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Liver tra.spla.ta.ion is beneficia. rega.dless of cirrhosis sta.e or a.ute-on-chronic liver fa.lure gra.e:a.single-center experience

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World Journa. of Ga.troenterology 2022年第40期28卷 5881-5892页

作者： Edua.do Cerva.tes-a.va.ez Ma.io Vila.oba.Na.ha.y Limon-de la.Rosa.Osvely Mendez-guerrero Da.id Kershenobich a.do Torre Na.u Na.a.ro-a.va.ez PECEM Facultad de MedicinaUniversidad Nacional Autónoma de MéxicoMexico City 14080Mexico Depa.tment of Ga.troenterology Instituto Nacional de Ciencias Médicas y Nutrición Salvador ZubiránMexico City 14080Mexico Depa.tment of Tra.pla.t Instituto Nacional de Ciencias Médicas y Nutrición Salvador ZubiránMexico City 14080Mexico Depa.tment of Molecula. Biology Universidad Panamericana School of MedicineMexico City 03920Mexico Depa.tment of Surgery University of Colorado Anschutz Medical CampusDenverCO 80045United States

Ba.KGROUND Liver tra.spla.ta.ion for the most critica.ly ill rema.ns controversia.;however,it is currently the only cura.ive trea.ment *** To a.sess immedia.e posttra.spla.t outcomes a.d compa.e the short(1 yea.)a.d long-term(6 yea.s)posttra.spla.t surviva. a.ong cirrhotic pa.ients stra.ified by disea.e *** We included cirrhotic pa.ients undergoing liver tra.spla.ta.ion between 2015 a.d 2019 a.d ca.egorized them into compensa.ed cirrhosis(CC),decompensa.ed cirrhosis(DC),a.d a.ute-on-chronic liver fa.lure(a.LF).a.LF wa. further divided into severity *** prima.y outcomes of interest were tota. da.s of intensive ca.e unit(ICU)a.d hospita. sta.,development of complica.ions a.d posttra.spla.t surviva. a. 1 a.d 6 *** 235 pa.ients underwent liver tra.spla.ta.ion(CC=11,DC=129 a.d a.LF=95).Pa.ients with a.LF ha. a.significa.tly longer hospita. sta.[8.0(6.0-13.0)vs CC,6.0(3.0-7.0),a.d DC 7.0(4.5-10.0);P=0.01]a.d developed more infection-rela.ed complica.ions[47(49.5%),vs CC,1(9.1%)a.d DC,38(29.5%);Pa.spla.t surviva. a. 1-a.d 6-yea.s wa. simila. a.ong groups(P=0.60 a.d P=0.90,respectively).a.LF pa.ients stra.ified a.cording to a.LF gra.e[a.LF-1 n=40(42.1%),a.LF-2 n=33(34.7%)a.d a.LF-3 n=22(23.2%)],ha. simila. ICU a.d hospita. sta. length(P=0.68,P=0.54),a. well a. compa.a.le frequencies of overa.l a.d infectious posttra.spla.t complica.ions(P=0.58,P=0.80).There wa. no surviva. difference between a.LF gra.es a. 1 yea. a.d 6 yea.s(P=0.40 a.d P=0.15).CONCLUSION Pa.ients ma. benefit from liver tra.spla.ta.ion rega.dless of the cirrhosis *** pa.ients ha.e a.longer hospita. sta. a.d frequency of infectious complica.ions;however,excellent,a.d compa.a.le 1 a.d 6-yea. surviva. ra.es support their enlisting a.d tra.spla.ta.ion including those with a.LF-3.

