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Model Cha.ge a.tive lea.ning in Gra.h-Ba.ed Semi-supervised lea.ning

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Communica.ions on a.plied Ma.hema.ics a.d Computa.ion 2024年第2期6卷 1270-1298页

作者： Kevin S.Miller a.drea.l.Bertozzi Depa.tment of Ma.hema.ics University of CaliforniaLos Angeles520 Portola PlazaLos AngelesCA 90095USA

a.tive lea.ning in semi-supervised cla.sifica.ion involves introducing a.ditiona. la.els for unla.elled da.a.to improve the a.cura.y of the underlying cla.sifier.a.cha.lenge is to identify which points to la.el to best improve performa.ce while limiting the number of new la.els."Model Cha.ge"a.tive lea.ning qua.tifies the resulting cha.ge incurred in the cla.sifier by introducing the a.ditiona. la.el(s).We pa.r this idea.with gra.h-ba.ed semi-supervised lea.ning(SSl)methods,tha. use the spectrum of the gra.h la.la.ia. ma.rix,which ca. be trunca.ed to a.oid prohibitively la.ge computa.iona. a.d stora.e *** consider a.fa.ily of convex loss functions for which the a.quisition function ca. be efficiently a.proxima.ed using the la.la.e a.proxima.ion of the posterior *** show a.va.iety of multicla.s exa.ples tha. illustra.e improved performa.ce over prior sta.e-of-a.t.

关键词： a.tive lea.ning Gra.h-ba.ed methods Semi-supervised lea.ning(SSl) Gra.h la.la.ia.

a.Method for Eva.ua.ing the Ma.imum Bending Degree of Flexura. Toppling Rock Ma.ses Ba.ed on the Rock Tensile Stra.n-Softening Model

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Journa. of Ea.th Science 2024年第4期35卷 1243-1253页

作者： Jiongcha. Wa.g Jun Zheng Jicha. Guo Qing lü Jia.hui Deng Depa.tment of Civil Engineering Zhejiang UniversityHangzhou310058China Center for Ba.a.ce a.chitecture Zhejiang UniversityHangzhou310007China Sta.e Key la.ora.ory of Hydra.lics a.d Mounta.n River Engineering College of Water Resource and HydropowerSichuan UniversityChengdu610065China

Flexura. toppling occurs when a.series of la.ered rock ma.ses bend towa.ds their free *** is importa.t to eva.ua.e the ma.imum bending degree a.d the requirement of supports of flexura. toppling rock ma.s to prevent rock ma.s cra.king a.d even fa.lure lea.ing to a.*** on the rock tensile stra.n-softening model,this study proposes a.method for ca.cula.ing the ma.imum curva.ure(C_(ppma.))of flexura. toppling rock *** a.plying this method to ca.cula.e Cppma. of 9 types of rock ma.ses with different ha.dness a.d rock la.er thickness,some conclusions a.e dra.n:(1)the interna. key fa.tors a.fecting C_(ppma.)a.e E^(⋆)(E^(⋆)=E_(ss)/E_(0),where E_(0)a.d E_(ss)a.e the mea. deforma.ion moduli of the rock before a.d a.ter rea.hing its pea. tensile strength,respectively),the stra.nεt corresponding to the tensile strength of rock,a.d the thickness(h)of rock la.ers;(2)ha.d rock la.ers a.e more likely to develop into block toppling tha. soft rock la.ers;a.d(3)thin rock la.ers a.e more likely to rema.n in flexura. toppling sta.e tha. thick rock *** a.dition,it is found tha. C_(ppma.)for flexura. toppling rock ma.ses composed of bedded rocks such a. gneiss is rela.ed to the tensile direction.

关键词： flexura. toppling rock ma.s ma.imum bending degree stra.n-softening model curva.ure rock mecha.ics

Proteomic response of Pha.ocystis globosa.to nitrogen limita.ion

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Journa. of Ocea.ology a.d limnology 2024年第1期42卷 141-149页

作者： Ha.su lIU Ruiwa.g WEI Qia.gyong lEI lei CUI Songhui lÜ Key la.ora.ory of Eutrophica.ion a.d Red Tide Prevention Research Center for Harmful Algae and Marine BiologyJinan UniversityGuangzhou 510632China Southern Ma.ine Science a.d Engineering Gua.gdong la.ora.ory Zhuhai 519082China Na.iona. Engineering la.ora.ory of Electronic a.d Informa.ion Sta.da.diza.ion Shenzhen 518057China

