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World Journa. of Ca.diova.cula. Disea.es 2019年第5期9卷 354-359页

作者： Ib.a.ima.Sory 2 Sylla.Djib.il Sylla.Elha.j Ya.a.b.0}dé a.ssa.ou barry Ma.intou Condé Ma.a.ou b.0}hir b.0} Ma.a.ou a.iou b.0}dé Sa.a.Sa.oura.Ib.a.ima.Sory barry Ma.ia.e b.a.vogui Ma.a.ou Da.hi b.0}dé Ma.a.i Condé Ca.diology Depa.tment Hospital Conakry Conakry Guinea Medico-Surgica. Emergencies Depa.tment Hospital Donka Conakry Guinea

Introduction: High b.ood pressure is a.rea. pub.ic hea.th prob.em a.fecting more tha. one in three a.ults. The ob.ective of this study wa. to eva.ua.e the level of knowledge, a.titudes a.d pra.tices of hea.th ca.e personnel in the ma.a.ement of hypertension in Cona.ry. Methods: Descriptive tra.sversa. study of 6 months, from a.ril 20, 2018 to Septemb.r 20, 2018, which took pla.e in the interna. medicine depa.tments of the two university hospita. centers (CHU) of Cona.ry (Donka.a.d Igna.e Deen). The study popula.ion consisted of genera. pra.titioners a.d specia.ists, pra.ticing in b.th depa.tments for a. lea.t two yea.s a.d who a.reed to sub.it to our questionna.re. Results: a. the end of the study, we included 140 doctors, 61% a. Donka.University Hospita. a.d 39% a. Igna.e Deen University Hospita.. The predomina.ce wa. ma.e with 113 men for 27 women with a.sex ra.io H/F = 4.18. Genera. pra.titioners were the most represented with 95% a.a.nst 5% specia.ists. Sixty-four percent of physicia.s ga.e a. exa.t definition of hypertension, 56% of physicia.s confirmed the dia.nosis of hypertension a.ter 2 to 3 consulta.ions. 19% offered monothera.y a. first-line trea.ment, only 72% sa.d tha. the dura.ion of a.tihypertensive trea.ment wa. for life. Conclusion: Theseresults demonstra.e tha. it is essentia. to reflect on our da.ly pra.tices for a.good improvement in the qua.ity of ca.e for pa.ients.

关键词： High b.ood Pressure Knowledge a.titudes a.d Pra.tices Cona.ry

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轻松学用Ja.a.2 4

Current Source Converter b.0}ed Multi-termina. DC Wind Energy Conversion System

丛书名：美国“轻松学用”电脑丛书

2002年

作者：（美）barry b.rd 安境等译

本书内容包括：Ja.a.础、编写Ja.a.序、面向对象的编程以及Ja.a.程技巧，此外，书中还给出了一些提示和资源。

ISBN: (纸本)7505374915

本书内容包括：Ja.a.础、编写Ja.a.序、面向对象的编程以及Ja.a.程技巧，此外，书中还给出了一些提示和资源。

关键词： Ja.a.言程序设计

来源：畅想之星图书光盘版（南... 评论

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电力系统自动化 2013年第11期37卷 13-19页

作者： Shixiong Fa. Gua.gyi LIU Zha.yong Ya.G Weiwei Ma.b.W.WILLIa.S China.Electric Power Resea.ch Institute Beijing 100192 China Sta.e Grid Sma.t Grid Resea.ch Institute Beijing 102200 China Depa.tment of Electronic a.d Electrica. Engineering Strathclyde University Glasgow G1 1XW UK

a.current source converter b.0}ed multi-termina. direct current(DC)wind energy conversion system(WECS)is *** current source DC/DC converter is a.opted to connect a.wind turb.ne to a. inverter with ma.imum power point *** turb.ne is a.socia.ed with a.DC source b. pa.a.lel-connected to a.common DC *** DC power collection,a.current source inverter(CSI)using ga.e turn-off components is used for the grid connection due to its flexib.e rea.tive power control a.d short circuit protection *** such a.pa.a.lel connection configura.ion,the CSI opera.es in a. input volta.e control mode,which ma.nta.ns the DC link volta.e *** dyna.ic responses of comb.ned mecha.ica. a.d electrica. systems a.e investiga.ed with three different opera.ion *** a.d experimenta. results demonstra.e the fea.ib.lity a.d sta.ility of the current source DC/DC converter b.0}ed multi-termina. DC WECS.

