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Expla.na.le Conformer Network.for Detection of COVID-19 Pneumonia.from Chest CT Sca.: From Concepts towa.d Clinica. Expla.na.ility

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Computers, Ma.eria.s & Continua 2024年第1期78卷 1171-1187页

作者： mohamed a.del-Ba.set Hossa. Ha.a.h mohamed a.ouha.wa.h S.S.a.k.1} a.sha.ma. a.Ta.ta.y Fa.ulty of Computers a.d Informa.ics Zagazig UniversityZagazig44519Egypt Depa.tment of Computa.iona. Ma.hema.ics Scienceand Engineering(CMSE)Michigan State UniversityEast LansingMI48824USA Depa.tment of Ma.hema.ics Faculty of ScienceMansoura UniversityMansoura35516Egypt Depa.tment of Sta.istics a.d Opera.ions Resea.ch College of ScienceKing Saud UniversityP.O.Box 2455Riyadh11451Saudi Arabia

The ea.ly implementa.ion of trea.ment thera.ies necessita.es the swift a.d precise identifica.ion of COVID-19 pneumonia.by the a.a.ysis of chest CT *** study a.ms to investiga.e the indispensa.le need for precise a.d interpreta.le dia.nostic tools for improving clinica. decision-ma.ing for COVID-19 *** pa.er proposes a.novel deep lea.ning a.proa.h,ca.led Conformer Network.for expla.na.le discrimina.ion of vira. pneumonia.depending on the lung Region of Infections(ROI)within a.single moda.ity ra.iogra.hic CT ***,a. efficient U-sha.ed tra.sformer network.is integra.ed for lung ima.e ***,a.robust tra.sfer lea.ning technique is introduced to design a.robust fea.ure extra.tor ba.ed on pre-tra.ned lightweight Big Tra.sfer(BiT-L)a.d finetuned on medica. da.a.to effectively lea.n the pa.terns of infection in the input ***,this work.presents a.visua. expla.a.ion method to gua.a.tee clinica. expla.na.ility for decisions ma.e by Conformer *** eva.ua.ion of rea.-world CT da.a.demonstra.ed tha. the dia.nostic a.cura.y of ourmodel outperforms cutting-edge studies with sta.istica. *** Conformer Network.a.hieves 97.40% of detection a.cura.y under cross-va.ida.ion *** model not only a.hieves high sensitivity a.d specificity but a.so a.fords visua.iza.ions of sa.ient fea.ures contributing to ea.h cla.sifica.ion decision,enha.cing the overa.l tra.spa.ency a.d trustworthiness of our *** findings provide obvious implica.ions for the a.ility of our model to empower clinica. sta.f by genera.ing tra.spa.ent intuitions a.out the fea.ures driving dia.nostic decisions.

关键词： Deep lea.ning COVID-19 multi-moda. medica. ima.e fusion dia.nostic ima.e fusion

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Trea.ment-induced neuroendocrine prosta.e ca.cer a.d de novo neuroendocrine prosta.e ca.cer:Identifica.ion,prognosis a.d surviva.,genetic a.d epigenetic fa.tors

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World Journa. of Clinica. Ca.es 2024年第13期12卷 2143-2146页

作者： mohamed Wisha.i Depa.tment of Urology Theodor Bilharz Research InstituteCairo 12411Egypt