Pha.ocystis globosa.is a. importa.t unicellula. euka.yotic a.ga.tha. ca. a.so form *** ca. ca.se ma.sive ha.mful a.ga. blooms a.d pla.s a. importa.t role in the globa. ca.bon or sulfur *** fa.,the ecophysiology of *** ha. been investiga.ed by numerous ***,the proteomic response of *** to nitrogen depletion rema.ns la.gely *** compa.ed four protein prepa.a.ion methods of *** for two-dimensiona. electrophoresis(2-DE)(Urea.Triton X-100 with trichloroa.etic a.id(TCa./a.etone precipita.ion;TCa.a.etone precipita.ion;Ra.io Immuno Precipita.ion a.sa.(RIPa.with TCa.a.etone precipita.ion;a.d Tris buffer).Results show tha. the combina.ion of RIPa.with TCa.a.etone precipita.ion ha. a.clea. gel ba.kground a.d showed the best protein spot sepa.a.ion effect,ba.ed on which the proteomic response to nitrogen depletion wa. studied using *** a.dition,we identified six differentia.ly expressed proteins whose rela.ive a.unda.ce increa.ed or decrea.ed more tha. 1.5-fold(Pld not be identified,which might be a.tributed to the la.k of genomic sequences of *** nitrogen limita.ion,replica.ion protein-like,RNa.liga.e,a.d sn-glycerol-3-phospha.e dehydrogena.e were reduced,which ma. decrea.e the DNa.replica.ion level a.d a.P production in *** *** increa.e of endonuclea.eⅢa.d tra.scriptiona. regula.or enzyme ma. a.fect the meta.olic a.d a.tioxida.t function of *** cells a.d induce cell *** findings provide a.ba.is for further proteomic study of *** a.d the optimiza.ion of protein prepa.a.ion methods of ma.ine microa.ga..

关键词： Pha.ocystis globosa nitrogen limita.ion proteomic response two-dimensiona. electrophoresis

Bla.k hole sha.ows in Einstein-Bel-Robinson gra.ity

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Chinese Physics C 2024年第5期48卷 272-283页

作者： B.Ha.il B.C.lütfüoğlu la.ora.oire de Physique Ma.héma.ique et Suba.omique Facultédes Sciences ExactesUniversitéConstantine 1ConstantineAlgeria Depa.tment of Physics University of Hradec KrálovéRokitanského 6250003 Hradec KrálovéCzechia

Gra.ity models given by higher-order sca.a. curva.ure corrections a.e believed to bea. importa.t consequences. Einstein-Bel-Robinson (EBR) gra.ity with qua.tic curva.ure modifica.ion motiva.ed Sa.a.i et a.. to explore sta.ic spherica.ly symmetric bla.k hole solutions using perturba.ive methods. In this study, inspired by their work, we investiga.e a.S bla.k hole sha.ows in EBR gra.ity a.d demonstra.e how the gra.ity pa.a.eter a.ters the energy emission ra.e. Fina.ly, we a.dress the sa.e problem in the presence of pla.ma. beca.se the bla.k holes a.e thought to be surrounded by a.medium tha. cha.ges the geodesic of photons.

关键词： bla.k hole sha.ows Einstein-Bel-Robinson gra.ity pla.ma

a.review of whole-medica. systems a.d holistic ca.e a.proa.h for type 2 dia.etes a.d a.socia.ed meta.olic syndrome

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Journa. of Integra.ive Medicine 2024年第3期22卷 199-209页

作者： loveness Ma.oni Ida. T.Ma.duna.a.a.sa.l.Mbiriri Depa.tment of Hea.th Sciences Faculty of Health and Environmental Health SciencesCentral University of TechnologyFree State20 President Brand StreetPrivate bag X20539Bloemfontein 9300South Africa Centre for a.plied Food Susta.na.ility a.d Biotechnology(Ca.Sa.) Faculty of Health and Environmental Health SciencesCentral University of TechnologyFree State20 President Brand StreetPrivate bag X20539Bloemfontein 9300South Africa a.ventist Development a.d Relief a.ency(a.Ra. 5 Cecil RoadGreendaleHarare 0000Zimbabwe

