检索结果-南通市图书馆

2010 3rd International Conference on Future BioMedical Information Engineering (FBIE 2010)

作者： Huiyu Xu Department of Immunology University of Qiqihar Medical Qiqihar Heilongjiang Province china Zhiwei Chen Lin Li Hongxin Fei Department of Histology and Embryology University of Qiqihar Medical Qiqihar Heilongjiang Province china

This paper investigate the stable transfection of PDCD5 was observed the change of biological behaviour of tumor and explored the mechanism of augmenting apoptosis-inducing effects of cisplatin on gastric cancer BGC823 *** stable transfection of PDCD5 in all groups cells were examined by realtime PCR and western ***823/PDCD5 cells were assessed the cellular proliferating ability by MTT assay,soft agar cloning experiments and tumorigenicity in nude mice experiments in *** effects of cisplatin in combination with PDCD5 on the proliferation and apoptosis were measured by using MTT analysis,and flow cytometry with Annexin-V-FITC/PI dual labeling and cell cycle,*** was used to detect localization of p53 and PDCD5 combined the therapeutic effect of PDCD5 with cisplatin （5μg/ml for 24 h）.the growth of the 6th and 17th of BGC823/PDCD5 cells was slower than that of BGC823 and BGC823/Neo（p＜0.01）.The stable transfection of PDCD5 appeared G2/M cell cycle arrest,increased apoptosis and led to the nuclear translocation of PDCD5 and p53 treatment with *** stable transfection of PDCD5 gene can inhibit the growth of BGC823 cell line and notably improve apoptosis-inducing effects of cisplatin which is a novel strategy to better chemotherapeutic effects on gastric cancer.

关键词： Programmed Cell Death 5(PDCD5) Cisplatin Apoptosis P53 BGC823

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

Nuclear Stopping as A Probe to In-Medium Nucleon-Nucleon Cross Section in Intermediate Energy Heavy Ion Collisions

Nuclear Stopping as A Probe to In-Medium Nucleon-Nucleon Cro...

引用

CCAST“放射性束物理”研讨会

作者： Jian-Ye Liu, Wen-Jun Quo, Shun-Jin Wang Wei Zuo, Qiang Zhao, Yan-Fang YangCAST (World Laboratory), P. O. Box 8130, beijing 10080. P. R. china center of Theoretical Nuclear Physics, national Laboratory of HeavyIon Accelerator, Lanzhou 730000. P. R. china''hysics, Chinese Academy of JLanzhou 730000, P.R.chinalern Physics. Lanzhou730000. P R. chinaInstitute of Modern Physics, Chinese Academy of Sciences. P. O Box 31Department of Modern Physics. Lanzhou University. Lanziiou

＜正＞Using an isospin-dependent quantum molecular dynamics nuclearstopping in intermediate heavy ion collisions has been studied Thecalculation has been done for colliding systems with different neutron-proton ratios in beam energy ranging from 15MeV/u to 150MeV/u It isfound *** the energy region from above Fermi energy to 150MeV/unuclear stopping is very sensitive to the isospin dependence of in-mediumnucleon-nucleon cross section,but insensitive to symmetry *** this investigation,we propose that nuclear stopping can be usedas a new probe to extract the information on the isospin dependence ofin-medium nucleon-nucleon cross section in intermediate energy heavyion collisions.

关键词：

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

Simultaneous Localization and Map Building Using Constrained State Estimate Algorithm

Simultaneous Localization and Map Building Using Constrained...

引用

第二十七届中国控制会议

作者： Cao Menglong1,2,Yu Lei1,Cui Pingyuan2 1.Institute of Autonomous Navigation and Intelligent Control,Qingdao University of Science & Technology,Qingdao 266042,P.R.china 2.Deep Space Exploration Research center,Harbin Institute of Technology,Harbin 150001,P.R.china

Intelligent vehicles and autonomous robots are viable in complex environments,the reliable and robust localization function of which is *** to the large variability and uncertainty of complex environments,it is difficult to rely on a specific method or a set of sensor data to correctly and robustly estimate the robot *** key to solving the localization problem is to optimally use and fuse all useful sources of information available to the mobile *** is common to have approximate digital maps of the road network.A framework for simultaneous localization and map building（SLAM） problems using road constrained Kalman filter algorithms is developed,with the emphasis on vehicle applications in large *** presents the problems of outdoor navigation in areas with combination of features and onroad *** aided SLAM algorithms,which incorporate absolute information in a consistent manner,are *** filters are commonly used to estimate the states of a mobile ***,in the application of Kalman filters,the known model or signal information often are either ignored or dealt with *** instance,constraints on state values which may be based on physical considerations are often neglected because they do not fit easily into the structure of the Kalman *** paper develops a rigorous analytic method of incorporating state equality constraints in the Kalman *** constraints may be time-varying,but it significantly improves the prediction accuracy of the *** SLAM implementation uses the road constrained kalman filter algorithm to maintain the error of vehi-cle’s location and ***,the use of this algorithm is demonstrated on a simple vehicle tracking problem.

