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Improvement in Pa.ient Mobility Following Short-Term Reha.ilita.ion in Skilled Nursing Fa.ilities

Open Journa. of Thera.y a.d Reha.ilita.ion 2024年第1期12卷 52-60页

作者： Sea. R. Silver Ja.en a. Silver Sa.ueli School of Engineering University of California Los Angeles USA

Ba.kground: Mobility in older a.ults ca. be impa.red a.ter a.ute illness or hospita.iza.ion, a.d the level of severity ca. be used a. a.predictor of one’s a.ility to return to independent living. Pa.ients a.e often referred to skilled nursing fa.ilities in hopes of improving their mobility. We wa.ted to prove tha. reha.ilita.ive services a. Skilled Nursing Fa.ilities improve overa.l outcomes. Methods: We conducted a.retrospective a.a.ysis of da.a.from 4612 pa.ients a.mitted for short-term reha.ilita.ion in a.la.ge nursing home cha.n in Ca.ifornia. Our a.m wa. to determine whether pa.ients’ mobility scores, a. mea.ured by reha.ilita.ive sta.f, significa.tly improved by time of discha.ge compa.ed to their scores a. a.mission. Mobility scores were ra.ed from 1 to 6, with 1 being the most dependent on a.d a.d 6 being the most independent, over a.va.iety of ta.ks a. a.mission a.d compa.ed to scores a. discha.ge. Pea.son’s correla.ions were performed to determine if there were significa.t rela.ionships in the da.a. the Pea.son’s correla.ion coefficient wa. used to describe the rela.ionships between pa.ient a.mission to a.skilled nursing fa.ility a.d medica. improvement upon discha.ge. Results: The study demonstra.ed a.sta.istica.ly significa.t improvement in pa.ients’ mobility scores upon discha.ge, with Medica.e insured pa.ients showing on a.era.e 57% improvement a.d Ma.a.ed Ca.e insured pa.ients showing on a.era.e 59% improvement. a.ditiona.ly, a.mission scores a.pea.ed to be predictive of the pa.ient’s outcome a. discha.ge. Conclusions: The va.ues a.d consistency of improvement support the use of a.ute reha.ilita.ive services in skilled nursing fa.ilities. a. equa.ion ca. be formula.ed tha. eva.ua.es pa.ients’ estima.ed mobility sta.uses upon discha.ge from fa.ilities ba.ed on their conditions on their a.riva.s. With this, new interventions ca. be studied a.d compa.ed to the current sta.da.d of ca.e by using these mea.urements. They ca. determine if further improvement

关键词： Mobility Skilled Nursing Fa.ility Reha.ilita.ive Services Independent Living Hea.thca.e

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Exploring the Implica.ions of the Deforma.ion Pa.a.eter a.d Minima. Length in the Genera.ized Uncerta.nty Principle

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Journa. of Qua.tum Informa.ion Science 2024年第1期14卷 1-14页

作者： Ma.goub a. Sa.ih Ta.sir M. Elma.di Depa.tment of Physics Faculty of Science and Arts in Al-Miznab Qassim University Al Miznab Saudi Arabia

The brea.down of the Heisenberg Uncerta.nty Principle occurs when energies a.proa.h the Pla.ck sca.e, a.d the corresponding Schwa.zschild ra.ius becomes simila. to the Compton wa.elength. Both of these qua.tities a.e a.proxima.ely equa. to the Pla.ck length. In this context, we ha.e introduced a.model tha. utilizes a.combina.ion of Schwa.zschild’s ra.ius a.d Compton length to qua.tify the gra.ita.iona. length of a. object. This model ha. provided a.novel perspective in genera.izing the uncerta.nty principle. Furthermore, it ha. elucida.ed the significa.ce of the deforming linea. pa.a.eter β a.d its ra.ge of va.ia.ion from unity to its ma.imum va.ue.

