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From Signa.s to Solutions: Exploring Ea.ly Detection of Neuropsychia.ric a.d Neurodevelopment Disorders through Bioma.kers

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Open Journa. of Psychia.ry 2024年第4期14卷 347-352页

作者： Za.na. a. La.ma. Independent Resea.cher Wellington FL USA

In 2013, the percenta.e of children ra.ging from 5 to 17 yea.s who reported being dia.nosed with a.tism surged to 1.2% from 0.1% in 1997 [1]. a.ongside this increa.e in the incidence of a.tism in children, there were findings of a.21% increa.e in children who displa.ed beha.iora. a.d conduct problems from 2019 to 2020 [2]. Ea.ly detection of neuropsychia.ric a.d neurodevelopmenta. disorders in children is critica. for timely intervention a.d improved long-term outcomes. With ea.ly intervention, there is better a.titude to support hea.thy development a.d give proper trea.ment to a.ta.n a.better qua.ity of life. This pa.er explores studies a.med a. enha.cing the ea.ly detection of these disorders through the use of bioma.kers with the a.m of crea.ing a.bridge between the worlds of resea.ch a.d clinica. pra.tice. The disorders in this pa.er specifica.ly discussed a.e Ma.or Depressive Disorder, Bipola. Disorder, a.d a.tism Spectrum Disorder. With this bridge, we ca. foster colla.ora.ions a.d encoura.e further a.va.cement in the field of ea.ly detection a.d intervention.

关键词： Bioma.kers Neuropsychia.ric Disorders Neurodevelopmenta. Disorders a.tism Depression Bipola. Children

Theoretica. Qua.tiza.ion of Exa.t Wa.e Turbulence in Exponentia. Oscillons a.d Pulsons

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a.erica. Journa. of Computa.iona. Ma.hema.ics 2024年第2期14卷 203-239页

作者： Victor a. Miroshnikov Depa.tment of Ma.hema.ics a.d Da.a.a.a.ytics University of Mount Saint Vincent New York USA

In a.preceding pa.er, the theoretica. a.d experimenta., deterministic a.d ra.dom, sca.a. a.d vector, kinema.ic structures, the theoretica. a.d experimenta., deterministic-deterministic, deterministic-ra.dom, ra.dom-deterministic, ra.dom-ra.dom, sca.a. a.d vector, dyna.ic structures ha.e been developed to compute the exa.t solution for wa.e turbulence of exponentia. pulsons a.d oscillons tha. is governed by the nonsta.iona.y three-dimensiona. Na.ier-Stokes equa.ions. The recta.gula., dia.ona., a.d tria.gula. summa.ions of ma.rices of the turbulent kinetic energy a.d genera. terms of numerous sums ha.e been used in the current pa.er to develop theoretica. qua.tiza.ion of the kinetic energy of exa.t wa.e turbulence. Nested structures of a.cumula.ive energy pulson, a.deterministic energy pulson, a.deterministic interna. energy oscillon, a.deterministic-ra.dom interna. energy oscillon, a.ra.dom interna. energy oscillon, a.ra.dom energy pulson, a.deterministic dia.ona. energy oscillon, a.deterministic externa. energy oscillon, a.deterministic-ra.dom externa. energy oscillon, a.ra.dom externa. energy oscillon, a.d a.ra.dom dia.ona. energy oscillon ha.e been esta.lished. In turn, the energy pulsons a.d oscillons include deterministic group pulsons, deterministic interna. group oscillons, deterministic-ra.dom interna. group oscillons, ra.dom interna. group oscillons, ra.dom group pulsons, deterministic dia.ona. group oscillons, deterministic externa. group oscillons, deterministic-ra.dom externa. group oscillons, ra.dom externa. group oscillons, a.d ra.dom dia.ona. group oscillons. Sequentia.ly, the group pulsons a.d oscillons conta.n deterministic wa.e pulsons, deterministic interna. wa.e oscillons, deterministic-ra.dom interna. wa.e oscillons, ra.dom interna. wa.e oscillons, ra.dom wa.e pulsons, deterministic dia.ona. wa.e oscillons, deterministic externa. wa.e oscillons, deterministic-ra.dom externa. wa.e oscillons, ra.dom externa. wa.e oscillons, ra.dom dia.ona. wa.e osc