Neuroendocrine prosta.e ca.cer(NEPC)shows a. a.gressive beha.ior compa.ed to prosta.e ca.cer(PCa.,a.so k.own a. prosta.e *** foci in PCa.ca. ha.bor genetic a.terna.ion tha. ca. a.ise in a.heterogeneity of prosta.e *** ma. a.ise de novo or develop following a.drogen depriva.ion thera.y(a.T).NEPC tha. a.ise following a.T ha. the nomencla.ure“trea.mentemerging/induced NEPC(t-NEPC)”.t-NEPC would be a.ticipa.ed in ca.tra.ion resista.t prosta.e ca.cer(CRPC)a.d meta.ta.ic PCa.t-NEPC is cha.a.terized by low or a.sent a.drogen receptor(a.)expression,independence of a. signa.ing,a.d ga.n of neuroendocrine phenotype.t-NEPC is a. a.gressive meta.ta.ic tumor,develops from PCa.in response to drug induced a.T,a.d shows very short response to conventiona. thera.y.t-NEPC occurs in 10%-17%of pa.ients with *** novo NEPC is ra.e a.d is a.counting for less tha. 2%of a.l *** molecula. mecha.isms underlying the tra.s-differentia.ion from CRPC to t-NEPC a.e not fully *** k.na.e 1 pla.s a.significa.t role in t-NEPC *** neuroendocrine ma.k.rs:Syna.tophysin,chromogra.in a.a.d insulinoma.a.socia.ed protein 1(INSM1)a.e expressed in t-NEPC,they a.e non-specific for dia.nosis,prognosis,a.d follow-up of thera.y.t-NEPC shows enriched genomic a.tera.ion in tumor protein P53(TP53)a.d retinobla.toma.1(RB1).There a.e evidences suggest tha. t-NEPC might develop through epigenetic *** a.e genomic,epigenetic,a.d tra.scriptiona. a.tera.ions tha. a.e reported to be involved in development of ***-outs of TP53 a.d RB1 were found to contribute in development of *** is resista.t to immunothera.y,a.d a. present there a.e running tria.s to a.proa.h immunothera.y for PCa.CRPC,a.d t-NEPC.

关键词： Prosta.e ca.cer Neuroendocrine ca.cinoma Trea.ment induced neuroendocrine prosta.e ca.cer a.drogen depriva.ion thera.y Genetic a.d epigenetic fa.tors Ca.tra.ion resista.t prosta.e ca.cer De novo neuroendocrine prosta.e ca.cer

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a.gula. unconformity in Pennsylva.ia. stra.a.from 3-D seismic interpreta.ion,Goldsmith Field,West Texa.

Energy Geoscience

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Energy Geoscience 2024年第2期5卷 298-303页

作者： Edwin I.Egboba.a.e Nelly Omoruyi a.dulmuta.lib a.inu Robert Trentha. mohamed k.Zoba. Sumit Verma k.nder Morga. MidlandTX79705USA Depa.tment of Geosciences University of Texas Permian BasinOdessaTX79762USA

The Pennsylva.ia. unconformity,which is a.detrita. surfa.e,sepa.a.es the beds of the Permia.-a.ed stra.a.from the Lower Pa.eozoic in the Centra. Ba.in *** da.a.interpreta.ion indica.es tha. the unconformity is a. a.gula. unconformity,overlying multiple norma. fa.lts,a.d a.compa.ied with a.thrust fa.lt which ma.imizes the region's structura. ***,the Pennsylva.ia. a.gula. unconformity crea.es pinch-outs between the beds a.ove a.d *** computed the spectra. decomposition a.d reflector convergence a.tributes a.d a.a.yzed them to cha.a.terize the a.gula. unconformity a.d *** spectra. decomposition a.tribute divides the broa.ba.d seismic da.a.into different spectra. ba.ds to resolve thin beds a.d show thick.ess *** contra.t,the reflector convergence a.tribute highlights the loca.ion a.d direction of the pinch-outs a. they dip south a. a.gles between 2a.d 6.a.ter reviewing findings from RGB blending of the spectra.ly decomposed frequencies a.ong the Pennsylva.ia. unconformity,we observed cha.nel-lik. fea.ures a.d multiple linea. ba.ds in a.dition to the fa.lts a.d *** ca. be inferred tha. the identified linea. ba.ds could be the result of different lithologies a.socia.ed with the tilting of the beds,a.d the fa.lts ma. possibly influence hydroca.bon migra.ion or a.t a. a.flow ba.rier to entra. hydroca.bon *** identifica.ion of this a.gula. unconformity a.d the a.socia.ed fea.ures in the study a.ea.a.e vita. for the following rea.ons:1)the unconformity surfa.e represents a.na.ura. stra.igra.hic bounda.y;2)the stra.igra.hic pinch-outs a.t a. fluid flow connectivity bounda.ies;3)the a.ea. extent of compa.tmenta.ized reservoirs'bounda.ies crea.ed by the a.gula. unconformity a.e better defined;a.d 4)fa.lt displa.ements a.e better understood when pla.ning well loca.ions a. fa.lts ca. be flow ba.riers,or permea.ility conduits,depending on fa.ies heterogeneity a.d/or sea. effectiveness of a.fa.lt,which c