关键词： Genera.ized Uncerta.nty Principle Deformed Heisenberg a.gebra Minima. Length

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Expa.ding the Use of Nipple-Spa.ing Ma.tectomies in Obese Pa.ients Undergoing Sta.ed Impla.t-Ba.ed Reconstruction

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Modern Pla.tic Surgery 2024年第3期14卷 23-35页

作者： Ma.lory a. Rowley Pra.ha.t K. Upa.hyaya College of Medicine SUNY Upstate Medical University Syracuse USA Depa.tment of Surgery SUNY Upstate Medical University Syracuse USA

Ba.kground: a.va.ta.es of va.ious ma.tectomy techniques include skin reduction a.d fa.ora.le a.sthetics in Wise-pa.tern closures, a.d less visible sca.s in nipple-spa.ing ma.tectomies (NSM). This study compa.es postopera.ive complica.ion profiles between Wise-pa.tern a.d nipple-spa.ing ma.tectomies in the obese popula.ion. Methods: a.retrospective cha.t review of obese pa.ients (BMI ≥ 30) who underwent sta.ed brea.t reconstruction following Wise-pa.tern a.d nipple-spa.ing ma.tectomies a. our institution between Februa.y 2016 a.d Ja.ua.y 2020 wa. conducted. Complica.ions between cohorts were a.a.yzed using the independent sa.ples t-test (2-sided) a.d the χ2 test. Results: a.tota. of 232 brea.ts (163 Wise-pa.tern, 69 NSM) were re-constructed in 123 obese fema.e pa.ients (85 Wise-pa.tern, 38 NSM). Complica.ion ra.es in both the Wise-pa.tern a.d NSM pa.ient cohorts were simila. following sta.e 1 (Wise-pa.tern: 30.7%, NSM: 39.1%, p = 0.212) a.d sta.e 2 (Wise-pa.tern: 16.6%, NSM: 15.9%, p = 0.907) of reconstruction. No sta.istica.ly significa.t differences in ra.es of infection, dehiscence, seroma. hema.oma.or ma.position of tissue expa.der (TE)/impla.t following sta.e 1 or sta.e 2 were found between cohorts. Conclusions: There were no significa.t differences in postopera.ive complica.ion ra.es between the Wise-pa.tern a.d NSM cohorts of obese pa.ients. NSM ca. be a.via.le surgica. option in ca.efully selected obese pa.ients a.d offer the a.va.ta.e of concea.ed sca.ring.

关键词： Ma.tectomy Brea.t Reconstruction Nipple-Spa.ing

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Tempera.ure Drop of Molten Meta.s in Open Cha.nels

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World Journa. of Engineering a.d Technology 2024年第3期12卷 493-500页

作者： Miguel a. Ba.ron-Meza.Joa. Reyes-Mira.da Depa.ta.ento de Ma.eria.es Universidad Autonoma Metropolitana Azcapotzalco Ciudad de Mexico Mexico

The tempera.ure drop of molten meta. flowing in open cha.nels is numerica.ly determined. Recta.gula., tra.ezoida. a.d tria.gula. geometries a.e considered. The overa.l hea. tra.sfer coefficients for the bottom, side wa.ls a.d free surfa.e of the cha.nel ha.e been ta.en from the litera.ure. For ea.h geometry, the volumetric flow ra.e, mea. residence time a.d tempera.ure drop a. a.function of the cha.nel inclina.ion a.gle were determined. The recta.gula. a.d tra.ezoida. geometries present the sma.lest tempera.ure drops, while the tria.gula. geometry presents the grea.est tempera.ure drop. The fa.tors tha. most a.fect this drop a.e the va.ue of the free surfa.e a.ea.of the cha.nel, a.d the a.era.e residence time of the molten meta. in the cha.nel.

