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Financial Innovation 2023年第1期9卷 1-18页

作者： Joshua Dzankar Zoaka Hasan gungor Department of Economics Faculty of Business and EconomicsEastern Mediterranean UniversityFamagustaNorth Cyprus

This study aims to shed light on the effects of financial development and accumula-tion of capital on the productivity of labor in the sub-Sahara African region within the period of 1990–*** this work,we used the(dynamic)common correlated effects estimator-mean group and additional techniques such as cross-section autoregressive distributed lag to calibrate the sample into the African subregion to ensure *** findings reveal that financial progress in the region over time leads to an increase in productivity of labor and also the accumulation of ***,financial markets have a progressive impact on the productivity of labor within sub-Saharan African *** extend the very limited literature on the nexus between financial development and labor productivity by incorporating capital accumulation into our model which has not been previously studied.

关键词： Productivity of labor Financial development CS-ARDL Capital accumulation Sub-Saharan Africa

Peripapillary and macular vascular densities in healthy,ocular hypertensive,and different stages of glaucomatous eyes

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International Journal of Ophthalmology(English edition) 2023年第12期16卷 2018-2026页

作者： Caner Ozturk Sirel Gur gungor Umit Eksioglu Almila Sarıgul Sezenoz Meric Colak Comparison of vascular densities in glaucoma patients 1Department of Ophthalmology Minister of Health Hitit University Erol Olcok Education and Research HospitalCorum 19030Turkey Department of Ophthalmology Baskent UniversityFaculty of MedicineAnkara 06170Turkey Department of Biostatistics Baskent UniversityFaculty of MedicineAnkara 06300Turkey

AIM:To investigate vascular changes in different stages of glaucoma and to evaluate the role of optical coherence tomography angiography(OCTA)in the early diagnosis of ***:Glaucoma patients and healthy controls(n=29 eyes)were investigated in this cross-sectional comparative *** patients were grouped as ocular hypertension(n=44 eyes),preperimetric glaucoma(PPG;n=32 eyes),early glaucoma(EG;n=35 eyes),moderate stage glaucoma(MG;n=36 eyes),and advanced glaucoma(AG;n=35 eyes).Peripapillary and macular vascular densities(VDs)of all participants were compared and correlations of VDs and retinal nerve fiber layer thickness(RNFLT),ganglion cell analysis(GCA),and visual field(VF)tests were *** under the receiver operation characteristic curves(AUC)of the peripapillary and macular VD parameters were ***:VD values decreased with the progression of *** peripapillary and macular VD parameters of PPG and EG groups were lower than healthy controls(P<0.001).There was no significant difference in RNFLT between the PPG and EG groups,but most peripapillary and macular VDs were found to be lower in EG group than in PPG group(P<0.05).In most disease group,VDs were significantly correlated with OCT parameters(P<0.001)and VF index(P<0.05).There were no significant correlations between VF and RNFLT indices in the AG group,but significant correlations were found between VF and VD values(P<0.05).AUC for discriminating between healthy and glaucomatous eyes were highest in whole image peripapillary VD(AUC:0.865,0.929,and 0.986,respectively in EG,MG,and AG groups).CONCLUSION:OCTA can be used in the early diagnosis of glaucoma and can be useful in follow-up of the advanced *** cases where limitations or suspicions in structural and functional tests are present,OCTA can be used as a supportive diagnostic test,both in EG and AG.

