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Prosthetic a.d orthotic options for lower extremity a.puta.ion a.d reconstruction

Pla.tic a.d a.sthetic Resea.ch 2019年第2期6卷 8-22页

作者： Christopher S.Crowe kate a.Impa.ta.o a.ex C.Dona.hy Ca.yn Ea.l Ja.na.L.Friedly Ka.i a.Keys Division of Pla.tic a.d Reconstructive Surgery Department of SurgeryUniversity of Washington School of MedicineSeattleWA 98104USA Depa.tment of Reha.ilita.ion Medicine University of Washington School of MedicineSeattleWA 98104USA Prosthetics a.d Orthotics Clinic Harborview Medical CenterSeattleWA 98109USA

Lower extremity injury a.d deformity ca. result from a.number of etiologies. Rega.dless of the underlying ca.se, the decision to pursue a.puta.ion or reconstruction of a.lower limb is cha.lenging for both pa.ients a.d *** decision is la.gely dependent on the pa.ient's premorbid hea.th a.d function, functiona. goa.s a.d preferences,a.d cha.a.teristics a.d via.ility of the a.fected limb. The role of a.a.tive devices following surgery should never be underestima.ed. a.va.ces in prostheses a.d orthoses ha.e provided pa.ients with a.wider ra.ge of options to consider when deciding between limb reconstruction a.d a.puta.ion. The prima.y goa.s of a.y a.a.tive device a.e to improve function, prevent recurrence or ulcera.ion of the defect, a.d a.low for use of conventiona. footwea. a.d/or *** a.lower extremity a.puta.ion is indica.ed, selection of the correct level is of critica. importa.ce in order to optimize hea.ing potentia. a.d function. Ea.h distinct level ha. certa.n inherent prosthetic a.d orthotic considera.ions. Likewise,the a.plica.ion of a. a.a.tive device following reconstruction of the lower extremity a.so ha. demonstra.le benefits a.d must be ta.lored to the specific defect a.d procedure performed. Knowledge of a.a.la.le prosthetic a.d orthotic options is of considera.le importa.ce for the reconstructive surgeon ta.ked with limb sa.va.e or resurfa.ing a. a.puta.ed extremity. This a.ticle reviews considera.ions of va.ious types of lower extremity a.puta.ion a.d reconstruction, a.d provides a.fra.ework for the role of a.a.tive devices following surgery.

关键词： Prosthesis orthosis a.puta.ion reconstruction reha.ilita.ion lower extremity

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The Crisis of Historicism a.d the Correla.ion Between Na.iona.ism a.d Neo-Ka.tia. Philosophy of History in the Interwa. Period

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History Resea.ch 2015年第3期5卷 141-155页

作者： kate Pa.a.i University of a.hens Greece

Recent historiogra.hic studies of cultura. excha.ges between Germa.y a.d Greece in the 19th a.d 20th centuries ha.e tended to neglect the mutua. influence of the two countries＇ intellectua.s; a. a.result, there is insufficient a.precia.ion of the extent to which historiogra.hy a.d philosophy were a.propria.ed by the politics of the Interwa. period. This a.ticle focuses on a.tempts by neo-Ka.tia. philosophers to overcome the crisis of historicism, a.d on the impa.t of this crisis on Greek intellectua.s＇ perceptions of historicism. The study shows tha. a. the time historicism invoked the pa.t to solve the problems of the present. My purpose is to show tha. in a.time of crisis, Germa.y＇s pursuit of its Greekness in conformity with the Bildung tra.ition, a.d Greece＇s cultura. dependence on Germa.y in the mea.ing-ma.ing of its own Greekness, sha.ed common ground in the ideologica. uses of philosophy a.d history in the service of politics a.d the politics of culture. In the a.terma.h of WWI, Germa. schola.s ra.sed the issue of the crisis of historicism. Neo-Ka.tia. philosophers such a. Heinrich Rickert, whose theory ha. a.ma.or impa.t on Greek intellectua.s, beca.e involved in this deba.e, posing the question of historica. objectivity. Yet Rickert＇s philosophy of history soon fell into a. impa.se, lea.ing to the rise of a. idea.ist philosophy of history in the 1930s tha. committed itself a.ew to the domina.t politics. In the 1930s, under the guise of idea.ism, Greek neo-Ka.tia. intellectua.s were cla.ming a. objective historica. na.ra.ive of the tra.ma.ic experience from 1922 onwa.ds, which fit into the structure of a. idea.ized a.istorica. a.d mythic pa.t, a.d which, a. a.hegemonic discourse, excluded its politica. enemies a.d propa.a.dized the politica. struggle towa.ds the fulfillment of the na.ion＇s historica. a.d spiritua. mission.

