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Pa.dia.ric s.rgica. Outrea.h to Pa.ua.New Guinea. Initia. Experience

Interna.iona. Journa. of Clinica. Medicine 2018年第9期9卷 697-702页

作者： R. Ra. Ja.k Mulu a. s. jacobsen Depa.tment of Pa.dia.ric s.rgery K K Women’s & Children’s Hospital Singapore Pa.dia.ric s.rgica. Unit Port Moresby General Hospital Korobosea Papua New Guinea

This.is.a.report of our ea.ly experience in es.a.lis.ing a.Pa.dia.ric s.rgica. outrea.h progra. to Pa.ua.New Guinea.(PNG) to build ca.a.ity a.d improve ca.e. a.Pa.dia.ric s.rgica. outrea.h mis.ion wa. initia.ed a.out 4 yea.s.a.o in colla.ora.ion with s.nghea.th a.d PNG a.ong with the multidis.iplina.y tea. of hea.th ca.e profes.iona.s.from Ca.diology, Ca.diothora.ic s.rgery, Orthopa.dics. Urology, Pla.tics.a.d a.a.s.hes.a. On ea.h mis.ion trip of 4 - 7 da.s.dura.ion, s.nghea.th doctors.s.pervis. or perform s.rgeries.for complex ca.es. conduct pa.ient cons.lta.ions.a.d give lectures.to impa.t knowledge a.d tra.s.er s.ills.to the loca. hea.th ca.e community in PNG. In a.dition, a.6 - 12 months.tra.ning progra. in s.nga.ore for PNG doctors.ha. been s.a.ted. For complex ca.es.which ca.not be ma.a.ed in PNG, there is.provis.on for tra.s.er of pa.ients.to s.nga.ore under KKROK fund for further trea.ment. s. fa. 4 mis.ion trips.ha.e been conducted in pa.t 4 yea.s.for pa.dia.ric s.rgica. unit in Port Mores.y Genera. Hos.ita. of PNG focus.ing on tea.hing a.d tra.ning of loca. Pa.dia.ric s.rgeons. Ba.ed on eva.ua.ion of the s.nghea.th medica. tea., there is.s.vere s.orta.e of medica. ma.power, s.rgica. s.ill a.d s.ecia.is.d expertis.. Due to la.k of intens.ve ca.e fa.ility, a.equa.e medica.ions.a.d proper medica. equipment in the hos.ita., there a.e ma.y conditions.being left untrea.ed ca.s.ng high morbidity a.d morta.ity a.ong infa.ts.a.d neona.es. s.ch huma.ita.ia. work ins.ires.s.nghea.th towa.ds.its.globa. hea.th mis.ion of promoting hea.th equity in res.onding to the medica. needs.of PNG through tra.ning a.d levera.ing on s.rength through pa.tners.ip. In a.dition, our doctors.ga.n inva.ua.le lea.ning from the expos.re, hone their s.ill a. they trea. a.divers.ty of ca.es.a.d a.e innova.ive in their trea.ment options.by working in a. environment with limited res.urces.

关键词： Pa.dia.ric s.rgery Outrea.h Pa.ua New Guina.

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Gottfried Konecny:The photogra.metric a.d remote s.ns.ng trend s.tter

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Geo-s.a.ia. Informa.ion s.ience 2021年第1期24卷 13-21,I0004页

作者： Ka.s.en jacobsen Ins.itute of Photogra.metry a.d Geoinforma.ion Leibniz University HannoverHannoverGermany

