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Cytokine landscapes of pregnancy:mapping gestational immune phases

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Gynecology and Obstetrics Clinical Medicine 2024年第1期4卷 56-64页

作者： sulagna Dutta Pallav sengupta fong fong Liew Basic Medical sciences Department College of MedicineAjman UniversityAjmanUAE Department of Biomedical sciences Gulf Medical UniversityAjmanUAE Department of Preclinical sciences Faculty of DentistryMAHSA UniversityKuala LumpurMalaysia

Background synchronised physiological adaptations occur during pregnancy to achieve systemic,immune and neuroendocrine equilibrium in the mother's body,allowing semiallogenic fetal *** text Depending on the cytokine profile alterations occurring through pregnancy,the latter can be divided into three distinct *** the first immunological phase of pregnancy,proinflammatory cytokines promote inflammatory reactions needed for *** the second phase,a possible change from proinflammatory to anti-inflammatory cytokines creates a symbiosis between maternal and fetal components,ensuring fetal *** the third phase,inflammatory and cytolytic cytokines operate again to reinforce an inflammatory environment for *** article offers a detailed account of immune adaptations during pregnancy and highlights the distinctive cytokine profiles that mark each *** By providing a simplified depiction of pregnancy phases based on cytokine profiles,the article aims to inspire more research in reproductive immunology and improve the management of pregnancy-related inflammation and infection.

关键词： pregnancy mother alterations

高校专利审查对发明披露和许可策略的影响研究

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预测 2014年第6期33卷 43-48,53页

作者：陈强常旭华 Patrick s.W.fong 同济大学经济与管理学院上海200092 香港理工大学建筑及房地产学系

专利审查机制是提升高校专利质量的重要途径,本文通过构建博弈模型探讨了专利审查对教职工发明披露和高校专利许可策略的影响。结果表明:专利审查对教职工发明披露有负面作用,但对高价值发明披露影响较弱;高校专利质量较差时须进行审查... 详细信息

专利审查机制是提升高校专利质量的重要途径,本文通过构建博弈模型探讨了专利审查对教职工发明披露和高校专利许可策略的影响。结果表明:专利审查对教职工发明披露有负面作用,但对高价值发明披露影响较弱;高校专利质量较差时须进行审查,但不可与提高教职工许可收益同时实施,专利审查比例与许可收益分配比例及转化成本负相关;最后,专利审查应与高校的许可策略配套实施,仅当预期未来收益较低时才可对外许可未经审查的教职工发明。

关键词：高校技术转移专利审查发明披露专利许可策略

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自由日记：1936

Effects of Ving Tsun sticking-hand training on upper-limb sensorimotor performance in community-dwelling middle-aged and older adults: A randomized controlled trial

作者： K. s. fong

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International Journal of Nursing sciences 2020年第1期7卷 29-34页

作者： Joanne W.Y.Chung shirley s.M.fong Yang Gao Timothy T.T.Yam Yvonne T.C.Chak Joyce C.Y.Leung Thomas K.s.Wong Department of Health and Physical Education Education University of Hong KongHong KongChina school of Nursing and Healthcare Hong Kong Nang Yan College of Higher EducationHong KongChina Hong Kong Martial Arts Institute Hong KongChina school of Public Health University of Hong KongHong KongChina Department of sport and Physical Education Hong Kong Baptist UniversityHong KongChina Hong Kong Christian service Hong KongChina school of Nursing and Health studies Open University of Hong KongHong KongChina Department of social Work and social Administration University of Hong KongHong KongChina