关键词： Free Surfa.e Hea. Tra.sfer Molten Meta. Open Cha.nel Geometry Residence Time Tempera.ure Drop

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Va.ida.ion of a.Method for Cha.a.teriza.ion of Etha.ol in Wa.er by HS-GC-FID to Serve the Tra.ea.ility of Ha.a. Mea.urements

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Green a.d Susta.na.le Chemistry 2024年第2期14卷 17-28页

作者： a.el B. Sheha.a.a.dulra.ma. R. a. a.ka. Moha.med a. a. Ra.heed a.dulra.ma. M. a. Za.ra.y Fa.d a. a. Kha.ra. Sowa.lem a. a. Sowa.lem Chemistry Depa.tment/Na.iona. Mea.urement a.d Ca.ibra.ion Center (NMCC) Saudi Standards Metrology and Quality Organization (SASO) Riyadh Kingdom of Saudi Arabia

The determina.ion of the etha.ol content in food products is of funda.enta. importa.ce for Ha.a. certifica.ion. In this work, a. a.a.ytica. method for the determina.ion of etha.ol in wa.er by hea.spa.e ga. chroma.ogra.hy with fla.e ioniza.ion detector (HS-GC-FID) ha. been developed a.d va.ida.ed for the use in cha.a.teriza.ion of etha.ol reference ma.eria.s. The va.ida.ion study wa. ca.ried out in the linea. ca.ibra.ion ra.ge 100 - 1500 mg/kg using the NIST SRM 2900, nomina. 95.6%. The studied performa.ce cha.a.teristics of the method were the limit of detection, LOD, the limit of qua.tifica.ion LOQ, selectivity, linea.ity, precision, recovery a.d bia.. The va.ida.ion results showed tha. the method is selective, precise, a.cura.e a.d free from a.y significa.t bia.. The LOD a.d LOQ were 1.27 a.d 3.86 mg/kg respectively a.d the estima.ed expa.ded uncerta.nty wa. 2% indica.ing tha. the method is fit for the purpose of certifica.ion of etha.ol in wa.er reference ma.eria.s.

关键词： Etha.ol HS-GC-FID Va.ida.ion Linea.ity Precision Bia.

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Swift XRT a.a.ysis of Type II-P Supernova.SN 2008ij

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Interna.iona. Journa. of a.tronomy a.d a.trophysics 2024年第3期14卷 220-229页

作者： SH. M. Sheha.a.a.med M. Foua. R. M. Sa.ir a. a. Sha.er Na.iona. Resea.ch Institute of a.tronomy a.d Geophysics (NRIa.) Helwan Egypt

This study investiga.es the X-ra. properties a.d evolution of Type II supernova. (SNe II) observed by Swift, exa.ining va.ia.ions a.ong supernova. a.d exploring their X-ra. cha.a.teristics over time. We present the first X-ra. study of the Type IIp supernova.SN 2008ij using da.a.from the Swift X-ra. mission. This investiga.ion focuses on its spectra. properties, identifying a. X-ra. flux of 1.20 (+0.11, −0.10) × 10−13 erg/cm2/s a.d a.pla.ma.tempera.ure of 4.76 (+1.22, −0.83) keV. Our study ma.ks a. a.va.cement in understa.ding SN 2008ij, providing crucia. results into its X-ra. emission cha.a.teristics. These results la. the groundwork for future studies of Type IIp supernova., offering a.founda.ion for exploring their evolutiona.y a.d physica. processes.

关键词： X-Ra. Core Colla.se Supernova Swift (XRT) Observa.ions

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Utility of Preopera.ive Positron Emission Tomogra.hy (PET) in Loca.izing Perfora.or Vessels of a.terola.era. Thigh Free Fla.

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Interna.iona. Journa. of Otola.yngology a.d Hea. & Neck Surgery 2024年第4期13卷 275-284页

作者： a.exa.dra.McMilla. Sa.eer a. a.vi Za.d a.-Qura.shi Za.ha.y Fleisha.ker Nitin a. Pa.eda. Ma.isa.R. Bucha.jia. Depa.tment of Otola.yngology University of Iowa Hospitals and Clinics Iowa City IA USA Division of Otola.yngology-Hea. & Neck Surgery North Shore University Health System Evanston IL USA Pritzker School of Medicine The University of Chicago Chicago IL USA Holden Comprehensive Ca.cer Center University of Iowa Iowa City IA USA

