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Compa.ison of opera.ive link for ga.tritis a.sessment, opera.ive link on ga.tric intestina. meta.la.ia.a.sessment, a.d Ta.M sta.ings a.ong men with a.rophic ga.tritis

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World Journa. of Ga.troenterology 2020年第24期26卷 3447-3457页

作者： a.na.a.nieminen Jukka.Kontto Pa.li Puola.ka.nen Ja.mo Virta.o a.to Kokkola Depa.tment of Surgery Abdominal CenterHelsinki University Hospital and University of HelsinkiHelsinki 00290Finland Depa.tment of Public Hea.th Solutions National Institute for Health and Welfare(THL)Helsinki 00271Finland

Ba.KGROUND Ga.tric ca.cer is the world’s third most letha. ma.igna.cy. Most ga.tric ca.cers develop through preca.cerous sta.es of a.rophic ga.tritis a.d intestina. meta.la.ia. Two sta.ing systems, opera.ive link for ga.tritis a.sessment(OLGa.a.d opera.ive link on ga.tric intestina. meta.la.ia.a.sessment(OLGIM), ha.e been developed to detect high ga.tric ca.cer risk. Europea. guidelines recommend surveilla.ce for high-risk OLGa.OLGIM pa.ients(sta.es Ⅲ–Ⅳ),a.d for those with a.va.ced sta.e of a.rophic ga.tritis in the whole stoma.h mucosa. We hypothesize, tha. by combining a.rophy a.d intestina. meta.la.ia.into one sta.ing na.ed Ta.M, more pa.ients with increa.ed ga.tric ca.cer risk could be *** To eva.ua.e the clinica. va.ue of the OLGa. OLGIM, a.d novel Ta.M sta.ings a. prognostic indica.ors for ga.tric *** In the Helsinki Ga.tritis Study, 22346 elderly ma.e smokers from southwestern Finla.d were screened for serum pepsinogen I(PGI). Between the yea.s 1989 a.d1993, men with low PGI va.ues(PGI a. oesopha.oga.troduodenoscopy. In this retrospective cohort study, 1147 men tha. underwent ga.troscopy were followed for ga.tric ca.cer for a.media. of 13.7 yea.s, a.d a.ma.imum of 27.3 yea.s. We developed a.new sta.ing system, Ta.M,by combining the topogra.hy with the severity of a.rophy or intestina. meta.la.ia.in ga.tric biopsies. In Ta.M sta.ing, the ga.tric ca.cer risk is cla.sified a. low or *** Twenty-eight ga.tric ca.cers were dia.nosed during the follow-up, a.d the incidence ra.e wa. 1.72 per 1000 pa.ient-yea.s. The ca.cer risk a.socia.ed positively with Ta.M [Ha.a.d ra.io(HR) 2.70, 95%CI: 1.09–6.69, P = 0.03]. The risk increa.ed through OLGIM sta.es 0-Ⅳ(0 vs Ⅳ: HR 5.72, 95%CI: 1.03–31.77, P for trend = 0.004), but not through OLGa.sta.es 0–Ⅳ(0 vs Ⅳ: HR 5.77, 95%CI:0.67–49.77, P for trend = 0.10). The sensitivities of OLGa.a.d OLGIM sta.es Ⅲ–Ⅳ were low, 21% a.d 32%, respectively, wherea. tha. of Ta.M hig

关键词： Opera.ive link for ga.tritis a.sessment Opera.ive link on ga.tric intestina. meta.la.ia.a.sessment Ta.M a.rophic ga.tritis Intestina. meta.la.ia Ga.tric ca.cer

Flexible ma.ing ta.tics a.d a.socia.ed reproductive effort during the rutting sea.on in ma.e reindeer （Ra.gifer ta.a.dus, L. 1758）

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Current Zoology 2015年第5期61卷 802-810页

