检索结果-南通市图书馆

Beyond wrecking a.wa.l:revisiting the concept of blood–bra.n ba.rier brea.down in ischemic stroke

Neura. Regenera.ion Resea.ch 2025年第7期20卷 1944-1956页

作者： Julia.Ca.tillo-gonzále. Ele.a.gonzále.-Rey Institute of Pa.a.itology a.d Biomedicine Lopez-Neyra.IPBLN) CSICPT SaludGranadaSpain

The blood–bra.n ba.rier constitutes a.dyna.ic a.d intera.tive bounda.y sepa.a.ing the centra. nervous system a.d the periphera. *** tightly modula.es the ion tra.sport a.d nutrient influx,while.restricting the entry of ha.mful fa.tors,a.d sele.tively limiting the migra.ion of immune cells,thereby ma.nta.ning bra.n *** the well-esta.lished a.socia.ion between blood–bra.n ba.rier disruption a.d most neurodegenera.ive/neuroinfla.ma.ory disea.es,much rema.ns unknown a.out the fa.tors influencing its physiology a.d the mecha.isms underlying its ***,the role.of blood–bra.n ba.rier brea.down in the tra.sla.iona. fa.lure underlying thera.ies for bra.n disorders is just sta.ting to be *** review a.ms to revisit this concept of“blood–bra.n ba.rier brea.down,”delving into the most controversia. a.pects,preva.0}t cha.le.ges,a.d knowle.ge ga.s concerning the la.k of blood–bra.n ba.rier *** moving beyond the oversimplistic dichotomy of a.“open”/“ba.”or a.closed”/“good”ba.rier,our objective is to provide a.more comprehensive insight into blood–bra.n ba.rier dyna.ics,to identify novel ta.gets a.d/or thera.eutic a.proa.hes a.med a. mitiga.ing blood–bra.n ba.rier ***,in this review,we a.voca.e for considering the diverse time-a.d loca.ion-dependent a.tera.ions in the blood–bra.n ba.rier,which go beyond tight-junction disruption or bra.n endothelia. cell brea.down,illustra.ed through the dyna.ics of ischemic stroke a. a.ca.e *** this explora.ion,we seek to underscore the comple.ity of blood–bra.n ba.rier dysfunction a.d its implica.ions for the pa.hogenesis a.d thera.y of bra.n disea.es.

关键词： blood–bra.n ba.rier disruption drug delivery ischemic stroke neuroinfla.ma.ion tight-junctions

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Impa.ts of PI3K/protein kina.e B pa.hwa. a.tiva.ion in rea.tive a.trocytes: from detrimenta. effects to protective functions

引用

Neura. Regenera.ion Resea.ch 2025年第4期20卷 1031-1041页

作者： Ra.ón Pérez-Núñez Ma.ía.Ferna.da.gonzále. a.a.Ma.ía.a.a.os Lisette le.ton Cellula. Communica.ion La.ora.ory Programa de Biología Celular y MolecularCenter for Studies on ExerciseMetabolism and Cancer(CEMC)Instituto de Ciencias Biomédicas(ICBM)Facultad de MedicinaUniversidad de ChileSantiagoChile a.va.ced Center for Chronic Disea.es(a.CDiS) Faculty of Chemical and Pharmaceutical Sciences&Faculty of MedicineUniversidad de ChileSantiagoChile Instituto de Ciencia. Biomédica. Facultad de Ciencias de la SaludUniversidad Autónoma de ChileSantiagoChile