There a.e va.ious.publica.ions.on the 90th birthda. of Gottfried *** involvement in the Interna.iona. s.ciety for Photogra.metry a.d Remote s.ns.ng(Is.Rs.is.pa.ticula.ly des.ribed by ***,his.forwa.d-oriented impuls.s.in res.a.ch a.d development a. the former Ins.itute for Photogra.metry a.d Engineering s.rvey of the(Technica.)Univers.ty of Ha.nover,toda. Ins.itute for Photogra.metry a.d Geoinforma.ion,Leibniz Univers.ty Ha.nover,a.d s.me of his.a.tivities.s.pporting developing a.d other countries.by given s.ortterm cours.s.a.e *** Konecny wa. a.wa.s.one of the firs. in pus.ing new *** the a.a.ytica. plotter a./C-3,he introduced a.a.ytica. photogra.metry in *** on his.experience with this.not rea.ly opera.iona. vers.on,he induced the compa.y Zeis. to develop the firs. rea.ly opera.iona. a.a.ytica. plotter Pla.icomp,which res.lted in the end of a.a.og photogra.metric devices.a.d their *** the invita.ion of Gilbert Hobrough,a.ma.nly ha.dwa.e-ba.ed ima.e correla.or wa. developed for the a./C-3 in Ha.nover which a.ticipa.ed ma.y of toda.’s.*** Konecny initia.ed remote s.ns.ng in *** on his.propos.0} with the Metric Ca.era.Flight on s.a.ela.,the then highes. res.lution civil s.ereos.opic s.a.e ima.es.a.a.la.le were *** limited computer performa.ce a. his.ins.itute,a.digita. s.ereo plotter wa. developed,us.ng ha.dwa.e components.from the coopera.ing s.edis. compa.y Context Vis.on,long before digita. s.ereo works.a.ions.with increa.ed a.d a.forda.le computer ca.a.ity were ***,in the a.ea.of GIs.he too,pus.ed development in colla.ora.ion with compa.ies.a.d *** before the end of his.time a. hea. of the ins.itute,a.d more s. a.ter he beca.e emeritus.profes.or,he s.a.ted a.s.ries.of educa.iona. works.ops.pa.ticula.ly in developing countries.but a.s. other countries.to s.pport the development of photogra.metry,remote s.ns.ng a.d *** prom

关键词： initia.ed gra.me ha.dwa.e

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Two-dimens.ona. ferroelectrics.from high throughput computa.iona. s.reening

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npj Computa.iona. Ma.eria.s 2023年第1期9卷 1901-1911页

作者： Ma.s.Krus. Urko Petra.a.da.Morten N.Gjerding Ka.s.en W.jacobsen Kris.ia. s.Thyges.n Thoma. Ols.n Ca.D Department of PhysicsTechnical University of DenmarkDK-2800 Kongens LyngbyDenmark

We report a.high throughput computa.iona. s.a.ch for two-dimens.ona. ferroelectric *** s.a.ting point is.252 pyroelectric ma.eria.s.from the computa.iona. 2D ma.eria.s.da.a.a.e(C2DB)a.d from thes. we identify 63 *** pa.ticula. we find 49 ma.eria.s.with in-pla.e pola.iza.ion,8 ma.eria.s.with out-of-pla.e pola.iza.ion a.d 6 ma.eria.s.with coupled in-pla.e a.d out-of-pla.e *** of the known 2D ferroelectrics.a.e recovered by the s.reening a.d the fa. ma.ority of the predicted ferroelectrics.a.e known a. bulk va. der Wa.ls.bonded compounds.which ma.es.them a.ces.ible by direct *** roughly 25%of the ma.eria.s.we find a.meta.ta.le s.a.e in the non-pola. s.ructure,which ma. imply a.firs. order tra.s.tion to the pola. ***,we lis. the ma.netic pyroelectrics.extra.ted from the C2DB a.d focus.on the ca.e of Va.P2s.6,which exhibits.a.three-s.a.e s.itcha.le pola.iza.ion vector tha. is.s.rongly coupled to the ma.netic excita.ion s.ectrum.

关键词： ma.eria.s pola.iza.ion pla.e

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N-clus.er correla.ions.in four-a.d five-dimens.ona. percola.ion

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Frontiers.of phys.cs 2020年第4期15卷 5-16页

作者： Xia.-Jun Ta. You-Jin Deng Jes.er Lykke jacobsen Hefei Na.iona. La.ora.ory for Phys.ca. s.iences.a. Micros.a.e a.d Depa.tment of Modern Phys.cs University of Science and Technology of ChinaHefei 230026China Ca. Center for Ercellence a.d s.nergetic Innova.ion Center in Qua.tun Informa.ion a.d Qua.tum Phys.cs University of Science and Technology of ChinaHefei 230026China La.ora.oire de Phys.que de I'Ecole Norma.e s.perieure ENSUniversite PSLCNRSSorbonne UniversiteUniversite de ParisParisFrance s.rbnne Univers.te Eecole Normale SuperieureCNRSLaborutoire de Physique(LPENS)75005 ParisFrance Ins.itut de Phys.que Theorique Universite Paris SaclayCEACNRS91191 Gif-sur-YvetteFrance

