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Eye-Tra.king Ba.ed a.tism Spectrum Disorder Dia.nosis Using Cha.tic Butterfly Optimiza.ion with Deep Lea.ning Model

Computers, Ma.eria.s & Continua 2023年第8期76卷 1995-2013页

作者： Ta.ilvizhi Tha.a.a.a. Youseef a.ota.bi Surendra. Ra.endra. krishnaraj Na.a.pa. Depa.tment of Computer Science a.d Engineering Panimalar Engineering CollegeChennai600123India Depa.tment of Computer Science University College of Al JamoumUmm Al-Qura UniversityMakkah21421Saudi Arabia Depa.tment of Computer Science a.d Engineering Saveetha School of EngineeringSaveetha Institute of Medical and Technical SciencesChennai602105India School of Computing SRM Institute of Science and TechnologyKattankulathur603203India

a.tism spectrum disorder(a.D)ca. be defined a. a.neurodevelopmenta. condition or illness tha. ca. disturb kids who ha.e heterogeneous cha.a.teristics,like cha.ges in beha.ior,socia. disa.ilities,a.d difficulty communica.ing with *** tra.king(ET)ha. become a.useful method to detect *** vita. a.pect of mora. erudition is the a.titude to ha.e common visua. *** eye-tra.king a.proa.h offers va.ua.le da.a.rega.ding the visua. beha.ior of children for a.cura.e a.d ea.ly ***-tra.king da.a.ca. offer insightful informa.ion a.out the beha.ior a.d thought processes of people with a.D,but it is importa.t to be a.a.e of its limita.ions a.d to combine it with other types of da.a.a.d a.sessment techniques to increa.e the precision of a.D *** opera.es by sca.ning the pa.hs of eyes for extra.ting a.series of eye projection points on ima.es for exa.ining the beha.ior of children with *** purpose of this resea.ch is to use deep lea.ning to identify a.tistic disorders ba.ed on eye *** Cha.tic Butterfly Optimiza.ion technique is used to identify this specific ***,this study develops a. ET-ba.ed a.tism Spectrum Disorder Dia.nosis using Cha.tic Butterfly Optimiza.ion with Deep Lea.ning(ETa.D-CBODL)*** presented ETa.DCBODL technique ma.nly focuses on the recognition of a.D via.the ET a.d DL *** a.complish this,the ETa.D-CBODL technique exploits the U-Net segmenta.ion technique to recognize interested *** a.dition,the ETa.D-CBODL technique employs Inception v3 fea.ure extra.tion with CBO a.gorithm-ba.ed hyperpa.a.eter ***,the long-shorttermmemory(LSTM)model is exploited for the recognition a.d cla.sifica.ion of *** a.sess the performa.ce of the ETa.D-CBODL technique,a.series of simula.ions were performed on da.a.ets from the figure-sha.ed da.a.*** experimenta. va.ues of a.cura.y(99.29%),precision(98.78%),sensitivity(99.29%)a.d specificity(99.29%)showed a.better perfo

关键词： Eye tra.king a.D dia.nosis deep lea.ning butterfly optimiza.ion a.gorithm beha.ior a.a.ysis

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Ripoptosome:a.novel Ia.-regula.ed cell dea.h-signa.ling pla.form

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分子细胞生物学报:英文版 2011年第6期3卷 324-326页

作者： Gergely Imre Sa.it La.isch krishnaraj Ra.a.inga. Institute of Biochemistry II Goethe University School of MedicineTheodor-Stern-Kai 7D-60590 Frankfurt am MainGermany Cell Dea.h Resea.ch La.ora.ory Department of BiologyFaculty of Natural SciencesUniversity of HaifaMulti-Purpose BuildingMount CarmelHaifa 31905Israel

Recent studies ha.e revea.ed tha. cell dea.h stimuli ca. trigger progra.med necrosis,***-intera.ting serine–threonine kina.e fa.ily RIP pla.s a.crucia. role in regula.ing the switch between a.optosis a.d *** studies now describe a.novel RIP1 conta.ning∼2 MDa.Ripoptosome’complex a.sembled in the cytosol to media.e both a.optosis a.d necroptosis in response to genotoxic stress a.d TLR3 ***,cIa.s a.d XIa. function a. endogenous inhibitors of Ripoptosome by direct ubiquitina.ion of its components.

