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The role of land use on the local climate and air quality during calm inter-monsoon in a tropical city

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Geoscience Frontiers 2019年第2期10卷 405-415页

作者： M.C.G.Ooi a.chan M.J.Ashfold M.Y.Oozeer K.I.Morris S.S.K.Kong Department of Atmospheric Science "Central University" Department of Civil Engineering University of Nottingham Malaysia Campus School of Environmental and Geographical Sciences University of Nottingham Malaysia Campus Department of Geography and Environmental Management University of Waterloo Center of Excellence for Sustainable Innovation and Research Initiative (CESIRI) Department of Mechanical Engineering Ashesi University College

The modification of land use is known to be a major climate change driver to the local warming and air quality in cities. Despite the reduction of NOx over the years, the Selangor state has captured a higher level of O_3 in year 2011. The measurement result has shown that the surge in O_3 level was attributed to the reduction of NO_x/NMHC ratio. This paper hence attempted to identify the role of land use change from 1999 to 2011 on the ground ozone air quality in the tropical urban conurbation, Greater Kuala Lumpur(GKL), Selangor, Malaysia. With the state-of-the-art chemical weather prediction tool, WRFChem, the external synoptic factors and emission inventory were controlled when comparing the chronological land use changes. The results showed that the urban-induced temperature and wind bias in the tropical region has induced stronger wind to disperse the NO_x and carries the TVOC from the suburban to the downwind urban region. The reduction of NO_x/TVOC has gradually shifted towards the optimum O_3 formation regime in 2011. The formation of highly concentrated ozone becomes more sensitive to the increment of TVOC as the NO_x level reduces in the urban. This highlights the essential involvement of TVOC in the ozone formation in lieu of the NOx reduction in the tropical city, a region with growing emitter of reactive biogenic ozone precursors.

关键词： Land use change Urban Ground ozone TVOC WRF-Chem Tropics

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Multimodal single-cell omics analysis identifies epithelium-immune cell interactions and immune vulnerability associated with sex differences in COVID-19

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Signal Transduction and Targeted Therapy 2021年第8期6卷 2586-2599页

作者： Yuan Hou Yadi Zhou Michaela U.Gack Justin D.Lathia Asha Kallianpur Reena Mehra Timothy a.chan Jae U.Jung Lara Jehi Charis Eng Feixiong Cheng Genomic Medicine Institute Lerner Research InstituteCleveland ClinicClevelandOHUSA Florida Research and Innovation Center Cleveland ClinicPort Saint LucieFLUSA Department of Cardiovascular and Metabolic Science Lerner Research InstituteCleveland ClinicClevelandOHUSA Department of Molecular Medicine Cleveland Clinic Lerner College of MedicineCase Western Reserve UniversityClevelandOHUSA Department of Population and Quantitative Health Sciences Case Western Reserve UniversityClevelandOHUSA Neurological Institute Cleveland ClinicClevelandOHUSA Center for Immunotherapy and Precision Immuno-Oncology Cleveland ClinicClevelandOHUSA Department of Cancer Biology Lerner Research InstituteCleveland ClinicClevelandOHUSA Department of Genetics and Genome Sciences Case Western Reserve University School of MedicineClevelandOHUSA Case Comprehensive Cancer Center Case Western Reserve University School of MedicineClevelandOHUSA

Sex differences in the susceptibility of SARS-CoV-2 infection and severity have been controversial,and the underlying mechanisms of COVID-19 in a sex-specific manner remain *** we inspected sex differences in SARS-CoV-2 infection,hospitalization,admission to the intensive care unit(ICU),sera inflammatory biomarker profiling,and single-cell RNA-sequencing(scRNA-seq)profiles across nasal,bronchoalveolar lavage fluid(BALF),and peripheral blood mononuclear cells(PBMCs)from COVID-19 patients with varying degrees of disease *** propensity score-matching observations revealed that male individuals have a 29%elevated likelihood of SARS-CoV-2 positivity,with a hazard ratio(HR)1.32(95%confidence interval[Cl]1.18-1.48)for hospitalization and HR 1.51(95%Cl 1.24-1.84)for admission to *** from male patients at hospital admission had elevated neutrophil-lymphocyte ratio and elevated expression of inflammatory markers(C-reactive protein and procalcitonin).We found that SARS-CoV-2 entry factors,including ACE2,TMPRSS2,FURIN,and NRP1,have elevated expression in nasal squamous cells from male individuals with moderate and severe *** observed male-biased transcriptional activation in SARS-CoV-2-infected macrophages from BALF and sputum samples,which offers potential molecular mechanism for sex-biased susceptibility to viral ***-cell interaction network analysis reveals potential epithelium-immune cell interactions and immune vulnerability underlying male-elevated disease severity and mortality in ***,monocyte-elevated expression of Toll-like receptor 7{TLR7)and Bruton tyrosine kinase{BTK)is associated with severe outcomes in males with *** summary,these findings provide basis to decipher immune responses underlying sex differences and designing sex-specific targeted interventions and patient care for COVID-19.

