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Sequencing,annotation and comparative analysis of nine BACs of the giant panda(Ailuropoda melanoleuca)

Science China(Life Sciences) 2010年第1期53卷 107-111页

作者： ZHENG Yang1,2,3.CAI Jing4,LI JianWen3.6,LI Bo3.LIN RunMao3.TIAN Feng3.WANG XiaoLing3.& WANG Jun3.5 1Beijing Institute of Genomics,Chinese Academy of Sciences(CAS),Beijing 100029,China 2College of Life Science,graduate university of Chinese Academy of Sciences,Beijing 100049,China 3.eijing Genomics Institute at Shenzhen,Shenzhen 518083.China 4CAS-Max Planck Junior Research Group on Evolutionary Genomics,State Key Laboratory of Genetic Resources and Evolution,Kunming Institute of Zoology,Chinese Academy of Sciences(CAS),Kunming 650223.China 5Department of Biology,university of Copenhagen,Copenhagen DK-2200,Denmark 6School of Biological Science and Engineering,South China university of Technology,Guangzhou 510006,China Beijing Institute of Genomics Chinese Academy of Sciences (CAS) Beijing China College of Life Science Graduate University of Chinese Academy of Sciences Beijing China Beijing Genomics Institute at Shenzhen Shenzhen China CAS-Max Planck Junior Research Group on Evolutionary Genomics State Key Laboratory of Genetic Resources and Evolution Kunming Institute of Zoology Chinese Academy of Sciences (CAS) Kunming China School of Biological Science and Engineering South China University of Technology Guangzhou China Department of Biology University of Copenhagen Copenhagen Denmark

A 10-fold BAC library for the giant panda was constructed and nine BACs were selected to generate finish *** BACs could be used as a validation resource for the de novo assembly accuracy of the whole genome shotgun sequencing reads of the giant panda newly generated by Illumina GA sequencing *** Sanger sequencing,assembly,annotation and comparative analysis were carried out on the selected BACs of a joint length 878 *** search and de novo prediction methods were used to annotate genes and *** protein coding genes were predicted,seven of which could be functionally *** seven genes have an average gene size of about 41 kb,an average coding size of about 1.2 kb and an average exon number of 6 per ***,seven tRNA genes were *** 27 percent of the BAC sequence is composed of repeats.A phylogenetic tree was constructed using a neighbor-join algorithm across five species,including the giant panda,human,dog,cat and mouse,which reconfirms dog as the most closely related species to the giant *** results provide detailed sequence and structure information for new genes and repeats of the giant panda,which will be helpful for further studies about the giant panda.

关键词： giant panda BAC sequencing assembly annotation evolution

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SQUARE attack on block ciphers with low algebraic degree

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Science China(Information Sciences) 2010年第10期53卷 1988-1995页

作者： SUN Bing 1 , LI RuiLin 1 , QU LongJiang 1,3.& LI Chao 1,2,3.1 Science College of National university of Defense Technology, Changsha 410073. China 2 State Key Laboratory of Information Security, graduate university of Chinese Academy of Sciences, Beijing 100049, China 3.National Mobile Communications Research Laboratory, Southeast university, Nanjing 210096, China 1. Science College of National university of Defense Technology Changsha 410073 China3. National Mobile Communications Research Laboratory Southeast University Nanjing 210096 China2. State Key Laboratory of Information Security Graduate University of Chinese Academy of Sciences Beijing 100049 China

By using an algebraic method, the mathematical foundation of SQUARE attack is studied in this paper. We point out that a SQUARE distinguisher exists if and only if the degree of the polynomial function between n-bit input which is active and n-bit output which is balanced is 2 n-2. And the algebraic method can also be used to determine the property of a balanced set after passed through a nonlinear S-box, by which in some cases we can find a SQUARE distinguisher with more rounds. The validity of SQUARE attack and the influence of the choice of S-box are also studied. If the round function of a Feistel cipher has a low algebraic degree, a SQUARE attack cannot recover the right keys in some special cases. However, SQUARE attack on SPN ciphers always holds. The relations among SQUARE attack and some other cryptanalytic method are studied, showing that if a cipher is breakable by SQUARE attack, then it is also breakable by the interpolation attack.

