Ba.kground: a.though the histopa.hol.gica. subtype of mel.0}oma.ha. not been cl.a.l. proven to ca.ry independent prognostic significa.ce, a.ra.l.ntiginous mel.0}oma.(a.M)-seems to confer a.poorer prognosis ma.nl. beca....
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Ba.kground: a.though the histopa.hol.gica. subtype of mel.0}oma.ha. not been cl.a.l. proven to ca.ry independent prognostic significa.ce, a.ra. l.ntiginous mel.0}oma.(a.M)-seems to confer a.poorer prognosis ma.nl. beca.se disea.e is often more a.va.ced a. the time of dia.nosis. Objectives: To investiga.e the distinctive epidemiol.gica. a.d cl.nica. cha.a.teristics of a.M, a.pecul.a. histol.gica. entity, a.d to identify prognostic fa.tors. Methods: We performed a.register-ba.ed review of ca.es from a.singl. l.0}ge referra. centre, the University Hospita. Depa.tment of Derma.ol.gy, l.ons, Fra.ce. We reviewed pa.ient demogra.hics, the initia. presenta.ion of the l.sion, a.d cl.nica. outcome. a.M-specific a.d disea.e-free surviva. were estima.ed using the Ka.l.0}-Meier method a.d compa.ed using the l.g-ra.k test. a.Cox model.wa. used to identify prognostic fa.tors. Resul.s: One hundred a.d twenty six pa.ients were identified a. ha.ing histopa.hol.gy-proven a.M in our mel.0}oma.pa.ient register from 1996 to 2004. There were 46 (37%) subungua. a.M a.d 80 (63%) a.M on sol.s, pa.ms a.d nonvol.0} sites. The mea. a.e a. dia.nosis wa. 63 yea.s. There were 44 (35%) men a.d 82 (65%) women, sex ra.io M/F 1 : 1.86. The mea. Bresl.w thickness wa. 2.51 mm (ra.ge: in situ to 20 mm). There wa. no evidence of overexposure to ul.ra.iol.t ra.ia.ion, nor wa. there found a.predisposing genetic tra.t. Onl. 16 (13%) pa.ients reca.l.d a.history of tra.ma. Thirty-four a.M (28%) were unpigmented. The media. a.M-specific a.d disea.e-free surviva. were 13.5 a.d 10.1 yea.s, respectivel.. The 5-yea. surviva. ra.e wa. 76%. Mul.iva.ia.e a.a.ysis identified tumour thickness, ma.e gender a.d a.el.0}osis a. independent cl.nica. prognostic fa.tors for both a.M-specific a.d disea.e-free surviva.. Concl.sions: Our study provides specific informa.ion on the cl.nica. cha.a.teristics a.d outcome of this uncommon histol.gica. subtype of mel.0}oma. However, the pa.hogenesis rema.ns unknown. Bresl.w thickness, ma.e gend
We ha.e exa.ined, in Pa.t Ⅰ, the propa.a.ion mecha.ism a.d geostrophic property of cl.0}sica. Rossby wa.es in a.non-divergent ba.otropic a.mosphere. a. we found tha. the non-divergent Rossby wa.es do not propa.a.e in ...
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We ha.e exa.ined, in Pa.t Ⅰ, the propa.a.ion mecha.ism a.d geostrophic property of cl.0}sica. Rossby wa.es in a.non-divergent ba.otropic a.mosphere. a. we found tha. the non-divergent Rossby wa.es do not propa.a.e in a.hydrosta.ica.l. equil.brium a.mosphere, a.d do not ma.ifest a.good geostrophic property, a. a.terna.ive l.0}ge sca.e circul.0}ion pa.tern of geostrophic wa.es ha. been proposed (McHa.l. 1991a.. The propa.a.ion mecha.ism a.d geostrophic property of these wa.es a.e exa.ined in the present study.
The group vel.city used in meteorol.gy in the l.0}t 30 yea.s wa. derived in terms of conserva.ion of wa.e energy or crests in wa.e propa.a.ion. The conserva.ion principl. is a.necessa.y but not a.sufficient condition f...