a.trocytes a.e the most a.unda.t type of glia. cell in the centra. nervous *** injury a.d infla.ma.ion,a.trocytes become rea.tive a.d undergo morphologica. a.d functiona. *** on their phenotypic cla.sifica.ion a. a. or a.,rea.tive a.trocytes contribute to both neurotoxic a.d neuroprotective responses,***,this bina.y cla.sifica.ion does not fully ca.ture the diversity of a.trocyte responses observed a.ross different disea.es a.d *** a.a.ysis ha. revea.0} tha. rea.tive a.trocytes ha.e a.comple. la.dsca.e of gene expression profile.,which empha.izes the heterogeneous na.ure of their *** a.tively pa.ticipa.e in regula.ing centra. nervous system infla.ma.ion by intera.ting with microglia.a.d other cell types,rele.sing cytokines,a.d influencing the immune *** phosphoinositide 3-kina.e(PI3K)/protein kina.e B(a.T)signa.ing pa.hwa. is a.centra. pla.er in a.trocyte rea.tivity a.d impa.ts va.ious a.pects of a.trocyte beha.ior,a. evidenced by in silico,in vitro,a.d in vivo *** a.trocytes,infla.ma.ory cues trigger a.ca.ca.e of mole.ula. events,where nucle.r fa.tor-κB serves a. a.centra. media.or of the pro-infla.ma.ory ***,we review the heterogeneity of rea.tive a.trocytes a.d the mole.ula. mecha.isms underlying their *** highlight the involvement of va.ious signa.ing pa.hwa.s tha. regula.e a.trocyte rea.tivity,including the PI3K/a.T/ma.ma.ia. ta.get of ra.a.ycin(mTOR),αvβ3 integrin/PI3K/a.T/connexin 43,a.d Notch/PI3K/a.T *** ta.geting the ina.tiva.ion of the PI3K/a.T cellula. signa.ing pa.hwa. to control rea.tive a.trocytes a.d prevent centra. nervous system da.a.e,evidence suggests tha. a.tiva.ing this pa.hwa. could a.so yield beneficia. *** dua. function of the PI3K/a.T pa.hwa. underscores its comple.ity in a.trocyte rea.tivity a.d bra.n function *** review empha.izes the importa.ce of employing a.trocyte-exclusive models to underst

关键词： infla.ma.ion integrins neuroprotective neurotoxic phospha.idylinositol 3-kina.e rea.tive a.trocytes signa. tra.sduction Thy-1(CD90)

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Microglia.la.tyla.ion in rela.ion to centra. nervous system disea.es

引用

Neura. Regenera.ion Resea.ch 2025年第1期20卷 29-40页

作者： Hui Ya.g Na. Mo le.Tong Jia.hong Dong Ziwei Fa. mengxia. Jia.Jua.qing Yue Ying Wa.g School of Pha.ma.y Hangzhou Normal UniversityHangzhouZhejiang ProvinceChina Depa.tment of Clinica. La.ora.ory The Fourth Clinical Medical College of Zhejiang University of Traditional Chinese Medicine(Hangzhou First People’s Hospital)HangzhouZhejiang ProvinceChina Colle.e of medica. Veterinary and Life SciencesUniversity of GlasgowGlasgowUK Depa.tment of Orthopedics(Spine Surgery) the First Affiliated Hospital of Wenzhou Medical UniversityWenzhouZhejiang ProvinceChina Depa.tment of Pa.hology Affiliated Hangzhou First People’s HospitalWestlake University School of MedicineHangzhouZhejiang ProvinceChina Depa.tment of Clinica. Resea.ch Center Affiliated Hangzhou First People’s HospitalWestlake University School of MedicineHangzhouZhejiang ProvinceChina

The development of neurodegenera.ive disea.es is closely rela.ed to the disruption of centra. nervous system ***,a. inna.e immune cells,pla. importa.t role. in the ma.ntena.ce of centra. nervous system homeosta.is,injury response,a.d neurodegenera.ive *** ha. been considered a.meta.olic wa.te product,but recent studies a.e revea.ing ever more of the physiologica. functions of *** is a. importa.t pa.hwa. in la.ta.e function a.d is involved in glycolysis-rela.ed functions,ma.ropha.e pola.iza.ion,neuromodula.ion,a.d a.giogenesis a.d ha. a.so been implica.ed in the development of va.ious *** review provides a. overview of the la.ta.e meta.olic a.d homeosta.ic regula.ory processes involved in microglia.la.tyla.ion,histone versus non-histone la.tyla.ion,a.d thera.eutic a.proa.hes ta.geting ***,we summa.ize the current resea.ch on microglia.la.tyla.ion in centra. nervous system disea.es.a.deeper understa.ding of the meta.olic regula.ory mecha.isms of microglia.la.tyla.ion will provide more options for the trea.ment of centra. nervous system disea.es.

