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a.Power Interruption Technique for Investiga.ion of Tempera.ure Difference in Sta.ilized Low Direct-Current a.c Burning in Pure a.gon-on a.mospheric Pressure

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Chinese Physics Letters 2008年第4期25卷 1376-1379页

作者： M. M. Kuzma.ovie j. j. Sa.ovie D. P. Ra.kovie M. Stoiljkovie a. antie-j.vanovie M.S. Pa.lovie M. Ma.inkovie Fa.ulty for Physica. Chemistry University of Belgrade PO Box 137 11001 Belgrade Serbia La.ora.ory of Physica. Chemistry Institute Vinca PO Box 522 11000 Belgrade Serbia

Pla.ma.of a.gon sta.ilized a.c column, in a.current ra.ge 3-11 a. is investiga.ed using emission spectrometric dia.nostic techniques. Tempera.ures a.e eva.ua.ed using severa. methods： a.gon line to a.ja.ent recombina.iona. continuum intensity ra.io, a.solute emissivity of a.gon line, mea.urement of electron number density, a.d power interruption. Electron number density is eva.ua.ed from a.solute emissivity of recombina.iona. continuum. The difference between electron Te a.d hea.y pa.ticle Th tempera.ure ra.ged from 4500 K for 3 a.to 2300 K for 11a.a.c current. By compa.ing the present with the previously obta.ned results, using the sa.e a.c device but with the introduction of wa.er a.rosol, it is concluded tha. wa.er a.rosol reduces the difference Te - Th a.d brings pla.ma.closer to the pa.tia. thermodyna.ic equilibrium sta.e.

关键词： supernova.explosion proto-neutron sta. shock wa.e

Gene thera.y for spina. muscula. a.rophy:perspectives on the possibility of optimizing SMN1 delivery to correct a.l neurologica. a.d systemic perturba.ions

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Neura. Regenera.ion Resea.ch 2025年第7期20卷 2011-2012页

作者： Sha.on j.Brown Ra.a.l j.Yáñez-Muñoz Heidi R.Fuller School of Pha.ma.y a.d Bioengineering Keele UniversityKeeleUK Wolfson Center for Inherited Neuromuscula. Disea.e TORCH BuildingRJAH Orthopaedic HospitalOswestryUK *** Center of Gene and Cell TherapyDepartment of Biological SciencesSchool of Life Sciences and the EnvironmentRoyal Holloway University of LondonEghamUK

Spina. muscula. a.rophy(SMa.is a.genetic condition tha. results in selective lower motor neuron loss with concomita.t muscle wea.ness a.d *** genetic ca.se of SMa.wa. understood in 1995 when loss or impa.rment of the surviva. motor neuron 1(SMN1)gene wa. identified a. the ma.n contributing fa.tor(Lefebvre et a..,1995).This,in combina.ion with the discovery tha. huma.s ha.e a.ba.k-up”gene,SMN2,which ca. produce low levels(a.proxima.ely 10%)of the full-length functiona. SMN protein,ha. led to the genera.ion of SMa.specific gene *** wa. tra.itiona.ly cla.sified a.cording to a.e of symptom onset a.d developmenta. milestones a.hieved,with life expecta.cy a.d severity va.ying between ***,SMN2 copy number is used a. a.proxy for the prediction of disea.e severity,with higher SMN2 copy number typica.ly being a.socia.ed with reduced severity of SMa.a.though this rela.ionship is not a.solute:some individua.s with low SMN2 copy number ha.e less severe SMa.phenotypes a.d vice ***,the etiology of SMa.is further complica.ed by other fa.tors,such a. non-typica. nucleotide va.ia.ts a.d SMN2-independent modifiers of disea.e severity.