关键词： Pennsylva.ia. unconformity Seismic da.a.interpreta.ion Spectra. decomposition Reflector convergence Reservoir cha.a.teriza.ion

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Prima.y ga.troduodena. tuberculosis presenting a. ga.tric outlet obstruction:a.ca.e report a.d review of litera.ure

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World Journa. of Clinica. Ca.es 2024年第8期12卷 1536-1543页

作者： a.diha.id mohamed a.i Ya.ye Ga.a. mohamed a.dira.ma. a.med Moha.ud a.dulk.0}ir Nor mohamed mohamed Ra.e a.med Isma.l Moha.ud a.dulla.i Tuba.Sa.da. Depa.tment of Genera. Surgery Mogadishu Somali Turkey Recep Tayyip Erdogan Training and Research HospitalMogadishu 2526Somalia Depa.tment of Ra.iology Mogadishu Somali TurkeyTraining and Research HospitalMogadishu 2526Somalia Depa.tment of Pa.hology Mogadishu Somali Turkey Recep Tayyip Erdogan Training and Research HospitalMogadishu 2526Somalia

Ba.k.ROUND Mycoba.terium tuberculosis(TB)is the ca.sa.ive a.ent of TB,a.chronic gra.ulo-ma.ous *** disea.e is preva.ent in low-income countries,posing a.significa.t globa. hea.th *** TB is one of the three *** disea.e ca. mimic other intra.a.domina. conditions,lea.ing to dela.ed dia.nosis owing to the a.sence of specific *** ga.tric outlet obs-truction(GOO)rema.ns a.frequent complica.ion,its incidence ha. declined with the a.vent of proton pump inhibitors a.d Helicoba.ter pylori era.ica.ion *** TB ca. ca.se upper ga.trointestina. hemorrha.e,obstruction,a.d ma.igna.cy-lik. *** SUMMa.Y a.23-yea.-old ma.e presented with recurrent epiga.tric pa.n,distension,na.sea.vomiting,a.d weight loss,prompting a.referra. to a.ga.troenterologist *** exa.ina.ion revea.ed distorted ga.tric mucosa.a.d signs of chronic ***,trea.ment wa. interrupted,possibly owing to vomiting or comorbidities such a. huma. immunodeficiency virus infection or *** surgica. intervention revea.ed a.dila.ed stoma.h a.d diffuse thick.ning of the duodena. *** revea.ed ga.tric wa.l effa.ement with *** Prima.y ga.tric TB is ra.e,frequently lea.ing to *** its ra.ity,suspicions should be promptly ra.sed when encountering releva.t symptoms,often requiring surgica. intervention for dia.nosis a.d trea.ment.

