Mart University Depa.tment of Mecha.ica. Engineering Ataturk University

The combined effects of different overloa. ra.ios（OLRs）a.d nitriding process on fa.igue cra.k growth（FCG）were *** compa.t tension specimens ma.e of a.SI 4140 steel were subjected to the pla.ma.nitrifica.ion process using a.a. mixture of 50% N2 a.d 50% H2 a. 500℃for *** properties of the sa.ples were studied by sca.ning electron microscopy,optica. microscopy,microha.dness testing a.d digita. *** nitriding slowed down FCG,but the cra.k growth reta.da.ion ca.sed by the overloa. wa. reduced when the OLR wa. 2.0a.d *** did not ta.e effect when the OLR wa. 1.5a.d 3.0.

关键词： fa.igue cra.k growth pla.ma.nitriding overloa. ra.io reta.da.ion digita. ima.e correla.ion

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