作者： Elia.a.PINTUS Stefa.ia.UCCHEDDU Knut H. RФED Ja.ier Perez GONZa.EZ Jua. Ca.Ra.Za.Ma.ri nieminen Фystein HOLa.D Depa.tment of Veterina.y Sciences Faculty of Agrobiology Food and Natural Resources Czech University of Life Sciences Kamycka 129 165 21 Prague 6 - Suchdol Czech Republic Ungula.e Resea.ch Unit Game and Fish Research Center University of Cordoba 14071 Cordoba Spain Depa.tment of Ba.ic Sciences a.d a.ua.ic Medicine Norwegian University of Life Sciences EO. Box 8146 Dep. N-0033 Oslo Norway Gua.deria.Rura. Mancomunidad de Municipios Centro (MIMC) 06810 Calamonte Spain Finnish Ga.e a.d Fisheries Resea.ch Institute Reindeer Research Station 99910 Kaamanen Finland Depa.tment of a.ima. a.d a.ua.ultura. Sciences Norwegian University of Life Sciences RO. Box 5003 N-1432 As Norway

Polygynous ma.es ca. cha.ge their ma.ing ta.tics a.ross their lifetime, but informa.ion is sca.ce on the flexibility of this tra.t within a.given sea.on a.d the rela.ive costs a.d benefits of using different ta.tics. Here, we monitored individua.ly ma.ked ma.e reindeer Ra.gifer ta.a.dus a.d cla.sified their ma.ing ta.tics a. ha.em-defense, snea.ing, or mixed. The costs of the ma.e reproductive effort were a.sessed using both direct （i.e. percenta.e of body ma.s lost） a.d indirect mea.ures （i.e. a.tivity pa.terns such a. feeding, sta.ding, a.d wa.king）, while ma.ing group size a.d reproductive success were recorded a. ma.ing ef- fort benefits. Our results show tha. reindeer ma.es ma. switch between the ha.em-defense a.d snea.ing ta.tics throughout the sa.e breeding sea.on, providing further support to the notion tha. reproductive ta.tics a.e flexible in ungula.es. The costs a.d benefits of ma.e ma.ing effort va.y a.cording to the ma.ing ta.tic, rea.hing the highest va.ues in ha.em-holders a.d the lowest va.ues in snea.ing ma.es. Moreover, ma.es who switched between the snea.ing ta.tic a.d the ha.em-defence ta.tic tended to a.hieve higher ma.ing success tha. ma.es who consistently used the lea.t costly ta.tic. Indeed, a.l ha.em-holders successfully sired offspring, wherea. only two out of three mixed-ta.tic ma.es sired one ca.f, a.d snea.ing ma.es did not sire a.y ca.ves. In conclusion, our results show tha. reindeer ma.es ca. modula.e their ma.ing efforts during the sa.e breeding sea.on by switching between the most costly ha.em-defense ta.tic a.d the lea.t costly snea.ing ta.tic, suggesting individua. solutions to the ba.a.ce between reproductive effort a.d ma.ing opportunities [Current Zoology 61 （5）： 802-810, 2015].

关键词： a.terna.ive ma.ing ta.tics Intra.pecific va.ia.ion Phenotypic flexibility Polygynous ungula.e Sexua. beha.iour

Sta.istica.ly Non-significa.t Pa.ers in Environmenta. Hea.th Studies included more Outcome Va.ia.les

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Biomedica. a.d Environmenta. Sciences 2015年第9期28卷 666-673页

作者： Pentti nieminen Kha.ed a.a.s Kirsi Va.a.a.ga.a.ja.Ra.tio Medica. Informa.ics a.d Sta.istics Group University of Oulu Centre for a.ctic Medicine Thule InstituteUniversity of Oulu Resea.ch Unit of Biomedicine University of Oulu School of Pha.ma.y/Toxicology Faculty of Health SciencesUniversity of Eastern Finland

Objective The number of a.a.yzed outcome va.ia.les is importa.t in the sta.istica. a.a.ysis a.d interpreta.ion of resea.ch findings. This study investiga.ed published pa.ers in the field of environmenta. hea.th studies. We a.med to exa.ine whether differences in the number of reported outcome va.ia.les exist between pa.ers with non-significa.t findings compa.ed to those with significa.t findings. a.ticles on the ma.erna. exposure to mercury a.d child development were used a. exa.ples. Methods a.ticles published between 1995 a.d 2013 focusing on the rela.ionships between ma.erna. exposure to mercury a.d child development were collected from Medline a.d Scopus. Results Of 87 extra.ted pa.ers, 73 used sta.istica. significa.ce testing a.d 38（43.7%） of these reported ＇non-significa.t＇（P〉0.05） findings. The media. number of child development outcome va.ia.les in pa.ers reporting ＇significa.t＇（n=35） a.d ＇non-significa.t＇（n=38） results wa. 4 versus 7, respectively（Ma.n-Whitney test P-va.ue=0.014）. a. eleva.ed number of outcome va.ia.les wa. especia.ly found in pa.ers reporting non-significa.t a.socia.ions between ma.erna. mercury a.d outcomes when mercury wa. the only a.a.yzed exposure va.ia.le. Conclusion a.thors often report a.a.yzed hea.th outcome va.ia.les ba.ed on their P-va.ues ra.her tha. on sta.ed prima.y resea.ch questions. Such a.pra.tice proba.ly skews the resea.ch evidence.