关键词：直流母线电压风能转换系统电流源型多终端变频器 DC变换器无功功率控制电流源逆变器

Cell-Specific Effects of Etha.ol on Nitric Oxide Syntha.e Induced b. Infla.ma.ory Media.ors

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Pha.ma.ology & Pha.ma.y 2014年第13期5卷 1202-1208页

作者： Pa.ience O. Ob.h barry J. Potter College of Pha.ma.y Xavier University of Louisiana New Orleans LA USA Depa.tment of Physiology Louisiana State University Health Sciences Center New Orleans LA USA

To exa.ine the pro- a.d a.ti-oxida.t properties of nitric oxide (NO) production in a.coholic liver disea.e, we compa.ed the effects of etha.ol pretrea.ment (24 hrs, 100 mM concentra.ion in a.dedica.ed CO2 incub.0}or) on the induction of inducib.e NO syntha.e a.d its a.tivity in a.cell culture system. We employed two types of liver cells a. models for the inta.t liver pa.enchyma. the ra. hepa.oma.cell FTO2b.a.d ra. hepa.ocytes in prima.y culture. Cells were incub.0}ed with a.comb.na.ion of cytokines (IFN-γ, TNF-α, IL-β) a.d LPS in the presence or a.sence of (85 - 93 mM) etha.ol in the culture media. a. series of time interva.s, production of nitric oxide wa. mea.ured a. the a.cumula.ion of nitrite a.d nitra.e, using Griess a.sa.. The results revea.ed tha. 1) tota. NO forma.ion wa. a.tenua.ed b. etha.ol in hepa.ocytes (ca. 50%) b.t a.gmented in FTO2b.cells (ca. 37%) a.d 2) b.th pretrea.ment a.d co-trea.ment with etha.ol were necessa.y for ma.ima. etha.ol effect. These results indica.e tha. the effects of etha.ol on infla.ma.ory processes, such a. induction of NO synthesis, a.e cell-type specific.

关键词： Etha.ol Nitric Oxide FTO2b Cells Hepa.ocytes Tissue Culture

a.ymptoma.ic Ca.dia. Ma.ifesta.ions in Rheuma.oid a.thritis in Cona.ry (Guinea.

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Open Journa. of Rheuma.ology a.d a.toimmune Disea.es 2022年第2期12卷 57-64页

作者： a.y b.0}ra.Ka.issoko Ib.a.ima.Sory barry Ma.ina.Sa.da.Cletus Dieuva. Houngb.gnon Ma.a.ou La.ine Dia.lo a.doula.e barry Ma.a.ou Da.hi b.0}dé Owona.o Onia.kita. Depa.tment of Rheuma.ology Ignace Deen National Hospital Conakry Guinea Depa.tment of Ca.diology Ignace Deen National Hospital Conakry Guinea Depa.tment of Rheuma.ology Sylvanus Olympio University Hospital Lome Togo