关键词： Liver tra.spla.ta.ion a.ute-on-chronic liver fa.lure Prognosis Surviva. a.a.ysis Critica. ca.e

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The huma. a.plica.ion of gene thera.y to re-progra. T-cell specificity using chimeric a.tigen receptors

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Chinese Journa. of Ca.cer 2014年第9期33卷 421-433页

作者： a.a. D guerrero Judy S Moyes La.rence JN Cooper Division of Pedia.rics The University of Texas MD Anderson Cancer Center The University of Texa. Gra.ua.e School of Biomedica. Sciences

The a.optive tra.sfer of T cells is a.promising a.proa.h to trea. ca.cers. Prima.y huma. T cells ca. be modified using vira. a.d non-vira. vectors to promote the specific ta.geting of ca.cer cells via.the introduction of exogenous T-cell receptors(TCRs) or chimeric a.tigen receptors(Ca.s). This gene tra.sfer displa.s the potentia. to increa.e the specificity a.d potency of the a.tica.cer response while decrea.ing the systemic a.verse effects tha. a.ise from conventiona. trea.ments tha. ta.get both ca.cerous a.d hea.thy cells. This review highlights the genera.ion of clinica.-gra.e T cells expressing Ca.s for immunothera.y, the use of these cells to ta.get B-cell ma.igna.cies a.d, pa.ticula.ly, the first clinica. tria.s deploying the Sleeping Bea.ty gene tra.sfer system, which engineers T cells to ta.get CD19+ leukemia.a.d non-Hodgkin's lymphoma.

关键词： T细胞受体基因治疗异性重新编程抗原嵌合基因转移系统非病毒载体

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Synchroniza.ion of Robot Ma.ipula.ors a.tua.ed By Induction Motors with Velocity Estima.or

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Computer Modeling in Engineering & Sciences 2019年第11期121卷 609-630页

作者： Felipe J.Torres Gera.do V.guerrero Ca.los D.Ga.cía.Rica.do Za.a.a.Yoe Ma.io a.Ga.cía.a.olfo R.López University of Gua.a.ua.o Division of Engineering Campus Irapuato-SalamancaCarretera Salamanca-Valle de Santiago km 3.5+1.8GuanajuatoSalamanca36885México Na.iona. Technologica. of Mexico/Na.iona. Center of Resea.ch a.d Technologica. Development Av.Palmira S/N colonia PalmiraMorelosCuernavaca62490México School of Engineering a.d Sciences Monterrey TechnologicalPuente 222 Ejidos de HuipulcoCiudad de México14380México Superior Technologica. Institute of Ira.ua.o Carretera Irapuato-Silao km 12.5GuanajuatoIrapuato36821México

a.complete modeling(including the a.tua.or dyna.ics)of a.robot ma.ipula.or tha. uses three-pha.e induction motors is presented in this pa.er.a.control scheme is designed to synchronize robot ma.ipula.ors a.tua.ed by induction motors under a.ma.tersla.e scheme in the ca.e where the joint velocity of the sla.e robots is *** of the resea.ch on the synchroniza.ion of robot ma.ipula.ors a.sumes the use of idea. a.tua.ors to drive the joints;for tha. rea.on,in this work,a.three-pha.e induction motor is considered to be a.direct-drive a.tua.or for ea.h *** entire model of the ma.ed system is obta.ned by a.combina.ion of the dyna.ics of the induction motor a.d robot ***,the synchroniza.ion control a.gorithm for a.ma.ter-sla.e scheme in both the joint spa.e a.d workspa.e of robot ma.ipula.ors driven by induction motors is *** observer ba.ed on the entire model is proposed to estima.e the joint velocity of the sla.e robot *** the Lya.unov criterion,a.sta.ility a.a.ysis of the synchroniza.ion control with a.velocity estima.or is *** a.a.ytica. results show the synchroniza.ion a.d estima.ion errors a.e globa.ly,uniformly,a.d ultima.ely *** with multiple robots demonstra.e the performa.ce of the proposed control a.gorithm.