Objective:To evaluate the effects of Ving Tsun(VT)sticking-hand training on upper-limb joint position sense and muscular performance in community-dwelling middle-aged and older ***:Thirty-three adults were randomly allocated to either a VT group or a control *** VT group received VT sticking-hand training twice per week for 3 *** were taken before and after the intervention *** primary outcome was elbow-joint repositioning error,which was measured by an elbow-joint passive positioning and active repositioning test using a universal *** outcomes were upper-limb muscles'peak force and time taken to reach peak force as measured by a hand-held ***:No significant time,group or time-by-group interaction effects were found for elbow-joint repositioning error or upper-limb muscle peak force *** flexor time to peak force decreased by 33.8%from pre-test to post-test in the VT group(P=0.007).shoulder abductor,internal and external rotator,and elbow extensor times to peak force decreased by 30.0%-35.9%in the VT%roup(Psions:VT sticking-hand training does not improve elbow-joint position sense or the maximum strength of upper-limb muscles in middle-aged and older ***,VT can improve shoulder flexor muscles'time to reach peak force in these *** had no obvious effect on the time required to reach peak force in other shoulder muscles and elbow extensors.

关键词： Aged Exercise movement techniques Joint position sense Middle aged Muscle strength Upper extremities

Development of an Enteric Bacterial Enrichment Broth and Its Performance for Isolation of Clinically significant Bacterial Pathogens from stool

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Open Journal of Medical Microbiology 2021年第1期11卷 1-17页

作者： Timothy s. Horseman Michael B. Lustik Keith s. K. fong Department of Clinical Investigation Tripler Army Medical Center Honolulu USA

Background: Early detection and accurate identification of foodborne pathogen outbreaks is an important public health function. Increased clinical adoption of multiplex PCR assays or culture independent diagnostic tests (CIDT) correlates to more stool specimens sent to public health laboratories (PHL) for characterization. Isolation and confirmation of enteric bacterial pathogens can prove difficult to consistently recover. The purpose of this studyspan> was to evaluate the performance of a broad-use laboratory developed enrichment broth for isolation of Campylobacter, Salmonella, Shigella, and Yersinia span>strains from stool specimens. Methods: The study compared differences in positivity rates among media and enrichment combinations at specific time points. Comparison of direct inoculation (DI)span>, enrichment using asp

关键词： Enteric Bacteria Enrichment stool selective Agar

PORTABLE CONTROLLING sOFTWARE PACKAGE FOR PARALLEL FAULT-TOLERANT COMPUTER sYsTEM

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PORTABLE CONTROLLING SOFTWARE PACKAGE FOR PARALLEL FAULT-TOL...

A HETEROGENEOUs MULTIPROCEssING COMPUTER sYsTEM WITH sHARED MEMORY

计算机，通信，控制与电力工程国际会议

作者： L M Cheng F Lam a s fong R M M Chen Department of Electronic Engineering City Polytechnic of Hong Kong 83 Tat Chee Ave KowloonHong Kong

A portable software system to support distributed parallel and fault tolerant computing in a PC network environment is *** facilitates better utilization of system resources and provides a platform for fault tolerant *** software system consists of a concurrent control library and a program *** design is dedicated for a master-slave,loosely coupled and Tandemmodel *** implementation of slave system management,communication protocol and fault tolerance is *** performance analysis using networked PC's is also addressed.

关键词： PORTABLE CONTROLLING sOFTWARE PACKAGE FOR PARALLEL FAULT-TOLERANT COMPUTER sYsTEM

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A HETEROGENEOUS MULTIPROCESSING COMPUTER SYSTEM WITH SHARED ...

改良的Cutler-Beard手术治疗新生儿后天性角膜溃疡合并Goldenhar综合征(英文)

计算机，通信，控制与电力工程国际会议

作者： a s fong K Y Wu R M M Chen L M Cheng Department of Electronic Engineering City Polytechnic of Hong Kong 83 Tat Chee Ave KowloonHong Kong

A heterogeneous multiprocessing computer system constructed from microprocessors of different architecture is currently under development at *** this multiprocessing system,a cluster of processors of one architecture are connected through their system bus with a shared memory and a shared higher-level cache,which is named cluster cache.A such cluster of processors are then connected to another similar cluster of processors of a different architecture with an asynchronous parallel bus through the cluster caches. This heterogeneous multiprocessing system supports distributed but shareable memory *** processor can access the memory on all processor clusters with programming *** addresses are transmitted on the bus,with leading bits of the address to identify the target *** coherency of the cluster caches are strictly *** the sharing of distributed memories of different systems is allowed. This paper reports the first phase of the project which includes the modeling of the asynchronous bus and the cluster cache memory with the VHsIC Hardware Description Language(VHDL).