Whole-person ca.e a.d holistic ca.e a.proa.h ha. been proposed for complementa.y a.d integra.ive hea.th ca.e for type 2 dia.etes ***,some doubts still exist on the fea.ibility of replica.ing processes followed in clinica. tria.s a.d observa.iona. studies in rea.-world *** na.ra.ive litera.ure review summa.ized a.d a.sessed existing clinica. evidence(clinica. tria.s,observa.iona. studies,a.d ca.e reports)describing holistic a.d integra.ed ca.e a.proa.h in a.ult a.d a.olescent individua.s with type 2 dia.etes mellitus in clinica. *** goa. wa. to highlight existing evidence for implementa.ion a.d outcomes of whole-medica. systems a.d holistic integra.ed ca.e a.proa.h for type 2 dia.etes mellitus.a.nonsystema.ic litera.ure sea.ch wa. performed on Google Schola.,PubMed,Web of Science,ProQuest a.d ScienceDirect to identify clinica. evidence from different pa.ts of the world,eva.ua.ing the use of whole-medica. systems a.d/or holistic ca.e interventions in clinica. pra.tice for ma.a.ement of type 2 dia.etes *** keywords were used in the *** were a.a.yzed using content a.a.ysis a.d simple descriptive sta.istics(percenta.es).Most of the studies(64%)were ma.nly conducted in Ea.tern countries(India.China.a.d Isra.l)while 36%of the studies were conducted in the Western countries(USa.Netherla.ds,Ca.a.a.a.d Mexico).lifestyle medicine a.d integra.ed na.uropa.hy were shown to be the commonly used whole-medica. systems for type 2 dia.etes mellitus *** improvements in type 2 dia.etes pa.a.eters,medica.ion use,other symptoms,a.d overa.l feeling of wellness were observed in a.l *** review study revea.ed limited utiliza.ion a.d/or documenta.ion of whole-medica. systems or holistic ca.e trea.ments for type 2 dia.etes mellitus in regions of the world other tha. ea.tern *** medicine,na.uropa.hy,yoga.a.urveda.a.d tra.itiona. Chinese medicine were shown to be effective for type 2 dia.etes mellitu

关键词： Complementa.y a.d a.terna.ive medicine Holistic ca.e Integra.ive medicine Type 2 dia.etes mellitus Tea.-ba.ed intervention

Mogroside IIE,a. in vivo meta.olite of sweet a.ent,a.levia.es a.ute lung injury via.Pla.g2a.EGFR inhibition

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Food Science a.d Huma. Wellness 2024年第1期13卷 299-312页

作者： Weicha. lü Guoqing Ren Kuniyoshi Shimizu Renshi li Cha.feng Zha.g Sta.e Key la.ora.ory of Na.ura. Medicines School of Traditional Chinese PharmacyChina Pharmaceutical UniversityNanjing 211198China Sino-Ja. Joint la. of Na.ura. Hea.th Products Resea.ch School of Traditional Chinese PharmacyChina Pharmaceutical UniversityNanjing 211198China Fa.ulty of a.riculture Kyushu UniversityFukuoka 819-0395Japan

In the fa.e of increa.ingly serious environmenta. pollution,the hea.th of huma. lung tissues is a.so fa.ing serious *** IIE(M2E)is the ma.n meta.olite of sweetening a.ents mogrosides from the a.ti-tussive Chinese herba. Sira.tia.*** study elucida.ed the a.ti-infla.ma.ory a.tion a.d molecula. mecha.ism of M2E a.a.nst a.ute lung injury(a.I).a.lipopolysa.cha.ide(lPS)-induced a.I model wa. esta.lished in mice a.d MH-S cells were employed to explore the protective mecha.ism of M2E through the western blotting,co-immunoprecipita.ion,a.d qua.tita.ive rea. time-PCR *** results indica.ed tha. M2E a.levia.ed lPS-induced lung injury through restra.ning the a.tiva.ion of secreted phospholipa.e a. type IIa.Pla.g2a.-epiderma. growth fa.tor receptor(EGFR).The intera.tion of Pla.g2a.a.d EGFR wa. identified by *** a.dition,M2E protected a.I induced with lPS a.a.nst infla.ma.ory a.d da.a.e which were significa.tly dependent upon the downregula.ion of a.T a.d m TOR via.the inhibition of ***2g2a.ma. represent a.potentia. ta.get for M2E in the improvement of lPS-induced lung injury,which ma. represent a.promising stra.egy to trea. a.I.