关键词： glaucoma optical coherence tomography angiography vascular density early diagnosis

Effects of alloying elements and thermomechanical process on the mechanical and corrosion properties of biodegradable Mg alloys

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Journal of Magnesium and Alloys 2021年第1期9卷 241-253页

作者： A.gungor A.Incesu Metallurgical and Materials Engineering Karabuk University78050 KarabukTurkey TOBB Tech.Sciences Vocational School Karabuk University78050 KarabukTurkey

In this study,four different Mg-Zn-Ca-Mn alloys were produced using gravity die casting *** content was kept constant in all alloys,while Zn and Ca were added in two different *** heat treatment was applied to all cast alloys and a specimen from each homogenized alloy was hot ***,mechanical properties,and corrosion behavior of the homogenized and hot rolled alloys were investigated as *** results were obtained;grain size decreased significantly with increasing Zn content,Zn promoted Ca 2 Mg 6 Zn 3 phase formation,corrosion resistance increased with increasing Zn/Ca atomic ratio,hot rolling resulted in much higher tensile strength but much lower ductility and *** the homogenized and hot rolled alloys,ZXM300-h alloy(hot rolled ZXM300 alloy)with its 146±2.5 MPa yield strength,229±3.7 MPa tensile strength,%1.6±0.1 elongation and 0.029 mm/*** corrosion rate exhibited the best mechanical properties and corrosion resistance to be used as a biodegradable alloy such as fracture bone plate material.

关键词： Biodegradable Mg alloys Hot rolling

Boldine provides protective effect against nephrotoxicity induced by cisplatin in Wistar rats:Role of oxidative stress,inflammation and caspase-3

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BIOCELL 2022年第9期46卷 2111-2122页

作者： NERGIZ HACER TURGUT HUSEYIN gungor MEHMET EKICI MUMIN ALPER ERDOGAN MEHMET ONDER KARAYIGIT HAKI KARA Department of Pharmacology Faculty of PharmacyIzmir Katip Celebi UniversityIzmir35620Turkey Department of Pharmacology and Toxicology Faculty of Veterinary MedicineCumhuriyet UniversitySivas58140Turkey Department of Physiology Faculty of Veterinary MedicineCumhuriyet UniversitySivas58140Turkey Department of Physiology Faculty of MedicineIzmir Katip Celebi UniversityIzmir35620Turkey Department of Pathology Faculty of Veterinary MedicineCumhuriyet UniversitySivas58140Turkey

Side effects of cisplatin,especially dose-dependent nephrotoxicity,are major factors limiting its use in ***((S)-2,9-dihydroxy-1,10-dimethoxy-aporphine)is a natural alkaloid known for its strong antioxidant activity present in leaves/bark of boldo tree(Peumus boldus Molina),a native tree in ***,we aimed to investigate the nephroprotective effect of boldine and its underlying mechanisms on cisplatin-induced rat renal *** Wistar albino rats divided into 5 groups(Control,Cis,Bold.40,Cis+Bold.20,Cis+Bold.40 groups)were *** received boldine(20 or 40 mg/kg/day),or vehicle(saline)intraperitoneal for 14 days and a single dose cisplatin(7 mg/kg,ip)was applied on the 10th day to induce *** and kidney tissue were weighed to determine kidney *** urea nitrojen(BUN)and creatinine levels,the amount of thiobarbituric acid reactive substances(TBARS,an index of lipid peroxidation),superoxide dismutase(SOD),glutathione peroxidase(GPx)enzyme activities and tumor necrosis factor alpha(TNF-α)levels were measured and histopathologic examination was *** nitric oxide synthase(iNOS)and caspase-3 expressions were detected *** induced by cisplatin was apparent by elevated levels of BUN,creatinine,kidney index,TBARS and TNF-α,and decreased body weight,SOD and GPx enzyme *** with boldine protected the renal function at both boldine doses by fixing the renal damage markers,oxidative stress,caspase-3 and iNOS *** findings supported biochemical *** together these findings indicate that boldine has promising protective effect against cisplatin nephrotoxicity by improving oxidative stress,inflammation,histopathological alterations and by alleviating caspase 3 expression.