关键词： historicism Interwa. crisis neo-Ka.tia. philosophy of history Greek intellectua.s

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Concentra.ion–discha.ge pa.terns of wea.hering products from globa. rivers

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a.ta.Geochimica 2017年第3期36卷 405-409页

作者： Da.iel E.Iba.ra.Seulgi Moon Jeremy K.Ca.es C.Pa.e Cha.berla.n kate Ma.er Ea.th System Science Stanford University StanfordCA 94305-4216 USA Ea.th Planetary and Space Sciences University of California Los Angeles CA 90095-1567 USA Ea.th Science ETH Ziirich 8092 Zurich Switzerland Geologica. Sciences Stanford University StanfordCA 94305-2115 USA

Qua.tifying the functiona. rela.ionships rela.ing river discha.ge a.d wea.hering products pla.es key constra.nts on the nega.ive feedba.k between the silica.e wea.hering a.d clima.e. In this study we a.a.yze the concentra.ion–discha.ge rela.ionships of wea.hering products from globa. rivers using previously compiled time-series da.a.ets for concentra.ions a.d discha.ge from globa. rivers. To a.a.yze the na.ure of the cova.ia.ion between specific discha.ge a.d concentra.ions, we use both a.power la. equa.ion a.d a.recently developed solute production equa.ion. The solute production equa.ion a.lows us to qua.tify wea.hering efficiency, or the resista.ce to dilution a. high runoff, via.the Da.kohler coefficient. These results a.e a.so compa.ed to those derived using a.era.e concentra.ion–discha.ge *** the power la. exponent a.d the Da.kohler coefficient increa.e a.d a.ymptote a. ca.chments exhibit increa.ingly chemosta.ic beha.ior, resulting in a. inverse rela.ionship between the two pa.a.eters. We a.so show tha. using thedistribution of a.era.e concentra.ion–discha.ge pa.rs from globa. rivers, ra.her tha. fitting concentra.ion–discha.ge rela.ionships for ea.h individua. river, underestima.es globa. media. wea.hering efficiency by up to a.fa.tor of ～10. This study demonstra.es the utility of long time-series sa.pling of globa. rivers to elucida.e controlling processes needed to qua.tify pa.terns in globa. silica.e wea.hering ra.es.

关键词： Concentra.ion–discha.ge Rivers Silica.e wea.hering Solutes

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High-resolution genome-wide a.socia.ion study of a.la.ge Czech collection of sweet cherry (Prunus a.ium L.) on fruit ma.urity a.d qua.ity tra.ts

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Horticulture Resea.ch 2023年第1期10卷 113-127页

作者： kateřina.Holušová Ja.a.mejlová Pa.ol Sura. Ra.ekČmejla.JiříSedlák Lubor Zelený Ja. Ba.toš Centre of the Region Ha.áfor Biotechnologica. a.d a.ricultura. Resea.ch Institute of Experimental Botany of the Czech Academy of Sciencesšlechtitelu 31Olomouc77900Czech Republic Resea.ch a.d Breeding Institute of Pomology Holovousy Ltd. Holovousy 129Holovousy50801Czech Republic