We s.udy N-clus.er correla.ion functions.in four-a.d five-dimens.ona.(4D)a.d 5D)bond percola.ion by extens.ve Monte Ca.lo *** reformula.e the tra.s.er Monte Ca.lo a.gorithm for percola.ion[***.E 72,016126(2005)]us.ng the dis.oint-s.t da.a.s.ructure,a.d s.mula.e a.cylindrica. geometry Ld^-1×∞,with the linea. s.ze up to L=512 for 4D a.d 128 for *** determine with 1 high precis.on a.l pos.ible N-clus.er exponents.for N=2 a.d 3,a.d the univers.0} a.plitude for a.loga.ithmic correla.ion *** the s.mmetric correla.or with N=2,we obta.n the correla.ion-length critica. exponent a. 1/v=1.4610(12)for 4D a.d 1/v=1.737(2)for 5D,s.gnifica.tly improving over the exis.ing *** for the other exponents.a.d the univers.0} loga.ithmic a.plitude ha.e not been reported before to our *** work demons.ra.es.the va.idity of loga.ithmic conforma. field theory a.d a.ds.to the growing knowledge for high-dimens.ona. percola.ion.

关键词： critica. exponents percola.ion loga.ithmic conforma. field theory Monte Ca.lo a.gorithm

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Ca. rega.enos.n pha.ma.ologic s.ECT be performed effectively in pa.ients.with left bundle bra.ch block or pa.ed rhythm pa.ients. a.retros.ective compa.is.n to a.enos.ne s.ECT

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World Journa. of Ca.diova.cula. Dis.a.es 2013年第2期3卷 222-227页

作者： Guruna.tha. Pa.a.i a.rthee s. Ka.thikeya. jacobsen Gordon Ka.thik a.a.tha.ubra.a.ia. Depa.tment of Interna. Medicine McLaren/Michigan State University Flint USA Hea.t a.d Va.cula. Ins.itute Henry Ford Hospital Detroit USA

Purpos.: Rega.enos.n (REG) is.currently becoming the s.res. a.ent of choice in pa.ients.undergoing pha.ma.ologic s.ngle photon emis.ion computed tomogra.hy (s.ECT). However, in pa.ients.with left bundle bra.ch block (LBBB) a.d ventricula. pa.ed rhythm (VPR), hes.ta.ion exis.s.a.ongs. clinicia.s.to us. REG-s.ECT due to the concern tha. the increa.ed hea.t ra.e could ca.s. fa.s. pos.tive s.ECT res.lts. We s.ught to eva.ua.e the compa.a.ility of a.s.ECT a.d REG-s.ECT in pa.ients.with LBBB a.d VPR. Methods. Retros.ective s.udy of 30 pa.ients.who s.rved a. their own controls. a.l 30 pa.ients.who underwent REG-s.ECT (Grp 1) were compa.ed to their prior a.s.ECT (Grp 2) done within two yea.s.prior to REG-s.ECT. Hea.t ra.e (HR) a.d blood pres.ure (BP) pa.a.eters. ECG, s.res. perfus.on a.d ga.ed va.ia.les. s.ECT is.hemia. a.d s.de-effects.were eva.ua.ed. s.a.is.ica. s.gnifica.ce wa. s.t a. P s.lts. Grp 1 a.d Grp 2 were compa.a.le in hemodyna.ic pa.a.eters.with increa.e in HR a.d decrea.e in s.s.olic a.d dia.tolic BP with a.minis.ra.ion of a.enos.ne a.d REG s.res. a.ents. However, there were no s.gnifica.t differences.found in hemodyna.ic pa.a.eters.a.d II degree a. block between the groups. a.l norma. a.s.ECT were found to be norma. with REG-s.ECT. No differences.could be found between the two groups.a.ong s.ECT pa.a.eters. Mus.le pa.n wa. s.gnifica.tly higher in REG (10.0% vs. 0.0%, P = 0.083) a.d s. wa. the us. of a.inophylline (16.7% vs. 0.0%, P = 0.025) to relieve the s.de-effect. Conclus.on: REG-s.ECT ca. be a.minis.ered in pa.ients.with LBBB a.d VPR pa.ients.ba.ed on fa.ora.le a.d compa.a.le hemodyna.ic res.ons.s.a.d a.rhythmia.occurrences.to a.s.ECT. REG-s.ECT ca. a.s. be us.d for a.equa.e interpreta.ion of pres.nce or a.s.nce of s.ECT is.hemia.pa.ticula.ly in the La. territory without a.y concern for fa.s. pos.tive perfus.on defects.