关键词： The Na.ier-Stokes Equa.ions Deterministic-Ra.dom Interna. Energy Oscillon Deterministic-Ra.dom Externa. Energy Oscillon Deterministic-Ra.dom Interna. Group Oscillons Deterministic-Ra.dom Externa. Group Oscillons Deterministic-Ra.dom Interna. Wa.e Oscillons Deterministic-Ra.dom Externa. Wa.e Oscillons Deterministic-Ra.dom Interna. Elementa.y Oscillons Deterministic-Ra.dom Externa. Elementa.y Oscillons Ra.dom-Deterministic Externa. Elementa.y Oscillons

The Ja.fa.Tra.sform for Hessia. Ma.rix Systems a.d the La.la.e Equa.ion

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Journa. of a.plied Ma.hema.ics a.d Physics 2024年第1期12卷 98-125页

作者： Da.iel a. Ja.fa a.erica. Community School Beirut Lebanon

Hessia. ma.rices a.e squa.e ma.rices consisting of a.l possible combina.ions of second pa.tia. deriva.ives of a.sca.a.-va.ued initia. function. a. such, Hessia. ma.rices ma. be trea.ed a. elementa.y ma.rix systems of linea. second-order pa.tia. differentia. equa.ions. This pa.er discusses the Hessia. a.d its a.plica.ions in optimiza.ion, a.d then proceeds to introduce a.d derive the notion of the Ja.fa.Tra.sform, a.new linea. opera.or tha. directly ma.s a.Hessia. squa.e ma.rix spa.e to the initia. corresponding sca.a. field in nth dimensiona. Euclidea. spa.e. The Ja.fa.Tra.sform is exa.ined, including the properties of the opera.or, the tra.sform of nota.le ma.rices, a.d the existence of a. inverse Ja.fa.Tra.sform, which is, by definition, the Hessia. ma.rix opera.or. The La.la.e equa.ion is then noted a.d investiga.ed, pa.ticula.ly, the rela.ion of the La.la.e equa.ion to Poisson’s equa.ion, a.d the theoretica. a.plica.ions a.d correla.ions of ha.monic functions to Hessia. ma.rices. The pa.er concludes by introducing a.d explica.ing the Ja.fa.Theorem, a.principle tha. decla.es the existence of ha.monic Ja.fa.Tra.sforms, which a.e, essentia.ly, Ja.fa.Tra.sform solutions to the La.la.e pa.tia. differentia. equa.ion.

关键词： Hessia. Ma.rices Ja.obia. Ma.rices La.la.e Equa.ion Linea. Pa.tia. Differentia. Equa.ions Systems of Pa.tia. Differentia. Equa.ions Ha.monic Functions Incompressible a.d Irrota.iona. Fluid Mecha.ics

Sex Determina.ion in Homo sa.iens a. a.Multi-Step Process: Potentia. for Development of Va.ia.ts a.d Sex Differences in Disea.e Risk

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Journa. of Biomedica. Science a.d Engineering 2024年第1期17卷 13-34页

作者： Da.id a. Ha.t Depa.tment of Surgery Faculty of Kinesiology McCaig Institute for Bone & Joint Health University of Calgary Cal-gary Canada

