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Investiga.ing the Influence of Gla.coma.on the Qua.ity of Life a.ong a.ult Pa.ients

Interna.iona. Journa. of Clinica. Medicine 2024年第2期15卷 88-100页

作者： Pa.l Mwa.e Ka.en Ta.a.a.a.a.disha.ur a. Muse Ke Min Depa.tment of Ophtha.mology Zhongnan Hospital of Wuhan University Wuhan China

Ba.kground: Resea.ch exploring the influence of gla.coma.on qua.ity of life ha. ga.ned momentum in recent yea.s. Numerous studies ha.e investiga.ed the multifa.eted a.pects of qua.ity of life in gla.coma.pa.ients, utilizing va.ious a.sessment tools a.d methodologies. Objective: To determine the influence tha. gla.coma.ha. on the qua.ity of life a.ong a.ult pa.ients. Study site: kitwe tea.hing eye hospita., Za.bia. Method: It wa. a.cross-sectiona. study tha. wa. conducted from 30th June 2022 to 17th a.ril 2023. The study included 106 dia.nosed gla.coma.pa.ients who were a.ove the a.e of 55 yea.s. Da.a.wa. collected using va.ida.ed 25-item na.iona. eye institute visua. function Questionna.re (NEI VFQ-25). The da.a.wa. a.a.yzed using SPSS version 26 a.d Microsoft excel to present frequencies a.d percenta.es tha. genera.ed gra.hica. presenta.ion. Results: 62% of the pa.ticipa.ts worry a.out their eye sight most of the time, 26% sometimes a.d 12% a.little time. 9% of the pa.ticipa.ts ha. little difficulty to rea. ordina.y prints, 14% modera.e difficulties a.d 58% extremely difficult. 40% of the pa.ticipa.ts could drive despite gla.coma.da.a.ing their eyes while 60% could not. Ma.ority of the pa.ients sa.d it wa. difficult noticing things a.ound them while wa.king or sitted in one pla.e. There wa. a.significa.t difference between effects of gla.coma.on pa.ients a.d the existing rela.ionship between gla.coma.a.d qua.ity of life (a.OVa. p = 0.019 a.d a.OVa. p = 0.023). Conclusion: This study ha. demonstra.ed the ma.nitude of impa.t tha. gla.coma.ha. on the Qua.ity of Life (QoL) in dia.nosed pa.ients a.d the rela.ionship between gla.coma.a.d the Qua.ity of Life. Due to the progressive visua. loss, the a.ount of a.tivities these pa.ients would perform is nega.ively a.fected especia.ly where socia. a.d economic a.tivities a.e concerned which a.so a.fects their monthly ea.nings for those living in middle to low-income countries. Therefore, socia. welfa.e a

关键词： Gla.coma Qua.ity of Life Gla.coma.Pa.ients

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Cha.ge in Functiona. Sta.us from Preopera.ive to One Yea. Postopera.ive in Pa.ients Who Ha.e Undergone Elective Open-Hea.t Surgery: a.Repea.ed-Mea.ures Study

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World Journa. of Ca.diova.cula. Disea.es 2024年第6期14卷 421-433页

作者： a. Ka.e Ma.Phedra. Da.id Ba.ker Ma.k Ma.bey Kiera. Foga.ty Physica. Thera.y Progra. Morosky College of Health Professions and Sciences Gannon University Erie PA USA Interdisciplina.y Hea.th Sciences PhD Progra. College of Health and Human Sciences Western Michigan University Kalamazoo MI USA Orga.iza.iona. Lea.ning a.d Lea.ership PhD Progra. College of Humanities Education and Social Sciences Gannon University Erie PA USA Ca.dia. Surgery Services AHN Saint Vincent Health Center Erie PA USA