关键词： Rega.enos.n s.ngle Photon Emis.ion Computed Tomogra.hy Left Bundle Bra.ch Block Ventricula. Pa.ed Rhythm a.enos.ne Fa.s. Pos.tive s.ECT

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High-throughput computa.iona. s.reening for twodimens.ona. ma.netic ma.eria.s.ba.ed on experimenta. da.a.a.es.of three-dimens.ona. compounds

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npj Computa.iona. Ma.eria.s 2020年第1期6卷 350-361页

作者： Da.iele Torelli Ha.eel Mous.a.a.Ka.s.en W.jacobsen Thoma. Ols.n Computa.iona. a.omic-s.a.e Ma.eria.s.Des.gn(Ca.D) Department of PhysicsTechnical University of DenmarkDK-2800 Kgs.LyngbyDenmark

We perform a.computa.iona. s.reening for two-dimens.ona.(2D)ma.netic ma.eria.s.ba.ed on experimenta. bulk compounds.pres.nt in the Inorga.ic Crys.a. s.ructure Da.a.a.e a.d Crys.a.logra.hy Open Da.a.a.e.a.recently propos.d geometric des.riptor is.us.d to extra.t ma.eria.s.tha. a.e exfolia.le into 2D deriva.ives.a.d we find 85 ferroma.netic a.d 61 a.tiferroma.netic ma.eria.s.for which we obta.n ma.netic excha.ge a.d a.is.tropy pa.a.eters.us.ng dens.ty functiona. *** the ea.y-a.is.ferroma.netic ins.la.ors.we ca.cula.e the Curie tempera.ure ba.ed on a.fit to cla.s.ca. Monte Ca.lo s.mula.ions.of a.is.tropic Heis.nberg *** find good a.reement with the experimenta.ly reported Curie tempera.ures.of known 2D ferroma.nets.a.d identify 10 potentia.ly exfolia.le 2D ferroma.nets.tha. ha.e not been reported *** a.dition,we find 18 ea.y-a.is.a.tiferroma.netic ins.la.ors.with s.vera. compounds.exhibiting very s.rong excha.ge coupling a.d ma.netic a.is.tropy.

关键词： ma.netic compounds ferroma.netic

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a.erra.t cytokine milieu a.d s.gna.ing a.fect immune cell phenotypes.a.d functions.in tuberculos.s.pa.hology:Wha. ca. we lea.n from this.phenomenon for a.plica.ion to infla.ma.ory s.ndromes.

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Cellula. & Molecula. Immunology 2021年第8期18卷 2062-2064页

作者： Ernes. a.a.kwa. Julia.s.yfa.th Richa.d Phillips.Ma.c jacobsen Depa.tment of Genera. Pedia.rics Medical FacultyUniversity Hospital DüsseldorfHeinrich-Heine-UniversityDüsseldorfGermany Depa.tment of Medica. Dia.nos.ics College of Health SciencesKwame Nkrumah University of Science and Technology(KNUST)KumasiGhana Depa.tment of Medicine School of Medicine and DentistryCollege of Health SciencesKwame Nkrumah University of Science and Technology(KNUST)KumasiGhana Kuma.i Centre for Colla.ora.ive Res.a.ch in Tropica. Medicine(KCCR) KumasiGhana

Our previous.s.udy publis.ed in Cellula.&Molecula. Immunology(Ha.ling et a..1)des.ribed a.erra.t immunologica. fea.ures.in the pa.hogenes.s.of ***,we provided evidence s.pporting a. impa.t cha.n rega.ding a.erra.t high interleukin(IL)-6 a.d IL-10 cytokine expres.ion a.d res.ective receptor s.gna.ing a.fecting T-cell functions.in a.ute *** s.a.3 phos.horyla.ion,high expres.ion of its.key regula.or s.ppres.or of cytokine s.gna.ing(s.Cs.3 a.d s.onta.eous.IL-6/IL-10 s.cretion cha.a.terized CD4^(+)T cells.from tuberculos.s.pa.ients.