关键词： Synchroniza.ion robot ma.ipula.or induction motor Lya.unov sta.ility observer ba.ed on the model

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Rotorcra.t with a.3DOF Rigid Ma.ipula.or:Qua.ernion-ba.ed Modeling a.d Rea.-time Control Tolera.t to Multi-body Couplings

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Interna.iona. Journa. of a.toma.ion a.d computing 2018年第5期15卷 547-558页

作者： J.a.va.ez-Munoz N.Ma.cha.d J.F.guerrero-Ca.tella.os J.J.Tellez-Guzma. J.Esca.eno M.Ra.otondra.e Polytechnic Institute of a.va.ced Sciences FR 94200 ParisFrance Univ.Grenoble a.pes GIPSA-LabFR-38000 GrenobleFrance a.tonomous University of Puebla.BUa.) Faculty of ElectronicsMX 72570 PueblaMexico University of Limoges ENSIL-ENSCI XLIM Laboratory UMR CNRS 7252Parc Ester Technopole16 rue AtlantisLimoges 87068France FEMTO-ST Institute UMR CNRS-UFC/ENSMM/UTBMAutomatic Control and Micro-Mechatronic DepartmentFR BesanconFrance

This pa.er proposes a.simple solution for the sta.iliza.ion of a.mini-qua.copter ca.rying a.3DoF（degrees of freedom） ma.ipula.or robot in order to enha.ce its a.hieva.le workspa.e a.d a.plica.ion profile. Since the motion of the a.m induces torques which degra.e the sta.ility of the system, in the present work, we consider the sta.iliza.ion of both subsystems： the qua.copter a.d the robotic a.m. The ma.hema.ica. model of the system is ba.ed on qua.ernions. Likewise, a. a.titude control la. consisting of a.bounded qua.ernion-ba.ed feedba.k sta.ilizes the qua.copter to a.desired a.titude while the a.m is evolving. The next sta.e is the tra.sla.iona. dyna.ics which is simplified for control（nonlinea.） design purposes. The a.orementioned controllers a.e ba.ed on sa.ura.ion functions whose sta.ility is explicitly proved in the Lya.unov sense. Fina.ly, experimenta. results a.d a.sta.istica. study va.ida.e the proposed control stra.egy.

关键词： Observer-ba.ed control qua.ernion a.d Newton-Euler modeling bounded-input control a.ria. ma.ipula.or disturba.cerejection.

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The Effect of Bra.n Gym on Globa. Cognitive Function of Institutiona.ized Older People

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Interna.iona. Journa. of Menta. Hea.th Promotion 2022年第3期24卷 375-383页

作者： a.a.eli Ca.o-Estra.a.a.a.eli Jimenez-Mendoza.Denny Contrera.-guerrero Ma.io Herna.des-a.eja.dro a.dres Sa.a.-Ca.a. Escuela.Superior de Tla.uelilpa. Universidad Autónoma del Estado de HidalgoTlahuelilpanHidalgoMéxico Escuela.Na.iona. de Enfermería.y Obstetricia.Universida. Na.iona. a.tónoma.de México Mexico CityMéxico Depa.tomento de Bioingenieria Unidad Profesional Interdisciplinaria de Biotecnología del Instituto Politecnico Nacional(UPIBIIPN)Mexico CityMexico Instituto de Ciencia. de la.Sa.ud.Universida. a.tónoma.del Esta.o de Hida.go.Pa.huca Hidalgo.México.Scuela Superior de TlahuelilpanUniversidad Autónoma del Estado de HidalgoTlahuelilpanHidalgoMéxico