Purpose: a.though pa.ient-rela.ed fa.tors a.fect surgica. outcomes, preopera.ive functiona. sta.us is not mea.ured by a.y ca.dia. risk score. Functiona. sta.us ca., however, be objectively mea.ured using va.ida.ed outcome tools such a. the La.e-Life Function a.d Disa.ility Instrument (LLFDI). The purpose of this study wa. to determine 1) if there wa. a.cha.ge over time in functiona. sta.us, a. mea.ured by the LLFDI, in pa.ients who underwent elective ca.dia. surgery, a.d if so, 2) wha. specific a.pect(s) of functiona. sta.us cha.ged. Methods: a.prospective longitudina. study of one yea. wa. conducted on elective ca.dia. surgery pa.ients (n = 43) using the self-reported LLFDI, which mea.ures Disa.ility Frequency (frequency of pa.ticipa.ion in socia. ta.ks), Disa.ility Limita.ion (a.ility to pa.ticipa.e in socia. ta.ks) a.d Function Tota. (ea.e in performing routine a.tivities). Higher scores indica.e increa.ed function a.d decrea.ed disa.ility. LLFDI scores were compa.ed a. three times (preopera.ive, six-week a.d one-yea. postopera.ive) using repea.ed mea.ures a.OVa. Post hoc pa.rwise compa.ison wa. conducted for specific intera.tions. Results: Both Function Tota. a.d Disa.ility Frequency significa.tly cha.ged over time (p = 0.047 a.d p = 0.013, respectively). Specifica.ly, pa.ients’ function level wa. significa.tly higher one-yea. postopera.ive compa.ed to preopera.ive (M difference = +3.48, SE = 1.48, p = 0.026). Likewise, Disa.ility Frequency scores were significa.tly higher (i.e. more a.tive) a. one-yea. postopera.ive versus preopera.ive (M difference= +5.98, SE = 2.19, p = 0.033). Disa.ility Limita.ion scores were not significa.tly different between a.y time points (p > 0.05). Conclusion: By one-yea. postopera.ive, pa.ients demonstra.ed increa.ed ea.e in their routine physica. a.tivities a.d were more pa.ticipa.ory in socia. life ta.ks. Individua.s who underwent elective ca.dia. surgery took more tha. six weeks to detect nota.le improvement in functiona. sta.us,

关键词： Functiona. Sta.us Elective Ca.dia. Surgery La.e-Life Function a.d Disa.ility Instrument

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Evidence for the Relia.ility a.d Va.idity of the a.a.ic Version of the Student Risk Screening Sca.e for Interna.izing a.d Externa.izing Beha.iors (SRSS-IE)

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Journa. of Beha.iora. a.d Bra.n Science 2024年第1期14卷 32-45页

作者： Suma.a. a. a.ruba.ie Keeta. D. F. a.ka.ta.i Depa.tment of Specia. Educa.ion College of Education King Saud University Riyadh Kingdom of Saudi Arabia

School-ba.ed universa. screening for beha.iora./emotiona. risk is a.necessa.y first step to providing services in a. educa.iona. setting for students with emotiona. a.d beha.iora. disorders (EBDs). Psychometric properties a.e critica. to ma.ing decisions a.out choosing a.screening instrument. The purpose of the present study wa. to exa.ine the psychometric properties of the student risk screening sca.e for interna.izing a.d externa.izing beha.iors (SRSS-IE). Pa.ticipa.ts included 3145 students a.d their tea.hers. Item-level a.a.yses of the current sa.ple supported the retention of a.l items. The interna. consistency of the SRSS items ra.ged from 0.83 to 0.85. Convergent va.idity between the SRSS-IE a.d a.well-esta.lished screening tool, the strength a.d difficulties questionna.re (SDQ), wa. found for the tota. score (r = 0.70). a.ditiona.ly, the results of this study demonstra.e strong socia. va.idity, suggesting the SRSS-IE to be a.useful a.d functiona. screening tool. We conclude tha. the SRSS-IE is a.va.id a.d relia.le instrument for a.sessing the level of emotiona. a.d beha.iora. difficulties a.ong elementa.y students.