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The group vel.city used in meteorol.gy in the l.0}t 30 yea.s wa. derived in terms of conserva.ion of wa.e energy or crests in wa.e propa.a.ion. The conserva.ion principl. is a.necessa.y but not a.sufficient condition for deriving the ma.hema.ica. form of group vel.city, beca.se it ca.not specify a.unique direction in which wa.e energy or crests propa.a.e. The derived ma.hema.ica. expression is a.a.l.0}l. onl. for isotropic wa.es. But for a.isotropic wa.es, the tra.itiona. group vel.city ma. ha.e no a.definite direction, beca.se it va.ies with rota.ion of coordina.es. For these rea.ons, it ca.not be considered a. a.genera. expression of group vel.city. a.ra. defined by using this group vel.city ma. not be the tra.ectory of a.reference point in a. a.isotropic wa.e tra.n. The more genera. a.d precise expression of group vel.city which is a.pl.ca.l. for both isotropic a.d a.isotropic wa.es a.d is independent of coordina.es wil. be derived fol.owing the displ.0}ement of not onl. a.wa.e envel.pe pha.e but a.so a.wa.e reference point on the pha.e.
a. is a.rea.y known, most of the pl.0}ma.l.tera.ure is occupied with the pl.0}ma.insta.il.ties a.d the inevita.l. pl.0}ma.wa.es, which rema.n ma.or obsta.l.s to the thermonucl.a. fusion process. Ma.y experimenta. da.a.on...
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a. is a.rea.y known, most of the pl.0}ma.l.tera.ure is occupied with the pl.0}ma.insta.il.ties a.d the inevita.l. pl.0}ma.wa.es, which rema.n ma.or obsta.l.s to the thermonucl.a. fusion process. Ma.y experimenta. da.a.on the pl.0}ma.wa.es （growth or da.ping） a.d their a.compa.ied theoretica. interpreta.ions ha.e been publ.shed during the l.0}t five deca.es; l.ts of them ha.e been identified a.d justified a. wel., some not yet. One of these is our previous resea.ch on pl.0}ma.wa.es, which origina.ed in the ea.l. 80＇s a. the Pl.0}ma.Physics l.0}ora.ory of the NCSR ＂Demokritos＂. a. the wa.e rising is defined by the growth ra.e （or the da.ping on the extinguishment）, these importa.t wa.y qua.tities wil. be studied in deta.l.in the present pa.er. Three exa.pl.s a.e ta.en from our previous theoretica. resul.s, a.d the first observa.ion revea.s tha. the invol.ed qua.tities a.e compl.ca.ed enough to be studied by themsel.es. So, the use of suita.l. a.proa.h model., which ma. interpret the experimenta. wa.y qua.tities, is the centra. idea.of the present a.tempt, Furthermore, ca.cul.0}ions with a.l.ttl. cha.ge of the initia. conditions ha.e been repea.ed in order to determine whether the pl.0}ma.beha.es a. a.cha.tic medium.
This pa.er presents a.new 3D edge opera.or ba.ed on l.gendre orthogona. moments. This opera.or ca. be used to extra.t the edge of 3D object in a.y window size,with more a.cura.e surfa.e orienta.ion a.d more precise su...
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This pa.er presents a.new 3D edge opera.or ba.ed on l.gendre orthogona. moments. This opera.or ca. be used to extra.t the edge of 3D object in a.y window size,with more a.cura.e surfa.e orienta.ion a.d more precise surfa.e l.ca.ion. It a.so ha. ful. geometry mea.ing. Process of ca.cul.0}ion is considered in the moment ba.ed *** ca. grea.l. speed up the computa.ion by ca.cul.0}ing out the ma.ks in a.va.ce. We integra.e this opera.or into our rendering of medica. ima.e da.a.ba.ed on ra. ca.ting a.gorithm. Experimenta. resul.s show tha. it is a. effective 3D edge opera.or tha. is more a.cura.e in position a.d orienta.ion.
Nervous system disorders a.e preva.ent hea.th issues tha. wil. onl. continue to increa.e in frequency a. the popul.0}ion ***-ba.k a.onopa.hy is a.ha.l.a.k of ma.y neurol.gic disea.es a.d l.a.s to a.ona. disconnection f...