Cognitive function of older a.ults is influenced by severa. fa.tors such a. a.e,sex,educa.ion,a.d physica. a.tivity so tha. it ca. impa.t the decrea.e in progressive cognitive *** is necessa.y to implement cognitive tra.ning in old people’s ca.e to prevent or dela. the onset of a.e-rela.ed cognitive *** gym is a.series of simple motion exercises a.d is a. a.terna.ive thera.y tha. stimula.es the *** study a.ms to eva.ua.e the effect of bra.n gym a. a.cognitive tra.ning intervention on globa. cognitive functioning of institutiona.ized older *** study is a.non-ra.domized qua.i-experimenta. one using pre-a.d post-test control group *** pa.ticipa.ts of the study were 65 yea.s old or older who ha. been pa.t of gerontologica. centers from a.loca. *** were divided into two groups:control a.d intervention,ea.h one with 15 ***-Menta. Sta.e Exa.ina.ion wa. a.plied to the sa.ple before a.d a.ter the cognitive *** bra.n gym tra.ning consists of bi-weekly group meeting for 12 weeks,la.ting 50 min *** trea.ed group ha. a.significa.tly better globa. cognitive ***(memory),orienta.ion a.d la.gua.e skills were the doma.ns with the most significa.t cha.ges(pa.d,no significa.t cha.ges were found in the pa.ticipa.ts of control groups during post *** results suggest tha. cognitive tra.ning ba.ed in bra.n gym improves globa. cognitive function of institutiona.ized older people lea.e type your a.stra.t *** of a.resea.ch pa.er is typica.ly 200 to 400 words in length,a.d 150 to 300 words for a.review *** sha.l be running continuously(not structured)a.d sha.l not include reference *** tha. a.pea. only once in the a.stra.t should be defined in *** a.brevia.ions a.pea. more tha. once,the full definitions should be provided first before they ca. be used elsewhere.

关键词： Cognitive function bra.n gymna.tic older people gerontologica. center physica. a.tivity

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Experimenta.ly rea.izing efficient qua.tum control with reinforcement lea.ning

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Science China.Physics,Mecha.ics & a.tronomy) 2022年第5期65卷 13-20页

作者： Ming-Zhong a. Yongcheng Ding Yue Ba. JoséDMa.tín-guerrero Jorge Ca.a.ova.Jin-Ming Cui Yun-Feng Hua.g Xi Chen Chua.-Feng Li Gua.g-Ca. Guo Ca. Key La.ora.ory of Qua.tum Informa.ion University of Science and Technology of ChinaHefei 230026China Ca. Center For Excellence in Qua.tum Informa.ion a.d Qua.tum Physics University of Science and Technology of ChinaHefei 230026China Interna.iona. Center of Qua.tum a.tifcia. Intelligence for Science a.d Technology(Qu a.tist)a.d Depa.tment of Physics Shanghai UniversityShanghai 200444China Depa.tment of Physica. Chemistry University of the Basque Country UPV/EHUBilbao 48080Spai School of Ma.eria.s Science a.d Engineering Shanghai UniversityShanghai 200444China IDa. Electronic Engineering DepartmentUniversity of ValenciaValencia 46100Spain IKERBa.QUE Basque Foundation for ScienceBilbao 48009Spain

We experimenta.ly investiga.e deep reinforcement lea.ning(DRL)a. a. a.tificia. intelligence a.proa.h to control a.qua.tum *** verify tha. DRL explores fa.t a.d robust digita. qua.tum controls with opera.ion time a.a.ytica.ly hinted by shortcuts to *** pa.ticula.,the protocol’s robustness a.a.nst both over-rota.ions a.d off-resona.ce errors ca. still be a.hieved simulta.eously without a.y priori *** the thorough compa.ison,we choose the ta.k a. single-qubit flipping,in which va.ious a.a.ytica. methods a.e well-developed a. the benchma.k,ensuring their fea.ibility in the qua.tum system a. ***,a.ga.e opera.ion is demonstra.ed on a.tra.ped^(171) Yb^(+)ion,significa.tly outperforming a.a.ytica. pulses in the ga.e time a.d energy cost with hybrid robustness,a. well a. the fidelity a.ter repetitive opera.ions under time-va.ying stocha.tic *** experiments revea. a.fra.ework of computer-inspired qua.tum control,which ca. be extended to other complica.ed ta.ks without loss of genera.ity.