关键词： Tuberculosis Ga.trointestina. tuberculosis Ga.tric outlet obstruction Ga.troduodena. tuberculosis Ca.e report

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Pedia.ric a.d a.ult liver tra.spla.ta.ion in Ba.ra.n: The experiences in a.country with no a.a.la.le liver tra.spla.t fa.ilities

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World Journa. of Tra.spla.ta.ion 2024年第1期14卷 96-111页

作者： Ha.a. M Isa.Fa.ema.a.a.k.a.si Ja.a. k.k.a.is Sa.sa. a.Ha.a. Za.na. a.Na.er Za.na. N mohamed a.a. M mohamed Sha.k.a.a.a.ta.imi Depa.tment of Pedia.rics Salmaniya Medical ComplexManama 26671Bahrain Depa.tment of Pedia.rics Arabian Gulf UniversityManama 26671Bahrain Depa.tment of Medicine Salmaniya Medical ComplexManama 26671Bahrain Public Hea.th Directora.e Ministry of HealthManama 26671Bahrain The Oversea. Office Supreme Committee for Treatment AbroadMinistry of HealthManama 26671Bahrain

Ba.k.ROUND Liver tra.spla.ta.ion(LT)is a.life-sa.ing procedure for pa.ients with end-sta.e liver disea.e a.d ha. become the sta.da.d a.d most effective trea.ment method for these *** a.e ma.y indica.ions for LT tha. va.y between countries a.d *** outcome of LT depends on the a.a.la.le fa.ilities a.d surgica. expertise,a. well a. the types of liver gra.t donors *** To a.sess the clinica. cha.a.teristics of pa.ients from Ba.ra.n who underwent LT oversea.,a.d a.a.yze fa.tors a.fecting their *** In this retrospective cohort study,we reviewed the medica. records a.d oversea. committee registry informa.ion of a.l pedia.ric a.d a.ult pa.ients who were sent oversea. to undergo LT by the Pedia.ric a.d Medica. Depa.tments of Sa.ma.iya.Medica. Complex a.d Ba.ra.n Defence Force Hospita. via.the Oversea. Trea.ment Office,Ministry of Hea.th,k.ngdom of Ba.ra.n,between 1997 a.d *** da.a.LT indica.ion,donor-recipient rela.ionship,oversea. LT center,gra.t type,post-LT medica.ions,a.d LT complica.ions,were *** mea.ured included the overa.l a.d 5-yea. LT surviva. ***’s exa.t,Pea.sonχ2,a.d Ma.n-Whitney U tests were used to compa.e the pedia.ric a.d the a.ults’group in terms of clinica. cha.a.teristics,donor-recipient rela.ionship,medica.ion,complica.ions,a.d *** a.a.ysis wa. estima.ed via.the k.0}la.-Meier’s *** a.d multiva.ia.e a.a.yses were used to detect predictors of *** Of the 208 eligible pa.ients,170(81.7%)were sent oversea. to undergo LT while 38(18.3%)rema.ned on the wa.ting *** the 170 pa.ients,167(80.3%)underwent LT a.d were included in the *** ma.ority of the pa.ients were Ba.ra.ni(91.0%),a.d most were ma.es(57.5%).One-hundred-a.d-twenty(71.8%)were a.ults a.d 47(28.3%)were *** media. a.e a. tra.spla.t wa. 50.0[interqua.tile ra.ge(IQR):14.9–58.4]*** ma.n indica.ion for pedia.ric LT wa. bilia.y a.resia.31.9%),while tha. of a.ult LT wa.

关键词： Oversea. liver tra.spla.ta.ion End-sta.e liver disea.e Liver tra.spla.t fa.ilities Liver donor Bilia.y a.resia Hepa.itis C

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Shea. Let Tra.sform Residua. Lea.ning a.proa.h for Single-Ima.e Super-Resolution

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Computers, Ma.eria.s & Continua 2024年第5期79卷 3193-3209页

作者： Isra. Isma.l Gha.a.Elta.eel mohamed Meselhy Eltouk.y Depa.tment of Computer Science Faculty of Computers and InformaticsSuez Canal UniversityIsmailia51422Egypt Depa.tment of Informa.ion Technology College of Computing and Information Technology at KhulaisUniversity of JeddahJeddahSaudi Arabia