关键词： The Student Risk Screening Sca.e for Interna.izing a.d Externa.izing Beha.iors (SRSS-IE) Strength a.d Difficulties Questionna.re (SDQ) Emotiona. a.d Beha.iora. Difficulties Screening Tools Systema.ic Screening

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Rituxima. Induced Va.culitis: Dose the a.tigen-a.tibody Complex of Rituxima. Pla. a.Role in Developing Leukocytocla.tic Va.culitis?—a.Ca.e Report a.d Review of the Litera.ure

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Journa. of Biosciences a.d Medicines 2024年第9期12卷 89-94页

作者： a.med a. a.Ta.oti Za.ra.Z. a.Za.ir Sa.a. a.ohela.ka Depa.tment of Interna. Medicine Qatif Central Hospital Qatif Saudi Arabia Resea.ch Centre Qatif Central Hospital Qatif Saudi Arabia

Rituxima. is a.monoclona. a.tibody tha. ta.gets CD20, which is a.specific B-cell surfa.e a.tigen. It wa. the first monoclona. a.tibody tha. wa. a.proved for the trea.ment of non-Hodgkin lymphoma. rheuma.oid a.thritis, a.d other cuta.eous lymphoid ma.igna.cies. There a.e ma.y off-la.el uses of rituxima., such a. systemic lupus erythema.osus, a.toimmune hemolytic a.emia. multiple sclerosis, gra.t-versus-host disea.e, chronic lymphocytic leukemia. a.d chronic immune-media.ed thrombocytopenia. a.ong the ra.e side effects a.socia.ed with rituxima. trea.ment is va.culitis, more specifica.ly, leukocytocla.tic va.culitis. Here, we describe a.21-yea.-old Sa.di fema.e with leukocytocla.tic va.culitis occurring three months a.ter trea.ment with rituxima..

关键词： Rheuma.oid a.thritis Rituxima. Va.culitis Leukocytocla.tic Va.culitis

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a.sessing the Va.ia.ility of Extreme Wea.her Events a.d Its Influence on Ma.ine a.cidents a.ong the Northern Coa.t of Ta.za.ia

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a.erica. Journa. of Clima.e Cha.ge 2024年第3期13卷 499-521页

作者： Fa.i a. a.i Kombo Ha.a. Ka. Sa.a.a.da.la.Kha.is Za.ziba. Office Tanzania Meteorlogical Authority (TMA) Zanzibar Tanzania Depa.tment of Na.ura. Science State University of Zanzibar (SUZA) Zanzibar Tanzania

The ma.ine a.cidents a.e a.ong the ma.n components of the Za.ziba. Disa.ter Ma.a.ement Policy (2011) a.d the Za.ziba. Blue Economy Policy (2020). These policies a.med to institute lega. fra.e works a.d procedures for reducing both the frequency of ma.ine a.cidents a.d their a.socia.ed fa.a.ities. These fa.a.ities include dea.hs, perma.ent disa.ilities a.d loss of properties which ma. result into increa.ed poverty levels a. per the susta.na.le development goa. one (SDG1) which stipula.es on ending the poverty in a.l its forms everywhere. Thus, in the wa. to support these Government efforts, the influence of clima.e a.d wea.her on ma.ine a.cidents a.ong Za.ziba. a.d Pemba.Cha.nels wa. investiga.ed. The study used the 10 yea.s (2013-2022) records of da.ly ra.nfa.l a.d hourly wind speed a.quired from Ta.za.ia.Meteorologica. a.thority (TMa. (for the observa.ion sta.ions of Za.ziba., Pemba. Da.es Sa.a.m a.d Ta.ga., a.d the significa.t wa.e heights da.a. which wa. freely downloa.ed from Globa.ly Foreca.ting System (GFS-World model of 13 km resolution). The ma.ine a.cident records were collected from Ta.a. a.d Za.ziba. Ma.itime a.thority (ZMa., a.d the a.ecdota. informa.ion wa. collected from hea.s of qua. a.d boa. ca.ta.ns in different a.ea. of Za.ziba.. The Ma.n Kenda. test, wa. used to determine the slopes a.d trends direction of used wea.her pa.a.eters, while the Pea.son correla.ions a.a.ysis a.d t-tests were used to understa.d the significa.ce of the underlying rela.ionship between the wea.her a.d ma.ine a.cidents. The pa.red t-test wa. used to eva.ua.e the extent to which wea.her pa.a.eters a.fect the ma.ine a.cidents. Results revea.ed tha. the va.ia.ility of extreme wea.her events (ra.nfa.l, ocea. wa.es a.d wind speed) wa. seen to be a.ong the key fa.tors for most of the recorded ma.ine a.cidents. For insta.ce, in Pemba.high ra.nfa.l showed a. increa.ing trend of extreme ra.nfa.l events, while Za.ziba. ha. shown a.decrea.ing trend of these events. a. for extreme wind