关键词： tuberculos.s cytokine s.a.3

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Multi-s.a.e pola.is.0}ion phenomena

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Light(s.ience & a.plica.ions. 2016年第1期5卷 810-818页

作者： Vla.imir Ka.a.hnikov s.rgey V s.rgeyev Gunna. jacobsen s.rgei Popov s.rgei K Turits.n a.PT Aston UniversityBirminghamWest Midlands B47ETUK a.reo Electrum 236SE-16440KistaSweden Roya. Ins.itute of Technology(KTH) SE-1640StockholmSweden

Multi-s.a.e methods.tha. s.pa.a.e different time or s.a.ia. s.a.es.a.e a.ong the mos. powerful techniques.in phys.cs.es.ecia.ly in a.plica.ions.tha. s.udy nonlinea. s.s.ems.with *** the time s.a.es.nois. a.d perturba.ion)a.e of the s.0}e order,the s.a.es.s.pa.a.ion becomes.***,the multi-s.a.e a.proa.h ha. to be modified to cha.a.teris. a.va.iety of nois.-induced ***,ba.ed on s.ocha.tic modelling a.d a.a.ytica. s.udy,we demons.ra.e in terms.of the fluctua.ion-induced phenomena.a.d Hurs. R/s.a.a.ys.s.metrics.tha. the ma.ching s.a.es.of ra.dom birefringence a.d pump–s.gna. s.a.es.of pola.is.0}ion intera.tion in a.fibre Ra.a. a.plifier res.lts.in a.new ra.dom birefringence-media.ed phenomenon,which is.s.mila. to s.ocha.tic *** obs.rved phenomenon,a.a.t from the funda.enta. interes.,provides.a.ba.e for a.va.cing multi-s.a.e methods.with a.plica.ion to different coupled nonlinea. s.s.ems.ra.ging from la.ers.multimode,mode-locked,ra.dom,etc.)to na.os.ructures.light-media.ed conforma.ion of molecules.a.d chemica. rea.tions.Brownia. motors.etc.).

关键词： fibre Ra.a. a.plifier multi-s.a.e methods pola.is.0}ion s.ocha.tic ca.cula.ions

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Los. of Ps.94 expres.ion is.a.s.cia.ed with ea.ly Ps.0}recurrence a.d deteriora.es.outcome of PTEN deleted pros.a.e ca.cers

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Ca.cer Biology & Medicine 2019年第2期16卷 319-330页

作者： a.drea. M. Luebke a.i a.ta.chi-Tehra.i Ja. Meiners.Cla.dia.Hube-Ma.g Da.ma. s. La.g Ma.tina.Kluth Ma.ia.Chris.ina.Ts.urla.is.s.0}a. Minner Rona.d s.mon Guido s.0}ter Fra.zis.a.Bus.heck Fra.k jacobsen a.drea.Hins.h s.efa. s.eurer Thors.en s.hlomm Ha.twig Hula.d Ma.kus.Gra.fen a.exa.der Ha.s. Ha.s.Heinzer Till s. Cla.ditz Eike Bura.dt Wa.dema. Wilcza. Doris.Hoflma.er Ins.itute of Pa.hology University Medical Center Hamburg-Eppendorf Hamburg 20246 Germany Genera. Visceral and Thoracic Surgery Department and Clinic University Medical Center Hamburg-Eppendorf Hamburg 20246 Germany Depa.tment of Urology Charite-Universitatsmedizin Berlin Berlin 10117 Germany Ma.tini-Clinic Prostate Cancer Center University Medical Center Hamburg-Eppendorf Hamburg 20246 Germany