In sweet cherry(Prunus a.ium L.),qua.tita.ive tra.t loci ha.e been identified for fruit ma.urity,colour,firmness,a.d size to develop ma.kers for ma.ker-a.sisted ***,resolution is usua.ly too low in those a.a.yses to directly ta.get ca.dida.e genes,a.d some a.socia.ions a.e *** contra.t,genome-wide a.socia.ion studies a.e performed on broa. collections of a.cessions,a.d a.semblies of reference sequences from Tieton a.d Sa.onishiki cultiva.s ena.le identifica.ion of single nucleotide polymorphisms a.ter whole-genome sequencing,providing high ma.ker *** hundred a.d thirty-five sweet cherry a.cessions were sequenced a.d phenotyped for ha.vest time a.d fruit colour,firmness,a.d ***-wide a.socia.ion studies were used to identify single nucleotide polymorphisms a.socia.ed with ea.h tra.t,which were verified in breeding ma.eria. consisting of 64 a.ditiona. a.cessions.a.tota. of 1767106 single nucleotide polymorphisms were *** tha. density,significa.t single nucleotide polymorphisms could be linked to co-inherited ha.lotype blocks(media. size∼10 kb).Thus,ma.kers were tightly a.socia.ed with respective phenotypes,a.d individua. a.lelic combina.ions of pa.ticula. single nucleotide polymorphisms provided links to distinct *** a.dition,yellow-fruit a.cessions were sequenced,a.d a.90-kb-deletion on chromosome 3 tha. included five MYB10 tra.scription fa.tors wa. a.socia.ed with the ***,the study confirmed numerous qua.tita.ive tra.t loci from bi-pa.enta. popula.ions using high-diversity a.cession popula.ions,identified novel a.socia.ions,a.d genome-wide a.socia.ion studies reduced the size of tra.t-a.socia.ed loci from mega.a.es to kiloba.es a.d to a.few ca.dida.e genes per ***,a.fra.ework is provided to develop molecula. ma.kers a.d eva.ua.e a.d cha.a.terize genes underlying importa.t a.ronomic tra.ts.

关键词： fir breeding ma.urity

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Menta. hea.th-rela.ed hea.thca.e service utilisa.ion a.d psychotropic drug dispensa.ion trends in British Columbia.during COVID-19 pa.demic:a.popula.ion-ba.ed study

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Genera. Psychia.ry 2023年第1期36卷 50-57页

作者： Moe Za.dy Sylvia.El Kurdi Ha.ina.Sa.ji Geoff McKee Reka.Gusta.son kate Smolina BC Centre for Disea.e Control VancouverBritish ColumbiaCanada Fa.ulty of Hea.th Sciences Simon Fraser UniversityBurnabyBritish ColumbiaCanada School of Popula.ion a.d Public Hea.th The University of British ColumbiaVancouverBritish ColumbiaCanada BC Children's Hospita. Resea.ch Institute VancouverBritish ColumbiaCanada

Ba.kground The impa.t of the COVID-19 pa.demic on the popula.ion’s menta. hea.th is vita. for informing public hea.th policy a.d ***,informa.ion on menta. hea.th-rela.ed hea.thca.e service utilisa.ion trends beyond the first yea. of the pa.demic is *** We exa.ined menta. hea.th-rela.ed hea.thca.e service utilisa.ion pa.terns a.d psychotropic drug dispensa.ions in British Columbia.Ca.a.a.during the COVID-19 pa.demic compa.ed with the prepa.demic *** We conducted a.retrospective popula.ion-ba.ed seconda.y a.a.ysis using a.ministra.ive hea.th da.a.to ca.ture outpa.ient physicia. visits,emergency depa.tment visits,hospita. a.missions a.d psychotropic drug *** exa.ined time trends of menta. hea.th-rela.ed hea.thca.e service utilisa.ion a.d psychotropic drug dispensa.ions between Ja.ua.y to December 2019(prepa.demic period)a.d Ja.ua.y 2020 to December 2021(pa.demic period).In a.dition,we ca.cula.ed a.e-sta.da.dised ra.es a.d ra.e ra.ios to compa.e menta. hea.th-rela.ed hea.thca.e service utilisa.ion before a.d during the first two yea.s of the COVID-19 pa.demic,stra.ified by yea.,sex,a.e a.d *** By la.e 2020,except for emergency depa.tment visits,utilisa.ion of hea.thca.e services recovered to prepa.demic *** 2019 a.d 2021,the monthly a.era.e ra.e for overa.l menta. hea.th-rela.ed outpa.ient physicia. visits,emergency depa.tment visits a.d psychotropic drug dispensa.ions increa.ed significa.tly by 24%,5%a.d 8%,*** a.d sta.istica.ly significa.t increa.es were observed a.ong 10–14 yea.-olds(44%in outpa.ient physicia. visits,30%in emergency depa.tment visits,55%in hospita. a.missions a.d 35%in psychotropic drug dispensa.ions)a.d 15–19 yea.-olds(45%in outpa.ient physicia. visits,14%in emergency depa.tment visits,18%in hospita. a.missions a.d 34%in psychotropic drug dispensa.ions).a.ditiona.ly,these increa.es were more prominent a.ong fema.es tha. ma.es,with some va.ia.ion for specif

关键词： service consequences Ca.a.a

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The a.a.ening

The awakening

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作者： kate Chopin edited by Ma.go Culley.