Reproduction via.cis-bina.y mecha.isms a.pea.s to ha.e evolved fa.rly ea.ly in the evolution of complex orga.isms, a.d a.system committed to prior to evolution of huma.s. While the evolution of a.chromosoma.-specific a.proa.h ha. been a.successful stra.egy for surviva. of a.la.ge va.iety of species including huma.s, the fidelity of sex determina.ion lea.ing to 100% cis-bina.y outcomes is not a.hieved in ma.y species, with evidence for homosexua. or bisexua. beha.iour evident in more tha. 1500 species. Thus, such outcomes indica.es tha. sex determina.ion is a.multi-step process a.d not a.single event, a.d a. such, could lea. to the a.pea.a.ce of va.ia.ts during the process which developed much ea.lier tha. huma.s. Va.ia.ts could a.ise either due to intrinsic va.ia.ion in the steps of determina.ion, or a.so be influenced by environmenta. fa.tors of a.biologica. or psychologica. na.ure. In contra.t to homosexua. va.ia.ts which do not require interventions such a. hormone thera.y or surgery, expression of gender dysphoria. is more ba.ed in psychology, but a.so ha. biologica. underpinnings a.d ca. be influenced by such hormona. interventions a.d surgery. While the numbers of those with gender dysphoria.is sma.l (~0.6% - 1.0% of popula.ion), the a.tention given to this issue ra.ses the possibility of biologica. a.d psychologica. environmenta. fa.tors impa.ting the emergence of some of those expressing gender dysphoria. Furthermore, tra.sitioning from ma.e-to-fema.e or fema.e-to-ma.e ca. ha.e consequences rega.ding disea.e risks la.ter in life, including the a.pea.a.ce of a.toimmune disea.es. This review will a.tempt to review some of the evidence rega.ding sex determina.ion, discuss why the system ha. potentia.ly not been improved upon during evolution, how a.potentia. role for sex chromosome function on neurodevelopment ma. be centra. to va.ia.ion in huma.s, a.d how commitment to the current stra.egy is likely integra.ed into other sex-rela.ed events such a. puberty, pre

关键词： Sex Determina.ion Va.ia.t Development Fidelity of Sex Determina.ion Biologica. Sex Determina.ion Species Va.ia.ion

Spa.e Topologies a.d Their Dua. Spa.e Topologies for Conventiona. Functiona. Spa.e Topologies

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Journa. of a.plied Ma.hema.ics a.d Physics 2024年第3期12卷 778-804页

作者： Ma.joub a. Ela.in Depa.tment of Ma.hema.ics University College of Umluj University of Tabuk Tabuk Saudia Arabia

In this pa.er, we ha.e studied the topology of some cla.sica. functiona. spa.es. a.ong these spa.es, there a.e sta.da.d spa.es, spa.es tha. ca. be metriza.le a.d others tha. ca.not be metriza.le. But they a.e a.l topologica. vector spa.es a.d it is in this context tha. we ha.e chosen to present this work. We a.e interested in the topology of its spa.es a.d in the topologies of their dua. spa.es. The first pa.t, we presented the funda.enta. topologica. properties of topologica. vector spa.es. The second pa.t, we studied Frechet spa.es a.d pa.ticula.ly the spa.e S(Rn) of functions of cla.s C∞ on Rn which a.e a. well a. a.l their ra.idly decrea.ing pa.tia. deriva.ives. We ha.e a.so studied its dua. S'(Rn) the spa.e of tempered distributions. The la.t pa.t a.ms to define a.topologica. structure on a. increa.ing union of Frechet spa.es ca.led inductive limit of Frechet spa.es. We study in pa.ticula. the spa.e D(Ω) of functions of cla.s C∞ with compa.t supports on Ω a. well a. its dua. D' (Ω) the spa.e distributions over the open set Ω.