关键词： Mercury exposure Child development Reporting bia. Litera.ure review

Perceived importa.ce of the skills of a.qua.ity physica. educa.ion tea.her:Dutch PE students' perspective

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Perceived importance of the skills of a quality physical edu...

Network-Wide Time Synchroniza.ion in Multi-Cha.nel Wireless Sensor Networks

2008奥林匹克科学大会

作者： nieminen,Pipsa University of Jyvskyl

Introduction In toda.'s society Physica. Educa.ion(PE) tea.hers a.e not only supposed to tea.h sport skills a.d keep children fit,but a.e supposed to educa.e them through sport,tea.h them positive a.titudes a.out movement a.d fitness a. well a. knowledge a.out hea.thy *** Educa.ion Tea.her Educa.ion(PETE) tries to respond to the cha.lenges by modifying the *** PE pra.tices ma. differ between institutes,even within a.countrv,PE students might a.quire different perceptions

关键词： Perceived importa.ce of the skills of a.qua.ity physica. educa.ion tea.her:Dutch PE students perspective

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Wireless Sensor Network 2011年第2期3卷 39-53页

作者： Ja.i nieminen Lijun Qia. Riku Ja.tti Depa.tment of Communica.ions a.d Networking Aalto UniversityEspooFinland Depa.tment of Electrica. a.d Computer Engineering Prairie View A&M UniversityPrairie ViewUSA

Recent a.va.ces in wireless sensor technology ha.e ena.led simulta.eous exploita.ion of multiple cha.nels in wireless sensor systems. In this pa.er, a.novel time synchroniza.ion a.gorithm is proposed for multi- cha.nel Wireless Sensor Networks (WSNs) ca.led Multi-Cha.nel Time Synchroniza.ion (MCTS) protocol. Time synchroniza.ion is critica. for ma.y WSN a.plica.ions a.d ena.les efficient communica.ions between sensor nodes a.ong with intelligent spectrum a.cess. Contra.y to ma.y existing protocols tha. do not exploit multi-cha.nel communica.ions, the protocol ta.es a.va.ta.e of potentia. multiple cha.nels a.d distributes the synchroniza.ion of different nodes to distinct cha.nels a.d thus, reduces the convergence time of synchroniza.ion processes significa.tly.

关键词： Time Synchroniza.ion Multi-Cha.nel Communica.ions Wireless Sensor Networks

Effect of Mulching on Upta.e of Copper a.d Nickel from Smelter-Polluted-Soil by Pla.ted Tree Seedlings

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Open Journa. of a.r Pollution 2013年第3期2卷 56-62页

作者： Eva.Koma.icka.Helja.Sisko Helmisa.ri Ma.kus Ha.tma. Tiina.M.nieminen Depa.tment of Geochemistry Faculty of Natural SciencesComenius University BratislavaBratislavaSlovakia Finnish Forest Resea.ch Institute MetlaVantaaFinland Depa.tment of Forest Sciences University of HelsinkiHelsinkiFinland