关键词： dea.h endogenous Receptor

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Clinica. considera.ions in the ma.a.ement of non-a.coholic stea.ohepa.itis cirrhosis pre- a.d post-tra.spla.t: a.multi-system cha.lenge

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World Journa. of Ga.troenterology 2020年第28期26卷 4018-4035页

作者： Justin a.Steggerda.krishnaraj Ma.endra.a. Tsuyoshi Todo Ma.en Noureddin Depa.tment of Surgery Division of TransplantationCedars-Sinai Medical CenterLos AngelesCA 90048United States Division of Digestive a.d Liver Disea.es Comprehensive Transplant CenterCedars-Sinai Medical CenterLos AngelesCA 90048United States

Non-a.coholic stea.ohepa.itis(Na.H)is the most common chronic liver disea.e worldwide,a.d the fa.test growing indica.ion for liver tra.spla.ta.ion in the United *** is now the lea.ing etiology for liver tra.spla.ta.ion in women,the second lea.ing indica.ion for men,a.d the most common ca.se a.ongst recipients a.ed 65 yea.s a.d *** with end-sta.e liver disea.e rela.ed to Na.H represent a.unique a.d cha.lenging pa.ient popula.ion due the high incidence of a.socia.ed comorbid disea.es,including obesity,type 2 dia.etes(T2D),a.d *** cha.lenges ma.ifest in the pre-liver tra.spla.ta.ion period with increa.ed wa.tlist times a.d wa.tlist ***,these pa.ients ca.ry considera.le risk of morbidity a.d morta.ity both before a.ter liver tra.spla.ta.ion,with high ra.es of T2D,ca.diova.cula. disea.e,chronic kidney disea.e,poor nutrition,a.d disea.e *** tra.spla.ta.ion for these pa.ients requires identifica.ion a.d ma.a.ement of their comorbidities in the fa.e of liver *** eva.ua.ions include a.thorough pre-tra.spla.t workup with a.complete ca.dia. eva.ua.ion,control of dia.etes,nutritiona. support,a.d even,potentia.ly,consulta.ion with a.ba.ia.ric *** a.ticle provides a.comprehensive review of the conditions a.d cha.lenges fa.ing pa.ients with Na.H cirrhosis undergoing liver tra.spla.ta.ion a.d provides recommenda.ions for eva.ua.ion a.d ma.a.ement to optimize them before liver tra.spla.ta.ion to produce successful outcomes.

关键词： Liver tra.spla.ta.ion Non-a.coholic fa.ty liver disea.e Obesity Meta.olic syndrome

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Groundwa.er Potentia. Zoning in Thiruma.imutta. Sub-Ba.in Ta.ilna.u, India.a.GIS a.d Remote Sensing a.proa.h

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Geo-Spa.ia. Informa.ion Science 2011年第1期14卷 17-26页

作者： MURUGESa. Va.a.tha.iga. krishnaraj Sriniva.a.oorthy Ka.NUSa.Y Vija.a.a.a.a. SELVa.a. Gopina.h SUBRa.a.Ya.Sa.ma Depa.tment of Ea.th Sciences Annamalai UniversityAnnamalai Nagar-608 002Tamil NaduIndia Na.iona. Geophysica. Resea.ch Institute(NGRI) Uppal RoadHyderabad-500 007India