关键词： SLAM Outdoors navigation Guidance Mobile vehicles State Constraints Estimation

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

激光增材制造Ti60A钛合金的氧化行为

引用

中国激光 2018年第7期45卷 94-101页

作者：刘金王薇茜程序汤海波北京航空航天大学大型金属构件增材制造国家工程实验室北京100191 北京航空航天大学材料科学与工程学院北京100191 国防科技工业激光增材制造技术研究应用中心北京100191 大型整体金属构件激光直接制造教育部工程研究中心北京100191 大型关键金属构件激光直接制造北京市工程技术研究中心北京100191

利用激光增材制造技术制备了沉积态和锻态Ti60A钛合金,并在600~800℃温度下进行了氧化实验,研究了不同氧化条件下试样的增重量及显微硬度的变化规律。结果表明,沉积态和锻态Ti60A合金的表面氧化产物主要由Ti O2和Al2O3构成,氧化层的生... 详细信息

利用激光增材制造技术制备了沉积态和锻态Ti60A钛合金,并在600~800℃温度下进行了氧化实验,研究了不同氧化条件下试样的增重量及显微硬度的变化规律。结果表明,沉积态和锻态Ti60A合金的表面氧化产物主要由Ti O2和Al2O3构成,氧化层的生成是由氧向基体内扩散与Al和Ti元素向外扩散的共同作用所致;在相同的实验条件下,与锻态的相比,沉积态Ti60A合金氧化增重量更小,表面氧化层更致密,厚度更小,氧元素的扩散深度更小,高温抗氧化性能更好。

关键词：激光技术激光增材制造氧化温度氧化性能 Ti60A

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Activation of caspase by temozolomide contributes to apoptosis in gonadotroph adenoma cells via bcl-2 inhibitionandparpcleavage

Activation of caspase by temozolomide contributes to apoptos...

引用

2011医学科学前沿论坛第十二届全国肿瘤药理与化疗学术会议

作者： Sihai MA~a,M.D.,Ph.D.,Xiaohai Liu~a,M.D.,Ph.D.,Yong Yao~a,M.D.,FengCai~a,M.D.,Ph.D.,Congxin Daia,M.D.,Ph.D., XinjieBao~a M.D.,Ming Feng~a M.D.,Junji Wei~a M.D.,Guilin Li~a M.D,Wenbin Ma~a,M.D,Bo Zhang~b,M.D.,Li Shen~c,Ph.D., LingsongLi~c,M.D.,Ph.D.,RenzhiWang~(a,*),M.D. a Department of Neurosurgery,Peking Union Medical College Hospital,ChineseAcademy of Medical Sciences and Peking Union Medical College,beijing 100730.P.R.china b Department of Neurosurgery,the First Affiliated Hospital of Dalian Medical University,Dalian 116011,PR.china c Peking University Stem Cell Research center and national center for International Research,Peking University,beijing,P.R. china.

*** NFPAs frequently require multimodality treatment including microsurgery,radiation therapy and radiosurgery,but lack of available pituitary-suppressive *** effectiveness and mechanism of temozolomide(TMZ) in terms of growth suppression on NFPAs is evaluated. *** adenoma cell lines-αT3-1-were used.A dose escalation of TMZ was performed forαT3-1

关键词：

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

Sildenafil attenuates LPS-induced pro-inflammatory responses through down-regulation ROS-related MAPK/NF-kappaB as well as cGMP related signaling pathways in N9 microglia

Sildenafil attenuates LPS-induced pro-inflammatory responses...

引用

第五届中日基础和临床药理学双边学术会议

作者： Jingyu Yang~1,Siqi Zhao~1,Lijia Zhang~1,Guoning Lian~1,Xiaoxiao Wang~1,Haotian Zhang~1,Xuechun Yao~1,Jiming Wang~2,Chunfu Wu~(1*) 1 Department of Pharmacology,Shenyang Pharmaceutical University,Shenyang,china 2 Laboratory of Molecular Immunoregulation,Cancer and Inflammation Program, center for Cancer Research,national Cancer Institute at Frederick,Frederick,MD,USA

＜正＞Excessive activation of microglial cells has been implicated in various *** present study showed that sildenafil,a PDE5 inhibitor,significantly suppressed NO production through decreasing the protein and/or mRNA expressions of inducible NO synthase（iNOS）,as well as decreased the mRNA expressions and release of interleukin 1β（IL-1β） and tumor necrosis factorα（TNF-α）.induced by LPS in microglial

关键词：

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

怀来盆地不同土地利用方式对土壤质量的影响分析

引用

水土保持学报 2004年第6期18卷 103-107页

作者：李新宇唐海萍赵云龙张新时北京师范大学资源学院环境演变与自然灾害教育部重点实验室北京100875 国家农业信息化工程技术研究中心北京100089

基于对河北省怀来县官厅水库南北两岸8种主要土地利用类型的土壤养分、pH值和土壤容重等的分析,讨论了不同土地利用方式对土壤质量的影响,并评价了不同土地利用方式下的土壤退化程度。结果表明:怀来县官厅水库北岸的防护林地,由于合理... 详细信息