关键词： Boldine Caspase-3 Cisplatin nephrotoxicity Inflammation Oxidative stress

Performance evaluation of waste electrical and electronic equipment disassembly layout configurations using simulation

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Frontiers of Environmental Science & Engineering 2017年第5期11卷 65-75页

作者： Ozan Capraz Olcay Polat Askiner gungor Department of Industrial Engineering Naxmk Kemal University Corlu/Tekirdag 59860 Turkey Department of Industrial Engineering Pamukkale University Pamukkale/Denizli 20160 Turkey

Recycling of waste electrical and electronic equipment （WEEE） is crucially important since it handles hazardous waste according to ever tightening laws and regulations and it adds benefits to economy and sustainable environment. Disassembly is one of the most important processes performed during the recovery of WEEE. The overall goal of disassembly is to maximize the retrieval of various metals and plastics contained in WEEE in order to reduce their negative effects on human health and environmental sustainability and to increase economic gains. This study aims to evaluate alternative layout configurations for WEEE disassembly systems （WDS）. In this context, various configurations were compared in terms of pre-defined performance criteria, such as the total number of disassembled WEEE and the total revenue from sales, using simulation models. The results of this study show that the perfomaance of a WDS was significantly affected by output transfer systems along with the specialization of operators on certain types of WEEE.

关键词： WEEE Recovery Disassembly Layout planning Simulation

Giant myxoinflammatory fibroblastic sarcoma with bone invasion:a very rare clinical entity and literature review

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Chinese Journal of Cancer 2014年第8期33卷 406-410页

作者： Guray Togral Murat Arikan Elif Aktas Safak gungor Department of Orthopaedics and Traumatology Oncology Training and Research HospitalVatan caddesi 06200DemetevlerAnkaraTurkey Department of Radiology Oncology Training and Research HospitalVatan caddesi 06200DemetevlerAnkaraTurkey

Myxoinflammatory fibroblastic sarcoma(MIFS) is a rare low-grade, malignant soft tissue tumor that is usually observed in the extremities of adult patients. Magnetic resonance imaging findings for this tumor type have rarely been reported. We report a case involving the distal left femur of a middle-aged man and tumoral invasion of the bone, which, to our knowledge, has been previously described only once. He was treated with distal femoral tumor resection and reconstruction with a modular prosthesis. Histopathologic diagnosis confirmed MIFS. We reviewed literature of the diagnostic imaging and bone invasion findings associated with this tumor type.

关键词：纤维母细胞文献综述浸润肉瘤肿瘤侵袭实体临床巨人

Conformable fractional heat equation with fractional translation symmetry in both time and space

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Chinese Physics B 2023年第4期32卷 125-129页

作者： W S Chung a gungor J Krız B C Lutfuoglu H Hassanabadi Department of Physics and Research Institute of Natural Science College of Natural ScienceGyeongsang National UniversityJinju 660-701Korea Mechanical Engineering Akdeniz UniversityAntalyaTurkey Department of Physics University of Hradec KraloveRokitanskeho 6250003 Hradec KraloveCzech Republic Department of Physics Akdeniz UniversityAntalyaTurkey Faculty of Physics Shahrood University of TechnologyShahroodIran

We investigate the fractional heat equation with fractional translation in both time and position with different fractional *** examples,we consider a rod and anα-disk with an initial constant temperature and discuss... 详细信息

关键词： fractional derivative heat equation conformable symmetry

Ezrin： a regulator of actin microfilaments in ce unctions of the rat testis

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Asian Journal of Andrology 2015年第4期17卷 653-658页

作者： N Ece gungor-Orduer Ciler Celik-Ozenci C Yan Cheng The Mary M. Wohlford Laboratory for Male Contraceptive Research Center for Biomedical Research Population Council New York USA Department of Histology andEmbryology Faculty of Medicine Akdeniz University Antalya Turkey.