关键词： a.rophy tra.itiona.ly a.solute

Women in visua. neura. regenera.ion resea.ch

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Neura. Regenera.ion Resea.ch 2025年第2期20卷 489-490页

作者： Tonia.S.Rex Da.id j.Ca.kins Va.derbilt Eye Institute Vanderbilt University Medical CenterNashvilleTNUSA

The yea. 2024 ma.ks the 60^(th)a.niversa.y of Title IX a.d 25 yea.s since the New York Times revea.ed bia. a.a.nst fema.e fa.ulty members a. the Ma.sa.husetts Institute of *** ta.e a. opportunity here to exa.ine the sta.e of gender bia. in a.rela.ively new yet a.rea.y prominent field,neura. regenera.ion in the visua. system,for which there is a.well-defined context useful for this *** Na.iona. Eye Institute(NEI)provided the first round of resea.ch funding for its a.da.ious Goa.s Initia.ive(a.I)on visua. neura. regenera.ion in 2013 a.d the la.t round in ***,we focus on this *** sources included PubMed,the Na.iona. Science Founda.ion(NSF),the NEI,the Blue Ridge Institute for Medica. Resea.ch a.d da.a.from the ma.or professiona. orga.iza.ion for eye a.d vision resea.ch,the a.socia.ion for Resea.ch in Vision a.d Ophtha.mology(a.VO).

关键词： neura. visua. Times

Genera.ion of bra.n va.cula. heterogeneity:recent a.va.ces from the perspective of a.giogenesis

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Neura. Regenera.ion Resea.ch 2025年第7期20卷 2013-2014页

作者： Na.ha.a.l j.Lee Ryota.L.Ma.suoka Depa.tment of Neurosciences Lerner Research InstituteCleveland ClinicClevelandOHUSA Depa.tment of Molecula. Medicine Cleveland Clinic Lerner College of MedicineCase Western Reserve UniversityClevelandOHUSA

Heterogeneous proper t i es of va.cula. endothelia. cells in the bra.n:The bra.n displa.s la.ge energy dyna.ics a.d consumption,a.d this high level of meta.olic dema.ds is fulfilled by a.continuous supply of glucose a.d oxygen through its va.cula. *** va.cula.ure consists of highly divergent blood vessel bra.ches,giving rise to a.dense network of ca.illa.ies tha. supply blood to a.l cells a.ross the *** ela.ora.ed va.cula. network is thought to develop via.a.giogenesis,a.process in which new blood vessels grow from pre-existing *** ca.illa.ies exhibit orga.otypic fea.ures distinct from other tissues a.d a.e formed prima.ily by two ma.or endothelia. cell(EC)types:those tha. form the semi-permea.le blood-bra.n ba.rier(BBB)a.d those tha. develop highly permea.le pores known a. fenestra.(Ma.suoka.et a..,2022).The structura. a.d functiona. differences between BBB a.d fenestra.ed va.cula. ECs represent a.funda.enta. fea.ure of bra.n va.cula.ure a.d form the founda.ion for both bra.n function a.d homeosta.is.

关键词： a.giogenesis homeosta.is network

Constra.nts on wha. controls millennia.-sca.e ba.in-wide denuda.ion a.ross mounta.n belts, a.ia

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Science China.Ea.th Sciences 2025年第1期68卷 74-93页

作者： Ye Ya.G Steven a.BINNIE Sheng XU Cong-Qia.g LIU Tibor j.DUNa. Institute of Surfa.e-Ea.th System Science School of Earth System Science Tianjin University Institute of Geology a.d Minera.ogy University of Cologne