The ma.n objective of the study is to identify groundwa.er potentia. zones in Thiruma.imutta. ba.in with a. integra.ed a.proa.h using Remote Sensing a.d geogra.hica. informa.ion system(GIS).FCC Ima.e of La.dsa. TM 30 m resolution da.a.a.d topogra.hic ma.s ha. been used to genera.e thema.ic ma.s like geology,geomorphology,linea.ent a.d linea.ent density,dra.n-a.e,dra.na.e density,a.d slope ma. of the study a.ea.a.number of geomorphic units such a. Denuda.iona. hills,structura. hills,Ba.a.a.,Colluvia. pla.n,Pedipla.n,Deep Pediment a.d a.luvia. pla.ns ha.e been observed.a.composite groundwa.er potentia. ma. ha. been genera.ed a. very high,high,medium,low a.d very low ba.ed on the groundwa.er a.a.la.ility *** upper,mid-dle a.d downstrea. of the ba.ins ha.e been identified a. potentia. zones for groundwa.er *** regions of linea.ents a.d intersecting linea.ents proved for groundwa.er potentia. *** da.a.genera.ed wa. va.ida.ed with field checks a.d ob-served to be in conformity with the sa.e.

关键词：地形学地下水 La.dsa. 潜在的地区遥感 GIS

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与单能CT血管成像比较,单源双能CT腹部血管成像的初步经验:影像质量、增强效果、诊断及辐射剂量

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国际医学放射学杂志 2013年第2期 194-194页

作者： D.F. Pinho N.M. Kulka.ni a. krishnaraj S.P. Ka.va.D.V. Sa.a.i 赵芳 Division of a.domina. Ima.ing a.d Intervention Mas- sachusetts General Hospital 55 Fruit StreetWhite270BostonMA 02114 USA

目的与单能CT(SE-CT)比较,评价虚拟单能谱成像(VMS)的影像质量及对腹主动脉疾病密度成像的可行性。方法回顾性研究35例病人(男32例,平均年龄76.5岁)主髂动脉系统的单源双能CT(ssDECT)与SE-CT的对比。对ssDECT数据进行后处理以产生不同能... 详细信息

目的与单能CT(SE-CT)比较,评价虚拟单能谱成像(VMS)的影像质量及对腹主动脉疾病密度成像的可行性。方法回顾性研究35例病人(男32例,平均年龄76.5岁)主髂动脉系统的单源双能CT(ssDECT)与SE-CT的对比。对ssDECT数据进行后处理以产生不同能谱VMS及水密度(WD)影像。采用5分制评估影像质量参数。记录主髂动脉密度衰减及对比噪声比(CNR)。对比WD与真正的非强化(TNE)影像。记录辐射剂量并进行统计学分析。结果 70keV时的影像质量更高(P<0.01),50keV时的肾动脉分支显示更清楚(P<0.005)。50、70keV时的密度衰减和CNR均较高(P<0.0001)。WD成像具有可诊断的影像质量,但噪声比TNE影像高(P<0.0001)。单期ssDECT的辐射剂量比双期SE-CT低(P<0.0001)。结论与SE-CT的120kV影像相比,ssDECT的70keV影像具有更高的对比增强效果,并能改善主髂动脉CT影像质量。WD影像在潜在降低剂量方面可以作为TNE影像的有效代替。要点①多层CT血管成像目前是一种常规检查。②ssDECT可同时产生不同的管电压。③70keV时影像比传统SE-CT影像质量更高。④70keV时影像比SE-CT影像噪声更少。

关键词：双能CT CT血管成像多层CT 辐射剂量虚拟平扫图像

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Pa.dy Lea. Disea.e Detection Using a. Optimized Deep Neura. Network

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Computers, Ma.eria.s & Continua 2021年第7期68卷 1117-1128页

作者： Sha.ka.a.a.a.a.a. Na.ini Na.a.pa. krishnaraj Tha.ga.ya. Ja.a.a.ka. Ka.imuthu Vinothkuma. a.tony Sa.a. Fra.cis Britto Ka.a.ra. Subra.a.ia. Chokka.iga. Bha.a.ira.a Depa.tment of Computer Science&Engineering University College of EngineeringBIT CampusAnna UniversityTiruchirappalli620024India School of Computing SRM Institute of Science and TechnologyKattankulathur603203India Depa.tment of Electronics a.d Communica.ion Engineering University College of EngineeringBIT CampusAnna UniversityTiruchirappalli620024India Depa.tment of Electronics&Communica.ion Engineering SSM Institute of Engineering and TechnologyDindigul624002India Depa.tment of Mecha.ica. Engineering Rohini College of Engineering and TechnologyPalkulam629401India Depa.tment of ECE Karpagam Academy of Higher EducationCoimbatore641021India Depa.tment of Electrica. a.d Electronics Engineering SRM Institute of Science and TechnologyChennai603203India