关键词： elevated epithelium analysis

舍二求一，任重道远——专访法拉帝集团亚太区代表陈钢

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游艇业 2008年第1期 44-45页

作者： a．chan（采编）陈钢（图）不详 Ferretti Yachts

2008年1月10日．法拉帝游艇公司（Ferretti Yachts）在上海宣布：和记行（集团）有限公司旗下的坚荣控股有限公司正式成为法拉帝豪华游艇中国区总代理．之前该公司在内地南北区各设一个代理商的情况将不复存在。法拉帝游艇公司亚太区总... 详细信息

2008年1月10日．法拉帝游艇公司（Ferretti Yachts）在上海宣布：和记行（集团）有限公司旗下的坚荣控股有限公司正式成为法拉帝豪华游艇中国区总代理．之前该公司在内地南北区各设一个代理商的情况将不复存在。法拉帝游艇公司亚太区总经理Giuseppe Zecchin先生与和记行主席李文辉先生共同表示．双方将紧密合作，为中国客户打造最完美的游艇之梦。本刊记者就此专访了法拉帝集团亚太区代表陈钢．以求解开该公司在内地代理商“舍二求一”的真正原因。

关键词：亚太区豪华游艇陈钢代理商总经理中国法拉帝集团法拉帝游艇公司

Presence of emergency medical physicians in a rural hospital;would it make a difference?

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Presence of emergency medical physicians in a rural hospital...

应对钻井挑战的先进技术和解决方案——为应对钻井产业相关的服务、设备、工具和材料成本的显著提高，必须采用先进高效的技术提高钻井效率

第十一次全国急诊医学学术会议暨中华医学会急诊医学分会成立二十周年庆典

作者： P．P．Y．CHEE K．M．CHUNG A．L．C．LAW a．chan A&E Department St．John Hospital Cheung ChauHong Kong

St. John Hospital (SJH) is a rural hospital in an outlying island of Hong Kong SAR. In the past, the management of patients had been taken care of by doctors without specialist training. Patients were brought to urban hospitals by helicopters or police launches, i.e. CASEVAC, after a brief assessment in SJH. Since 2001, doctors with emergency medicine background began to serve in SJH. In 2004, the first emergency physician was employed to conduct regular clinical audits, mortality & morbidity meetings and trainings to the clinical staff. This study examines whether the involvement of doctors with emergency medicine background has resulted in different CASEVAC activation patterns and patient outcomes.

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世界石油工业 2016年第3期23卷 46-51页

作者： M. J. Jellison a.chan 国民油井华高 Workstrings International 公司

随着钻进速度的大幅提升，与钻井产业相关的服务、设备、工具和材料成本也显著提高，但现有油气井和油气藏产量却在不断下降，因此必须采用先进高效的技术在可控成本下提高钻井效率。从第三代双台肩接头、深水钻井对座放管柱的高抗拉性... 详细信息

随着钻进速度的大幅提升，与钻井产业相关的服务、设备、工具和材料成本也显著提高，但现有油气井和油气藏产量却在不断下降，因此必须采用先进高效的技术在可控成本下提高钻井效率。从第三代双台肩接头、深水钻井对座放管柱的高抗拉性能要求、深水钻井井下摩擦生热造成的钻杆破坏以及酸性环境下全套抗SSC钻柱系统（包括摩擦焊缝）的研究等方面介绍了钻井技术的最新进展，解决了与深水钻井钻柱相关的实际问题，井指出深水钻井中大位移、大斜度和深层油气藏钻井的挑战趋势将持续增加，还需要不断改进和提高钻杆和钴柱构件的性能，并持续探索创新型解决方案以克服油气工业面临的各种挑战。

关键词：深水钻井钻井技术最新进展解决方案

Global collaboration of eye research--personal experience

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International Journal of Ophthalmology(English edition) 2024年第6期17卷 985-990页

作者： Chi-Chao chan Laboratory of Immunology National Eye InstituteNational Institutes of HealthBethesdaMD 20892-1858USA Zhongshan Ophthalmic Center Sun Yat-sen UniversityGuangzhou 5410060Guangdong ProvinceChina

On December 9,2023,I was privileged to be honored and participate in the *** Chao chan Symposium on Global Collaboration of Eye Research as the Global Eye Genetic Consortium(GEGC)session,which was held in the 16th Congress of the Asia-Pacific Vitreo-Retina Society(APVRS)in Hong *** with my talk on“Global collaboration of eye research:personal experience”,other prominent international speakers provided their own perspectives on opportunities for networking,collaboration,and exchange of ideas with global leaders and experts in ophthalmic practice,research,and education.