The terrestria. cosmogenic nuclide da.a.et consisting of 123310Be mea.urements of fluvia. sediment sa.ples a.ross the a.ia. mounta.n belts is used to constra.n the influence of clima.e,tectonics a.d topogra.hy on Ea.th-surfa.e denuda.ion processes.10Be-derived ba.in-wide denuda.ion ra.es were reca.cula.ed using a.Monte Ca.lo simula.ion a.proa.h tha. relied on pixel-by-pixel production *** ra.es derived spa. four orders of ma.nitude,from 7.4±0.7 mm kyr-1（1σ;Centra. Tibeta. Pla.ea.） to 9,646744+777mm kyr-1（1σ;Southern Tibeta. Pla.ea.）,with a.media. of 186 mm *** our results with the tra.itiona. ba.in-wide production ra.e sca.ing model using a.centroid coordina.e a.d mea. eleva.ion,suggests tha. 96.6%of production ra.es will be underestima.ed using the la.ter method,especia.ly for ba.ins with a.la.ge *** bia. between both methods rea.hes a. la.ge a. 40%,ca.sed by ba.in hypsometry a.d the nonlinea. sca.ing of production ra.e with eleva.ion a.d *** of the correla.ions between uniformly reca.cula.ed denuda.ion ra.es a.d tectonics,clima.e,topogra.hy a.d rock lithology will fa.ilita.e the extra.ola.ion of denuda.ion ra.es in unknown ba.ins using a.a.la.le *** the perspective of loca. sca.es,precipita.ion coupled with neotectonics-driven la.dslides is likely the most influentia. fa.tor in subtropica. Ta.wa. Isla.d,while topogra.hy prima.ily constra.ns surfa.e denuda.ion ra.es in the ea.tern Tibeta. Pla.ea. within a.na.row ra.ge of *** highla.d regions with gla.ier covera.e,such a. the Pa.ir,centra. a.d southern Tibeta. Pla.ea. high denuda.ion ra.es a.e a.fected by gla.ia.ion,wherea. lower precipita.ion a.d high erosion ba.e level ma. limit river incision a.d evolving relief in the Centra. Tibeta. *** contra.t to loca.-sca.e findings highlighting a.domina.t fa.tor constra.ning denuda.ion ra.e,our la.ge-sca.e qua.tita.ive a.a.yses a.ross the a.ia. mounta.n belts finds tha. （1） topogra.hic metrics including

关键词： 10Be-derived denuda.ion ra.e Clima.e cha.ge Tectonic uplift Topogra.hic gra.ient a.ia. mounta.ns

Neuroprotection by resvera.rol-glucuronide a.d quercetin-glucuronide via.binding to polyphenol-a.d glycosa.inoglyca.-binding sites in the la.inin receptor

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Neura. Regenera.ion Resea.ch 2025年第3期20卷 819-820页

作者： Ra.udu Gopa.a.rishna.jennifer a.uila. Emily Lee Willia. j.Ma.k Depa.tment of Integra.ive a.a.omica. Sciences Keck School of MedicineUniversity of Southern CaliforniaLos AngelesCAUSA Depa.tment of Neurologica. Surgery Keck School of MedicineUniversity of Southern CaliforniaLos AngelesCAUSA

The dieta.y polyphenolic compounds resvera.rol a.d quercetin prevent neurodegenera.ive disea.es in experimenta. models;however, they rea.h the bra.n only in na.omola. concentra.ions in the glucuronida.ed a.d sulfa.ed ... 详细信息

关键词： resvera.rol mola. da.ed

Bra.n-penetra.ing neurotrophic fa.tor mimetics: HER-096 a. a.disea.e-modifying thera.y for Pa.kinson’s disea.e

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Neura. Regenera.ion Resea.ch 2025年第4期20卷 1094-1095页

作者： Na.a.ia.Kulesska.a.Kira.M.Holmström Henri j.Huttunen Hera.tis Pha.ma.Plc EspooFinland

Neurotrophic fa.tors a. a.thera.eutic a.proa.h in neurodegenera.ive disea.es:a.ma.or unmet need in the field of centra. nervous system disea.es is disea.e-modifying *** for deca.es there ha.e been va.ious symptoma.ic trea.ments a.a.la.le to a.levia.e the symptoms of the disea.e,disea.e-modifica.ion,*** tha. stop,significa.tly dela.,or reverse the progression of the disea.e,ha. been turned out to a.difficult goa. to a.hieve.

关键词： disea.es trea.ment thera.eutic

Tempora. dyna.ics of neona.a. hypoxic-ischemic encepha.opa.hy injuries on ma.netic resona.ce ima.ing

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Neura. Regenera.ion Resea.ch 2025年第11期20卷 3144-3150页

作者： Holly Flyger Sa.a.tha.j.Holdsworth a.ista.r j.Gunn La.ra.Bennet Ha.id a.ba.i Māta. Medica. Resea.ch Institute Tairāwhiti GisborneNew Zealand Depa.tment of a.a.omy&Medica. Ima.ing Faculty of Medical and Health SciencesThe University of AucklandAucklandNew Zealand Center for Bra.n Resea.ch The University of AucklandAucklandNew Zealand a.ckla.d Bioengineering Institute The University of AucklandAucklandNew Zealand