关键词： bra.n centra. nervous system glycolysis immune response infla.ma.ion la.ta.e meta.olism la.ta.e la.tyla.ion microglia neurodegenera.ive disea.es

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Free vibra.ion a.d tra.sient response of double.curved bea.s connected by intermedia.e stra.ght bea.s

引用

a.plied Ma.hema.ics a.d mecha.ics(English Edition) 2025年第1期46卷 37-62页

作者： R.a.Ja.a.I-Ta.OOKOLa.I H.GHa.DVa. E.JUMa.V S.KHa.IR T.CUONG-le School of mecha.ica. Engineering Babol Noshirvani University of Technology Depa.tment of mecha.ica. Engineering Faculty of Engineering New Uzbekistan University University of Business a.d Science Center for Engineering a.plica.ion a.d Technology Solutions Ho Chi Minh City Open University

This pa.er investiga.es the free vibra.ion a.d tra.sient response of interconnected structures including double.curved bea.s a.d intermedia.e stra.ght bea.s,which a.e a.l constructed from functiona.ly gra.ed porous(FGP) ma.eria.s. The stra.n potentia. a.d kinetic energies of ea.h bea. a.ong with the work done by the externa. force a.e ca.cula.ed. a.ditiona.ly, a.higher-order bea. ele.ent is introduced to derive stiffness a.d ma.s ma.rices, a.ong with the force vector. The curved a.d stra.ght bea.s a.e discretized, a.d their a.semble. stiffness, ma.s ma.rices, a.d force vectors, a.e *** conditions a. the joints a.e used to derive the tota. ma.rices of the entire structure. Subsequently, the na.ura. frequencies a.d tra.sient response of the system a.e determined. The a.cura.y of the ma.hema.ica. model a.d the self-developed computer progra. is va.ida.ed through the compa.ison of the obta.ned results with those of the existing litera.ure a.d commercia. softwa.e a.SYS, demonstra.ing excelle.t ***, a.comprehensive study is conducted to investiga.e the effects of va.ious pa.a.eters on the free vibra.ion a.d tra.sient response of the considered structure.

关键词：

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Mutua. regula.ion of microglia.a.d a.trocytes a.ter Ga.6 inhibits spina. cord injury

引用

Neura. Regenera.ion Resea.ch 2025年第2期20卷 557-573页

作者： Jiewen Chen Xia.lin Zeng le.Wa.g Wenwu Zha.g Ga.g Li Xing Cheng Peiqia.g Su Yong Wa. Xia.g Li Depa.tment of Spine Surgery The First Affiliated HospitalSun Yat-sen UniversityGuangzhouGuangdong ProvinceChina Gua.gdong Province Key La.ora.ory of Orthopedics a.d Tra.ma.ology GuangzhouGuangdong ProvinceChina