Objective: Pros.a.e s.cretory protein of 94 a.ino a.ids.Ps.94) is.a.ta.get gene of the EZH2 tra.s.riptiona. repres.or a.d is.often downregula.ed in pros.a.e ca.cer;however, its.prognos.ic va.ue is.***: Immunohis.ochemica. a.a.ys.s.of a.tis.ue microa.ra. of 12, 432 pros.a.e ca.cer s.ecimens.wa. performed to eva.ua.e Ps.94 expres.ion. Correla.ion of Ps.94 expres.ion with tumor phenotype, pa.ient prognos.s. TMPRs.2:ERG fus.on s.a.us. EZH2 expres.ion a.d PTEN deletion wa. ***: Ps.94 expres.ion wa. increa.ed in benign pros.a.ic hyperpla.ia.however, it wa. downregula.ed in 48% a.d nega.ive in42% of the 9, 881 interpreta.le pros.a.e ca.cer s.ecimens. The los. of Ps.94 expres.ion wa. invers.ly correla.ed to EZH2 expres.ion(P a.d la.gely unrela.ed to the ERG s.a.us. but s.rongly correla.ed with high Glea.on gra.e, a.va.ced tumor s.a.e, a.d noda. meta.ta.is.P a.h). The fra.tion of Ps.94-nega.ive ca.cer s.ecimens.increa.ed from 40% in pT2 to 52%in pT3 b-pT4(P a.d from 40% in Glea.on 3+3 = 6 to 46% in Glea.on 4+3 = 7 a.d 60% in Glea.on ≥4+4 = 8(P s. of Ps.94 wa. linked to ea.ly pros.a.e-s.ecific a.tigen recurrence, but with little a.s.lute effect(P a.ditiona. prognos.ic impa.t in ca.cer s.ecimens.with PTEN deletion. Los. of Ps.94 deteriora.ed prognos.s.of ca.cer pa.ients.with PTEN deletion by more tha. 10%(P a.ion of PTEN deletion a.d Ps.94 los. provided independent prognos.ic informa.ion tha. wa. obs.rved in s.vera. s.bgroups.defined by cla.s.ca. a.d qua.tita.ive Glea.on ***: The res.lts.of our s.udy s.gges. tha. combined Ps.94/PTEN a.a.ys.s.ca. be potentia.ly us.d in the clinica. prognos.s.of pros.a.e ca.cer.

关键词： Ms.B Ps.94 PTEN pros.a.e ca.cer tis.ue microa.ra.

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Globa. hea.th educa.ion for the pos.-pa.demic yea.s.pa.ity,people,pla.et,priorities.a.d pra.tices

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Globa. Hea.th Res.a.ch a.d Policy 2022年第1期7卷 585-591页

作者： Ka.hryn H.jacobsen Ca.yl E.Wa.gett Depa.tment of Hea.th s.udies University of RichmondRichmondVAUSA Depa.tment of Globa. Hea.th s.udies Allegheny CollegeMeadvillePAUSA

Globa. hea.th degree progra.s.a.e now offered by ins.itutions.of higher educa.ion in mos. world *** on our review of the curricula.for ma.y of thes. progra.s.we identified five doma.ns.tha. a.e centra. to current globa. hea.th educa.ion.“Pa.ity”empha.izes.hea.th equity a. the ultima.e goa. of globa. hea.th.“People”compris.s.the s.cia.,economic,cultura.,a.d politica. contributors.to hea.th a.d a.ces. to medica. ca.e for individua.s.a.d communities.“Pla.et”encompa.s.s.va.ious.a.pects.of globa.iza.ion a.d environmenta. hea.th tha. a.fect popula.ion hea.th.“Priorities.a.d“pra.tices.include the va.ues.da.a.a.d tools.us.d to des.gn,implement,a.d eva.ua.e pa.tners.ips.policies.progra.s.a.d other globa. hea.th interventions.in countries.of a.l income *** pa.demic is.likely to increa.e s.udent dema.d for globa. hea.th educa.ion from the undergra.ua.e through the gra.ua.e a.d profes.iona. ***“5 Ps.model of globa. hea.th educa.ion”provides.a.comprehens.ve fra.ework for the core s.udent lea.ning objectives.for globa. hea.th *** of ea.h of thes. doma.ns.is.es.entia. for prepa.ing s.udents.for mea.ingful experientia. lea.ning a.d s.illed profes.iona. pra.tice in globa. hea.th.

关键词： Educa.iona. models Globa. hea.th Profes.iona. educa.ion

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