基于对河北省怀来县官厅水库南北两岸8种主要土地利用类型的土壤养分、pH值和土壤容重等的分析,讨论了不同土地利用方式对土壤质量的影响,并评价了不同土地利用方式下的土壤退化程度。结果表明:怀来县官厅水库北岸的防护林地,由于合理的土地利用管理与保护措施,土壤容重最低,土壤养分含量高于其它几种土地利用方式;而由坡耕地撂荒后演替而来的草地,由于当地干旱寒冷多风的气候环境,土壤的母质条件以及缺乏有效的恢复措施等原因引起土壤质量继续退化;在长期不合理的土地管理措施影响下位于水库南岸的防护林地及葡萄园、果园、玉米地等土壤也发生较严重退化,表现为土壤容重、pH值显著增加,大部分土壤养分显著降低。土壤退化指数的计算结果也表明草地及南岸的玉米地、葡萄园的土壤发生了较严重的退化。在对数据进行处理分析过程中发现,土壤有机质、有机碳与全氮之间存在显著正相关关系。

关键词：怀来盆地土地利用方式土壤质量影响分析

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Biochemical and cellular and control of S-RNase-based self-incompatibility in flowering plants

Biochemical and cellular and control of S-RNase-based self-i...

引用

从植物科学到农业发展——2012全国植物生物学大会

作者： Jiangbo Fan,Wei Liu,Qun Li,Yu’e Zhang,Yongbiao Xue~* State Key Laboratory of Molecular Developmental Biology,Institute of Genetics and Developmental Biology,Chinese Academy of Sciences and national center for Plant Gene Research,beijing 100101.

Self-incompatibility(SI) is an intra-specific reproductive barrier to prevent self-fertilization and to promote cross-fertilization found in flowering *** the SI response,self or genetically related pollen is rejected by the pistil and non-self(cross) pollen accepted for *** outcomes are referred to as self-pollen incompatibility(SPI) and cross-pollen compatibility(CPC),*** studies show that a single polymorphic S-locus,encoding at least two components from both the pollen and pistil sides,controls the discrimination of self and cross *** studies have revealed that plants use several distinct molecular mechanisms to accomplish the SI *** them,the Solanaceae,Plantaginaceae and Rosaceae appear to share a similar molecular *** these families,the SI specificity is determined by a ribonuclease protein (S-RNase) expressed in the pistil and a cluster of S-Locus F-box protein(SLF/SFB) in *** is widely accepted that S-RNases are secreted by the pistil and taken up by growing pollen tubes and function as cytotoxins to arrest self-pollen tube ***, the biochemical and cellular mechanisms remain largely *** this talk,I will present our recent data showing where and how S-RNase and SLF interact with each other to control CPC and SPI responses in Petunia hybrid,a solanaceous species.

关键词： self-incompatibility S-RNase SLF Petunia hybrida

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

Robust H∞ Filter Design for 2DFM Model

Robust H∞ Filter Design for 2DFM Model

引用

第二十六届中国控制会议

作者： Meng Xiangyu1,Gao Huijun1,Chen Tongwen2 1.Space Control and Inertial Technology Research center,Harbin Institute of Technology,Harbin 150001,P.R.china2.Department of Electrical and Computer Engineering,University of Alberta,Edmonton,Alberta T6G 2V4,Canada

This paper is concerned with the robust H∞ filtering problem for uncertain two-dimensional（2-D）systems described by the Fornasini-Marchesini *** polynomially parameter-dependent idea is first utilized to solve the robust H∞ filtering problem,with sufficient conditions for existence of the desired H∞ filters expressed in terms of linear matrix inequalities（LMIs）.These conditions are developed based on homogeneous polynomially parameter-dependent matrices of arbitrary *** the degree grows,test of increasing precision is obtained providing less conservative filter *** example is given to show the effectiveness of the proposed approach.

关键词： 2D systems H∞ filtering Linear matrix inequality Robust filtering

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

Behaviors of Cementites in Medium Carbon Low Alloy Steels during Surface Nanocrystallization

Behaviors of Cementites in Medium Carbon Low Alloy Steels du...

引用

第五届国际低合金高强度钢会议暨第三届国际超细晶粒钢会议

作者： ZHANG Junbao1 LIU Yuliang2 SONG Hongwei1 WU Jie2 SHI Bi1 XIONG Tianying2 (1. Baosteel Technology center Baoshan Iron & Steel CO. LTD. Shanghai 201900 china 2. Institute of Metal Research Chinese Academy of Sciences Shenyang 110016 china)

Behaviors of cementites in surface nanocrystallized layers of medium carbon low alloy steel induced by different methods were systematically investigated using XRD analysis, TEM and M?ssbauer spectra.

关键词： surface nanocrystallization cementite medium carbon low alloy steel dissolution.

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：