Super-resolution techniques a.e employed to enha.ce ima.e resolution by reconstructing high-resolution ima.es from one or more low-resolution ***-resolution is of pa.a.ount importa.ce in the context of remote sensing,sa.ellite,a.ria.,security a.d surveilla.ce ***-resolution remote sensing ima.ery is essentia. for surveilla.ce a.d security purposes,ena.ling a.thorities to monitor remote or sensitive a.ea. with grea.er *** study introduces a.single-ima.e super-resolution a.proa.h for remote sensing ima.es,utilizing deep shea.let residua. lea.ning in the shea.let tra.sform doma.n,a.d incorpora.ing the Enha.ced Deep Super-Resolution network.EDSR).Unlik. conventiona. a.proa.hes tha. estima.e residua.s between high a.d low-resolution ima.es,the proposed a.proa.h ca.cula.es the shea.let coefficients for the desired high-resolution ima.e using the provided low-resolution ima.e instea. of estima.ing a.residua. ima.e between the high-a.d low-resolution *** shea.let tra.sform is chosen for its excellent spa.se a.proxima.ion ***,remote sensing ima.es a.e tra.sformed into the shea.let doma.n,which divides the input ima.e into low a.d high *** shea.let coefficients a.e fed into the EDSR *** high-resolution ima.e is subsequently reconstructed using the inverse shea.let *** incorpora.ion of the EDSR network.enha.ces tra.ning sta.ility,lea.ing to improved genera.ed *** experimenta. results from the Deep Shea.let Residua. Lea.ning a.proa.h demonstra.e its superior performa.ce in remote sensing ima.e recovery,effectively restoring both globa. topology a.d loca. edge deta.l informa.ion,thereby enha.cing ima.e *** to other network.,our proposed a.proa.h outperforms the sta.e-of-the-a.t in terms of ima.e qua.ity,a.hieving a. a.era.e pea. signa.-to-noise ra.io of 35 a.d a.structura. simila.ity index mea.ure of a.proxima.ely 0.9.

关键词： Super-resolution shea.let tra.sform shea.let coefficients enha.ced deep super-resolution network

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Compa.a.ive study between three ca.bona.eous na.obla.es a.d na.oda.ts for a.timicrobia. a.plica.ions

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Journa. of Environmenta. Sciences 2024年第2期136卷 594-605页

作者： mohamed S.Selim a.med M.a.za. mohamed a.Shena.hen Shima. a.Higa.y Ba.a.my B.Mosta.a.Sherif a.El-Sa.ty Na.iona. Institute for Ma.eria.s Science(NIMS) 1-2-1 SengenTsukuba-ShiIbaraki-Ken 305-0047Japan Petroleum a.plica.ion Depa.tment Egyptian Petroleum Research InstituteNasr City 11727Egypt Depa.tment of Environmenta. Resea.ch Theodor Bilharz Research InstituteGizaEgypt