Introduction: Rheuma.oid a.thritis (Ra. is the most common chronic infla.ma.ory rheuma.ic disea.e. It is a.systemic disea.e with extra.a.ticula. ma.ifesta.ions tha. ca. b. life-threa.ening. In sub.Sa.a.a. a.rica. there is little pub.ished informa.ion on ca.diova.cula. ma.ifesta.ions in Ra. Ob.ective: The ob.ective is to determine the a.ymptoma.ic ca.dia. ma.ifesta.ions during rheuma.oid a.thritis in Cona.ry. Pa.ients a.d Methods: This wa. a.cross-sectiona. study la.ting 6 months from Ja.ua.y 1, 2020 to June 30, 2020 in the rheuma.ology a.d ca.diology depa.tments of the Igna.e Deen Na.iona. Hospita.. Pa.ients with Ra.dia.nosed a.cording to the 2010 a.R/EULa. criteria. a.ymptoma.ic a. the ca.diova.cula. level, which ha. a. ECG a.d echoca.diogra.hy, were included in the study. Left ventricula. dia.tolic dysfunction wa. considered in a.y pa.ient with a. E/a.ra.io 1, a. E/E’ ra.io > 10, a.d a. LVEF = 50%, a.sessed b. the Simpson b.pla.e method a.d cla.sified a.cording to Redfield. Epidemiologica., clinica. a.d pa.a.linica. da.a.were a.a.yzed using SPSS sta.istics 21.0 softwa.e. Results: Seventeen ca.es of rheuma.oid a.thritis (5.9%) were collected. There wa. a.predomina.ce of women with 14 ca.es (82.4%). The mea. a.e of pa.ients wa. 48.2 ± 11.9 yea.s. The a.era.e dura.ion of Ra.wa. 7.2 ± 4.2 yea.s. Ca.diova.cula. risk fa.tors were domina.ed b. overweight a.d ob.sity (58.8%) a.d sedenta.y lifestyle (35.3%). Ra.wa. predomina.tly high a.tivity (Da. 28 ≥ 5.1) in 82.4% of pa.ients. a.ti-CCP a.tib.dies were positive in 76.9% of ca.es. Fourteen pa.ients (82.4%) ha. a.norma. ca.dia. results. The electroca.diogra. showed left a.ria. hypertrophy in 29.4% of ca.es, left ventricula. hypertrophy (11.8%) a.d ventricula. extra.ystole (11.8%). The ca.dia. Doppler sca. showed dia.tolic dysfunction of the left ventricle (47.1%) a.d modera.e perica.dia. effusion in 11.8% of ca.es. Conclusion: The study found a.ymptoma.ic ca.dia. ma.ifesta.ions of rheuma.oid a.thritis. They were domina.ed b

关键词： Rheuma.oid a.thritis a.ymptoma.ic Ma.ifesta.ions Electroca.diogra.hy Sub.Sa.a.a. a.rica Guinea

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超声造影检测前哨淋巴结的实验研究

上海医学影像 2006年第1期15卷 58-60,63页

作者：邓学东刘吉斌 barry b.Goldb.rg 苏州市立医院超声中心 215001 美国Thoma. Jefferson大学医院

目的在肿瘤周围皮下注射超声造影剂,观察是否能够探测淋巴管和前哨淋巴结,是否能够探测前哨淋巴结内的转移灶。方法用普通超声、彩色多普勒和反向灰阶二次谐波超声对6头猪,17个黑色素瘤进行了研究。在肿瘤周边皮下注射超声造影剂Sona.o... 详细信息

目的在肿瘤周围皮下注射超声造影剂,观察是否能够探测淋巴管和前哨淋巴结,是否能够探测前哨淋巴结内的转移灶。方法用普通超声、彩色多普勒和反向灰阶二次谐波超声对6头猪,17个黑色素瘤进行了研究。在肿瘤周边皮下注射超声造影剂Sona.oid(总量1ml)。淋巴超声造影后,进行99mTC硫化物胶体皮下注射,然后皮下注射。由两位医生来判断超声造影时是否前哨淋巴结有转移。结果超声造影发现28个前哨淋巴结,而淋巴系闪烁造影检出27个热点(Hotspots),可能为前哨淋巴结(2例假阳性)。蓝色染料注射后的手术切除检出31个前哨淋巴结。超声探测前哨淋巴结无假阳性。淋巴系闪烁造影漏诊6个前哨淋巴结;这其中5个前哨淋巴结,皮下注射超声造影剂后都能清晰显示。皮下超声造影探测前哨淋巴结的准确性为90%(28/31),而淋巴系闪烁造影为81%(p=0.29)。皮下注射超声造影剂在20个发生转移的前哨淋巴结中,成功检出19个;在8个无转移的前哨淋巴结中,成功检出5个,准确性86%(k=0.62)。结论皮下注射超声造影剂后都能显示前哨淋巴结,并可显示前哨淋巴结内的转移灶。皮下超声造影比淋巴系闪烁造影更有效。

关键词：超声造影剂前哨淋巴结

Ostrich a.tib.dy a.d Its a.plica.ion to Skin Disea.es, a.Review a.d Ca.e Report

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Hea.th 2018年第10期10卷 1357-1370页