Inva.ive infla.ma.ion a.d excessive sca. forma.ion a.e the ma.n rea.ons for the difficulty in repa.ring nervous tissue a.ter spina. cord *** a.d a.trocytes pla. key role. in the spina. cord injury micro-environment a.d sha.e a.close ***,the mecha.isms involved rema.n *** this study,we found tha. a.ter spina. cord injury,resting microglia.M0)were pola.ized into pro-infla.ma.ory phenotypes(MG1 a.d MG3),while.resting a.trocytes were pola.ized into rea.tive a.d sca.-forming *** expression of growth a.rest-specific 6(Ga.6)a.d its receptor a.l were significa.tly down-regula.ed in microglia.a.d a.trocytes a.ter spina. cord *** vitro experiments showed tha. Ga.6 ha. nega.ive effects on the pola.iza.ion of rea.tive a.trocytes a.d pro-infla.ma.ory microglia.a.d even inhibited the cross-regula.ion between *** further demonstra.ed tha. Ga.6 ca. inhibit the pola.iza.ion of rea.tive a.trocytes by suppressing the a.tiva.ion of the Yes-a.socia.ed protein signa.ing ***,in turn,inhibited the pola.iza.ion of pro-infla.ma.ory microglia.by suppressing the a.tiva.ion of the nucle.r fa.tor-κB/p65 a.d Ja.us kina.e/signa. tra.sducer a.d a.tiva.or of tra.scription signa.ing *** vivo experiments showed tha. Ga.6 inhibited the pola.iza.ion of pro-infla.ma.ory microglia.a.d rea.tive a.trocytes in the injured spina. cord,thereby promoting tissue repa.r a.d motor function ***,Ga.6 ma. pla. a.role.in the trea.ment of spina. cord *** ca. inhibit the infla.ma.ory pa.hwa. of microglia.a.d pola.iza.ion of a.trocytes,a.tenua.e the intera.tion between microglia.a.d a.trocytes in the infla.ma.ory microenvironment,a.d thereby a.le.ia.e loca. infla.ma.ion a.d reduce sca. forma.ion in the spina. cord.

关键词： a.trocytes a.l cell pola.iza.ion Ga.6 Hippo signa. infla.ma.ory micro-environment intercellula. intera.tion microglia single.cell sequencing spina. cord injury

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Distributed a.gorithms for Event Reporting in Mobile.Sink WSNs for Internet of Things

引用

Tsinghua.Science a.d Technology 2017年第4期22卷 413-426页

作者： catalina a.a.za.u-Suescun Miha.la.Ca.dei Depa.tment of Computer a.d Ele.trica. Engineering a.d Computer Science Florida Atlantic University

Wirele.s Sensor Networks（WSNs） ha.e ma.y a.plica.ions, such a. clima.e monitoring systems, fire detection, sma.t homes, a.d sma.t cities. It is expected tha. WSNs will be integra.ed into the Internet of Things（IoT）a.d pa.ticipa.e in va.ious ta.ks. WSNs pla. a. importa.t role.monitoring a.d reporting environment informa.ion a.d colle.ting surrounding context. In this pa.er we consider a.WSN deployed for a. a.plica.ion such a. environment monitoring, a.d a.mobile.sink which a.ts a. the ga.ewa. between the Internet a.d the WSN. Da.a.ga.hering is a.cha.le.ging proble. in WSNs a.d in the IoT beca.se the informa.ion ha. to be a.a.la.le.quickly a.d effectively without dela.s a.d redunda.cies. In this pa.er we propose severa. distributed a.gorithms for composite event detection a.d reporting to a.mobile.sink. Once da.a.is colle.ted by the sink, it ca. be sha.ed using the IoT infra.tructure. We a.a.yze the performa.ce of our a.gorithms using WSNet simula.or, which is specia.ly designed for event-ba.ed WSNs. We mea.ure va.ious metrics such a. a.era.e residua. energy, percenta.e of composite events processed successfully a. the sink, a.d the a.era.e number of hops to rea.h the sink.

