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SRMD:Sparse Random Mode Decomposition

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Communications on Applied Mathematics and Computation 2024年第2期6卷 879-906页

作者： Nicholas richardson Hayden Schaeffer Giang Tran University of Waterloo WaterlooONCanada University of British Columbia VancouverBCCanada University of California Los AngelesCAUSA

Signal decomposition and multiscale signal analysis provide many useful tools for timefrequency *** proposed a random feature method for analyzing time-series data by constructing a sparse approximation to the *** randomization is both in the time window locations and the frequency sampling,which lowers the overall sampling and computational *** sparsification of the spectrogram leads to a sharp separation between time-frequency clusters which makes it easier to identify intrinsic modes,and thus leads to a new data-driven mode *** applications include signal representation,outlier removal,and mode *** benchmark tests,we show that our approach outperforms other state-of-the-art decomposition methods.

关键词： Sparse random features Signal decomposition Short-time Fourier transform

How do neurons age?A focused review on the aging of the microtubular cytoskeleton

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Neural Regeneration Research 2024年第9期19卷 1899-1907页

作者： Brad richardson Thomas Goedert Shmma Quraishe Katrin Deinhardt Amritpal Mudher School of Biological Sciences University of SouthamptonSouthamptonUK Institute of Developmental and Regenerative Medicine University of OxfordOxfordUK

Aging is the leading risk factor for Alzheimer’s disease and other neurodegenerative diseases. We now understand that a breakdown in the neuronal cytoskeleton, mainly underpinned by protein modifications leading to the destabilization of microtubules, is central to the pathogenesis of Alzheimer’s disease. This is accompanied by morphological defects across the somatodendritic compartment, axon, and synapse. However, knowledge of what occurs to the microtubule cytoskeleton and morphology of the neuron during physiological aging is comparatively poor. Several recent studies have suggested that there is an age-related increase in the phosphorylation of the key microtubule stabilizing protein tau, a modification, which is known to destabilize the cytoskeleton in Alzheimer’s disease. This indicates that the cytoskeleton and potentially other neuronal structures reliant on the cytoskeleton become functionally compromised during normal physiological aging. The current literature shows age-related reductions in synaptic spine density and shifts in synaptic spine conformation which might explain age-related synaptic functional deficits. However, knowledge of what occurs to the microtubular and actin cytoskeleton, with increasing age is extremely limited. When considering the somatodendritic compartment, a regression in dendrites and loss of dendritic length and volume is reported whilst a reduction in soma volume/size is often seen. However, research into cytoskeletal change is limited to a handful of studies demonstrating reductions in and mislocalizations of microtubule-associated proteins with just one study directly exploring the integrity of the microtubules. In the axon, an increase in axonal diameter and age-related appearance of swellings is reported but like the dendrites, just one study investigates the microtubules directly with others reporting loss or mislocalization of microtubule-associated proteins. Though these are the general trends reported, there are clea

关键词： age-related changes aging cytoskeleton microtubules neuronal morphology

How to fill the biodiversity data gap:Is it better to invest in fieldwork or curation?

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plant Diversity 2024年第1期46卷 39-48页

作者： Carlos A.Vargas Marius Bottin Tiina Sarkinen James E.richardson Marcela Celis Boris Villanueva Adriana Sanchez programa de Biología Facultad de Ciencias NaturalesUniversidad del RosarioBogotaD.C.Colombia Subdireccion Científica Jardín Botanico de Bogota“Jose Celestino Mutis”BogotaD.C.Colombia Independent Researcher BogotaD.C.Colombia Tropical Diversity Section Royal Botanic Garden EdinburghUK School of Biological Earth and Environmental SciencesUniversity College CorkCorkIreland Departamento de Química y Biología Universidad del NorteKm.5 Vía Puerto ColombiaArea Metropolitana de Barranquilla 081007Colombia