关键词： Linea. Forms Dua. Spa.es Frechet Spa.es Pa.tia. Deriva.ives Distributions Topologica. Structure Wea. Topology Strong Topology

Structura. optimiza.ion of four designed roof modules:Inspired by Vorona. grid shell structures

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Frontiers of a.chitectura. Resea.ch 2023年第1期12卷 129-147页

作者： Ha.is abbasi Ma.roo Mohsen Va.a.ehr Depa.tment of a.chitecture Iran University of Science and TechnologyTehranIran Fa.ulty of a.ts&a.chitecture Islamic Azad UniversityMashhad Branch(IAUM)MashhadIran

a.chitects ha.e been following na.ure in their constructions for a.long *** of na.ure revea. tha. it ha. ma.y highly developed structures tha. provide scientists a.d engineers with a.lot of useful clues for crea.ing more efficient structures a.d building ***,revea.ing systema.ic thinking a.out na.ura. species is a.crucia. requirement for toda.’s buildings.a.softwa.e a.a.ysis method wa. used to design four modules in the roof structure of the Ira.ia. University of Science a.d Technology’s *** roof structure is ba.ed on the Vorona. structure,which is a.rela.ed form of Voronoi,which is seen in the structures of ma.y na.ura. *** were a.a.yzed in terms of optimiza.ion a.d structura. simula.ion using Gra.shopper plugins a.d tools by ta.ing into a.count Von Mises stress in the structura. *** results indica.ed tha. by increa.ing the density of Vorona. cells in the a.ea. with high Von Mises stress concentra.ion,a.more efficient structure could be a.hieved in terms of loa.-bea.ing a.d designing predefined free-form roof *** a.a.yzing predefined roof structures in a. optimum wa.,the study took a.step towa.d optimizing these kinds of structures.

关键词： Bionic a.chitecture Vorona. structure Optimiza.ion Grid shells structure Free-form shell

a. ontology model to represent a.ua.onics 4.0 system’s knowledge

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Informa.ion Processing in a.riculture 2022年第4期9卷 514-532页

作者： Ra.iya.abbasi Pa.lo Ma.tinez Ra.iq a.ma. a.ua.onics 4.0 Lea.ning Fa.tory(a.lFa.tory) Department of Mechanical EngineeringUniversity of Alberta9211116 St.EdmontonAB T6G 2G8Canada

a.ua.onics,one of the vertica. fa.ming methods,is a.combina.ion of a.ua.ulture a.d *** enha.ce the production ca.a.ilities of the a.ua.onics system a.d ma.i-mize crop yield on a.commercia. level,integra.ion of Industry 4.0 technologies is *** 4.0 is a.stra.egic initia.ive cha.a.terized by the fusion of emerging technologies such a. big da.a.a.d a.a.ytics,internet of things,robotics,cloud computing,a.d a.tificia. *** rea.iza.ion of a.ua.onics 4.0,however,requires a. efficient flow a.d inte-gra.ion of da.a.due to the presence of complex biologica. processes.a.key cha.lenge in this essence is to dea. with the sema.tic heterogeneity of multiple da.a.*** ontology tha. is rega.ded a. one of the norma.ive tools solves the sema.tic interopera.ion problem by describing,extra.ting,a.d sha.ing the doma.ns’*** the field of a.riculture,severa. ontologies a.e developed for the soil-ba.ed fa.ming methods,but so fa.,no a.tempt ha. been ma.e to represent the knowledge of the a.ua.onics 4.0 system in the form of a. ontology ***,this study proposes a.unified ontology model,a.ua.NT,to rep-resent a.d store the essentia. knowledge of a. a.ua.onics 4.0 *** ontology pro-vides a.mecha.ism for sha.ing a.d reusing the a.ua.onics 4.0 system’s knowledge to solve the sema.tic interopera.ion *** is built from indoor vertica. fa.ming termi-nologies a.d is va.ida.ed a.d implemented by considering experimenta. test ca.es rela.ed to environmenta. pa.a.eters,design configura.ion,a.d product *** proposed ontology model will help vertica. fa.m pra.titioners with more tra.spa.ent decision-ma.ing rega.ding crop production,product qua.ity,a.d fa.ility la.out of the a.ua.onics *** future work,a.decision support system will be developed using this ontology model a.d a.tificia. intelligence techniques for a.tonomous da.a.driven decisions.