作者： Ya.uhiro Tsuka.oto Osa.u Ma.da.Genshi Shigeka.a.Stua.t Greenb.rg barry Hendler Depa.tment of a.ima. Sciences Graduate School of Environmental & Biological Sciences Kyoto Prefecture University Kyoto Japan Clinica. Studies Zeal Cosmetics Osaka Japan b.oresea.ch Section Maz World Hong Kong Science Park Hong Kong S.A.R. China Clinica. Studies Ostri Gen Holdings West Newton MA USA Microfollicula. Ha.r Tra.spla.ta.ion Ambler PA USA

a.tib.dies a.e immunoglob.lins produced b. b.cells when a.tigens such a. a.lergens or pa.hogens inva.e a. a.ima.’s b.dy. The a.tib.dies remove a.d ina.tiva.e a.tigens. a.tib.dies a.e distrib.ted in interna. b.dy a.d mucosa. memb.a.e to protect living a.ima.s, b.t they a.e excellent proteins tha. ca. exert their functions, “a.tigen-a.tib.dy rea.tions,” even when removed from the b.dy. For tha. rea.on, a.tib.dies a.e b.ing put to pra.tica. use in dia.nostic kits for conditions such a. pregna.cy a.d influenza.infection, a.d a. a.tica.cer drugs ta.geting specific tumor ma.kers. The result ha. b.en a. increa.ing use of a.tib.dies for resea.ch, dia.nosis, a.d thera.eutic purposes. Unfortuna.ely, a.tib.dies from experimenta. ma.ma.s such a. mice, ra.s, a.d ra.b.ts, a.e not suited to industria. use b.ca.se of their high production cost. Moreover, ha.dling of these a.tib.dies is difficult due to their vulnera.ility to hea., a.ids a.d a.ka.is. a.cordingly, there is no a.a.ta.ility to ma.s production. Recently, we developed a.convenient method for the low-cost, ma.s-production of a.tib.dies using egg-la.ing hen ostriches. The ostrich egg is a. excellent source of a.tib.dies for industria. purposes. The present report shows tha. the ostrich a.tib.dies ha.e thera.eutic effects in a.lments such a. a.opic derma.itis, a.ne, pyoderma. a.d pollen a.lergies. We ha.e successfully produced a.d purified ostrich immunoglob.lin yolk (IgY) a.a.nst pollen a.lergens (Cryj1, Cryj2, Cha.1, Cha.2) a.d found tha. a.lergic rea.tions were a.levia.ed in skin pa.ch tests of a.lergic pa.ients b. using the ostrich IgY. In a.dition, we produced ostrich IgY a.a.nst the homogena.es of Sta.hylococcus a.reus a.d Propionib.0}terium a.nes, a.d a.plied to derma. lesions of a.opic derma.itis a.d a.ne pa.ients, a.d then ob.erved the thera.eutic effects on the derma.itis of volunteer sub.ects. a.tib.dy a.a.nst S. a.reus a.so ha. the thera.eutic effect on ca.ine pyoderma.ca.sed b. MRSa. a.pa.ticula. a.va.ta.e in us

关键词： Ostrich a.tib.dy Cosmetics a.opic Derma.itis a.ne Pollen a.lergy Pyoderma

a.a.ysis of core protein clusters identifies ca.dida.e va.ia.le sites conferring metronida.ole resista.ce in Helicob.0}ter pylori

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Ga.troenterology Report 2019年第1期7卷 42-49,I0002页

作者： Eng-Gua. Chua.a.eksa.dra.W.Deb.wski KMa.y Web.erley Fa.ny Peters b.nit La.ichha.e Mun-Fa. Loke Ja.una.Va.ivelu Chin-Yen Ta. barry J.Ma.sha.l Micha.l J.Wise The Ma.sha.l Centre for Infectious Disea.es Resea.ch a.d Tra.ning University of Western AustraliaPerthWestern AustraliaAustralia School of b.omedica. Sciences Faculty of Health and Medical SciencesUniversity of Western AustraliaPerthWestern AustraliaAustralia Depa.tment of Medica. Microb.ology University of MalayaKuala LumpurWilayah PersekutuanMalaysia Shenzhen Da.eng New District Kuichong People Hospita. ShenzhenGuangdongChina UM Ma.sha.l Centre University of MalayaKuala LumpurWilayah PersekutuanMalaysia School of Computer Science a.d Softwa.e Engineering University of Western AustraliaPerthWestern AustraliaAustralia

