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Influence of cryogenic thermal cycling treatment on the thermophysical properties of carbon/carbon composites between room temperature and 1900℃

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Journal of Materials Science & Technology 2018年第2期34卷 409-415页

作者： mao-yan Zhang Ke-zhi Li Xiao-hong Shi Ling-jun Guo Lei Feng Tao Duan State Key Laboratory of Solidification Processing Northwestern Polytechnical University

Influence of cryogenic thermal cycling treatment （from -120 ℃ to 120 ℃ at 1.3 × 10^-3 Pa） on the thermo- physical properties including thermal conductivity （TC）, thermal diffusivity （TD）, specific heat （SH） and coefficient of thermal expansion （CTE） ranging from room temperature to 1900 ℃ of carbon/carbon （C/C） composites in x-y and z directions were studied. Test results showed that fiber/matrix interracial debonding, fiber pull-out and microcracks occurred after the cryogenic thermal treatment and they increased significantly with the cycle number increasing, while cycled more than 30 times, the space ofmicrodefects reduced obviously due to the accumulation of cyclic thermal stress. TC, TD, SH and CTE of the cryogenic thermal cycling treated C/C composites were first decreased and then increased in both directions （x-y and z directions） with the increase of thermal cycles. A model regarding the heat conduction in cryogenic thermal cycling treated C/C composites was proposed.

关键词： Carbon/carbon composites Cryogenic thermal cycling Thermal conductivity Thermal expansion

Numerical Analysis of Artificial Electron Heating Effects on Polar Mesospheric Winter Echoes

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Journal of Electronic Science and Technology 2020年第3期18卷 287-295页

作者： Safi Ullah Hai-Long Li Abdur Rauf Lu-Yao Fu mao-yan Wang Lin Meng School of Electronic Science and Engineering University of Electronic Science and Technology of ChinaChengdu 610054

In this paper,an analytical model is used to analyze the modulated polar mesospheric winter echoes(PMWE).The winter parameters were introduced to simulate the effects of different parameters during the artificial electron heating of *** important role of the charged dust particle in the creation of PMWE is confirmed *** is found that during the heating of PMWE,the increases of the dust size,dust charge,electron temperature,initial electron density,and ion-neutral collision frequency cause the increase of the electron density irregularity,and hence the PMWE ***,with increasing the dust density,the electron density irregularity and the PMWE strength decrease.

关键词： Artificial ionospheric heating electron density irregularities polar mesospheric winter echoes(PMWE) space plasma physics(numerical simulation)

Association between depression and malnutrition in pulmonary tuberculosis patients:A cross-sectional study

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World Journal of Clinical Cases 2022年第14期10卷 4395-4403页

作者： Xue-E Fang Dan-Ping Chen Ling-Ling Tang yan-Jun mao Department of Tuberculosis Shanghai Pulmonary Hospital Affiliated to Tongji UniversityShanghai 200000Shanghai ProvinceChina Department of Nursing Shanghai Pulmonary Hospital Affiliated to Tongji UniversityShanghai 200000Shanghai ProvinceChina

BACKGROUND Depression has been reported to be prevalent in patients with pulmonary tuberculosis(PTB).Moreover,several clinical symptoms of PTB and depression overlap,such as loss of appetite and ***,the association between depression and malnutrition in TB patients has not been fully *** To explore the association between depression and malnutrition in patients with *** This hospital-based cross-sectional study included patients with PTB in Shanghai Pulmonary Hospital Affiliated to Tongji University from April 2019 to July *** Patient Health Questionnaire-9(PHQ-9)scale was used to evaluate *** cut-off value was set at 10,and the nutritional state was determined by the body mass index(BMI).In addition,the Quality of Life Instruments for Chronic Diseases was employed to establish the quality of life(QOL).Univariable analysis and multivariable analysis(forward mode)were implemented to identify the independent factors associated with *** A total of 328 PTB patients were screened for *** were excluded for missing demographic data,four excluded for missing nutrition status,and sixteen for missing QOL ***,300 PTB patients were subjected to *** found that depressive state was present in 225 PTB patients(75%).The ratio of malnutrition in the depressive PTB patients was 45.33%.Our results revealed significantly lower BMI,hemoglobin,and prealbumin in the depression group than in the control group(P<0.05).Moreover,the social status differed significantly(P<0.05)between the *** addition,glutamic pyruvic transaminase and glutamic oxaloacetic transaminase in the depression group were significantly higher than those in the control group(P<0.05).Multivariable logistic regression analysis showed that BMI[odds ratio(OR)=1.21,95%confidence interval(CI):1.163-1.257,P<0.001]and poor social function(OR=0.95,95%CI:0.926-0.974,P=0.038)were independently associated with ***

关键词： Depression Pulmonary tuberculosis Malnutrition Quality of life Comorbidity China