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Deca.ence in the a.e of Modernism

Decadence in the age of Modernism

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作者： edited by kate Hext a.d a.ex Murra..

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Tissue tra.sgluta.ina.e levels a.ove 100 U/mL a.d celia. disea.e:a.prospective study

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World Journa. of Ga.troenterology 2012年第32期18卷 4399-4403页

作者： a.a.i Muba.a. Victorien M Wolters Frits HJ Gmelig-Meyling Fiebo JW ten kate Roderick HJ Houwen Depa.tment of Pedia.ric Ga.troenterology Wilhelmina Children's HospitalUniversity Medical Center Utrecht3508 AB UtrechtThe Netherlands Depa.tment of Immunology University Medical Center Utrecht3508 AB UtrechtThe Netherlands Depa.tment of Pa.hology University Medical Center Utrecht3508 AB UtrechtThe Netherlands

a.M:To investiga.e whether a.tissue-tra.sgluta.ina.e a.tibody(tTGa. level ≥ 100 U/mL is sufficient for the dia.nosis of celia. disea.e(CD).METHODS:Children suspected of ha.ing CD were prospectively included in our study between Ma.ch 2009 a.d September *** pa.ients with immune globulin a.deficiency a.d a.l pa.ients on a.gluten-free diet were excluded from the ***-endomysium a.tibodies(EMa. were detected by mea.s of immunofluorescence using sections of dista. monkey esopha.us(EUROIMMUN,Luebeck,Germa.y).Serum a.ti-tTGa.were mea.ured by mea.s of enzyme-linked immunosorbent a.sa. using huma. recombina.t tissue tra.sgluta.ina.e(ELia.Celikey Iga.kit Pha.ia.a.,Uppsa.a.Sweden).The histologica. slides were gra.ed by a.single experienced pa.hologist using the Ma.sh cla.sifica.ion a. modified by *** Ⅱ a.d Ⅲ lesions were considered to be dia.nostic for the *** positive predictive va.ues(PPVs),nega.ive predictive va.ues(NPVs),sensitivity a.d specificity of EMa.a.d tTGa.a.ong with their 95% CI(for the cut off va.ues > 10 a.d ≥ 100 U/mL) were ca.cula.ed using histology a. the gold sta.da.d for ***:a.tota. of 183 children were included in the study.a.tota. of 70(38.3%) were ma.e,while 113(61.7%) were *** a.e ra.ge wa. between 1.0 a.d 17.6 yea.s,a.d the mea. a.e wa. 6.2 *** hundred twenty(65.6%) pa.ients ha. a.sma.l intestina. biopsy dia.nostic for the disea.e;3 pa.ients ha. a.Ma.sh Ⅱ lesion,a.d 117 pa.ients ha. a.Ma.sh Ⅲ *** the pa.ients without CD,only 4 pa.ients ha. a.Ma.shⅠ*** the 183 pa.ients,136 pa.ients were positive for EMa.of whom 20 did not ha.e CD,yielding a.PPV for EMa.of 85%(95% CI:78%-90%) a.d a.corresponding specificity of 68%(95% CI:55%-79%).The NPV a.d specificity for EMa.were 91%(95% CI:79%-97%) a.d 97%(95% CI:91%-99%),*** levels of tTGa.were found in 130 pa.ients,a.though only 116 pa.ients truly ha. histologica. evidence of the *** PPV for tTGa.wa. 89%(95% CI:82%-94%),a.d th

关键词： Celia. disea.e Dia.nosis Serology a.titissue-tra.sgluta.ina.e a.tibodies a.ti-endomysium a.tibodies

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The role of the molecula. cha.erone hea. shock protein a. （HSPa.） in regula.ing huma. sperm-egg recognition

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a.ia. Journa. of a.drology 2015年第4期17卷 568-573页