Precision a.riculture is a.concept of fa.m ma.a.ement which ma.es use of IoT a.d networking concepts to improve the *** disea.es a.e one of the underlying ca.ses in the decrea.e in the number of qua.tity a.d qua.ity of the fa.ming *** of disea.es from the pla.t ima.es is a. a.tive resea.ch topic which ma.es use of ma.hine lea.ning(ML)a.proa.hes.a.novel deep neura. network(DNN)cla.sifica.ion model is proposed for the identifica.ion of pa.dy lea. disea.e using pla.t ima.e *** errors were minimized by optimizing weights a.d bia.es in the DNN model using a.crow sea.ch a.gorithm(CSa.during both the sta.da.d pre-tra.ning a.d fine-tuning *** DNN-CSa.a.chitecture ena.les the use of simplistic sta.istica. lea.ning techniques with a.decrea.ed computa.iona. workloa.,ensuring high cla.sifica.ion *** lea. ima.es were first preprocessed,a.d the a.ea. indica.ive of disea.e were initia.ly extra.ted using a.k-mea.s clustering *** wa. then a.plied to elimina.e regions not indica.ive of ***,a.set of fea.ures were extra.ted from the previously isola.ed disea.ed ***,the cla.sifica.ion a.cura.y a.d efficiency of the proposed DNN-CSa.model were verified experimenta.ly a.d shown to be superior to a.support vector ma.hine with multiple cross-fold va.ida.ions.

关键词： Lea. cla.sifica.ion pa.dy lea. deep lea.ning meta.euristics optimiza.ion crow sea.ch a.gorithm

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miRNa.24 a.d miRNa.466i-5p controls infla.ma.ion in ra. hepa.ocytes

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Cellula. & Molecula. Immunology 2015年第1期12卷 113-115页

作者： Subra.a.ia. Sa.a.a.a. krishnaraj Thirugna.a.a.ba.tha. Ha.za.Ha.ieh Kula.da.velu Ka.ika.a. Dura.ra. Seka. Rukkuma.i Ra.a.opa.a. Villia.ur Ibra.im Ha.rul Isla. Division of Ethnopha.ma.ology Entomology Research Institute Loyola College Chennai India Pondicherry Centre for Biologica. Sciences Pondicherry India Sta.e Bio-centrol La.ora.ory Perunthalaivar Kamaraj Krishi Vigyan Kendra (PKKVK) Kurumbapet Puducherry India Depa.tment of Biologica. Sciences Faculty of Science King Faisal University AI Hassa Saudi Arabia School of Bioscience a.d Technology Vellore Institute of Technology VIT University Vellore India Depa.tment of Biochemistry a.d Molecula. Biology Pondicherry University Pondicherry India

The discovery of microRNa. （miRNa.） is one of tbe most significa.t brea.throughs in recent deca.es, miRNa. a.e a.cla.s of sma.l, endogenous, non-coding RNa. （19-24 nt） tha. nega.ively regula.e the expression of ta.get genes by binding to their 3＇ untra.sla.ed region a.d a.e involved in va.ious biologica. processes. Three ma.n a.proa.hes tha. a.e globa.ly used for the detection of miRNa.include direct cloning, forwa.d genetics a.d computa.iona. a.proa.hes using bioinforma.ics.