关键词： qua.tum control reinforcement lea.ning tra.ped ion qua.tum computing noise robustness

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Eva.ua.ion of pig oocyte in vitro ma.ura.ion a.d fertiliza.ion using three gona.otropin-ba.ed hormona. compounds

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a.ia. pa.ific Journa. of Reproduction 2021年第2期10卷 90-97页

作者： Rosa.io Sa.tia.o-Rodriguez a.ma.L.a.va.ez-guerrero Ferna.do Ga.cia.Gonza.ez a.icia.a.ca.ta.-Rodriguez a.fredo Medra.o a.tonomous University of Mexico Sta.e AmecamecaMexico Fa.ulty of Sciences National Autonomous University of MexicoMexico Na.iona. a.tonomous University of Mexico FES Cuautitlan:Km 2.5 Carretera Cuautitlan-Teoloyucan54714 Cuautitlan IzcalliEstado de MexicoMexico

Objective:To eva.ua.e the effect of huma. chorionic gona.otropins(hCG)a.d equine chorionic gona.otropins(eCG)on in vitro gilt oocyte ma.ura.ion a.d embryonic development,using frozen semen for ***:Two independent experiments(6 replica.es ea.h)were ca.ried out to eva.ua.e gilt oocyte ma.ura.ion,a.d fertiliza.ion a.d embryonic development by using ova.ies from a.loca. ***,712 oocytes were ra.domly distributed in four-well dishes to receive Novormon(eCG 5.0 IU),PG600(eCG 5.0 IU a.d hCG 2.5 IU),Chorulon(hCG 5.0 IU),or no *** were incuba.ed with 5%CO2,95%a.r a.d sa.ura.ion humidity a. 39℃for 44 *** of the oocytes to meta.ha.eⅡwa. a.sessed by using the a.eto-orcein *** a.dition,741 oocytes were used a.d ra.domly distributed in four-well dishes,a.d then oocyte ma.ura.ion wa. ca.ried out a. mentioned,but ma.ured oocytes were wa.hed a.d pla.ed in fertiliza.ion medium with frozen-tha.ed *** were co-incuba.ed for 7 h,a.d then wa.hed a.d pla.ed in development medium,a.d incuba.ed for further 7 da.s,a. which time embryonic development wa. *** a.d embryo development media.were not supplemented with the studied ***:Novormon(eCG)a.d PG600(eCG+hCG)trea.ments significa.tly improved the percenta.es of meta.ha.eⅡoocytes compa.ed to the control group(Pa.significa.t increa.e wa. a.so observed in the young bla.tocyst sta.e between the control group a.d the PG600 trea.ment group(Pa. products Novormon(eCG)a.d PG600(eCG+hCG)ca. obta.n the highest percenta.es of in vitro ma.ura.ion in gilt oocytes;however,this effect is not tra.sferred to fertiliza.ion ra.es.

关键词： Chorionic gona.otropins Embryo Oocyte ma.ura.ion In vitro fertiliza.ion

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Ea.ly Intervention in the Neurodevelopment of Prema.ure Infa.ts during the First Six Months of Life

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Neuroscience & Medicine 2011年第2期2卷 104-109页

作者： Irma.a.va.a.o-guerrero a.rián Pobla.o Erzsebet Ma.osi Ma.ía.Corsi-Ca.rera.Gloria.a. Otero-Ojeda Interdisciplina.y Center for Ea.ly Intervention College of High Studies at Iztacala (UNAM) Clinic of Sleep Disorders National University of Mexico (UNAM) La.ora.ory of Cognitive Neurophysiology National Institute of Rehabilitation (INR)

Objective: Mea.ure the effects of Ea.ly Intervention a. modum Ka.ona.(EI-K) in high-risk prema.ure infa.ts by mea.s of clinica., neurobeha.iora., a.d neurophysiologic tests. Method: We used the a.iel-Tison neurologic exa.ina.ion, the Ba.ley Sca.e of Infa.t Beha.ior, a.d electroencepha.ogra.hy (EEG) recordings a. 42 weeks of conceptiona. a.e, a.d a.ter 6 months of trea.ment EI-K (n = 14) a.d compa.ed these results with those of a.group of infa.ts without ea.ly intervention (nEI) (n = 11). Results: We found better performa.ce of infa.ts in EI-K tha. nEI group a.ter 6 months of trea.ment in neurologic a.d beha.iora. exa.ina.ion mea.urements, but found no differences in EEG compa.isons. Conclusion: Our da.a.suggest significa.t benefit of the use of EI-K progra. over n-EI in the neurologic a.d neurobe-ha.ior exa.ina.ions of prema.ure infa.ts a.ter 6 months of a.e.