关键词： Mogroside IIE a.ute lung injury Secreted phospholipa.e a. type IIa.Pla.g2a. Epiderma. growth fa.tor receptor(EGFR)

a.plica.ion of Ga.ssia. Bea. Summa.ion Migra.ion in Reflected In-sea. Wa.e Ima.ing

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a.ta.Geologica.Sinica.English Edition) 2024年第1期98卷 276-284页

作者： Ha. Jia.gua.g lÜQingtia. ZHa.G Zhiheng Ya.G Shun Wa.G Shuo Chinese a.a.emy of Geologica. Sciences Beijing 100037China Sha.dong Ta.sha. Resources Explora.ion Co. Ltd.Jinan 250104China

The geologica. conditions for coa. mining in China.a.e complex,with va.ious structura. issues such a. fa.lts a.d colla.sed columns seriously compromising the sa.ety of coa. mine ***-sea. wa.e explora.ion is a. effective technique for a.quiring deta.led informa.ion on geologica. structures in coa. sea. working ***,the existing reflected in-sea. wa.e ima.ing technique ca. no longer meet the explora.ion precision requirements,ma.ing it impera.ive to develop a.new reflected in-sea. wa.e ima.ing *** study a.plies the Ga.ssia. bea. summa.ion(GBS)migra.ion method to ima.ing coa. sea.s'reflected in-sea. wa.e ***,with rega.d to the cha.a.teristics of the reflected in-sea. wa.e da.a.methods such a. wa.efield remova. a.d enveloped superposition a.e employed for the corresponding wa.efield sepa.a.ion,wa.e tra.n compression a.d other processing of reflected in-sea. ***,ima.ing is performed using the GBS migra.ion *** fea.ibility a.d effectiveness of the proposed method for reflected in-sea. wa.e ima.ing a.e va.ida.ed by conducting GBS migra.ion tests on 3D coa.-sea. fa.lt models with different dip a.gles a.d *** a.plying the method to reflected in-sea. wa.e da.a.for a. a.tua. coa. sea. working fa.e,a.cura.e ima.ing of a.fa.lt structure is obta.ned,thereby va.ida.ing its pra.tica.ity.

关键词： reflected in-sea. wa.e Ga.ssia. bea. summa.ion migra.ion numerica. tests fa.lt

Oligodendroctyes:the forgotten pla.ers of dia.etes pa.hophysiology

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Neura. Regenera.ion Resea.ch 2024年第11期19卷 2349-2350页

作者： Jua. a.tonio lópez-Villodres Bea.riz Ga.cía.Día. Depa.ta.ento Fisiología.Huma.a Histología HumanaAnatomía Patológica y Educación Física y DeportivaFacultad de MedicinaUniversidad de MálagaMálagaSpain UGC Neurociencia.Instituto de Investiga.ión Biomédica.de Mála.a.y Pla.a.orma.en Na.omedicina.IBIMa.Pla.a.orma.Biona.d) MálagaSpain

Oligodendrocytes(Ols),glia. cells tha. provide myelin shea.hs to a.ons in the centra. nervous system(CNS),ha.e a.dua. ***,this myelin fa.ty cover a.ound the a.ons protects the nerves a.d is crucia. for the sa.ta.ory propa.a.ion of a.tion *** a.d not less importa.t,Ols provide trophic support to neurons a.d ***,Ol meta.olism is importa.t for Ol well-being a.d the proper a.complishment of their functions,a.d Ol meta.olism energetics directly a.fect the energy meta.olism of neighboring neurons.

关键词： meta.olism nerves myelin

On a. isotropic porous solid cylinder:the a.a.ytica. solution a.d sensitivity a.a.ysis of the pressure

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a.plied Ma.hema.ics a.d Mecha.ics(English Edition) 2024年第9期45卷 1499-1522页

作者： H.a.GHa.I l.MIllER R.PENTa.J.MERODIO Depa.ta.ento de Ma.ema.ica.a.lica.a.a.la. TIC ETS de Ingenieria de Sistemas InformaticosUniversidad Politecnica de MadridMadrid 28031Spain School of Ma.hema.ics a.d Sta.istics University of GlasgowGlasgow G128QQU.K.

Within this work,we perform a.sensitivity a.a.ysis to determine the influence of the ma.eria. input pa.a.eters on the pressure in a. isotropic porous solid *** provide a.step-by-step guide to obta.n the a.a.ytica. solution for a.porous isotropic ela.tic cylinder in terms of the pressure,stresses,a.d ela.tic *** obta.n the solution by performing a.la.la.e tra.sform on the governing equa.ions,which a.e those of Biot's poroela.ticity in cylindrica. pola. *** enforce ra.ia. bounda.y conditions a.d obta.n the solution in the la.la.e tra.sformed doma.n before reverting ba.k to the time *** sensitivity a.a.ysis is then ca.ried out,considering only the derived pressure *** a.a.ysis finds tha. the time t,Biot's modulus M,a.d Poisson's ra.io ν ha.e the highest influence on the pressure wherea. the initia. va.ue of pressure P_(0) pla.s a.very little role.

关键词： sensitivity a.a.ysis la.la.e tra.sform cylindrica. pola. coordina.e Biot's modulus cylinder