关键词： composite events distributed a.gorithm energy efficiency event-ba.ed clustering Internet of Things mobile.sink wirele.s sensor networks

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Spa.io-Tempora. evolutive Da.a.Infra.tructure: a.Spa.ia. Da.a.Infra.tructure for ma.a.ing da.a.flows of Territoria. Sta.istica. Informa.ion

引用

Interna.iona. Journa. of Digita. Ea.th 2017年第3期10卷 257-283页

作者： Ca.ille.Berna.d Ma.lène Villa.ova.Oliver Jérôme Gensel Benoit le.Rubrus Univ.Grenoble.a.pes CNRSLIGGrenobleFrance

The observa.ion of demogra.hica.,economica. or environmenta. indica.ors over time through ma.s is *** ena.le. a.a.ysing territories a.d helps sta.eholders to ta.e ***,the understa.ding of Territoria. Sta.istica. Informa.ion(TSI)is compromised unle.s comprehensive description of both the sta.istica. methodology used a.d the spa.ia. a.d tempora. references a.e ***,in this pa.er,we stress the importa.ce of meta.a.a.descriptions a.d of their qua.ity tha. helps a.sessing da.a.***,time-series of such TSI a.e *** ena.le.a.a.ysing a.territory over a.long period of time a.d likewise judging the effectiveness of *** light of these observa.ions,we present Spa.io-Tempora. evolutive Da.a.Infra.tructure(STeDI)a. innova.ive Spa.ia. Da.a.Infra.tructure(SDI)tha. enriches the description of a.Digita. Ea.th,providing a.virtua. representa.ion of territories a.d of their evolution through sta.istics a.d *** a.ms a. ma.a.ing a.whole.da.a.low of multi-dimensiona.,multi-sca.0}a.d multi-tempora. TSI,from their a.quisition to their dissemina.ion to scientists a.d *** content of this SDI evolves a.tonomously tha.ks to a.toma.ed processes a.d to a.Web pla.form tha. help improving the qua.ity of da.a.ets uploa.ed by ***,STeDI a.lows visua.izing up-to-da.e time-series refle.ting the huma. a.tivities on a.given *** helps policy-ma.ers in their decision-ma.ing process.

关键词： Spa.ia. Da.a.Infra.tructure Territoria. Sta.istica. Informa.ion meta.a.a da.a.qua.ity INSPIRE

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

a.toregressive neura. networks with exogenous va.ia.le. for indoor tempera.ure prediction in buildings

引用

Building Simula.ion 2021年第1期14卷 165-178页

作者： Benoit Delcroix Jérôme le.Ny Michel Bernier Muha.ma. a.a. Bingrui Qu Jea.-Simon Venne Depa.tment of mecha.ica. Engineering Polytechnique Montréal2500 Chemin de PolytechniqueMontréalQCH3T 1J4Canada Depa.tment of Ele.trica. Engineering a.d GERa. Polytechnique Montréal2500 Chemin de PolytechniqueMontréalQCH3T 1J4Canada Sma.t Building La. BrainBox AIMontréalQCCanada

Therma. models of buildings a.e helpful to foreca.t their energy use a.d to enha.ce the control of their mecha.ica. ***,these models a.e building-specific a.d require a.tedious,error-prone a.d time-consuming development effort relying on skille. building energy *** to white-box a.d gra.-box models,da.a.driven(bla.k-box)models require le.s development time a.d a.minima. a.ount of informa.ion a.out the building *** this pa.er,a.toregressive neura. network models a.e compa.ed to gra.-box a.d bla.k-box linea. models to simula.e indoor *** models a.e tra.ned,va.ida.ed a.d compa.ed to a.tua. experimenta. da.a.obta.ned for a. existing commercia. building in Montrea.(QC,Ca.a.a.equipped with roof top units for a.r *** show tha. neura. networks mimic more a.cura.ely the therma. beha.ior of the building when limited informa.ion is a.a.la.le.compa.ed to gra.-box a.d bla.k-box linea. *** gra.-box model does not perform a.equa.ely due to its under-pa.a.eterized na.ure,while.the linea. models ca.not ca.ture non-linea. phenomena.such a. ra.ia.ive hea. tra.sfer a.d ***,the neura. network models outperform the a.terna.ive models in the presented a.plica.ion,rea.hing a.coefficient of determina.ion R2 up to 0.824 a.d a.root mea. squa.e error down to 1.11℃,including the error propa.a.ion over time for a.1-week period with a.5-minute *** considering a.50-hour time horizon,the best neura. networks rea.h a.much lower root mea. squa.e error of a.ound 0.6℃,which is suita.le.for a.plica.ions such a. model predictive control.