Carcinosarcoma of common bile duct:A case report

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World Journal of Gastrointestinal Oncology 2023年第3期15卷 562-570页

作者： Yao Yao Hong-Gang Xiang Lei Jin Ming Xu Shu-yan mao Division of Gastroenterology and Hepatology Shanghai Pudong New Area People’s HospitalShanghai University of Medicine and Health SciencesShanghai 200120China Division of General Surgery Shanghai Pudong New Area People’s HospitalShanghai University of Medicine and Health SciencesShanghai 200120China Division of Pathology Shanghai Pudong New Area People’s HospitalShanghai University of Medicine and Health SciencesShanghai 200120China

BACKGROUND Carcinosarcomas of the common bile duct(CBD)are an extremely rare finding in the clinical *** on a review of 12 literatures,3 cases had the imaging features of *** are prone to distant metastasis,as they possess clinical features of both carcinoma and sarcoma,and generally have with a poor *** to the small number of cases reported,clinical experience in the diagnosis and treatment of the disease is *** SUMMARY The patient was a 75-year-old woman who had experienced recurrent chills with nausea and vomiting for 3 *** tomography,magnetic resonance imaging,endoscopic ultrasonography and endoscopic retrograde cholangiopancreatography led to the diagnosis of malignant tumor of the *** patient ultimately underwent cholecystectomy,CBD resection,and *** pathological examination revealed carcinosarcoma of the CBD,and the latest follow-up showed that the patient is recovering *** on previous case reports,some carcinosarcoma has ossification characteristics in *** it is misdiagnosed as biliary calculi,the use of laser lithotripsy in surgery may lead to tumor *** and narrow band staining of mucosa are very important for *** We herein present a rare case of carcinosarcomas of the CBD,we found the tumours may have imaging features of polypoid growth and ossification only when the sarcomal components are bone differentiation,while show soft tissue shadow when non bone *** of diagnosis depends greatly upon postoperative pathological examination and the adjuvant treatment has not been established,which leads to the poor prognosis.

关键词： Carcinosarcoma Sarcocarcinoma Sarcomatoid carcinoma Extrahepatic bile duct tumor Common bile duct tumor Case report

Optimization Design of the Multi-Layer Cross-Sectional Layout of An Umbilical Based on the GA-GLM

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China Ocean Engineering 2024年第2期38卷 247-254页

作者： yanG Zhi-xun YIN Xu FAN Zhi-rui yan Jun LU Yu-cheng SU Qi mao yandong WANG Hua-lin Institute of marine machinery College of Mechanical and Electrical EngineeringHarbin Engineering UniversityHarbin 150001China State Key Laboratory of Structural Analysis Optimization and CAE Software for Industrial EquipmentDepartment of Engineering MechanicsDalian University of TechnologyDalian 116024China Ningbo Institube of Dalian University of Technology Ningbo 315040China

Marine umbilical is one of the key equipment for subsea oil and gas exploitation,which is usually integrated by a great number of different functional components with *** layout of these components directly affects manufacturing,operation and storage performances of the *** the multi-layer cross-sectional layout design of the umbilical,a quantifiable multi-objective optimization model is established according to the operation and storage *** the manufacturing factors,the multi-layering strategy based on contact point identification is introduced for a great number of functional ***,the GA-GLM global optimization algorithm is proposed combining the genetic algorithm and the generalized multiplier method,and the selection operator of the genetic algorithm is improved based on the steepest descent *** algorithm is used to find the optimal solution in the global space,which can converge from any initial layout to the feasible layout *** feasible layout solution is taken as the initial value of the generalized multiplier method for fast and accurate ***,taking umbilicals with a great number of components as examples,the results show that the cross-sectional performance of the umbilical obtained by optimization algorithm is better and the solution efficiency is ***,the multi-layering strategy is effective and *** design method proposed in this paper can quickly obtain the optimal multi-layer cross-sectional layout,which replaces the manual design,and provides useful reference and guidance for the umbilical industry.

关键词： umbilical cross-sectional layout multi-layers GA-GLM optimization

Conjugation of Chitooligosaccharide-5-fluorouracil with Bovine Serum Albumin

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Chinese Chemical Letters 2006年第11期17卷 1495-1498页

作者： Rong Min WANG Jing Feng SONG Yu Feng HE Juan Juan mao yan LI Key Laboratory of Polymer Materials of Gansu Province Institute of Polymer Northwest Normal University Lanzhou 730070

The interaction between chitooligosaccharide-5-fluorouracil （COS-5FU） and bovine serum albumin （BSA） was studied by fluorescence spectroscopy. It was found that an energy transfer between COS-5FU and BSA had been occurred. The binding constants were calculated, k298K=1.175×10^4 L·mol^-1. Based on the mechanism of energy transfer of dipole-dipole interaction between the donor and acceptor, the distance between BSA and COS-SFU was determined.