关键词： speakers collaboration Global

Tetradentate Pt(Ⅱ)complex as a singlet exciton sensitizing host for highly efficient green fluorescent organic light-emitting diodes

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Science China Materials 2024年第8期67卷 2618-2627页

作者： Unhyeok Jo Seung chan Kim chan Hee Ryu Kang Mun Lee Jae-Min Kim Jun Yeob Lee School of Chemical Engineering Sungkyunkwan University2066Seobu-roJangan-guSuwon-siGyeonggi-do 16419Republic of Korea Department of Chemistry Institute for Molecular Science and Fusion TechnologyKangwon National UniversityChuncheonGangwon 24341Republic of Korea Department of Advanced Materials Engineering Chung-Ang University4726Seodong-daeroDaedeok-myeonAnseong-siGyeonggi-do 17546Republic of Korea SKKU Advanced Institute of Nano Technology Sungkyunkwan University2066Seobu-roJangan-guSuwonGyeonggi 16419Republic of Korea SKKU Institute of Energy Science and Technology Sungkyunkwan University2066Seobu-roJangan-guSuwonGyeonggi 16419Republic of Korea

Efficient green fluorescent organic light-emitting diodes were designed with a phosphorescent metal complex as a singlet exciton sensitizing host(SESH)for achieving high efficiency and low efficiency roll-off through exciton and polaron *** Pt(Ⅱ)complex(Pt-Trz)possessing a tetradentate ligand with a bulky blocking group not only suppresses the severe formation of excimer or dimer itself but also transfers radiative excitons to fluorescent dopant *** SESH assisted fluorescence(SESHF)device with Pt-Trz as the host exhibits the maximum external quantum efficiency of 13.3%and a lower efficiency roll-off compared with exciplex host device which is a general approach for harvesting triplet *** exciton dynamics modeling unravels that the SESHF device effectively utilizes triplet excitons in the host by intersystem crossing and resonance energy transfer from the triplet state of the host to the singlet state of the terminal *** quenching rates of the SESHF device are reduced by 11 times for triplet-triplet annihilation and 1.8 times for tripletpolaron annihilation compared with the exciplex device,which demonstrates that Pt-Trz could be a platform to be used as an efficient host for fluorophores.

关键词： singlet annihilation polaron

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多发性硬化病人颈段脊髓弥漫性与局限性病变的1H-MRS

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国际医学放射学杂志 2014年第1期 98-99页

作者： B.Bellenberg M.Busch N.Trampe R.Gold a.chan C.Lukas 袁涛 Department of Radiology and Nuclear Medicine ST.Josef HospitalRuhr University of BochumGurunstr.56444791BochumGermany

目的探讨多发性硬化(MS)病人1.5 T MRI基准检查与随访时颈段脊髓局限性与弥漫性病变氢质子波谱(1H-MRS)、上颈段脊髓定量MRI及T2值测量的差异。方法

关键词：多发性硬化脊髓 MRS 颈段脊髓病变 MRI

Interplay of laser power and pore characteristics in selective laser melting of ZK60 magnesium alloys:A study based on in-situ monitoring and image analysis

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Journal of Magnesium and Alloys 2024年第4期12卷 1346-1366页

作者： Weijie Xie Hau-Chung Man Chi-Wai chan Department of Industrial and Systems Engineering The Hong Kong Polytechnic UniversityHong KongChina School of Mechanical and Aerospace Engineering Queen’s UniversityBelfast BT95AHUK Research Institute for Advanced Manufacturing The Hong Kong Polytechnic UniversityHong KongChina

This study offers significant insights into the multi-physics phenomena of the SLM process and the subsequent porosity characteristics of ZK60 Magnesium(Mg)***-speed in-situ monitoring was employed to visualise process signals in real-time,elucidating the dynamics of melt pools and vapour plumes under varying laser power conditions specifically between 40 W and 60 *** morphological analysis was performed using Scanning-Electron Microscopy(SEM),demonstrating a critical correlation between laser power and pore *** laser power led to increased pore coverage,whereas a denser structure was observed at higher laser *** laser power influence on porosity was further confirmed via Optical Microscopy(OM)conducted on both top and cross-sectional surfaces of the *** increase in laser power resulted in a decrease in pore coverage and pore size,potentially leading to a denser printed part of Mg alloy.X-ray Computed Tomography(XCT)augmented these findings by providing a 3D volumetric representation of the sample internal structure,revealing an inverse relationship between laser power and overall pore *** laser power appeared to favour the formation of interconnected pores,while a reduction in interconnected pores and an increase in isolated pores were observed at higher *** interplay between melt pool size,vapour plume effects,and laser power was found to significantly influence the resulting porosity,indicating a need for effective management of these factors to optimise the SLM process of Mg alloys.

关键词： Selective laser melting(SLM) Magnesium(Mg)alloys Biodegradable implants Porosity In-situ monitoring

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