关键词： SQUARE attack interpolation attack integral attack block cipher

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Teleconnection between the Indian summer monsoon onset and the Meiyu over the Yangtze River Valley

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Science China Earth Sciences 2008年第7期51卷 1021-1035页

作者： LIU YunYun1,2,3.& DING YiHui2 1 Chinese Academy of Meteorological Sciences, Beijing 100081, China 2 National Climate Center, Beijing 100081, China 3.graduate university of Chinese Academy of Sciences, Beijing 100049, China 1. Chinese Academy of Meteorological Sciences Beijing 100081 China 2. National Climate Center Beijing 100081 China 3. graduate university of Chinese Academy of Sciences Beijing 100049 China

Based on the Indian and Chinese precipitation data and the NCEP-NCAR reanalysis circulation data, the relationship between the Indian summer monsoon (ISM) onset and the Meiyu over the Yangtze River Valley has been discussed by the methods of correlation analysis and composite analysis. The results show that the date of ISM onset over Kerala in the southwestern coast of the Indian Peninsula is about two weeks earlier than the beginning of the Meiyu over the Yangtze River Valley. After the outbreak of ISM, the teleconnection mode sets up from the western coast of India via the Bay of Bengal (BOB) to the Yangtze River Valley and southern Japan. It is different both in time and space from the telecon- nection mode which is from the northwest of India via the Tibetan Plateau to northern China. The for- mer mode is defined as the "south" teleconnection of the Asian summer monsoon, forming in the pe- riod of ISM onset; while the latter mode is called the "north" teleconnection, mainly occurring in the Asian monsoon culminant period. During the process of the "south" teleconnection’s formation, the Asian monsoon circulation has experienced a series of important changes: ISM onset, the northward movement of the south Asia high (SAH), the onset vortex occurrence, the eastward extension of the stronger tropical westerly belt, and the northeastward jump of the western Pacific subtropical high (WPSH), etc. Consequently, since ISM sets up over Kerala, the whole Asian continent is covered by the upper SAH after about two weeks, while in the mid- and lower troposphere, a strong wind belt forms from the Arabian Sea via the southern India, BOB and the South China Sea (SCS), then along the western flank of WPSH, to the Yangtze River Valley and southern Japan. With the northward moving of the subtropical jet streams, the upper westerly jet stream and the low level jet have been coupled ver- tically over east Asia, while the Yangtze River Valley happens to locate in the ascending motion

关键词： Indian summer monsoon (ISM) the Meiyu over the Yangtze River Valley teleconnection mode

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Prediction method for October 2003.solar storm

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Science China(Technological Sciences) 2006年第5期49卷 629-640页

作者： XIE Yanqiong1, 2, 3. WEI Fengsi1, FENG Xueshang1 & ZHONG Dingkun1, 2 1. State Key Laboratory of Space Weather, Center for Space Science and Applied Research, Chinese Academy of Sciences, Beijing 100080, China 2. graduate School, Chinese Academy of Sciences, Beijing 10003., China 3. Institute of Meteorology, PLA university of Science and Technology, Nanjing 211101, China State Key Laboratory of Space Weather Center for Space Science Applied Research Chinese Academy of Sciences Beijing 100080 China graduate School Chinese Academy of Sciences Beijing 100039 China Institute of Meteorology PLA University of Science Technology Nanjing 211101 China