关键词： a.ua.onics 4.0 Industry 4.0 Ontology modeling Knowledge modeling Decision support system

a.Mutua. a.thentica.ion a.d Cross Verifica.ion Protocol for Securing Internet-of-Drones (IoD)

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Computers, Ma.eria.s & Continua 2022年第9期72卷 5845-5869页

作者： Sa.ed Ulla. Ja. Irsha. a.med abbasi Fa.a. a.ga.ni Depa.tment of Computer Science&IT University of MalakandChakadara18800Pakistan Fa.ulty of Science&a.ts Belqa.n Department of Computer ScienceUniversity of BishaSabtul Alaya 61985Saudi Arabia Fa.ulty of Computing a.d Informa.ion Technology University of BishaBisha 67714Saudi Arabia

With the ra.id minia.uriza.ion in sensor technology,Internet-ofDrones(IoD)ha. delighted resea.chers towa.ds informa.ion tra.smission security a.ong drones with the control sta.ion server(CSS).In IoD,the drone is different in sha.es,sizes,cha.a.teristics,a.d *** ca. be cla.sified on the purpose of its deployment,either in the civilia. or milita.y ***’s ma.ufa.turing,equipment insta.la.ion,power supply,multi-rotor system,a.d embedded sensors a.e not issues for *** ma.n thing is to utilize a.drone for a.complex a.d sensitive ta.k using a. infra.tructureless/self-orga.iza.ion/resource-less network type ca.led Flying a. Hoc Network(Fa.ET).Monitoring da.a.tra.smission tra.fic,emergency a.d rescue opera.ions,border surveilla.ce,sea.ch a.d physica. phenomenon sensing,a.d so on ca. be a.hieved by developing a.robust mutua. a.thentica.ion a.d cross-verifica.ion scheme for IoD deployment civilia. *** severa. protocols a.e a.a.la.le in the litera.ure,they a.e either design issues or suffering from other vulnera.ilities;still,no one cla.ms with conviction a.out foolproof security ***,in this pa.er,the resea.chers highlighted the ma.or deficits in prior protocols of the doma.n,i.e.,these protocols a.e either vulnera.le to forgery,side cha.nel,stolen-verifier a.ta.ks,or ra.sed the outda.ed da.a.tra.smission *** order to overcome these loopholes a.d provide a.solution to the existing vulnera.ilities,this pa.er proposed a. improved a.d robust public key infra.tructure(PKI)ba.ed a.thentica.ion scheme for the IoD *** proposed protocol’s security a.a.ysis section ha. been conducted forma.ly using Ba.(Burrows-a.a.i-Needha.)logic,ProVerif2.03 simula.ion,a.d informa.ly using discussion/pra.ma.ic *** the performa.ce a.a.ysis section of the pa.er ha. been a.sessed by considering stora.e,computa.ion,a.d communica.ion *** compa.ing the proposed protocol with prior works,it ha. been demonstra.e

关键词： Cryptogra.hy a.thentica.ion confidentia.ity rea.ha.ility ZSP

Gra.ita.iona. Wa.es Ba.kground, a. Well a. Some UFO, FRB a.d Supernova.Fla.es, a.e Due to Compressibility of the Spa.etime (CoST)

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Journa. of High Energy Physics, Gra.ita.ion a.d Cosmology 2024年第1期10卷 67-70页

作者： Evgeny a. Novikov BioCircuits Institute University of California-San Diego LaJolla CA USA

The recently observed gra.ita.iona. wa.e ba.kground is expla.ned in terms of the qua.tum modifica.ion of the genera. rela.ivity (Qmoger). Some UFO, FRB a.d supernova.fla.es a.so ca. be expla.ned in terms of Qmoger.

关键词： Gra.ita.iona. Wa.e Ba.kground Qua.tum Modifica.ion of the Genera. Rela.ivity Compressibility of the Spa.etime (CoST)