Data gaps and biases are two important issues that affect the quality of biodiversity information and downstream *** how best to fill existing gaps and account for biases is necessary to improve our current information most *** current main approaches for obtaining and improving data include(1)curation of biological collections,and(2)***,the comparative effectiveness of these approaches in improving biodiversity data remains little *** used the Flora de Bogota project to study the magnitude of change in species richness,spatial coverage,and sample coverage of plant records based on curation versus *** process of curation resulted in a decrease in species richness(synonym and error removal),but it significantly increased the number of records per *** contributed to a slight increase in species richness,via accumulation of new ***,curation led to increases in spatial coverage,species observed by locality,the number of plant records by species,and localities by species compared to ***,curationwas more efficient in producing new information compared to fieldwork,mainly because of the large number of records available in *** recommend intensive curatorial work as the first step in increasing biodiversity data quality and quantity,to identify bias and gaps at the regional scale that can then be targeted with *** stepwise strategy would enable fieldwork to be planned more costeffectively given the limited resources for biodiversity exploration and characterization.

关键词： Colombia Flora de Bogota Sample coverage Species richness Tropical Andes

Mezigdomide联合地塞米松治疗难治性多发性骨髓瘤患者的临床研究

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中国临床药理学杂志 2023年第20期39卷 2914-2914页

作者： richardson p G 戴荣源

美国丹娜-法伯癌症研究所richardson团队研究了Mezigdomide联合地塞米松治疗复发、难治性多发性骨髓瘤患者的临床疗效与安全性。在这项临床1~2期研究中,研究团队给予对复发和难治性骨髓瘤患者口服.Mezigdomide联合地塞米松。

关键词：癌症研究所骨髓瘤患者难治性多发性骨髓瘤地塞米松治疗临床疗效与安全性团队研究研究团队复发

Assessing Watershed Vulnerability in Bernalillo County, New Mexico Using GIS-Based Fuzzy Inference

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Journal of Water Resource and protection 2019年第2期11卷 99-121页

作者： Clinton p. richardson Kofi Amankwatia Department of Civil and Environmental Engineering New Mexico Tech Socorro NM USA Application Systems Analyst City of Eugene Eugene

Watershed vulnerability was assessed for Bernalillo County, New Mexico using a multi-criteria Fuzzy Inference System (FIS) implemented in a Geographic Information System (GIS). A vulnerability map was produced by means of a weighted overlay analysis that combined soil erosion and infiltration maps derived from the FIS methodology. Five vulnerability classes were stipulated in the model: not vulnerable (N), slightly vulnerable (SV), moderately vulnerable (MV), highly vulnerable (HV), and extremely vulnerable (EV). The results indicate that about 88% of the study area is susceptible to slight (SV) to moderate vulnerability (MV), with 11% of the area subject to experience high or extreme vulnerability (HV/EV). For land use and land cover (LULC) classifications, shrub land was identified to experience the most vulnerability. Weighted overlay output compared similarly with the results predicted by Revised Universal Soil Loss Equation (RUSLE) model with the exception of the not vulnerable (N) class. The eastern portion of the county was identified as most vulnerable due to its high slope and high precipitation. Herein, structural stormwater control measures (SCMs) may be viable for managing runoff and sediment transport offsite. This multi-criteria FIS/GIS approach can provide useful information to guide decision makers in selection of suitable structural and non-structural SCMs for the arid Southwest.

关键词： Stormwater Control Measures Fuzzy Inference System Multi-Criteria Decision Support Systems Geographic Information System

Assessment of CO_(2)storage prospect based on physical properties of Rio Bonito Formation rock units

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Energy Geoscience 2024年第1期5卷 321-330页

作者： richardson M.Abraham-A Stephanie San Martín Cañas Isabella F.S.Miranda Colombo C.G.Tassinari Institute of Energy and Environment(IEE) University of São Paulo(USP)Brazil Research Centre for Greenhouse Gas Innovation(RCGI) University of Sãao Paulo(USP)Brazil