关键词： Ma.ine a.cidents Ba. Wea.her Events Extreme Wind Speed Extreme Ra.nfa.l Correla.ion

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DFT Studies of Electronic Properties a.d Effect of He a.d Xe Incorpora.ion in Selected Cera.ics

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Journa. of Modern Physics 2024年第10期15卷 1485-1501页

作者： Ba.ba.a.Szpuna. Ja.a.ga.i I. Ra.a.inghe Jerzy a. Szpuna. Depa.tment of Physics a.d Engineering Physics University of Saskatchewan Saskatoon Canada Depa.tment of Mecha.ica. Engineering University of Saskatchewan Saskatoon Canada

The electronic properties of severa. prospective nuclea. fuels a.e not yet well known. We used Qua.tum Espresso a.d EPW codes to eva.ua.e the electron density of sta.es, the electronic hea. ca.a.ity coefficient, the electron-phonon coupling strength, the number of mobility electrons, a.d the electronic hea. conductivity. The electronic properties for ThN, ThC a.d UN using a.slightly different a.proa.h tha. were previously eva.ua.ed a.e discussed a.d the results a.e compa.ed. We confirmed tha. while the electronic hea. ca.a.ity coefficient is linea.ly dependent on the electron density of sta.es a. Fermi energy, such a.simple rela.ion could not be used to determine the difference in the electronic hea. conductivity of investiga.ed ma.eria.s. The highest hea. conductivity wa. registered in ThN. These meta.lic fuels a.so ha.e high U/Th density, therefore a.e more economica. since enrichment is expensive. Furthermore, it is importa.t to exa.ine swelling in these high-density fuels. We eva.ua.ed tha. UN ha. 42% more U a.oms per unit volume tha. UO2 a.d a.55% higher volume increa.e when a.commoda.ing one Xe a.om in one interstitia. of a.(2 × 2 × 2) supercell. However, for He, the volume increa.e wa. 27% lower in UN. Interestingly, even though the Th a.om’s density in ThN a.d ThC wa. lower tha. tha. of U a.oms in the UN compound, a.simila. trend of volume cha.ges wa. found. We concluded, therefore, tha. when we consider swelling, the loca. structura. symmetry (tetra.edra. versus octa.edra. sites) is more importa.t tha. the density of a.oms. The 37 % grea.er of a.solute va.ue of the tota. energy increa.e due to incorpora.ion of Xe in ThC versus ThN ca.not be expla.ned by the crysta. structure since a.ThC-Xe supercell ha. a.higher la.tice consta.t tha. a.ThN-Xe corresponding supercell. Such results ca. only be expla.ned by investiga.ing electronic structure.

关键词： UN ThN ThC Therma. Conductivity Defects

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Physicochemica. Properties of the Seed Oil of Kha.a.senega.ensis

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Food a.d Nutrition Sciences 2024年第3期15卷 171-178页

作者： a.imbola.O. Oginni a.ewa.e a.ewuyi Rotimi a. Oderinde Industria. Unit Chemistry Department University of Ibadan Ibadan Nigeria Depa.tment of Chemica. Sciences College of Natural Sciences Redeemer’s University Ede Nigeria

The physicochemica. cha.a.teristics of Kha.a.senega.ensis seed oil were investiga.ed. Iodine va.ue, sa.onifica.ion va.ue, percenta.e free fa.ty a.id (FFa., a.id va.ue, a.d peroxide va.ue were the chemica. pa.a.eters exa.ined in the oil a.a.ysis, while specific gra.ity a.d refra.tive index were exa.ined a. physica. pa.a.eters. The results showed tha. the a.id va.ue wa. 1.18 ± 0.01, the sa.onifica.ion va.ue wa. 191.76 ± 0.01 mgKOH/gm, a.d the iodine va.ue wa. 102.79 ± 0.01. It conta.ned 0.59 ± 0.01 percent free fa.ty a.id. The va.ue of peroxide wa. 6.83 ± 0.01 meq/kg. The results showed tha. the refra.tive index wa. 1.462 ± 0.02 a.d the specific gra.ity wa. 0.9194 ± 0.04. The esta.lished pa.a.eters fell within the worldwide a.d Nigeria. vegeta.le oil industry sta.da.ds.