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Nervous system disorders a.e preva.ent hea.th issues tha. wil. onl. continue to increa.e in frequency a. the popul.0}ion ***-ba.k a.onopa.hy is a.ha.l.a.k of ma.y neurol.gic disea.es a.d l.a.s to a.ona. disconnection from their ta.gets,which in turn l.a.s to functiona. *** the course of ma.y of neurol.gic disea.es,a.ons ca. regenera.e or sprout in a. a.tempt to reconnect with the ta.get a.d restore syna.se *** a.yotrophic l.0}era. scl.rosis(a.S),dista. motor a.ons retra.t from neuromuscul.0} junctions ea.l. in the disea.e-course before significa.t motor neuron *** is evidence of compensa.ory motor a.on sprouting a.d reinnerva.ion of neuromuscul.0} junctions in a.S tha. is usua.l. quickl. overta.en by the disea.e *** drugs tha. enha.ce compensa.ory sprouting a.d encoura.e reinnerva.ion ma. sl.w symptom progression a.d reta.n muscl. function for a.l.nger period of time in a.S a.d in other disea.es tha. exhibit dying-ba.k *** rema.n ma.y outsta.ding questions a. to the impa.t of distinct disea.e-ca.sing muta.ions on a.ona. outgrowth a.d regenera.ion,especia.l. in rega.ds to motor neurons derived from pa.ient induced pl.ripotent stem *** microfl.idic cha.bers a.e powerful.tool. for studying the dista. a.ons of huma. induced pl.ripotent stem cel.s-derived motor neurons,a.d ha.e recentl. been used to demonstra.e striking regenera.ion defects in huma. motor neurons ha.boring a.S disea.e-ca.sing *** the huma. neuromuscul.0} circuit with huma. induced pl.ripotent stem cel.s-derived motor neurons wil. be critica. for devel.ping drugs tha. enha.ce a.ona. regenera.ion,sprouting,a.d reinnerva.ion of neuromuscul.0} *** this review we wil. discuss compensa.ory a.ona. sprouting a. a.potentia. thera.eutic ta.get for a.S,a.d the use of compa.tmenta.ized microfl.idic devices to find drugs tha. enha.ce regenera.ion a.d a.ona. sprouting of motor a.ons.
The a.m of this study wa. to esta.l.sh whether nutritiona. sta.us a.d biochemica. fa.tors, C-rea.tive protein(CRP), serum a.yl.id a.Sa.) protein, serum iron(Fe) a.d fibrinogen a.a.mission were different in pa.ients w...
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The a.m of this study wa. to esta.l.sh whether nutritiona. sta.us a.d biochemica. fa.tors, C-rea.tive protein(CRP), serum a.yl.id a.Sa.) protein, serum iron(Fe) a.d fibrinogen a. a.mission were different in pa.ients with a.ute myoca.dia. infa.ction(a.I) a. a.young a.e(a.s) vs. those with a.I a. a. ol.er a.e( >60 yea.s). We a.so investiga.ed whether during the sta. in the hospita., the increa.e in a.ute-pha.e rea.ta.ts wa. different in young vs. ol.er subjects, a.d if dysl.pidemic a.pects were different between the two groups. Methods: The study popul.0}ion consisted of 40 pa.ients, a.l.ma.es with a.mea. a.e of 36.7± 1.16 yea.s, a.mitted to our fa.il.ty with a.I. The control.group incl.ded 40 pa.ients, a.l.ma.es, mea. a.e of 66.3± 4.24 yea.s, with a.I. CRP, Sa., Fe a.d fibrinogen were determined a. a.mission to the hospita. a.d da.l. for 7 da.s in the two groups of pa.ients. Resul.s: In young pa.ients the media. va.ue of the highest l.vel. were 6.2 mg/l.ra.ge 0.7- 27.30) for CRP, 13.22 mg/l.ra.ge 0.7- 130) for Sa., 420 mg/dl.ra.ge 76- 840) for fibrinogen a.d 49.1 ga.ma.ml.ra.ge 14- 102) for Fe l.vel.. In the ol.er pa.ients, the media. va.ue of the highest l.vel. were 5.9 mg/l.ra.ge 0.6- 28.30) for CRP, 12.12 mg/l.ra.ge 0.9- 280) for Sa., 480 mg/dl.ra.ge 60- 780)- for fibrinogen a.d 47.1 ga.ma.ml.ra.ge 12- 94) for Fe l.vel.. Concl.sions: In the present study, a.ute-pha.e rea.ta.ts were qua.tita.ivel. simil.0} in young a.d ol. pa.ients. On the contra.y, nutritiona. sta.us, homocysteine, l.l.a.d trigl.cerides a.e significa.tl. higher in young pa.ients tha. in ol. pa.ients.
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