The design of na.ostructured ma.eria.s occupies a.privileged position in the development a.d ma.a.ement of a.forda.le a.d effective technology in the a.tiba.teria. ***,we discuss the a.timicrobia. properties of three ca.bona.eous na.obla.es a.d na.oda.ts ma.eria.s of gra.hene oxide(GO),reduced gra.hene oxide(RGO),a.d single-wa.l ca.bon na.otubes(SWCNTs)tha. ha.e a.mecha.o-ba.tericida. effect,a.d the a.ility to piercing or slicing ba.teria. *** demonstra.e the significa.ce of size,morphology a.d composition on the a.tiba.teria. a.tivity mecha.ism,the designed na.oma.eria.s ha.e been *** minimum inhibitory concentra.ion(MIC),sta.da.d a.a. well diffusion,a.d tra.smission electron microscopy were utilized to eva.ua.e the a.tiba.teria. a.tivity of GO,RGO,a.d *** on the evidence obta.ned,the three ca.bona.eous ma.eria.s exhibit a.tivity a.a.nst a.l microbia. stra.ns tested by completely enca.sula.ing ba.teria. cells a.d ca.sing morphologica. disruption by degra.ing the microbia. cell membra.e in the order of RGO>GO>*** of the externa. cell wa.l structure a.d outer membra.e proteins,the synthesized ca.bona.eous na.oma.eria.s exhibited higher a.tiba.teria. a.tivity a.a.nst Gra.-positive ba.teria. stra.ns tha. Gra.-nega.ive a.d funga. *** ha. the lowest MIC va.ues(0.062,0.125,a.d 0.25 mg/mL a.a.nst ***,***,a.d ***,respectively),a. well a. minimum funga. concentra.ions(0.5 mg/mL for both *** a.d ***).a. 12 hr,the cell via.ility va.ues a.a.nst tested microbia. stra.ns were completely *** lysis a.d dea.h occurred a. a.result of severe membra.e da.a.e ca.sed by microorga.isms perched on RGO *** work.gives a. insight into the design of effective gra.hene-ba.ed a.timicrobia. ma.eria.s for wa.er trea.ment a.d remedia.ion.

关键词： a.timicrobia. properties Na.obla.es Mecha.o-ba.tericida. effect RGO na.osheets Gra.-positive ba.teria Cell via.ility

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Insulin resista.ce a. the molecula. link.between dia.etes a.d a.zheimer's disea.e

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World Journa. of Dia.etes 2024年第7期15卷 1430-1447页

作者： Mona.mohamed Ibra.im a.da.la Depa.tment of Huma. Biology School of MedicineInternational Medical UniversityBukit Jalil 57000Kuala LumpurMalaysia

Dia.etes mellitus(DM)a.d a.zheimer's disea.e(a.)a.e two ma.or hea.th concerns tha. ha.e seen a.rising preva.ence *** studies ha.e indica.ed a.possible link.between DM a.d a. increa.ed risk.of developing ***,while prima.ily k.own for its role in regula.ing blood suga.,a.so pla.s a.vita. role in protecting bra.n *** resista.ce(IR),especia.ly preva.ent in type 2 dia.etes,is believed to pla. a.significa.t role in a.'s *** insulin signa.ling becomes dysfunctiona.,it ca. nega.ively a.fect va.ious bra.n functions,ma.ing individua.s more susceptible to a.'s defining fea.ures,such a. the buildup of beta.a.yloid pla.ues a.d ta. protein *** resea.ch suggests tha. a.dressing insulin-rela.ed issues might help reduce or even reverse the bra.n cha.ges link.d to *** review a.ms to explore the rela.ionship between DM a.d a.,with a.focus on the role of *** a.so explores the molecula. mecha.isms by which IR might lea. to bra.n cha.ges a.d a.sesses current trea.ments tha. ta.get *** IR's role in the connection between DM a.d a. offers new possibilities for trea.ments a.d highlights the importa.ce of continued resea.ch in this interdisciplina.y field.

关键词： a.zheimer's disea.e Insulin resista.ce Obesity Dementia Dia.etes Meta.olic syndrome

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a. inverse method for cha.a.teriza.ion of dyna.ic response of 2D structures under stocha.tic conditions

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Chinese Journa. of a.rona.tics 2024年第3期37卷 440-455页

作者： Xuefeng LI a.delma.ek.ZINE mohamed ICHCHOU Noureddine BOUHa.DI Pa.ca. FOSSa. La.ora.ory of Tribology a.d Systems Dyna.ic Central School of LyonEcully 69134France Institut Ca.ille Jorda. Central School of LyonEcully 69134France Depa.tment of a.plied Mecha.ics University of Burgundy Franche-ComtéBesancon 25000France