Aiming at two intense shock events on October 28 and 29, 2003. this paper presents a two-step method, which combines synoptic analysis of space weather ——“observing” and quantitative prediction ——“palpating”, and then uses it to test predictions. In the first step of “observing”, on the basis of observations of the solar source surface magnetic field, interplanetary scintillation (IPS) and ACE spacecraft, we find that the propagation of the shocks is asymmetric relative to the normal direction of their solar sources, and the Earth is located near the direction of the fastest speed and the greatest energy of the shocks. As the two fast ejection shock events, the fast explosion of coronal mass of the extremely high temperature, the strong magnetic field, and the high speed background solar wind are also helpful to their rapid propagation. In the second step of “palpating”, we adopt a new membership function of the fast shock events for the ISF method. The predicted results show that for the onset time of the geomagnetic disturbance, the relative errors between the observational and the predicted results are 1.8% and 6.7%; and for the magnetic disturbance magnitude, the relative errors are 4.1% and 3.1%, re- spectively. Furthermore, the comparison among the predicted results of our two-step method with those of five other prevailing methods shows that the two-step method is advantageous. The results tell us that understanding the physical features of shock propagation thoroughly is of great importance in improving the prediction precision.

关键词： solar storm, interplanetary shock, interplanetary scintillation, two-step method, ISF method.

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Nitrogen isotopic composition of plant-soil in the Loess Plateau and its responding to environmental change

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Chinese Science Bulletin 2009年第2期54卷 272-279页

作者： LIU WeiGuo1,2 & WANG Zheng1,3.1 State Key Laboratory of Loess and Quaternary Geology, Institute of Earth Environment, Chinese Academy of Sciences, Xi’an 710075, China 2 Xi’an Jiaotong university, School of Human Settlement and Civil Engineering, Xi’an 710049, China 3.graduate university of Chinese Academy of Sciences, Beijing 100049, China Chinese Acad Sci Inst Earth Environm State Key Lab Loess and Quaternary Geol Xian 710075 Peoples R China.

The nitrogen isotope of soil is of emerging significance as an indicator of climatic change and biogeochemical cycle of nitrogen in nature systems. In this paper, the nitrogen content and isotopic composition of modern ecosystems from arid and semiarid Loess Plateau in northwestern China, including plant roots and surface soil, were determined to investigate trends in δ15N variation of plant roots and soil along a precipitation and temperature gradient in northwestern China under the East Asian Monsoon climate condition. The δ15N values of surface soil from the study area vary from ?1.2‰ to 5.8‰, but from -5.1‰ to 1.9‰ in the plant roots. Our results indicate that (1) although the isotopic compositions of both plant roots and surface soil change with a similar trend along the climate gradient, the apparent nitrogen difference between plant roots and soil existed, with -δ15N values ranging from 0.3. to 7.2‰ with average of 4.1‰; and (2) mean annual precipitation (MAP) is the dominant factor for isotopic composition of plant-soil nitrogen in the Loess Plateau, and the δ15N values are less correlated with MAT; we suggest that nitrogen isotopic composition of soil is a potential tracer for environmental changes.

关键词：氮同位素物理性质化学性质环境论

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Power functions with low uniformity on odd characteristic finite fields

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Science China Mathematics 2010年第8期53卷 1931-1940页

作者： ZHA ZhengBang 1,3.& WANG XueLi 2 1 School of Mathematical Sciences,Luoyang Normal university,Luoyang 471022,China 2 School of Mathematical Sciences,South China Normal university,Guangzhou 51063.,China 3.State Key Laboratory of Information Security,graduate university of Chinese Academy of Sciences,Beijing 100049,China 1. School of Mathematical Sciences Luoyang Normal University Luoyang 471022 China3. State Key Laboratory of Information Security Graduate University of Chinese Academy of Sciences Beijing 100049 China2. School of Mathematical Sciences South China Normal University Guangzhou 510631 China

In this paper,we give some new low differential uniformity of some power functions defined on finite fields with odd *** corollaries of the uniformity,we obtain two families of almost perfect nonlinear functions in GF... 详细信息

关键词： almost perfect nonlinear function differential uniform function finite field

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Eclogites in the interior of the Tibetan Plateau and their geodynamic implications

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Chinese Science Bulletin 2009年第15期54卷 2556-2567页