关键词： miRNa.24 miRNa.466i-5p controls

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Deep lea.ning ba.ed detection of monkeypox virus using skin lesion ima.es

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Medicine in Novel Technology a.d Devices 2023年第2期18卷 234-246页

作者： Tusha. Na.a. krishnaraj Cha.a.a.Nira.ja.a.Sa.pa.hila.Hilda.Ma.rose Nitila.Gokulkrishna. Mura.idha. Ba.ry G Srika.th Pra.hu Swa.hi K.S Sha.hikira. Uma.a.th Depa.tment of Biomedica. Engineering Manipal Institute of TechnologyManipal Academy of Higher EducationManipalKarnataka576104India Depa.tment of Computer Science a.d Engineering Manipal Institute of TechnologyManipal Academy of Higher EducationManipalKarnataka576104India Pra.a.na.School of Public Hea.th Manipal Academy of Higher EducationManipalKarnataka576104India Depa.tment of Medicine Dr.T.M.A.Pai HospitalManipal Academy of Higher EducationUdupiKarnataka576101India

a. we set into the second ha.f of 2022,the world is still recovering from the two-yea. COVID-19 ***,over the pa.t three months,the outbrea. of the Monkeypox Virus(MPV)ha. led to fifty-two thousa.d confirmed ca.es a.d over one hundred *** ca.sed the World Hea.th Orga.isa.ion to decla.e the outbrea. a.Public Hea.th Emergency of Interna.iona. Concern(PHEIC).If this outbrea. worsens,we could be looking a. the Monkeypox virus ca.sing the next globa. *** Monkeypox a.fects the huma. skin,the symptoms ca. be ca.tured with regula. *** sa.ples of these ima.es ca. be used a. a.tra.ning da.a.et for ma.hine lea.ning-ba.ed detection *** a.regula. ca.era.to ca.ture the skin ima.e of the infected person a.d running it a.a.nst computer vision models is *** this resea.ch,we use deep lea.ning to dia.nose monkeypox from skin lesion *** a.publicly a.a.la.le da.a.et,we tested the da.a.et on five pre-tra.ned deep neura. networks:GoogLeNet,Pla.es365-GoogLeNet,SqueezeNet,a.exNet a.d *** wa. done to choose the best *** metrics such a. a.cura.y,precision,reca.l,f1-score a.d a.C were *** the a.ove models,ResNet18 wa. a.le to obta.n the highest a.cura.y of 99.49%.The modified models obta.ned va.ida.ion a.cura.ies a.ove 95%.The results prove tha. deep lea.ning models such a. the proposed model ba.ed on ResNet-18 ca. be deployed a.d ca. be crucia. in ba.tling the monkeypox *** the used networks a.e optimized for efficiency,they ca. be used on performa.ce limited devices such a. sma.tphones with *** a.dition of expla.na.le a.tificia. intelligence techniques LIME a.d Gra.Ca. ena.les visua. interpreta.ion of the prediction ma.e,helping hea.th professiona.s using the model.

关键词： Deep lea.ning Disea.e dia.nosis Ima.e processing Monkeypox virus Ma.hine lea.ning Tra.sfer lea.ning

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Predicting Virologica. Fa.lure with Immunologica. Criteria.in First Line a.T Pa.ients in a.Resource Poor Setting

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World Journa. of a.DS 2014年第4期4卷 413-421页

作者： krishnaraj Ra.a.Chocka.inga. Cha.dra.eka. O. R. krishnaraja.ekha. Na.a.a.a. Ra.icha.dra. Sa.a.opa. Kuma. Gurusa.y Ma.oha.a. Iruda.a.a. a.a.a.Sha.mila Government Hospita. of Thora.ic Medicine (GHTM) Tambaram Sanatorium Chennai India Consulta.t Karpagam Faculty of Medical Sciences and Research and I-TECH Coimbatore India

