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Time to take another Iook at perceived disadvantages of robotic hepatectomy

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Hepatobiliary Surgery and Nutrition 2020年第2期9卷 208-210页

作者： Yasushi hasegawa Hiroyuki Nitta Takeshi Takahara Akira Sasaki Department of Surgery Iwate Medical University School of MedicineMorioka CityIwateJapan

Robotic hepatectomy remains controversial to date,despite continuous advances in the technology and more surgeons gaining experience with the *** et al.(1)recently published an interesting article in Hepatobiliary Surgery and Nutrition,titled"Selecting incision-dominant cases for robotic liver resection:towards outpatient hepatectomy with rapid recovery."The authors evaluated 97 cases of robotically-assisted liver resection(RLR)arguing that it is difficult to reach the superior-posterior liver segments with the straight instruments used in conventional laparoscopic liver resection(LLR).The articulated instruments of the surgical robot are better suited for hepatectomies in these difficult-to-reach areas of the *** concluded that cases where the incision of an open approach would be large and affect recovery results in the highest likelihood of patients benefitting from a robotic *** think that the authors present an interesting perspective by focusing on the strong points of RLR compared to LLR.

关键词： hepatectomy Surgery straight

Determination of the Dzyaloshinskii-Moriya interaction using pattern recognition and machine learning

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npj Computational Materials 2021年第1期7卷 198-204页

作者： Masashi Kawaguchi Kenji Tanabe Keisuke Yamada Takuya Sawa Shun hasegawa Masamitsu Hayashi Yoshinobu Nakatani Department of Physics The University of TokyoTokyo 113-0033Japan Toyota Technological Institute Nagoya 468-8511Japan Department of Chemistry and Biomolecular Science Faculty of EngineeringGifu UniversityGifu 501-1193Japan University of Electro-Communications Tokyo 182-8585Japan

Machine learning is applied to a large number of modern devices that are essential in building an energy-efficient smart *** and face recognition are among the most well-known technologies that make use of such artificial *** materials research,machine learning is adapted to predict materials with certain functionalities,an approach often referred to as materials ***,we show that machine learning can be used to extract material parameters from a single image obtained in *** Dzyaloshinskii–Moriya(DM)interaction and the magnetic anisotropy distribution of thin-film heterostructures,parameters that are critical in developing next-generation storage class magnetic memory technologies,are estimated from a magnetic domain *** simulation is used to generate thousands of random images for training and model validation.A convolutional neural network system is employed as the learning *** DM exchange constant of typical Co-based thin-film heterostructures is studied using the trained system:the estimated values are in good agreement with ***,we show that the system can independently determine the magnetic anisotropy distribution,demonstrating the potential of pattern *** approach can considerably simplify experimental processes and broaden the scope of materials research.

关键词： pattern interaction system

Self-Assembly of TBrPP-Co Molecules on an Ag/Si（111） Surface Studied by Scanning Tunneling Microscopy

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Chinese Physics Letters 2010年第2期27卷 224-227页

作者：李青 Shiro Yamazaki Toyoaki Eguchi 马旭村贾金锋薛其坤 Yukio hasegawa Institute of Physics Chinese Academy of Science Beijing 100190 The Institute for Solid State Physics The University of Tokyo 5-1-5 Kashiwa-no-ha Kashiwa 277-8581 Japan Department of Physics Tsinghua University Beijing 100084

Self-assembly of TBrPP-Co molecules on a Si（111）-√3t×√3 Ag substrate is studied by low-temperature scanning tunneling microscopy. With the same adsorbed amount （0.07 ML）, the molecules deposited by low-temperature evaporation show three kinds of ordered structures whereas those deposited by high-temperature evaporation have size-dependent ordered structures. The distinct differences in the self-assembly structures and in the electron density of states inside the molecule near the Fermi energy demonstrate that the Br atoms of the molecule desorb at the higher evaporation temperature.

关键词： Cold Temperature Timing Time Aging Evaporation Evaporating

Pancreaticoduodenectomy: how to handle a replaced right hepatic artery

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Hepatobiliary Surgery and Nutrition 2023年第2期12卷 280-283页

作者： Junichi Kaneko Akihiko Ichida Yoshikuni Kawaguchi Kiyoshi hasegawa Hepato-Biliary-Pancreatic Surgery Division Department of SurgeryGraduate School of MedicineThe University of TokyoTokyoJapan

Hepatobiliary pancreatic surgeons sometimes encounter an aberrant(or replaced)right hepatic artery(a-RHA,Hiatt types III-VI)during pancreaticoduodenectomy(PD).Arterial flow cutoff to the a-RHA may be associated with a biliary leak or stenosis at the choledocho-jejunostomy and liver ischemia,resulting in ischemic cholangitis,liver abscess,and sepsis(1).