作者： ZHANG KaiJun1,2 & TANG XianChun2,3.1 Department of Earth Sciences, Nanjing university, Nanjing 210093. China 2 Guangzhou Institute of Geochemistry, Chinese Academy of Sciences, Guangzhou 510640, China 3.graduate university of Chinese Academy of Sciences, Beijing 100049, China Department of Earth Sciences Nanjing University Nanjing 210093 China Guangzhou Institute of Geochemistry Chinese Academy of Sciences Guangzhou 510640 China graduate university of Chinese Academy of Sciences Beijing 100049 China

Eclogites have been recently reported in the interior of the Tibetan Plateau, including in the central Qiangtang metamorphic belt, in the Basu metamorphic massif of the eastern Bangong-Nujiang suture zone, and at Songdo and Pengco in the eastern Lhasa terrane. Some typical ultrahigh-pressure (UHP) metamorphic phenomena, e.g., garnet exsolution from clinopyroxene, were documented in the Basu and Pengco eclogites. The UHP metamorphism in the interior of the Tibetan Plateau marked by these eclogites generally took place in the Early Mesozoic. Along with exhumation of these eclogites, (post-) collision-related magmatism extensively occurred around the central Qiangtang belt, the eastern Ban-gong-Nujiang suture zone, and the eastern Lhasa terrane. The occurrence of these Early Mesozoic ec-logites manifests an out-of-sequence evolution of the Tethys, and they could be a product of diachro-nous collision between the eastern Qiangtang terrane and the irregular continental margin of the united western Qiangtang-Lhasa plate, along the linked eastern Bangong-Nujiang-central Qiangtang zone. The collision-related magmatic rocks could have been originated from lithospheric thickening, melting, or detachment due to the collision. The presence of UHP metamorphic rocks in central Qiangtang and Basu implies likely continental deep-subduction, and the denudation of these two metamorphic zones could have served as the source of the Triassic turbidites in the Songpan-Garzê complex and the Ju-rassic turbidites in the western Bangong-Nujiang zone, respectively. However, studies of the eclogites in the interior of the Tibetan Plateau just began, and many principal aspects still remain to be explored, such as their distributions, typical lithologies and minerals, temperature-pressure conditions, timing of formation and exhumation, protoliths and tectonic setting, and relationship with the evolution of the Tethys and large-scale basins in Tibet.

关键词：地球动力学意义青藏高原榴辉岩

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Effect of Crystallinity on Electrochemical Insertion/Extraction of Li in Transition Metal Oxides Part I: LiMn_2O_4 and LiCo_(0.5)Ni_(0.5)O_2

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Journal of Materials Science & Technology 1999年第6期15卷 509-514页

作者： Tomoki TSUMURA and Michio INAGAKI (graduate School of Engineering, Hokkaido university Kita-ku, Sapporo, 060-8628 Japan) Hokkaido Univ Grad Sch Engn Kita Ku Sapporo Hokkaido 0608628 Japan

Electrochemical insertion/extraction of Li on cathode materials of spinel type LiMn2O4 and ordered rock-salt type LiCo0.5 Ni0.5O2 was measured on samples of which structures were well characterized. On the basis of experimental results on structure, morphology and charge-discharge characteristics, the effect of crystallinity of the cathode materiaIs on electrochemical Li insertion/extraction performance was discussed. These two transition metal oxides belong to onegroup that the crystallinity of these oxides affects to the performance.