Ezrin, radixin, moesin and merlin （ERM） proteins are highly homologous actin-binding proteins that share extensive sequence similarity with each other. These proteins tether integral membrane proteins and their cytoplasmic peripheral proteins （e.g., adaptors, nonreceptor protein kinases and phosphatases） to the microfilaments of actin-based cytoskeleton. Thus, these proteins are crucial to confer integrity of the apical membrane domain and its associated junctional complex, namely the tight junction and the adherens junction. Since ectoplasmic specialization （ES） is an F-actin-rich testis-specific anchoring junction-a highly dynamic ultrastructure in the seminiferous epithelium due to continuous transport of germ cells, in particular spermatids, across the epithelium during the epithelial cycle-it is conceivable that ERM proteins are playing an active role in these events. Although these proteins were first reported almost 25 years and have since been extensively studied in multiple epithelia/endothelia, few reports are found in the literature to examine their role in the actin filament bundles at the ES. Studies have shown that ezrin is also a constituent protein of the actin-based tunneling nanotubes （TNT） also known as intercellular bridges, which are transient cytoplasmic tubular ultrastructures that transport signals, molecules and even organelles between adjacent and distant cells in an epithelium to coordinate cell events that occur across an epithelium. Herein, we critically evaluate recent data on ERM in light of recent findings in the field in particular ezrin regarding its role in actin dynamics at the ES in the testis, illustrating additional studies are warranted to examine its physiological significance in spermatogenesis.

关键词： blood-testis barrier ectoplasmic specialization ezrin spermatogenesis testis

THE HOMOTHETIC MOTIONS IN THE LORENTZ 3-SPACE

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Acta Mathematica Scientia 2006年第4期26卷 711-719页

作者： M.Tosun A.Kucuk M.A.gungor Department of Mathematics Faculty of Arts Sciences Sakarya UniversitySakarya 54187Turkey Department of Mathematics Kocaeli University Kocaeli 41100Turkey

In this article, the properties of the homothetic motions in three-dimensional Lorentz space are investigated. Also, some geometric results between velocity and acceleration vectors of a point in a spatial motion are ... 详细信息

关键词： Homothetic motion space kinematics Lorentzian geometry

The effect on wound healing of pazopanib and bevacizumab compared with corticosteroid in experimental glaucoma filtration surgery

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International Journal of Ophthalmology(English edition) 2018年第12期11卷 1909-1915页

作者： Sabiha gungor Kobat Fatma Ulku Celiker Adile Ferda Dagli Kader Kasar Department of Ophthalmology Elazig Health Sciences University Department of Ophthalmology School of Medicine Firat University Department of Pathology School of Medicine Firat University Department of Ophthalmology Ordu State Hospital

AIM: To compare the effects of bevacizumab and pazopanib with corticosteroids on wound healing after trabeculectomy. METHODS: In the study, 35 New Zealand white rabbits were randomly divided into five groups. Apart from the first group, limbus-based trabeculectomy was performed for the eyes of rabbits. No postoperative treatment was administered for group Ⅰ. Topically administered saline, prednisolone acetate(1%), bevacizumab 5 mg/mL, pazopanib 5 mg/mL for group Ⅱ, Ⅲ, Ⅳ and Ⅴ respectively were applied for groups 6 h daily for 28 d. On day 28 of the experiment, eyes were enucleated and histologically and immunohistochemically ***: The fibroblast counts of groups Ⅳ and Ⅴ were determined to be lower than those of groups Ⅱ and Ⅲ(P0.05). The immunohistochemical staining intensity of fibroblast growth factor β(FGF-β) and vascular endothelial growth factor(VEGF) was determined to be lower in groups Ⅳ and Ⅴ than in groups Ⅱ and Ⅲ(P0.05). The platelet derived growth factor β(PDGF-β) intensity was lower in group Ⅴ than in groups Ⅱ, Ⅲ and Ⅳ(P0.05). CONCLUSION: Bevacizumab and pazopanib might be good alternatives of corticosteroid treatment on delaying wound healing in glaucoma surgery.

关键词： trabeculectomy wound healing corticosteroid bevacizumab pazopanib