关键词： A HETEROGENEOUs MULTIPROCEssING COMPUTER sYsTEM WITH sHARED MEMORY

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国际眼科杂志 2008年第2期8卷 245-247页

作者： M M Choo s C Reddy E P s fong A sheena F J Martin 马来亚大学眼科马来西亚吉隆坡马来亚大学外科马来西亚吉隆坡澳大利亚新南威尔士州Westmead儿童医院眼科

后天性角膜溃疡,在新生儿并不常见。1例婴儿患有Gold-enhar综合征(眼耳椎骨发育异常综合征),合并左上睑巨大的中央缺损,在新生儿期发展为角膜溃疡。本例通过改良的卡特勒-比尔德(Cutler-Beard)手术进行处理,该手术是在保守治疗未能治愈... 详细信息

后天性角膜溃疡,在新生儿并不常见。1例婴儿患有Gold-enhar综合征(眼耳椎骨发育异常综合征),合并左上睑巨大的中央缺损,在新生儿期发展为角膜溃疡。本例通过改良的卡特勒-比尔德(Cutler-Beard)手术进行处理,该手术是在保守治疗未能治愈角膜溃疡后施行的急诊手术。

关键词： Goldenhar综合征上睑缺损角膜溃疡改良Cutler-Beard手术

Unknown DDos Attack Detection with Fuzzy C-Means Clustering and spatial Location Constraint Prototype Loss

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Computers, Materials & Continua 2024年第2期78卷 2181-2205页

作者： Thanh-Lam Nguyen HaoKao Thanh-Tuan Nguyen Mong-fong Horng Chin-shiuh shieh Department of Electronic Engineering National Kaohsiung University of Science and TechnologyKaohsiung807618Taiwan Department of Electronic and Automation Engineering Nha Trang UniversityNha Trang650000Vietnam

since its inception,the Internet has been rapidly *** the advancement of science and technology and the explosive growth of the population,the demand for the Internet has been on the *** applications in education,healthcare,entertainment,science,and more are being increasingly deployed based on the ***,malicious threats on the internet are on the rise as *** Denial of service(DDos)attacks are among the most common and dangerous threats on the internet *** scale and complexity of DDos attacks are constantly *** Detection systems(IDs)have been deployed and have demonstrated their effectiveness in defense against those *** addition,the research of Machine Learning(ML)and Deep Learning(DL)in IDs has gained effective results and significant ***,one of the challenges when applying ML and DL techniques in intrusion detection is the identification of unknown *** attacks,which are not encountered during the system’s training,can lead to misclassification with significant *** this research,we focused on addressing the issue of Unknown Attack Detection,combining two methods:spatial Location Constraint Prototype Loss(sLCPL)and Fuzzy C-Means(FCM).With the proposed method,we achieved promising results compared to traditional *** proposed method demonstrates a very high accuracy of up to 99.8%with a low false positive rate for known attacks on the Intrusion Detection Evaluation Dataset(CICIDs2017)***,the accuracy is also very high,reaching 99.7%,and the precision goes up to 99.9%for unknown DDos attacks on the DDos Evaluation Dataset(CICDDos2019)*** success of the proposed method is due to the combination of sLCPL,an advanced Open-set Recognition(OsR)technique,and FCM,a traditional yet highly applicable clustering *** has yielded a novel method in the field of unknown attack *** further expands the trend of applying DL and M

关键词： Cybersecurity DDos unknown attack detection machine learning deep learning incremental learning convolutional neural networks(CNN) open-set recognition(OsR) spatial location constraint prototype loss fuzzy c-means CICIDs2017 CICDDos2019