关键词： Prema.ure High-risk Infa.ts Ea.ly Intervention Bra.n Pla.ticity

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直流微电网储能系统中带有母线电压跌落补偿功能的负荷功率动态分配方法

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中国电机工程学报 2013年第16期33卷 37-46,20页

作者：陆晓楠孙凯黄立培肖曦 Josep M.guerrero 电力系统及发电设备控制和仿真国家重点实验室(清华大学) 北京市海淀区100084 奥尔堡大学能源技术系

为了充分发挥直流微网中储能系统的作用,提出一种适用于直流分布式储能系统的基于储能单元剩余容量(sta.eof cha.ge,SOC)的改进下垂控制方法。利用该方法可以实现负荷功率在不同储能单元之间的动态分配。该方法中设置传统下垂控制中的... 详细信息

为了充分发挥直流微网中储能系统的作用,提出一种适用于直流分布式储能系统的基于储能单元剩余容量(sta.eof cha.ge,SOC)的改进下垂控制方法。利用该方法可以实现负荷功率在不同储能单元之间的动态分配。该方法中设置传统下垂控制中的下垂系数和储能单元SOC的n次幂呈反比。通过改变SOC的幂指数n,可以实现对SOC及输出功率均衡速率的调整。由于该控制方法基于下垂控制实现,因此会带来直流母线电压跌落。该文引入二次控制方法,以提升母线电压至其额定取值。传统的二次控制针对固定系数的下垂控制进行母线电压跌落补偿,而在改进的下垂控制方法中,下垂系数根据SOC改变,以扰动的形式作用于二次控制系统。该文验证了二次控制对于改进下垂控制方法的适用性,建立了控制结构的整体模型,并根据该模型对控制系统的稳定性进行了验证。利用Ma.la./Simulink进行了仿真验证,并搭建了基于dSPa.E1103的2×2.2 kW样机平台,对所提出的控制结构进行了实验验证。

关键词：直流微电网分布式储能下垂控制剩余容量二次控制

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Redunda.cy Ring Design for Tra.sponder Subsystem in the VX-Sa. Communica.ion Sa.ellite

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Computer a.ded Dra.ting,Design a.d Ma.ufa.turing 2010年第1期20卷 46-55页

作者： guerrero E a.Va.EZ J RIVERO L School of Electronics a.d Informa.ion Engineering Beijing University of Aeronautics and Astronautics

Modem communica.ions is a. indispensa.le tool for modem socia. economy a.d modem socia. life. The pa.loa. of a.communica.ion sa.ellite provides ra.io rela. for links between ea.th sta.ions. With most commercia. communica.ion sa.ellites the pa.loa. consists of two distinct pa.ts with well defined interfa.es： the repea.er a.d the a.tenna.. The repea.er designa.es the electronic equipment which performs a.ra.ge of functions on the signa.s from the receiving a.tenna.before delivering them to the tra.smitting a.tenna. The VX-Sa. project is a.system engineering exercise, rea.ized in the China.a.a.emy of Spa.e Technology （Ca.T） with the objective of tra.ning the persons in cha.ge of designing futures communica.ion sa.ellites in the Boliva.ia. a.ency of Spa.e a.tivities （a.a.） in Venezuela. This pa.er includes a. overview of the VX-Sa. system, the prelimina.y design of the communica.ions pa.loa. a.d fina.ly the method used to design the redunda.cy ring of the tra.sponder subsystem.

关键词： communica.ion sa.ellite pa.loa. Ku-ba.d redunda.cy ring

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