关键词： therma. model building simula.ion experimenta. va.ida.ion multi-la.er perceptron linea. vs.non-linea. bla.k-box vs.gra.-box

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Prediction of Shea. Bond Strength of a.pha.t Concrete Pa.ement Using Ma.hine le.rning Models a.d Grid Sea.ch Optimiza.ion Technique

引用

Computer Modeling in Engineering & Sciences 2025年第1期142卷 691-712页

作者： Quynh-a.h Thi Bui Da. Duc Nguyen Hiep Va. le.Indra.Pra.a.h Binh Tha. Pha. Civil Engineering Depa.tment University of Transport Technology54 Trieu KhucThanh XuanHanoi100000Vietnam DDG(R)Geologica. Survey of India Gandhinagar382010India

Determina.ion of Shea. Bond strength(SBS)a. interla.er of double.la.er a.pha.t concrete is crucia. in fle.ible.pa.ement *** study used three Ma.hine le.rning(ML)models,including K-Nea.est Neighbors(KNN),Extra.Trees(ET),a.d Light Gra.ient Boosting Ma.hine(LGBM),to predict SBS ba.ed on ea.ily determina.le.input ***,the Grid Sea.ch technique wa. employed for hyper-pa.a.eter tuning of the ML models,a.d cross-va.ida.ion a.d le.rning curve a.a.ysis were used for tra.ning the *** models were built on a.da.a.a.e of 240 experimenta. results a.d three input va.ia.le.:tempera.ure,norma. pressure,a.d ta.k coa. *** va.ida.ion wa. performed using three sta.istica. criteria.the coefficient of determina.ion(R2),the Root mea. Squa.e Error(RMSE),a.d the mea. a.solute error(Ma.).a.ditiona.ly,SHa. a.a.ysis wa. a.so used to va.ida.e the importa.ce of the input va.ia.le. in the prediction of the *** show tha. these models a.cura.ely predict SBS,with LGBM providing outsta.ding ***(Sha.le. a.ditive expla.a.ion)a.a.ysis for LGBM indica.es tha. tempera.ure is the most influentia. fa.tor on ***,the proposed ML models ca. quickly a.d a.cura.ely predict SBS between two la.ers of a.pha.t concrete,serving pra.tica. a.plica.ions in fle.ible.pa.ement structure design.

关键词： Shea. bond a.pha.t pa.ement grid sea.ch optimiza.ion ma.hine le.rning

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Ma.imum Pa.h Informa.ion a.d Fokker-Pla.ck Equa.ion

引用

Chinese Physics le.ters 2008年第4期25卷 1165-1167页

作者：李炜 Q. a. Wa.g a. le.meha.te Comple.ity Science Center a.d Institute of Pa.ticle.Physics Huazhong Normal University Wuhan 430079 Institut Superieur des Ma.eia.x du Ma.s 44 Avenue F.A. Bartholdi 72000 Le Mans France

We present a.rigorous method to derive the nonlinea. Fokker-Pla.ck （FP） equa.ion of a.oma.ous diffusion directly from a.genera.iza.ion of the principle.of le.st a.tion of Ma.pertuis proposed by Wa.g [Cha.s, Solitons ＆ Fra.ta.s 23 （2005） 1253] for smooth or qua.i-smooth irregula. dyna.ics evolving in Ma.kovia. process. The FP equa.ion obta.ned ma. ta.e two different but equiva.0}t forms. It wa. a.so found tha. the diffusion consta.t ma. depend on both q （the index of Tsa.lis entropy [J. Sta.. Phys. 52 （1988） 479] a.d the time t.

关键词： Ma.HEMa.ICa.-THEORY COMMUNICa.ION DYNa.ICS

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：