Indroduction: Na.iona. a.ds control Orga.isa.ion in India.implementing Na.iona. a.DS control?progra. uses WHO’s immunologica. criteria.to screen virologica. fa.lure. Using immunologica. criteria.to detect virologica. fa.lure ha. to be a.sessed. Predicting virologica. fa.lure with immunologica. criteria.in resource limited settings ha. low sensitivity. Fa.tors tha. influence the outcome a.e studied. Methods: Retrospective study in tertia.y ca.e centre for HIV a.d TB, Chenna., India. Out of 35,044 on a.T between Ja.ua.y 2008 a.d September 2009, 452 suspected immunologica. fa.lures were referred. 273 screened for virologica. fa.lure.?Frequency, sensitivity/specificity, positive/nega.ive predictive va.ues, chi-squa.e test, odds-ra.io, independent sa.ple t test for vira. loa. grea.er tha. 10,000 a.d 1000 of ea.h immunologica. criterion using Epi-Info a.d SPSS version 19. Results: 172 ha. virologica. fa.lure (62.09%). a.era.e a.e of fa.led wa. 37.33. Single criteria.s sensitivity wa. 60 to 84 for detecting virolologica. fa.lure. Two or more criteria.ha. specificity 55 to 79. Combina.ion of two or more criteria.increa.ed odds ra.io for virologica. fa.lure. Positive predictive va.ue wa. a.ove 63 for a.l criteria. PPV wa. a.ove 80 to the criterion a.l three positive. Conclusions: a.T na.ve pa.ients with >95% a.herence the sensitivity of immunologica. criteria.to detect virologica. fa.lure is three times tha. ea.lier studies. Combina.ion of criteria.is more significa.tly a.socia.ed with virologica. fa.lure. Odds ra.io doubled for two or more combina.ion of criteria. Immunologica. criteria.is a.forda.le/a.cepta.le for screening virologica. fa.lure, with a.herence > 95% a.d longer the dura.ion of a.T.

关键词： a.T Immunologica. Fa.lure Virologica. Fa.lue Immunologica. Criteria Resource Limited Settings

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a.rtic Dissection a.ter Percuta.eous Corona.y Intervention for a.ute Corona.y Syndrome: a. Outcomes-Ba.ed Study from the Na.ionwide Inpa.ient Sa.ple Da.a.a.e

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Interna.iona. Journa. of Clinica. Medicine 2017年第1期8卷 21-33页

作者： Christine S. M. La. Georgia.J. McRoy krishnaraj Ma.endra.a. Keda. P. Kulka.ni Rona.d S. Cha.berla.n Depa.tment of Surgery Saint Barnabas Medical Center Livingston NJ USA School of Medicine Saint George’s University St. George Grenada Depa.tment of Surgery New Jersey Medical School Rutgers University Newark NJ USA Depa.tment of Surgery Banner MD Anderson Cancer Center Gilbert AZ USA

Introduction: a.rtic dissection is a.ra.e complica.ion of Percuta.eous Corona.y Intervention (PCI) for a.ute Corona.y Syndrome (a.S), but is a.socia.ed with morta.ity ra.es of up to 20%. This study a.sessed the demogra.hic a.d clinica. profile of a.la.ge cohort of pa.ients undergoing PCI for a.S to a.sess pa.ient a.d clinica. risk fa.tors tha. ma. predispose to the development of a.rtic dissection. Methods: The Na.ionwide Inpa.ient Sa.ple (NIS) da.a.a.e (2001-2011) wa. used to a.stra.t a.mission da.a.on pa.ients undergoing PCI for a.S. Results: 777,595 pa.ients underwent PCI a.d 380 (0.05%) developed a.rtic dissection. Pa.ients who developed a.rtic dissection were more often older (68 vs. 64 yea.s), fema.e (47.4% vs. 33.8%), insured through Medica.e (56.2% vs. 50.7%), Medica.d (7.9% vs. 5.3%) or uninsured/self-pa. (6.3% vs. 4.7%), p p Conclusion: a.rtic dissection is a.ra.e complica.ion of PCI, which occurs more often in older pa.ients with Medica.e insura.ce sta.us. Hispa.ics, fema.es, uninsured pa.ients a.d those with PVD a.e a. the highest risk of a.rtic dissection. Clinicia.s should be more cogniza.t of pa.ients a. increa.ed risk of developing PCI in order to institute ea.lier screening in high-risk pa.ients.

关键词： a.rtic Dissection Percuta.eous Corona.y Intervention NIS

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