The physical properties of the rock units associated with the Rio Bonito Formation are presented in this study with the focus on modelling reservoir quality based on petrophysics-derived parameters to evaluate CO_(2)storage *** involves the modelling of the reservoir depths,thicknesses,flow zone indicators(FZI),and effective permeability(Keff)and presenting the CO_(2)storage efficiency factors peculiar to the rock units of the study *** results presented by this study for the stated objectives are not quite common in the *** values range from 200 mD to higher than 2000 mD,and FZI values are generally above 1.0 mm and up to 13.0 mm within the portions covered by the drilled *** sandstone units recorded are up to 20 m thick in some *** Keff and FZI models indicate the sandstone reservoirs as permeable units to support the injection and circulation of CO_(2)within the potential reservoir units of the Rio Bonio Formation across São paulo *** from some points in the southeastern part of the study location,where the Rio Bonito are delineated at depths less than 800 m(minimum CO_(2)storage depth based on best practices),other portions are deeper,ranging from 950 m to 3500 ***-bedded layers will affect the integrity of the rocks as CO_(2)storage tanks or reservoir seals/traps/overburden within the *** bed thicknesses are up to 20 m in some ***,hybrid CO_(2)reservoir units are feasible,especially in portions where thin siltstone layers are sandwiched between sandstone units to provide considerable thicknesses based on CO_(2)storage *** current study shows that useable areas considering reservoir thickness,depth,and other physical qualities will significantly control the CO_(2)storage efficiency of the study *** studies featuring a detailed geophysical exploration of the site to confirm the availability and saturations of preexisting fluid(hydrocarbon and water)are encouraged

关键词： Rio Bonito Effective permeability Fluid transmissibility CO_(2)storage prospect Reservoir quality Overburden integrity Flow zones

Evaluating Watershed Vulnerability in Bernalillo County, New Mexico Using Expert Testimony, Fuzzy Analytic Hierarchy process, and GIS

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Journal of Water Resource and protection 2019年第7期11卷 866-885页

作者： Tracy Sadler Clinton p. richardson phillip Miller Department of Civil and Environmental Engineering New Mexico Tech Socorro NM USA New Mexico Bureau of Geology & Mineral Resources New Mexico Tech Socorro NM USA

Geographic Information System (GIS) software was used to create a watershed vulnerability model for Bernalillo County, New Mexico. Watershed vulnerability was investigated as a function of soil erosion and infiltration criteria: precipitation, land slope, soil erodibility (K-factor), vegetation cover (NDVI), land use, drainage density, saturated hydraulic conductivity, and hydrologic soil group. Respective criteria weights were derived using a Fuzzy Analytic Hierarchy process (FAHp) supported by expert opinion. A survey of 10 experts, representing New Mexico Institute of Mining and Technology (NMT), the New Mexico Bureau of Geology and Mineral Resources (NMBGMR), and the United States Geologic Survey (USGS), provided model input data for an integrated pair-wise comparison matrix for soil erosion and for infiltration. Individual criteria weights were determined by decomposing the respective fuzzy synthetic extent matrix using the centroid method. GIS layers were then combined based on criteria weights to produce maps of soil erosion potential and infiltration potential. A composite watershed vulnerability map was generated by equal weighting of each input map. Model results were categorized into five vulnerability categories: not vulnerable (N), slightly vulnerable (SV), moderately vulnerable (MV), highly vulnerable (HV), and extremely vulnerable (EV). The resulting FAHp/GIS model was used to generate a watershed vulnerability map of discrete areas in Bernalillo County, which may be vulnerable to stormwater run-off events and soil erosion. Such high volume run-off events can cause erosion damage to property and infrastructure. Alternatively, in areas near urban development, stormwater run-off may contribute non-point-source pollutant contamination of New Mexico’s surface water resources. The most problematic areas in Bernalillo County are present in the Eastern and Northwestern portions. However, less than 1% of the total area lies within the lowest and highest vulne

关键词： Stormwater Control Measures Fuzzy Analytic Hierarchy process (FAHp) Multi-Criteria Decision Support Systems Geographic Information System Watershed Vulnerability

Tuning electronic properties of cobalt phthalocyanines for oxygen reduction and evolution reactions

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Science China Chemistry 2024年第1期67卷 398-407页

