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Diet and microbiome in the beginning of the sequence of gut inflammation

World Journal of Clinical Cases 2021年第36期9卷 11122-11147页

作者： Daniel Ceballos a hernández-camba Laura Ramos Department of Gastroenterology Hospital Universitario de Gran Canaria Doctor NegrinLas Palmas 35019CanariasSpain Department of Gastroenterology Hospital Universitario Nuestra Señora de La CandelariaSanta Cruz de Tenerife 38010CanariasSpain Department of Gastroenterology Hospital Universitario de CanariasSan Cristóbal de La Laguna 38320CanariasSpain

Inflammatory bowel disease(IBD)is a chronic inflammatory condition of the gastrointestinal tract due,at least partially,to an aberrant and excessive mucosal immune response to gut bacteria in genetically-predisposed individuals under certain environmental *** incidence of IBD is rising in western and newly industrialized countries,paralleling the increase of westernized dietary patterns,through new antigens,epithelial function and permeability,epigenetic mechanisms(e.g.,DNA methylation),and alteration of the gut *** in the composition and functionality of the gut microbiome(including bacteria,viruses and fungi)seems to be a nuclear pathogenic *** microbiome itself is dynamic,and the changes in food quality,dietary habits,living conditions and hygiene of these western societies,could interact in a complex manner as modulators of dysbiosis,thereby influencing the activation of immune cells’promoting *** microbiome produces diverse small molecules via several metabolic ways,with the fiber-derived short-chain fatty acids(i.e.,butyrate)as main elements and having anti-inflammatory *** metabolites and some micronutrients of the diet(i.e.,vitamins,folic acid,beta carotene and trace elements)are regulators of innate and adaptive intestinal immune *** excessive and unhealthy consumption of sugar,animal fat and a low-vegetable and-fiber diet are risk factors for IBD ***,metabolism of nutrients in intestinal epithelium and in gut microbiota is altered by inflammation,changing the demand for nutrients needed for *** role of food and a reduced gut microbial diversity in causing IBD might also have a prophylactic or therapeutic role for *** relationship between dietary intake,symptoms,and bowel inflammation could lead to dietary and lifestyle recommendations,including diets with abundant fruits,vegetables,olive oil and oily fish,which have anti-inflammatory effects and could pre

关键词： Diet Microbiome Inflammatory bowel disease Pathogenia

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SYNCHRONOUS COMMUNICATION IN PLM ENVIRONMENTS USING ANNOTATED CAD MODELS

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Journal of Systems Science and Systems Engineering 2016年第2期25卷 142-158页

作者： Jorge D. camba Manuel Contero Gustavo Salvador-Herranz Raquel Plumed College of Architecture University of Houston Houston TX USA I3BH Universitat Politkenica de Valkncia Valencia Spain Depto. de Expresion Grafica Proyectos y Urbanismo Universidad CEU Cardenal Herrera Valencia Spain Depto. de Ingenierla Mecanica y Construccian Universitat Jaume I Castellon Spain

The connection of resources, data, and knowledge through communication technology plays a vital role in current collaborative design methodologies and Product Lifecycle Management （PLM） systems, as these elements act as channels for information and meaning. Despite significant advances in the area of PLM, most communication tools are used as separate services that are disconnected from existing development environments. Consequently, during a communication session, the specific elements being discussed are usually not linked to the context of the discussion, which may result in important information getting lost or becoming difficult to access. In this paper, we present a method to add synchronous communication functionality to a PLM system based on annotated information embedded in the CAD model. This approach provides users a communication channel that is built directly into the CAD interface and is valuable when individuals need to be contacted regarding the annotated aspects of a CAD model. We present the architecture of a new system and its integration with existing PLM systems, and describe the implementation details of an annotation-based video conferencing module for a commercial CAD application.

关键词： Collaborative design PLM design communication CAD integration videoconferencing

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Acoustic contamination assessment during the transition between the COVID-19 restrictions and reactivation:A exploratory analysis in Guayaquil

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Geography and Sustainability 2023年第2期4卷 138-149页

作者： Andrés Velastegui-Montoya Geancarlo Guerrero-Cabrera Sandra Gonzalez-camba Yadira Jaramillo-Lindao Ricardo Murillo-Portillo J.Hidalgo-Crespo Luis Encalada-Abarca Centro de Investigación y Proyectos Aplicados a las Ciencias de la Tierra(CIPAT) ESPOL Polytechnic UniversityP.O.Box 09-01-5863GuayaquilEcuador Facultad de Ingeniería en Ciencias de la Tierra(FICT) ESPOL Polytechnic UniversityP.O.Box 09-01-5863GuayaquilEcuador Geoscience Institute Federal University of Pará66075-110BelémBrazil Facultad de Ciencias Naturales y Matemáticas(FCNM) ESPOL Polytechnic UniversityP.O.Box 09-01-5863GuayaquilEcuador Sciences pour la Conception l’Optimisation et la Production(G-SCOP)Centre National de la Recherche Scientifique(CNRS)UniversitéGrenoble Alpes38000GrenobleFrance Facultad de Ingeniería Industrial Universidad de Guayaquil090150GuayaquilEcuador Centre of Geographical Studies Institute of Geography and Spatial PlanningUniversity of Lisbon1600-276LisbonPortugal Universidad Espíritu Santo SamborondónEcuador

Noise pollution is becoming a critical health risk for city *** 2020,the COVID-19 pandemic forced many cities to implement several mobility *** restrictions changed human activity patterns and decreased the noise levels and noise pollution that often affect urban *** the number of infections decreased,so did the outdoor activities,influencing the population’s perception of *** paper aims to evaluate the changes in noise levels associated with mobility restrictions between 2020 and 2021 in Guayaquil,*** study used crowdsourcing with the help of smartphones and mobile applications to collect geo-referenced environmental noise *** data was used to generate noise maps in different time ***,noise level maps were created using GIS-based tools to identify the urban areas that experienced the highest noise level variation during the study *** results show that the most significant noise increase occurred at ***,when analyzing noise level changes in different urban areas,the western area of Guayaquil was the one that experienced the most significant noise level *** inform the perception of noise pollution and could potentially serve as a reference for decision-makers during the proposal of public policies that ensure a better quality of life for its citizens.

关键词： Acoustic contamination Crowdsourcing Data scrubbing Kriging Noise map

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