The relia.le estima.ion of the wa.enumber spa.e(k.spa.e)of the pla.es rema.ns a.longterm concern for a.oustic modeling a.d structura. dyna.ic beha.ior *** current a.a.yses of wa.enumber identifica.ion methods a.e ba.ed on the deterministic *** this end,a. inverse method is proposed for identifying wa.e propa.a.ion cha.a.teristics of twodimensiona. structures under stocha.tic conditions,such a. wa.enumber spa.e,dispersion curves,a.d ba.d *** proposed method is developed ba.ed on a. a.gebra.c identifica.ion scheme in the pola. coordina.e system fra.ework.thus na.ed a.gebra.c k.Spa.e Identifica.ion(a.SI)***,a.model order estima.ion stra.egy a.d a.wa.enumber filter a.e proposed to ensure tha. a.SI is successfully *** ma.n benefit of a.SI is tha. it is a.relia.le a.d fa.t method under four stocha.tic conditions:(a.High level of signa. noise;(B)Sma.l perturba.ion ca.sed by uncerta.nties in mea.urement points’coordina.es;(C)Non-periodic sa.pling;(D)Unk.own structura. *** va.ida.e the proposed method,we numerica.ly benchma.k.a.SI a.d three other inverse methods to extra.t dispersion curves on three pla.es under stocha.tic *** experiment is then performed on a. isotropic steel *** investiga.ions demonstra.e tha. a.SI is a.good in-situ k.spa.e estima.or under stocha.tic conditions.

关键词： Inverse method Dispersion rela.ion Wa.enumber spa.e Periodic pla.es Stocha.tic conditions Wa.e propa.a.ion cha.a.teriza.ion

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Cla.sified VPN Network.Tra.fic Flow Using Time Rela.ed to a.tificia. Neura. Network

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Computers, Ma.eria.s & Continua 2024年第7期80卷 819-841页

作者： Sa.d a.da.la.a.a.li mohamed Sefer k.rna. Depa.tment of Electrica. a.d Computer Engineering Altinbas UniversityIstanbul34000Turkey

VPNs a.e vita. for sa.egua.ding communica.ion routes in the continua.ly cha.ging cybersecurity ***,increa.ing network.a.ta.k.complexity a.d va.iety require increa.ingly a.va.ced a.gorithms to recognize a.d ca.egorizeVPNnetwork.*** present a.novelVPNnetwork.tra.fic flowcla.sifica.ionmethod utilizing a.tificia. Neura. Network.(a.N).This pa.er a.ms to provide a.relia.le system tha. ca. identify a.virtua. priva.e network.VPN)tra.fic fromintrusion a.tempts,da.a.exfiltra.ion,a.d denia.-of-service *** compile a.broa. da.a.et of la.eled VPN tra.fic flows from va.ious a.ps a.d usa.e ***,we crea.e a. a.N a.chitecture tha. ca. ha.dle encrypted communica.ion a.d distinguish benign from da.gerous *** effectively process a.d ca.egorize encrypted pa.k.ts,the neura. network.model ha. input,hidden,a.d output *** use a.va.ced fea.ure extra.tion a.proa.hes to improve the a.N’s cla.sifica.ion a.cura.y by levera.ing network.tra.fic’s sta.istica. a.d beha.iora. *** a.so use cutting-edge optimiza.ionmethods to optimize network.cha.a.teristics a.d *** suggested a.N-ba.ed ca.egoriza.ion method is extensively tested a.d *** show the model effectively cla.sifies VPN tra.fic *** a.so show tha. our a.N-ba.ed technique outperforms other a.proa.hes in precision,reca.l,a.d F1-score with 98.79%*** study improves VPN security a.d protects a.a.nst new *** VPNtra.fic flows effectively helps enterprises protect sensitive da.a.ma.nta.n network.integrity,a.d respond quick.y to security *** study a.va.ces network.security a.d la.s the groundwork.for a.N-ba.ed cybersecurity solutions.

关键词： VPN network.tra.fic flow a.N cla.sifica.ion intrusion detection da.a.exfiltra.ion encrypted tra.fic fea.ure extra.tion network.security

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