关键词： Chitooligosaccharide-5-fluorouracil BSA fluorescence spectroscopy.

Amide as an efficient ligand in the palladium-catalyzed Suzuki coupling reaction in water/ethanol under aerobic conditions

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Chinese Chemical Letters 2011年第6期22卷 738-740页

作者： Hai yang Liu Kun Wang Hai yan Fu mao Lin Yuan Hua Chen Rui Xiang Li Key Lab of Green Chemistry and Technology Ministry of Education the Institute of Homogeneous Catalysis College of Chemistry Sichuan University Chengdu 610064 China

Amide,which is derived from proline and is inexpensive and air-stable,has been synthesized and characterized by ~1H NMR,^（13）C NMR,and *** was found to be an efficient ligand in the palladium-catalyzed Suzuki cross-coupling *** the Pd/amide catalytic system,aryl bromides can be coupled with phenylboronic acid in ethanol/water（1：2;v/v） in excellent yields even with a low Pd loading of 0.01 mol%.Moreover,the scope of the reaction is broad,and a wide variety of functional groups are tolerant.

关键词： Suzuki cross-coupling Palladium catalyst Aryl bromides Amide Water

Novel Coil Winding Method to Realize Pot Heated Evenly

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Journal of Electronic Science and Technology 2015年第2期13卷 107-111页

作者： mao-yan Wang Hai-Long Li Meng Zhang Zhi-Tao Xu Cui-Lin Zhong Jun Xu School of Physical Electronics University of Electronic Science and Technology of China 41st Institute of China Electronics Technology Group Corporation Centre of Integrated Electronics Shenzhen Institutes of Advanced TechnologyChinese Academy of Sciences

To solve the problem about the inhomogeneous thermal effect of pot heated by coils along the circumference, a novel coil winding method is proposed and compared with the general winding method in the paper. First, based on the Biot-Savart law and Ampere＇s rule, the magnetic induction generated by a straight current carrying conductor and a current loop is discussed, respectively. Then the novel coil winding method is developed by adjusting the location of inhomogeneous joints. The joints are periodically scattered along the circumferential direction and symmetrically designed around the central *** results show that the quite non-uniform temperature in the base of pot at the circular direction is effectively improved by using the proposed winding method. The potential danger produced by high temperature at some region of coils plate is *** is energy-efficient and safe for residential appliances.

关键词： winding inhomogeneous straight joints periodically scattered carrying circular adjusting heating

PRODUCTION IN PICHIAPASTORISAND CHARACTERIZATION OF GENETIC ENGINEERED CHIMERIC HBV/HEV VIRUS-LIKE PARTICLES

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Chinese Medical Sciences Journal 2004年第2期19卷 78-83页

作者： Hong-zhaoLi Hong-yingGang Qiang-mingSun XiaoLiu yan-bingMa mao-shengSun Chang-baiDai InstituteofMedicalBiology ChineseAcademyofMedicalSciences＆PekingUnionMedicalCollegeKunming650118

Objective To investigate the presentation of a neutralization epitope-containing peptide antigen of hepatitis E virus (HEV) on chimeric virus-like particles (VLPs) of hepatitis B surface antigen (HBsAg). MethodsThe gene fragment corresponding to amino acids (aa) 551-607 (HEnAg) of HEV capsid protein, which contains the only neutralization epitope identified to date, was fused via a synthetic glycine linker in frame with the gene of HBsAg. The resulted fusion gene was then integrated through transformation into the genome of Pichiapastorisunder the control of a methanol-induced alcohol oxidase 1 (AOX1) promoter and expressed intracellularly. The expression products in the soluble cell extracts were characterized by Western blot, ELISA, CsCl density gradient analysis, and electron microscopic visualiza-tion. Results The novel fusion protein incorporating HBsAg and the neutralization epitope-containing HEnAg was expressed successfully in Pichiapastoriswith an expected molecular weight of approximately 32 kD. It was found to possess the ability to assemble into chimeric HBV/HEV VLPs with immunological, physical and morphological characteristics akin to HBsAg particles. Not only did the chimeric VLPs show high activity levels in a HBsAg particle-specific ELISA but they were also strongly immunoreactive with hepatitis E (HE) positive human serum in a HEV specific ELISA, indicating that HEnAg peptide fragments were exposed on VLP surfaces and would be expected to be readily accessible by cells and molecules of the immune system. Similarity between chimeric VLPs to highly immunogenic HBsAg particles may confer good immuno-genicity on surface-displayed HEnAg. Conclusion The chimeric HBV/HEV VLPs produced in this study may have potential to be a recombinant HBV/HEV bivalent vaccine candidate.

关键词： hepatitis E virus neutralization epitope virus-like particles