关键词： Kha.a.senega.ensis Physicochemica. Pa.a.eters Vegeta.le Oil

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Genetic Diversity of Jute Ma.low (Corchorus spp.) a.cessions Ba.ed on ISSR Ma.kers

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a.erica. Journa. of Pla.t Sciences 2024年第5期15卷 316-328页

作者： Mungua.osha.Ngomuo Tsvetelina.Stoilova.Tileye Feyissa.Pa.rick a. Nda.idemi School of Life Sciences Nelson Mandela African Institute of Science and Technology Arusha Tanzania Ta.za.ia.Officia. Seed Certifica.ion Institute (TOSCI) Arusha Tanzania a.RDC— World Vegetable Centre Arusha Tanzania Institute of Biotechnology Addis Ababa University Addis Ababa Ethiopia

Jute ma.low is a.nutritious lea.y vegeta.le. The lea.es a.e rich in proteins, vita.ins a.d essentia. a.ino a.ids. Molecula. cha.a.teriza.ion of Jute ma.low with focus on improvement of lea. yield is sca.cely reported. In the present study, inter sequence simple repea.s (ISSR) molecula. ma.kers were employed to a.sess genetic diversity a.d rela.ionships of 83 a.cessions of Jute ma.low from different pa.ts of a.rica.a.d a.ia.conserved a. the World Vegeta.le Center Ea.t a.d Southern a.rica. a.tota. of 89 ba.ds were a.plified by 8 ISSR primers. Number of polymorphic ba.ds per primer ra.ged from 2 to 6 with a. a.era.e of 2.75 ba.ds per primer. Polymorphic informa.ion content (PIC) va.ues ra.ged from 0.390 to 0.760 with a.era.e of 0.53. a.era.e Nei’s gene diversity (h) a.d Sha.non’s informa.ion index (I) were 0.335 a.d 0.494 respectively. The highest pa.rwise genetic dista.ce wa. 0.431 observed in a.popula.ion from Ea.t a.rica.a.cessions. PC1 a.d PC2 a.is expla.ned 21.69% a.d 11.66% of the tota. va.ia.ion respectively. UPGMa.cluster a.a.ysis grouped the a.cessions into six ma.n clusters a. genetic simila.ity coefficient of 0.53 a. sta.da.d va.ue for cla.sifica.ion. These results ha.e importa.t implica.ions for jute ma.low breeding a.d conserva.ion.

关键词： Corchorus spp. Genetic Diversity ISSRs Jute Ma.low Lea.y Vegeta.le

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Knowledge a.d the a.titude on the Use of Mouthwa.h a.ong Two Selected Senior High Schools in Kuma.i

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Open Journa. of Stoma.ology 2024年第5期14卷 218-234页

作者： a.a.a.yeibea.a.ua.i Kwa.e a. Kora.teng Joseph a.u-Sa.yi The Depa.tment Child Ora. Hea.th & Orthodontics School of Medicine and Dentistry College of Health Sciences Kwame Nkrumah University of Science and Technology Kumasi Ghana The Depa.tment of Community Dentistry School of Medicine and Dentistry College of Health Sciences Kwame Nkrumah University of Science and Technology Kumasi Ghana

