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Hea.t Fa.lure in Children: Epidemiologica., Etiologica. a.d Dia.nostic a.pects in Dia.nia.io Children’s Hospita. (Senega.)

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World Journa. of Ca.diova.cula. Disea.es 2020年第1期10卷 12-18页

作者： M. Leye I. b.0}se R. Godonou D. a. a.fa.gla.D. M. b.0}N. N. Dia.a.a.a. b. sibabi sibabi a. Phiri M. Dioum F. Dia.y S. a.a.i K. Gueye N. R. Dia.ne b. M. Diop Unité de Forma.ion et de Recherche en sciences de la.sa.té Université de Thiès Thiès Sénégal Fa.ulté de Médecine de Pha.ma.ie et d’odontologie Université Cheikh Anta Diop de Dakar Dakar Sénégal

Introduction: Hea.t fa.lure is a.ma.or ca.se of morb.dity a.d morta.ity in children. The a.thors a.med to report the epidemiologica. a.d etiologica. cha.a.teristics of hea.t fa.lure (HF) in children in Senega.. Pa.ients a.d Methods: This wa. a.retrospective study conducted a. the Children’s Hospita. of Dia.nia.io (CHD) from 01-01-2016 to 31-12-2017. Children a.ed 0 to 15 yea.s with hea.t fa.lure confirmed b. echoca.diogra.hy were included. Results: Sixty-six children were a.mitted for hea.t fa.lure. The preva.ence of HF wa. 5.3‰. The mea. a.e of the children wa. 41.59 months ± 53.35 months (ra.ge: 0 to 168 months). The 0 - 5 a.e group wa. the most represented (n = 48;72.72%). The HF concerned 38 b.ys a.d 28 girls, a.sex ra.io (M/F) of 1.36. The ma.ority of our pa.ients ca.e from the semi-urb.0} a.ea.(42.4%). The etiology of HF wa. represented in order of frequency b. congenita. hea.t disea.e, rheuma.ic hea.t disea.e a.d ca.diomyopa.hy with 59.09% of ca.es, 22.73% of ca.es a.d 7.58% of ca.es respectively. It wa. unknown in 4.54% of the ca.es. a. echoca.diogra.hy, the left ventricula. ejection fra.tion (LVEF) wa. impa.red (less tha. 50%) in 19 pa.ients, in 29.2% of ca.es with a. a.era.e of 64% +/- 15.16% (extremes: 24% a.d 86%). a.emia.wa. the comorb.dity most commonly a.socia.ed with their condition (n = 33%;50%). Conclusion: Hea.t fa.lure in children is uncommon. The ma.n etiology is represented b. congenita. hea.t disea.e.

关键词： Hea.t Fa.lure Children Congenita. Hea.t Disea.e Senega.

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Ma.a.ement a.d Evolution of Multiple Myeloma.with Rena. Fa.lure in Developing Countries: The Ca.e of the Sylva.us Olympio University Hospita. in Lome, Togo

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Open Journa. of Nephrology 2022年第4期12卷 441-450页

作者： Kossi a.omola.Sa.i Eyra. Fia.yo Yoa. Ma.a.ui a.ekoudi Viwa.e Koffi Tessio La.ne Odilon b.a.ome b.0}omta.Dola.ma.a.odélé Jona.ha. Sa.i a.dou-Ra.uf sibabi Za.a.ou Tcha.lina. Na.eta.Owona.o Onia.ita. Nephrology Hemodialysis Department of CHU Sylvanus Olympio University of Lomé Lomé Togo Rheuma.ology Depa.tment of The Seconda.y Hospita. of b. University of Lomé Lomé Togo Nephrology Depa.tment of CHU Ka.a University of Kara Kara Togo Rheuma.ology Depa.tment of CHU Sylva.us Olympio University of Lomé Lomé Togo

b.0}kground: Rena. fa.lure (RF) is a.frequent complica.ion during multiple myeloma.(MM) a.d sometimes revea.s the disea.e. The media. surviva. of MM pa.ients with RF is shorter tha. tha. of pa.ients with myeloma.without rena. involvement. a.though pa.ient surviva. ha. b.en prolonged with the new thera.ies, the media. surviva. does not exceed five to seven yea.s. Few da.a.on this sub.ect a.e a.a.la.le in sub.Sa.a.a. a.rica. Ob.ectives: To describ. the thera.eutic ma.a.ement a.d evolution of MM with RF in a.developing country like Togo. Method: This wa. a.retrospective descriptive a.d a.a.ytica. study which took pla.e over a.period of ten yea.s (2010-2019) a.d included the records of pa.ients with MM a.cording to the 2009 a.d/or 2014 IMWG criteria. hospita.ized or followed up in the nephrology a.d rheuma.ology depa.tments of the CHU-SO with a.GFR Results: During the study period, 78 pa.ients with MM ha. rena. fa.lure (55.7%). Thera.eutica.ly, hygienic a.d dieta.y mea.ures were dicta.ed in 84.6% of ca.es (68 pa.ients). Rehydra.ion wa. performed in 38 ca.es (48.7%);a.ka.iniza.ion of urine in 10 ca.es (12.8%);use of a.tib.otics in 36 ca.es (46.2%), NSa.Ds in 51 ca.es (65.4%);use of b.phosphona.es in 36 ca.es (46.6%). Surgica. immob.liza.ion b. screw-pla.e osteosynthesis wa. performed in 02 pa.ients. Nephrologica.ly, 8 pa.ients underwent ESRD. The different chemothera.y protocols used were Melpha.a.-Prednisone in 70% of ca.es, Melpha.a.-Cyclophospha.ide-Prednisone in 26.7% of ca.es a.d Cyclophospha.ide-Prednisone in 3.3%. The media. overa.l surviva. wa. 8 months. The media. surviva. wa. 13 months in pa.ients who recovered from rena. fa.lure versus 2 months in those who did not recover from rena. fa.lure (p = 0.0030). Of the 78 pa.ients in our series, 22 pa.ients ha. died (28.2%). Conclusion: Despite rena. fa.lure, the a.exa.ia. protocol a.d b.phosphona.es a.e still widely used in comb.na.ion with symptoma.ic trea.ment with significa.t results.

关键词： Rena. Fa.lure Multiple Myeloma Ma.a.ement Evolution Togo

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