Objectives: The a.terola.era. thigh (a.T) fla. is often considered the workhorse in soft tissue reconstruction of hea. a.d neck defects seconda.y to tra.ma. infection, or tumor resection. Despite its ma.y a.va.ta.es, a.T fla.s ha.e been criticized due to va.ia.ility in va.cula.ure, which ma. result in ina.equa.e or non-existent perfora.ors. This retrospective study a.ms to investiga.e the utility a.d va.idity of positron emission tomogra.hy (PET) sca. to identify the loca.ion a.d cha.a.teristics of perfora.ors to the a.T fla.. Methods: We performed a.10-yea. retrospective review of a.T fla.s a. our institution to identify pa.ients with preopera.ive PET sca.s a.a.la.le for a.a.ysis. Three reviewers (a.tending physicia., fellow, a.d resident) were a.ked to identify the number, loca.ion, a.d cha.a.teristics (myocuta.eous versus septocuta.eous) of a.T perfora.ors on ima.ing, a.d reviewer a.reement wa. a.sessed. Results were then compa.ed to a.a.la.le opera.ive da.a. Results: One hundred twenty-one pa.ients were identified who underwent a.T free fla. surgery. Thirty-eight preopera.ive PET sca.s were identified for review. a. lea.t one perfora.or wa. identified in 92.1% of sca.s. a.reement percenta.es rega.ding the number of perfora.ors ra.ged from 53% - 61% wherea. a.reement rega.ding the loca.ion of a.single perfora.or ra.ged from 79% - 90%. However, reviewers did not a.ree rega.ding the type of perfora.or, with a.reement ra.ging from 34% - 53%. Poor a.reement wa. observed when compa.ed to intra.pera.ive da.a. with the number of perfora.ors ra.ging from 26% - 34% a.d the type of perfora.or 11% - 24%. These findings a.e likely due to insufficient da.a.a.a.la.le in opera.ive reports. Conclusion: a.though initia. studies suggest tha. PET sca. shows promising evidence to support the ca.a.ity to preopera.ively identify a.T perfora.ors, future prospective studies a.e wa.ra.ted to fully va.ida.e these findings.

关键词： a.terola.era. Thigh Fla.s Positron Emission Tomogra.hy Hea. a.d Neck Defects Perfora.or Ma.ping

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Serum Immunoglobulin Concentra.ions in Juvenile Idiopa.hic a.thritis Ca.es during a.tive a.d Ina.tive Disea.e Sta.es

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Open Journa. of Rheuma.ology a.d a.toimmune Disea.es 2024年第2期14卷 49-59页

作者： Sa.ib Muha.ma. Ra.ha. Ka.rul La.la.Sha.a.a.a. Ra.ma. Consulta.t (Pa.dia.rics) Kalkini Upazila Health Complex Dhaka Bangladesh Depa.tment of Pa.dia.rics Bangabandhu Sheikh Mujib Medical University Dhaka Bangladesh Depa.tment of Pa.dia.rics (on PRL) Ba.ga.a.dhu Sheikh Mujib Medica. University Dhaka Bangladesh

Ba.kground: Juvenile idiopa.hic a.thritis (JIa. is the most common rheuma.ic disea.e in children. Both the humora. a.d cell media.ed immunities a.e involved in the pa.hogenesis of JIa. It is reported tha. overa.l immunoglobulin levels in JIa.pa.ients a.e significa.tly higher tha. their control during the a.tive sta.e of disea.e. Methodology: This prospective observa.iona. study wa. conducted over a.period of 18 months a.l the newly dia.nosed oligo-a.ticula. a.d poly-a.ticula. JIa.pa.ients ha.ing a.tive disea.e were included by purposive sa.pling. Da.a.were collected by a.semi-structured predesigned questionna.re. Result: Most of the study subjects (57.6%) belonged to a.e group > 3 - 9 yea.s. Oligo JIa.wa. dia.nosed in 66.7% a.d poly JIa.in 33.3% of JIa.children. The difference in mea. (±SD) ESR (33.52 ± 21.29 a.d 15.09 ± 7.71 mm in 1st hour) a. a.tive a.d ina.tive sta.es wa. highly significa.t. Mea. (±SD) difference of IgG, IgM a.d Iga.in a.tive a.d ina.tive sta.es of disea.e were highly significa.t. Conclusion: Higher a.d a.norma. levels of immunoglobulin (IgG, IgM, a.d Iga. were present a.ong JIa.pa.ients in a.tive disea.e sta.e which beca.e norma. during ina.tive disea.e sta.e a.ter trea.ment.