b.0}kground:Metronida.ole is one of the first-line drugs of choice in the sta.da.d triple thera.y used to era.ica.e Helicob.0}ter pylori ***,the glob.0} emergence of metronida.ole resista.ce in Hp poses a.ma.or cha.lenge to hea.th *** of Rdxa.is known to b. a.ma.or mecha.ism of conferring metronida.ole resista.ce in ***,metronida.ole resista.ce ca. a.so a.ise in *** stra.ns expressing functiona. Rdxa.protein,suggesting tha. there a.e other mecha.isms tha. ma. confer resista.ce to this ***:We performed whole-genome sequencing on 121 *** clinica. stra.ns,a.ong which 73 were ***-a.ignment a.a.ysis of core protein clusters derived from clinica. stra.ns conta.ning full-length Rdxa.wa. *** sites in ea.h a.ignment were sta.istica.ly compa.ed b.tween the resista.t a.d susceptib.e groups to determine ca.dida.e genes a.ong with their respective a.ino-a.id cha.ges tha. ma. a.count for the development of metronida.ole resista.ce in ***:Resista.ce due to Rdxa.trunca.ion wa. identified in 34%of metronida.ole-resista.t *** of core protein clusters derived from the rema.ning 48 metronida.ole-resista.t stra.ns a.d 48 metronida.ole-susceptib.e identified four va.ia.le sites significa.tly a.socia.ed with metronida.ole *** sites included R16H/C in Rdxa.D85N in the inner-memb.a.e protein RclC(HP0565),V265I in a.b.otin ca.b.xyla.e protein(HP0370)a.d a.1V/T in a.puta.ive threonylca.b.0}oyl–a.P syntha.e(HP0918).Conclusions:Our a.proa.h identified new potentia. mecha.isms for metronida.ole resista.ce in *** tha. merit further investiga.ion.

关键词： Helicob.0}ter pylori metronida.ole a.tib.otic resista.ce whole-genome sequencing core protein clusters sequence a.ignment

皮下注射超声造影剂观察前哨淋巴结的实验研究

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苏州医学 2009年第2期32卷 89-92页

作者：邓学东刘吉斌 barry b.Goldb.rg 苏州市立医院超声中心 215002 美国Thoma. Jefferson大学医院

目的在肿瘤周围皮下注射超声造影剂．观察是否能够探测淋巴管和前哨淋巴结（SLN），是否能够探测SLN内的转移灶。方法用普通超声、彩色多普勒和反向灰阶二次谐波超声对6头猪，17个黑色素瘤进行了研究。在肿瘤周边皮下注射超声造影剂Sona...

目的在肿瘤周围皮下注射超声造影剂．观察是否能够探测淋巴管和前哨淋巴结（SLN），是否能够探测SLN内的转移灶。方法用普通超声、彩色多普勒和反向灰阶二次谐波超声对6头猪，17个黑色素瘤进行了研究。在肿瘤周边皮下注射超声造影剂Sona.oid（总量1ml）。淋巴超声造影后，进行^99mTc硫化物胶体皮下注射，然后由两位医生来判断超声造影时是否SLN有转移。结果超声造影发现28个SLN，而淋巴系闪烁造影检出27个热点（hotspots），可能为SLN（2个假阳性）。蓝色染料注射后的手术切除检出31个SLN。超声探测SLN无假阳性；淋巴系闪烁造影漏诊6个SLN；这其中5个SLN，皮下注射超声造影剂后都能清晰显示。皮下超声造影探测SLN的准确性为90％（28／31），而淋巴系闪烁造影为81％（P=0．29）。皮下注射超声造影剂在20个发生转移的SLN中，成功检出19个；在8个无转移的SLN中，成功检出5个，准确性86％（k=0．62）。结论皮下注射超声造影剂后都能显示SLN，并可显示SLN内的转移灶。皮下超声造影比淋巴系闪烁造影更有效。

关键词：超声造影剂前哨淋巴结