关键词： Pancreaticoduodenectomy(PD) replaced right hepatic artery pancreatic ductal adenocarcinoma(PDAC)

Does laparoscopic resection for colorectal cancer liver metastasis have a long-term oncologic advantage?

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Hepatobiliary Surgery and Nutrition 2021年第2期10卷 246-248页

作者： Yasushi hasegawa Minoru Kitago Yuta Abe Yuko Kitagawa Department of Surgery Keio University School of MedicineTokyoJapan

The long-term advantages of laparoscopic liver resection(LLR)over open liver resection(OLR)for colorectal cancer liver metastasis(CLM)have not been *** et al.(1)recently published an interesting article in the Annals of Surgery,titled“Survival Advantage of Laparoscopic Versus Open Resection for Colorectal Liver Metastases:A Meta-analysis of Individual Patient Data from Randomized Trials and Propensity-score Matched Studies.”The authors performed a meta-analysis of individual participant data from two randomized trials and thirteen propensity score-matched studies that compared long-term outcomes between patients undergoing LLR and OLR for CLM.A total of 1,275 patients who underwent LLR and 1,873 patients who underwent OLR were *** found that LLR was associated with a lower risk of death and concluded that LLR had a long-term survival benefit compared to OLR.

关键词： metastasis Surgery liver

Nanoparticles-based nanochannels assembled on a plastic flexible substrate for label-free immunosensing

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Nano Research 2015年第4期8卷 1180-1188页

作者： Alfredo de la Escosura-Muniz Marisol Espinoza-Castaneda Madoka.hasegawa Laetitia Philippe Arben Merkoci ICN2-Nanobioelectronics & Biosensors Group Institut Catala de Nanociencia i Nanotecnologia Campus UAB 08193 Bellaterra (Barcelona) Spain EMPA Swiss Federal Laboratories for Materials Science and Technology Feuerwerkerstrasse 39 3602Thun Switzerland ICREA-Institucio Catalana de Recerca i Esrudis Avan@ats 08010 Barcelona Spain

A novel, cheap, disposable and single-use nanoparticles-based nanochannel platform assembled on a flexible substrate for label-free immunosensing is pre- sented. This sensing platform is formed by the dip-coating of a homogeneous and assembled monolayer of carboxylated polystyrene nanospheres （PS, 200 and 500 nm-sized） onto the working area of flexible screen-printed indium tin oxide/polyethylene terephthalate （ITO/PET） electrodes. The spaces between the self-assembled nanospheres generate well-ordered nanochannels, with inter-PS particles distances of around 65 and 24 nm respectively. The formed nanochannels are used for the effective immobilization of antibodies and subsequent protein detection based on the monitoring of [Fe（CN）6]^4- flow through diffusion and the decrease in the differential pulse voltammetric signal upon immunocomplex formation. The obtained sensing system is nanochannel-size dependent and allows human immunoglobulin G （IgG）（chosen as a model analyte） to be detected at levels of 580 ng/mL. The system also exhibits an excellent specificity against other proteins present in real samples and shows good performance with a human urine sample. The developed device represents an integrated and simple biodetection system which overcomes many of the limitations of previously reported nanochannels-based approaches and can be extended in the future to several other immuno and DNA detection systems.

关键词： nanochannel dip-coating.electrochemical biosensor label-free immunosensing

Features of hepatocellular carcinoma in cases with autoimmune hepatitis and primary biliary cirrhosis

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World Journal of Gastroenterology 2009年第2期15卷 231-239页

作者： Takuya Watanabe Kenji Soga Haruka Hirono Katsuhiko hasegawa Koichi Shibasaki Hirokazu Kawai Yutaka Aoyagi Department of Internal Medicine and Gastroenterology Medical Hospital The Nippon Dental University School of Life Dentistry at Niigata 1-8 Hamauracho Chu-o-ku Niigata 951-8580 Japan Department of Gastroen-terology Niigata University Graduate School of Medical and Dental Sciences 1-757 Asahimachi Chu-o-ku Niigata 951-8510 Japan