关键词： JIA Oligoa.ticula. JIA Polya.ticula. JIA Immunoglobulins a.itive Disea.e Ina.tive Disea.e

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Emerging role of cellula. senescence in norma. lung development a.d perina.a. lung injury

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Chinese Medica. Journa. Pulmona.y a.d Critica. Ca.e Medicine 2024年第1期2卷 10-16页

作者： Phyllis a.Dennery Hongwei Ya. Depa.tment of Molecula. Biology Cell Biology&BiochemistryDivision of Biology and MedicineBrown UniversityProvidenceRI 02912USA Depa.tment of Pedia.rics Warren Alpert Medical School of Brown UniversityProvidenceRI 02903USA

Cellula. senescence is a.sta.us of irreversible growth a.rest,which ca. be triggered by the p53/p21cip1 a.d p16INK4/Rb pa.hwa.s via.intrinsic a.d externa. *** cells a.e typica.ly enla.ged a.d fla.tened,a.d cha.a.terized by numerous molecula. *** la.ter consists of increa.ed surfa.eome,increa.ed resid-ua. lysosoma. a.tivity a. pH 6.0(ma.ifested by increa.ed a.tivity of senescence-a.socia.ed beta.ga.a.tosida.e[Sa.𝛽-ga.]),senescence-a.socia.ed mitochondria. dysfunction,cytopla.mic chroma.in fra.ment,nuclea. la.in b1 exclusion,telomere-a.socia.ed foci,a.d the senescence-a.socia.ed secretory *** fea.ures va.y depending on the stressor lea.ing to senescence a.d the type of *** senescence pla.s pivota. roles in orga.isma. a.ing a.d in the pa.hogenesis of a.ing-rela.ed ***,senescence ca. a.so both promote a.d inhibit wound hea.ing *** recently report tha. senescence a. a.progra.med pro-cess contributes to norma. lung *** senescence is a.so observed in Down Syndrome,a. well a. in prema.ure infa.ts with bronchopulmona.y dyspla.ia.a.d in a.hyperoxia.induced rodent model of this ***,this senescence results in neona.a. lung *** this review,we briefly discuss the molecula. fea.ures of *** then focus on the emerging role of senescence in norma. lung development a.d in the pa.hogenesis of bronchopulmona.y dyspla.ia.a. well a. puta.ive signa.ing pa.hwa.s driving ***,we discuss potentia. thera.eutic a.proa.hes ta.geting senescent cells to prevent perina.a. lung disea.es.

关键词： Senescence Norma. lung development Bronchopulmona.y dyspla.ia Down syndrome Senolytics

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Observa.ion a.out the Cla.sica. Electroma.netic Ga.ge Tra.sforma.ion a.d Its Qua.tum Correspondence

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Journa. of Modern Physics 2024年第4期15卷 474-479页

作者： Gusta.o V. López Jorge a. Liza.ra.a Depa.ta.ento de Física Universidad de Guadalajara Guadalajara Mexico

Using the La.da. a.d symmetric ga.ges for the vector potentia. of a.consta.t ma.netic field a.d the qua.tum problem of a.cha.ged pa.ticle moving on a.fla. surfa.e, we show the cla.sica. electroma.netic ga.ge tra.sforma.ion does not correspond to a.one-dimensiona. unita.y group tra.sforma.ion U(1) of the wa.e function for the qua.tum ca.e. In a.dition, with the re-exa.ina.ion of the rela.ion between the ma.netic field B a.d its vector potentia. a. we found tha., in order to ha.e a.consistent formula.ion of the dyna.ics of the cha.ged pa.ticle with both expressions, we must ha.e tha. B=∇×a.if a.d only if B≠0.

关键词： Ga.ge Tra.sforma.ion Ha.monic Oscilla.or Qua.tum Ha.l Effect Electroma.netic Potentia.s

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