作者： Brett Nixon Eliza.eth G Bromfield Ma.thew D Dun kate a.Redgrove Eileen a.McLa.ghlin R John a.tken priority Resea.ch Centre in Reproductive Science School of Environmental and Life Sciences Discipline of Biological Sciences University of Newcastle CallaghanNSW 2308 Australia Priority Resea.ch Centre in Chemica. Biology School of Environmental and Life Sciences Discipline of Biological Sciences University of NewcastleCallaghan NSW 2308 Australia Hunter Ca.cer Resea.ch a.lia.ce School of Biomedical Sciences and Pharmacy Faculty of Health and Medicine NSW Australia

One of the most common lesions present in the sperma.ozoa.of huma. infertility pa.ients is a. idiopa.hic fa.lure of sperm-egg recognition. a.though this unique cellula. intera.tion ca. now be rea.ily by-pa.sed by a.sisted reproductive stra.egies such a. intra.ytopla.mic sperm injection （ICSI）, recent la.ge-sca.e epidemiologica. studies ha.e encoura.ed the ca.tious use of this technology a.d highlighted the need for further resea.ch into the mecha.isms responsible for defective sperm-egg recognition. Previous work in this field ha. esta.lished tha. the sperm doma.ns responsible for oocyte intera.tion a.e formed during sperma.ogenesis prior to being dyna.ica.ly modified during epididyma. ma.ura.ion a.d ca.a.ita.ion in fema.e reproductive tra.t. While the fa.tors responsible for the regula.ion of these sequentia. ma.ura.iona. events a.e undoubtedly complex, emerging resea.ch ha. identified the molecula. cha.erone, hea. shock protein a. （HSPa.）, a. a.key regula.or of these events in huma. sperma.ozoa. HSPa. is a.testis-enriched member of the 70 kDa.hea. shock protein fa.ily tha. promotes the folding, tra.sport, a.d a.sembly of protein complexes a.d ha. been positively correla.ed with in vitro fertiliza.ion （IVF） success. Furthermore, reduced expression of HSPa. from the huma. sperm proteome lea.s to a. impa.red ca.a.ity for cumulus ma.rix dispersa., sperm-egg recognition a.d fertiliza.ion following both IVF a.d ICSI. In this review, we consider the evidence supporting the role of HSPa. in sperm function a.d explore the potentia. mecha.isms by which it is depleted in the sperma.ozoa.of infertile pa.ients. Such informa.ion offers novel insights into the molecula. mecha.isms governing sperm function.

关键词： egg fertiliza.ion hea. shock protein a. molecula. cha.erone sperm sperm-egg intera.tions

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太极拳预防老年人跌倒研究成果在多元文化社区的推广应用(英文)

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Journa. of Sport a.d Hea.th Science 2014年第1期3卷 27-31+1-2+64页

作者： Da.id Fink kate Houston Metropolita. a.ea.a.ency on a.ing

老年人跌倒在明尼苏达州是一个严重的公共健康问题,已成为非常显著的健康风险。已有很多研究证明,跌倒可以通过运动预防,因此,有越来越多的老龄人口服务组织开始公共健康方面的尝试,把实证研究结果转化和传播到社区当中。但这些尝试在... 详细信息

老年人跌倒在明尼苏达州是一个严重的公共健康问题,已成为非常显著的健康风险。已有很多研究证明,跌倒可以通过运动预防,因此,有越来越多的老龄人口服务组织开始公共健康方面的尝试,把实证研究结果转化和传播到社区当中。但这些尝试在包括不同文化背景和语言的老年人社区会遇到很多挑战。本文简要介绍了一项通过美国明尼苏达州明尼阿波里斯/圣保罗市区当地老年机构开展的实证跌倒预防试点研究项目——"太极拳:运动改善平衡",分析了其启动、实施、进程和结果。这项计划总体上得以成功实施,被当地亚裔社区服务机构采纳,也在相当程度上被东非裔非英语老年人社区服务机构接受。该计划开设了社区双语教练引导课程,从而引起作为干预目标的老年人广泛参与,以此提高身体活动能力。这项试点研究表明,"太极拳:运动改善平衡"项目成果可以通过在非英语社区使用双语教练取得推广应用效果。

关键词：平衡传播跌倒老年人太极拳

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