AIM: To characterize the clinical features of hepatocellular carcinoma (HCC) associated with autoimmune liver disease, we critically evaluated the literature on HCC associated with autoimmune hepatitis (AIH) and primary biliary cirrhosis (PBC). METHODS: A systematic review of the literature was conducted using the Japana Centra Revuo Medicina database which produced 38 cases of HCC with AIH (AIH-series) and 50 cases of HCC with PBC (PBC-series). We compared the clinical features of these two sets of patients with the general Japanese HCC population. RESULTS: On average, HCC was more common in men than in women with AIH or PBC. While many patients underwent chemolipiodolization (CL) or transcatheter arterial embolization (TAE) (AIH-series: P = 0.048 (vs operation), P = 0.018 (vs RFA, PEIT); PBC-series: P = 0.027 (vs RFA, PEIT), others refused therapeutic interventions [AIH-series: P = 0.038 (vs RFA, PEIT); PBC-series: P = 0.003 (vs RFA, PEIT)].Liver failure was the primary cause of death among patients in this study, followed by tumor rupture. The survival interval between diagnosis and death was fairly short, averaging 14 ± 12 mo in AIH patients and 8.4 ± 14 mo in PBC patients. CONCLUSION: We demonstrated common clinical features among Japanese cases of HCC arising from AIH and PBC.

关键词： Autoimmune hepatitis Autoimmune liver disease Hepatocellular carcinoma Literature review Primary biliary cirrhosis

PARTICLE-BASED TRANSPARENT FUSED VISUALIZATION APPLIED TO MEDICAL VOLUME DATA

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International Journal of Modeling, Simulation, and Scientific Computing 2013年第S1期4卷 104-114页

作者： KYOKO hasegawa SAORI OJIMA YOSHIYUKI SHIMOKUBO SUSUMU NAKATA KOZABURO HACHIMURA SATOSHI TANAKA College of Information Science and Engineering Ritsumeikan University Noji Higashi 1-1-1 KusatsuShiga525-8577Japan Graduate School of Science and Engineering Ritsumeikan University Noji Higashi 1-1-1 KusatsuShiga525-8577Japan

This paper proposes a method to create 3D fusion images,such as volume–volume,volume–surface,and surface–surface *** method is based on the particle-based rendering,which uses tiny particles as rendering *** method can create natural and comprehensible 3D fusion images simply by merging particles prepared for each element to be ***,the method does not require particle sorting along the line of sight to realize right depth *** apply our method to realize comprehensible visualization of medical volume data.

关键词： Particle-based rendering fused visualization stochastic particle generation.

Effects of Earth's curvature and radial heterogeneity in dislocation studies:Case studies of the 2008 Wenchuan earthquake and the 2004 Sumatra earthquake

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Earthquake Science 2010年第4期23卷 301-308页

作者： Guangyu Fu Wenke Sun Yoichi Fukuda Shanghua Gao Takashi hasegawa Institute of Earthquake Science China Earthquake Administration Beijing 100036 China Department of Geophysics Graduate School of Science Kyoto University Kyoto 606-8502 Japan Laboratory of Computational Geoclynamics Graduate University of Chinese Academy of Sciences Beijing 100049 China

Recently, effects of Earth＇s curvature and radial heterogeneity on coseismic deformations are often investi- gated based on the 2004 Sumatra earthquake. However, such effects are strongly related to earthquake types. As a low dip angle event, the 2004 Sumatra earthquake is not a good seismic case for such a topic since the effects for moderate dip angle events are much bigger. In this study, the half-space and spherical dislocation theories are used, respectively, to calculate co- seismic displacements caused by the 2008 Wenchuan earthquake and the 2004 Sumatra earthquake. Effects of Earth＇s curva- ture and stratification are investigated through the discrepancies of results calculated using the two dislocation theories. Re- sults show that the effects of Earth＇s curvature and stratification for the 2008 Wenchuan earthquake are much larger than those for the 2004 Sumatra earthquake. Ignoring the effects will cause errors up to 100%-200% in far field displacements for a moderate dip angle event like the 2008 Wenchuan earthquake. Such great effects are much bigger than those conclusions of previous studies. Besides, comparison with observations verifies that spherical dislocation theories yield better results than half-space ones in far fields.

关键词： coseismic displacement dislocation theory Earth model