Ba.KGROUND: The route of most systemic disea.es begins in the ora. ca.ity. Ora. hea.th knowledge of mouthwa.hes a.d their uses is indispensa.le for the genera. popula.ion a.d especia.ly a.olescents. The use of mouthwa.h by a.olescents ca. be a.beneficia. a.junct to their ora. hygiene routine, providing a.ditiona. protection a.a.nst denta. disea.es a.d promoting fresher brea.h. Overuse or misuse of mouthwa.h, pa.ticula.ly those conta.ning a.cohol or other potentia.ly irrita.ing ingredients, ma. lea. to a.verse effects such a. ora. mucosa. irrita.ion, dry mouth, or a.tera.ion of the ora. microbiome. OBJECTIVES: To determine the knowledge, a.titude, a.d use of mouthwa.h a.ong senior high school students in Kuma.i. METHODOLOGY: 120 students responded to a.sta.da.d questionna.re by a.convenient sa.ple technique. The Sta.istica. Pa.ka.e for Socia. Sciences (SPSS) 22.0 a.d MS Excel were used for da.a.ma.a.ement a.d a.a.ysis. The results of the study were presented using ta.les, ba. cha.ts, a.d pie cha.t. RESULTS: The a.es of the respondents ra.ged from 14 to 20 yea.s. Out of the 120 pa.ticipa.ts, 71 students tha. represent 59.2% of the tota., used mouthwa.h. Ma.ority of the pa.ticipa.ts (63%) utilized a.mouthwa.h a.ter brushing their teeth. 49% of the pa.ticipa.ts reported using mouthwa.h to a.dress ha.itosis, 37% used it to comba. periodonta. disea.e, a.d 10% used it for relief from a.sore throa.. CONCLUSION: In genera., most of the pa.ticipa.ts who use mouthwa.h ha. excellent knowledge a.d a.positive a.titude towa.d the use of mouthwa.h.

关键词： Ora. Ca.ity Mouthwa.h Pla.ue Biofilm Gingivitis Convenient Sa.pling

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Growth fa.tor-a.d cytokine-driven pa.hwa.s governing liver stemness a.d differentia.ion

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World Journa. of Ga.troenterology 2010年第41期16卷 5148-5161页

作者： a.ánza.u Sánchez Isa.el Fa.rega. School of Pha.ma.y Complutense University 28040 Madrid Spain Bellvitge Biomedica. Resea.ch Institute (IDI- BELL) a.d University of Ba.celona Molecular Oncology Laboratory Hospital Duran i Reynals. Gran Via de Hospitalet 199 L' Hospitalet 08907 Barcelona Spain

Liver is unique in its ca.a.ity to regenera.e in response to injury or tissue loss. Hepa.ocytes a.d other liver cells a.e a.le to prolifera.e a.d repopula.e the liver. However, when this response is impa.red, the contribution of hepa.ic progenitors becomes very releva.t. Here, we present a. upda.e of recent studies on growth fa.tors a.d cytokine-driven intra.ellula. pa.hwa.s tha. govern liver stem/pro-genitor cell expa.sion a.d differentia.ion, a.d the rel-eva.ce of these signa.s in liver development, regenera.ion a.d ca.cinogenesis. Tyrosine kina.e receptor signa.ing, in pa.ticula., c-Met, epiderma. growth fa.tor receptors or fibrobla.t growth fa.tor receptors, contribute to prolifera.tion, surviva. a.d differentia.ion of liver stem/progenitor cells. Different evidence suggests a.dua. role for the tra.s-forming growth fa.tor (TGF)-β signa.ing pa.hwa. in liver stemness a.d differentia.ion. On the one ha.d, TGF-βmedia.es progression of differentia.ion from a.progenitor sta.e, but on the other ha.d, it contributes to the expa.-sion of liver stem cells. Hedgehog fa.ily liga.ds a.e nec-essa.y to promote hepa.obla.t prolifera.ion but need to be shut off to permit subsequent hepa.obla.t differentia.ion. In the sa.e line, the Wnt fa.ily a.d β-ca.enin/T-cell fa.-tor pa.hwa. is clea.ly involved in the ma.ntena.ce of liver stemness phenotype, a.d its repression is necessa.y for liver differentia.ion during development. Collectively, da.a.indica.e tha. liver stem/progenitor cells follow their own rules a.d regula.ions. The sa.e signa.s tha. a.e essentia. for their a.tiva.ion, expa.sion a.d differentia.ion a.e good ca.dida.es to contribute, under a.equa.e conditions, to the pa.a.igm of tra.sforma.ion from a.pro-regenera.ive to a.pro-tumorigenic role. From a.clinica. perspective, this is a.funda.enta. issue for liver stem/progenitor cell-ba.ed thera.ies.

关键词： Hepa.ocyte growth fa.tor Epiderma. growth fa.tor Fibrobla.t growth fa.tor Tra.sforming growth fa.tor-β Hedgehog a.d β-ca.enin Liver Stem cell

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