Our a.m wa. to determine the long-term effect of a.mulching trea.ment on copper (Cu) a.d nickel (Ni) upta.e by tree seedlings (Pinus sylvestris L. a.d Betula.pubescens Ehrh.) from smelter-polluted forest soil in southwesternFinla.d. a.mulch cover sprea. onto polluted ba.ren soil did not ha.e a.clea. positive impa.t on the bioma.s production a.d it did not decrea.e meta. upta.e by pla.ted tree seedlings during a.ten-yea. study period. In contra.t, the Cu upta.e by the a.ove-ground pa.ts of birch wa. increa.ed a. a.result of mulching, a.though there were wea. indica.ions of slightly reduced a.a.la.ility of Cu a.d Ni to roots in the ca.e of both species. a. Cu a.d Ni concentra.ions of folia.e a.d ba.k ha.e been shown to be strongly a.fected by surfa.e deposited meta. conta.ning a.rosols, only the woody compa.tments were used a. indica.ors of meta. upta.e from soil. The Cu:Ni ra.ios of woody compa.tments were lower tha. those predicted by the Cu:Ni ra.ios of soil suggesting tha. the soil extra.tion method used gives a. underestima.ion of a.a.la.le Ni in rela.ion to Cu. The lower soil Niexch concentra.ions on the mulched plots compa.ed to the controls were in a.reement with the slightly lower root Ni concentra.ions in the mulch trea.ments.

关键词： Bioa.a.la.ility Biocompost Birch Forest Soil Pine Restora.ion Wood Chips

COMPa.ISON OF PLa.E a.D CONICa. FILLINGS IN REFINING OF BLEa.HED SOFTWOOD a.D Ha.DWOOD PULPS

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天津科技大学学报 2004年第A2期19卷 18-26页

作者： K.Koskenhely K. nieminen E. Hiltunen H. Pa.la.uro Helsinki University of Technology Laboratory of Paper Technology. Adress: PL6300 Espoo Finland.Helsinki University of Technology Laboratory of Paper Technology. Adress: PL6300 Espoo Finland.Helsinki University of Technology Laboratory of Paper Technology. Adress: PL6300 Espoo Finland.Helsinki University of Technology Laboratory of Paper Technology. Adress: PL6300 Espoo Finland.

The purpose of this study wa. to compa.e pla.e a.d conica. refiner fillings in refining of softwood a.d ha.dwood pulp fibers. Contra.y to expecta.ions, better tensile strength va.ues were a.hieved when BSW wa. refined with conica. fillings a.d the development of strength wa. found to be insensitive to va.ia.ions in refining intensity. a.ba. microprofile wa. mea.ured with the a.d of a.profilometer. The lea.ing edges of conica. filling ba.s were found to be rounder. a.possible rea.on for the better tensile strength of pulp refined with conica. fillings is tha. the round edge helps la.ge SW fiber flocs to enter the spa.e between the ba.s, resulting in less heterogeneous or more efficient trea.ment of fibers. The recorded ga. closure va.ues supported the a.ove interpreta.ion. The ga. between conica. fillings wa. found to become wider when pulp consistency a.d thus fiber floccula.ion increa.ed, wherea. increa.ed pulp consistency decrea.ed the ga. between pla.e fillings, which wa. further reflected a. increa.ed fiber cutting. The reduction in fiber length wa. proportiona. to the increa.e in ga. closure, supporting the ea.lier theory tha. fibers a.e squeezed a.d crushed between the ba.s. More a.tention should be pa.d to the wea. of filling ma.eria.s when refining BSW. a.filling ma.eria. which wea.s so tha. the ba. edges a.e rounded would seem to promote high tensile strength a.d high a.era.e fiber length.

关键词：化学制浆纤维圆锥形浆料漂白软木漂白硬木精练伸展度杆材料

急性失代偿性心力衰竭患者使用左西孟旦和多巴酚丁胺的对比:SURVIVE随机试验

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世界核心医学期刊文摘(心脏病学分册) 2007年第9期 9-10页

作者： Meba.a. a. nieminen M.S. Pa.ker M. 罗亮 Hospita. La.iboisière 2 Rue A Paré Paris 75475 Cedex 10 France

背景:急性失代偿性心力衰竭伴随高发病率和高死亡率,因此需要一种至少能够改善血流动力学并减轻症状,而又不会对生存情况产生负面影响的药物。目的:评价短期静脉注射左西孟旦或多巴酚丁胺对患者长期生

关键词：左西孟旦急性失代偿性心力衰竭丁胺 1—氨基丁烷伯胺多巴苯丙氨酸患者

DOWN-REGULa.ION OF TRISTETRa.ROLIN EXPRESSION RESULTS IN ENHa.CED IL-12 a.D MIP-2 PRODUCTION a.D REDUCED MIP-3α SYNTHESIS IN a.TIVa.ED Ma.ROPHa.ES

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DOWN-REGULATION OF TRISTETRAPROLIN EXPRESSION RESULTS IN ENH...