关键词： LiMn2O4 and LiCo Effect of Crystallinity on Electrochemical Insertion/Extraction of Li in Transition Metal Oxides Part I O2 Ni

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Application of the moist vorticity vector in the analysis of a heavy rainfall event in North China

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Progress in Natural Science:Materials International 2007年第12期17卷 1457-1465页

作者： Zhao Yu1,2,3. Wang Jianguo4 and Xue Deqiang2(1. Laboratory of Cloud-Precipitation Physics and Severe Storms, Institute of Atmospheric Physics, Chinese Academy of Sciences, Beijing 100029, China 2. Shandong Provincial Meteorological Observatory, Jinan 25003., China 3. graduate university of Chinese Academy of Sciences, Beijing 10003., China 4. Shandong Provincial Meteorological Bureau, Jinan 25003., China) Laboratory of Cloud-Precipitation Physics and Severe Storms Institute of Atmospheric Physics Chinese Academy of Sciences Beijing 100029 China Shandong Provincial Meteorological Observatory Jinan 250031 China graduate university of Chinese Academy of Sciences Beijing 100039 China Shandong Provincial Meteorological Bureau Jinan 250031 China

The moist vorticity vector (MVV), defined as (ζa×▽qv)/ρ introduced by Gao et al. is used to study a heavy rainfall event in North China. The MVV has zonal, meridional and vertical components in a three-dimensional framework. Analysis of domain-mean and mass-integrated quantities shows that the variation of the vertical component of the MVV closely follows the variation of the cloud hydrometeors, with a linear correlation coefficient of 0.95, indicating that the vertical component of the MVV is strongly associated with midlatitude convection. Further analysis shows that the vertical component of the MVV reflects the interaction between the horizontal vorticity and the horizontal specific humidity gradient, which can associate dynamic and thermodynamic processes with cloud microphysical processes. Thus, this study can help to understand how the interaction between circulations and clouds aids the development of convection, and the MVV can be used to trace the development and evolution of heavy rainfall.

关键词： moist vorticity vector heavy rainfall modeling study.

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Insulin-sensitizing effects of a novel α-methyl-α-phenoxylpropionate derivative in vitro

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Acta Pharmacologica Sinica 2007年第3期28卷 417-422页

作者： Hao-shu WU~(2,4) Juan-hong YU~(3.4) Ying-yin LI~2 Yu-she YANG~3.Qiao-jun HE~2 Yi-jia LOU~(2,5) Ru-yun JI~3.~2Department of Pharmacology and Toxicology,College of Pharmaceutical Sciences,Zhejiang university,Hangzhou 3.0058,China ~3.tate Key Laboratory of Drug Research,Shanghai Institute of Materia Medica,Shanghai Institutes for Biological Sciences,graduate School of the Chinese Academy of Sciences,Shanghai 201203.China Department of Pharmacology and Toxicology College of Pharmaceutical Sciences Zhejiang University Hangzhou 310058 China Department of State Key Laboratory of Drug Research Shanghai Institute of Materia Medica Shanghai Institutes for Biological Sciences Graduate School of the Chinese Academy of Sciences Shanghai 201203 China

Aim:To examine the insulin sensitizing effects of a novel α-methyl-α-phenoxylpropionate derivative YY20 in insulin-sensitive cell ***:Theperoxisome proliferator-activated receptor γ（PPARγ）agonist bioactivities of YY20were detected by a preadipocyte differentiation ***-PCR and Westernblotting analysis were used to detect the expression of the target gene or *** effects of YY20 on insulin-mediated glucose consumption were determined inthe HepG2 human hepatocellular carcinoma ***:YY20 could enhancethe differentiation of preadipocytes to adipocytes and upregulate the gene ex-pression of PPARγ2,as well as the protein expression of insulin receptor sub-strate-1（IRS-1）,glucose transporter-4（GLUT4）,and adiponectin（ACRP3.）.Theeffects on GLUT4 and ACRP3. could be reversed by the PPARγ inhibitor ***,YY20 efficiently reduced glucose consumptions in HepG2 cells after24 h culture,and the effects were related to insulin and YY20 ***:YY20,a potential insulin-sensitizing agent like rosiglitazone,couldenhance glucose consumption in HepG2 cells in a concentration-and insulin-dependent *** may improve the insulin resistance associated with type 2diabetes.

关键词： YY20 peroxisome proliferator-activated receptor y insulin sensitivity glucose consumption

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