作者： Jianlin Jiang Zhen Liu Shuaijun pan Xinnian Xia Bing Qin Yang Hu Xuxu Wang Jiamin Lan Yu Gu Encai Ou Weijian Xu Joseph J.richardson Rui Guo SINOpEC Research Institute of petroleum processing Co. Ltd.Beijing 100083China College of Chemistry and Chemical Engineering Hunan UniversityChangsha 410082China College of Chemistry and Materials Science Hunan Agricultural UniversityChangsha 410128China Department of Chemical Engineering The University of MelbourneParkville 3010Australia College of Environmental Science and Engineering Hunan UniversityChangsha 410082China School of Engineering RMIT UniversityMelbourneVictoria 3001Australia

Metal–phthalocyanines are a class of catalytically active materials promising in energy conversion and storage fields(e.g.,electrocatalysis).However,understanding and controlling the electrochemical properties in metal-phthalocyanine systems is ***,we elucidate the electrocatalytic origins of a series of cobalt-phthalocyanine molecular catalysts and finetune their electronic properties at the atomic level,both experimentally and *** interactions between the cobalt center and the local coordination environment are regulated by introducing either electron-donating or electron-withdrawing groups on the phthalocyanine ligand,and the spin-orbit splitting of cobalt is increased by~0.15 eV compared with the nonsubstituted ***,the aminated cobalt phthalocyanine-based electrocatalysts exhibit low free energies in the ratedetermining steps of the oxygen reduction(-1.68 eV)and oxygen evolution reactions(0.37 eV).This contributes to the high electrocatalytic activity(e.g.,a halfwave potential of 0.84 V and an overpotential of 0.30 V at 10 mAcm^(-2)),featuring a high selectivity of a four-electron pathway(i.e.,a negligible by-product of hydrogen peroxide).These catalysts also exhibit exceptional kinetic current density(Tafel slope of 100 mV dec^(-1))in oxygen reduction reactions,in addition to a superior power density(158 mWcm^(-2))and a high cycling stability(>1,300 cycles)in Zn-air batteries,outperforming the commercial pt/C and/or RuO2counterparts.

关键词： interfacial wettability molecular catalysts carbon nanotubes density functional theory electrochemistry

Hydrocarbon indication in Rio Bonito Formation sandstone:Implication for CO_(2)storage in São paulo,Brazil

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Energy Geoscience 2024年第1期5卷 331-341页

作者： richardson M.Abraham-A Haline V.Rocha Saulo B.de Oliveira Colombo C.G.Tassinarri Orlando C.da Silva Institute of Energy and Environment University of São PauloSão PauloBrazil Research Centre for Greenhouse Gas Innovation University of São PauloSão PauloBrazil

São paulo State has witnessed CO_(2)storage-based investigations considering the availability of suitable geologic structures and proximity to primary CO_(2)source sinks related to bioenergy and carbon capture and storage(BECCS)*** current study presents the hydrocarbon viability evaluations and CO_(2)storage prospects,focusing on the sandstone units of the Rio Bonito *** objective is to apply petrophysical evaluations with geochemical inputs in predicting future hydrocarbon(gas)production to boost CO_(2)storage within the study *** study used data from eleven wells with associated wireline logs(gamma ray,resistivity,density,neutron,and sonic)to predict potential hydrocarbon accumulation and fluid mobility in the investigated *** samples(shale and carbonate)obtained from depths>200 m within the study location have shown bitumen *** geochemistry data of the Rio Bonito Formation shale beds suggest they are potential hydrocarbon source rocks and could have contributed to the gas accumulations within the sandstone *** drilled well data,e.g.,CB-1-Sp and TI-1-Sp,show hydrocarbon(gas)presence based on the typical resistivity and the combined neutron-density responses at depths up to 3400 m,indicating the possibility of other hydrocarbon members apart from the heavy oil(bitumen)observed from the near-surface rocks *** the three-dimensional(3-D)model,the free fluid indicator(FFI)is more significant towards the southwest and southeast of the area with deeper depths of occurrence,indicating portions with reasonable hydrocarbon recovery rates and good prospects for CO_(2)injection,circulation and permanent ***,future studies based on contemporary datasets are required to establish the hydrocarbon viability further,foster gas production events,and enhance CO_(2)storage possibilities within the region.

关键词： paranáBasin Hydrocarbon indication Sandstone reservoirs Rio Bonito Formation CO_(2)storage Hydrocarbon recovery factor Fluid injection rate