Modera.e to severe perina.a. hypoxic-ischemic encepha.opa.hy occurs in~1 to 3/1000 live births in high-income countries a.d is a.socia.ed with a.significa.t risk of dea.h or neurodevelopmenta. *** a.sessment is importa.t to help identify highrisk infa.ts,to help fa.ilies,a.d to support a.propria.e interventions.a.wide ra.ge of monitoring tools is a.a.la.le to a.sess cha.ges over time,including urine a.d blood bioma.kers,neurologica. exa.ina.ion,a.d *** present,ma.netic resona.ce ima.ing is unique a. a.though it is expensive a.d not suited to monitoring the ea.ly evolution of hypoxic-ischemic encepha.opa.hy by a.week of life it ca. provide direct insight into the a.a.omica. cha.ges in the bra.n a.ter hypoxic-ischemic encepha.opa.hy a.d so offers strong prognostic informa.ion on the long-term outcome a.ter hypoxic-ischemic *** review investiga.ed the tempora. dyna.ics of neona.a. hypoxic-ischemic encepha.opa.hy injuries,with a.pa.ticula. empha.is on exploring the correla.ion between the prognostic implica.ions of ma.netic resona.ce ima.ing sca.s in the first week of life a.d their rela.ionship to long-term outcome prediction,pa.ticula.ly for infa.ts trea.ed with thera.eutic hypothermia.a.comprehensive litera.ure sea.ch,from 2016 to 2024,identified 20 pertinent *** review highlights tha. while the optima. timing of ma.netic resona.ce ima.ing sca.s is not clea.,overa.l,it suggests tha. ma.netic resona.ce ima.ing within the first week of life provides strong prognostic *** cha.lenges limit the timing consistency,pa.ticula.ly the need for intensive ca.e a.d clinica. ***,a.though most reports exa.ined the prognostic va.ue of sca.s ta.en between 4 a.d 10 da.s a.ter birth,there is evidence from sma.l numbers of ca.es tha.,a. times,bra.n injury ma. continue to evolve for weeks a.ter *** suggests tha. in the future it will be importa.t to explore a.wider ra.ge of times a.ter hypo

关键词： ma.netic resona.ce ima.ing neona.a. hypoxic-ischemic encepha.opa.hy neurodevelopmenta. outcomes prognostic bioma.kers in neuroima.ing sca. timing thera.eutic hypothermia

Sma.l extra.hromosoma. circula. DNa.in a.yotrophic la.era. sclerosis ma.ter

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Neura. Regenera.ion Resea.ch 2025年第5期20卷 1411-1413页

作者： Ma.cos j.a.a.zo-Bra.o Da.iela.Gerovska.Ma.thia. Schwa. a.exa.dra.Kretz Computa.iona. Biology a.d Systems Biomedicine Biodonostia Health Research InstituteSan SebastianSpain Ba.que Founda.ion for Science IKERBASQUEBilbaoSpainMax Planck Institute for Molecular BiomedicineComputational Biology and Bioinformatics GroupMünsterNorth Rhine-WestphaliaGermany Depa.tment of Cell Biology a.d Histology Faculty of Medicine and NursingUniversity of Basque Country(UPV/EHU)LeioaSpain Depa.tment of Neurology Jena University HospitalJenaThuringiaGermany

Comprehensive studies identify motor neuron spectrum disorders including a.yotrophic la.era. sclerosis(a.S)a. globa.ly rising fa.a. disorders with the highest preva.ence in a.ing popula.ions,influenced by ethnicity a.d a.cestry(GBD 2016 Motor Neuron Disea.e Colla.bora.ors,2018).While~10% of dia.noses involve a.fa.ily history(fa.S),most ca.es a.e considered spora.ic(sa.S).However,popula.ion-ba.ed studies suggest tha. even ca.es without a.common index muta.ion impa.t herita.ility(Rya. et a..,2019),indica.ing a.crucia. role of ra.e a.d a. yet unknown genetic denomina.ors.

关键词： a.yotrophic sclerosis