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Game Analysis for the Pricing Strategy in Manufacturer-Retailer Supply Chains

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厦门大学学报（自然科学版） 2002年第S1期41卷 271-272页

作者： MOU De-yi (college of IT, Nankai Univ., tianjin 300071, china college of Math, CAUC tianjin 300300, china)

Supply Chain Management(SCM) is the term used to de sc ribe the management of the flow of materials, information and funds across the e ntire supply chain, from suppliers to component producers to final assemblers to distribution(warehouses and retailers) and ultimately to the *** pap er studies the coordinated problem for a manufacturing and retailing supply chai n. Differentiating from traditional joint optimization in the literature, the ap proach applies game theory structure as the researching framework to address the problem of coordinating the pricing decisions of the manufacturer and retailer. Three co-op pricing models are developed and discussed which are based on two noncooperative games and one cooperative game. They are a Stakelberg’s two-sta ge game model, a simultaneously move game model and an cooperative game model, r espectively. The results obtained by the sufficient comparisons and discusses te ll us that the noncooperative equilibriums are lower efficiently than joint coop erative equilibrium. In order to get the efficient cooperative mechanism, we int roduce the Pareto efficiency concept and obtain so-called feasible Pareto effic ient set of pricing schemes (contract curve). The cooperative mechanism based on the curve would be solid and stable. These and orther related managerial issues are explored in this paper.

关键词： decision analysis game theory co-op pricing e quilibrium coordination efficiency

宁泌泰胶囊在良性前列腺增生中临床应用中国专家共识

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中草药 2024年第5期55卷 1436-1442页

作者：宁泌泰胶囊临床应用中国专家共识编写组中国中医药信息学会男科分会俞旭君李俊君郭军不详成都中医药大学附属医院成都市第五人民医院中国中医科学院西苑医院

良性前列腺增生(benign prostatic hyperplasia,BPH)是以下尿路症状(lower urinary tract symptoms,LUTS)为特征的中老年男性常见慢性疾病,严重影响患者生活质量。BPH现有的各种治疗手段仍存在一定的局限性,积极探索新的有效治疗措施提... 详细信息

良性前列腺增生(benign prostatic hyperplasia,BPH)是以下尿路症状(lower urinary tract symptoms,LUTS)为特征的中老年男性常见慢性疾病,严重影响患者生活质量。BPH现有的各种治疗手段仍存在一定的局限性,积极探索新的有效治疗措施提高疗效是亟待解决的问题。宁泌泰胶囊来源于苗族经典验方,具有清热解毒、利湿通淋的功效,可针对湿热蕴结证BPH引起的LUTS发挥治疗作用。多个指南及专家共识均已提出将宁泌泰胶囊作为改善BPH临床症状的主要用药。因此,本专家共识旨在指导临床医师合理、规范的使用宁泌泰胶囊,充分发挥中医药在BPH治疗中的应用优势。

关键词：良性前列腺增生下尿路症状宁泌泰胶囊专家共识慢性前列腺炎尿路感染

APPLICATION OF REMOTE SENSING TECHNOLOGY TO POPULATION ESTIMATION

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chinese Geographical Science 2003年第3期13卷 267-271页

作者： ZHANG Bao-guang(college of Urban and Environmental Science, tianjin Normal University, tianjin 300074, P. R. china) college of Urban and Environmental Science Tianjin Normal University Tianjin P. R. China

This paper attempts to explore a new avenue of urban small-regional population estimation by remote sensing technology, creatively and comprehensively for the first time using a residence count method, area (density) method and model method, incorporating the application experience of American scholars in the light of the state of our country. Firstly, the author proposes theoretical basis for population estimation by remote sensing, on the basis of analysing and evaluating the history and state quo of application of methods of population estimation by remote sensing. Secondly, two original types of mathematical models of population estimation are developed on the basis of remote sensing data, taking tianjin City as an example. By both of the mathematical models the regional population may be estimated from remote sensing variable values with high accuracy. The number of the independent variables in the latter model is somewhat smaller and the collection of remote sensing data is somewhat easier, but the deviation is a little larger. Finally, some viewpoints on the principled problems about the practical application of remote sensing to population estimation are put forward.

关键词： remote sensing technology population estimation mathematical model

Meet Our New Editorial Board Members of Spotlights

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chinese Journal of Chemistry 2024年第16期42卷 1932-1936页

作者： Editorial Office of chinese Journal of Chemistry 不详

Editorial Board Member of *** ***,college of Materials Science and Engineering Beijing University of Chemical ***:2006-2010,B.S.,Materials Science and Engineering,Beijing University of Chemical Technology.2010-2015,Ph... 详细信息

关键词： Spotlight Editorial Board

Overexpression of Aurora-A kinase promotes tumor cell proliferation and inhibits apoptosis in esophageal squamous cell carcinoma cell line

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Cell Research 2006年第4期16卷 356-366页

作者： Xiao Xia Wang~(1,2) Rong Liu~1 Shun Qian Jin~1 Fei Yue Fan~2 Qi Min Zhan~1 ~1State Key Laboratory of Molecular Oncology,Cancer Institute,chinese Academy of Medical Sciences and Peking Union Medical college,Beijing 100021,china ~2Institute of Radiation medicine,chinese Academy of Medical Sciences and Peking Union Medical college,tianjin 300192,china State Key Laboratory of Molecular Oncology Cancer Institute Chinese Academy of Medical Sciences and Peking Union Medical College Beijing China Institute of Radiation medicine Chinese Academy of Medical Sciences and Peking Union Medical College Tianjin China

Aurora-A kinase,a serine/threonine protein kinase,is a potential *** and overexpression of Au-rora-A have been found in several types of human tumors,including esophageal squamous cell carcinoma(ESCC).It hasbeen demonstrated that cells overexpressing Aurora-A are more resistant to cisplatin-induced ***,themolecular mechanisms mediating these effects remain largely *** this report,we showed that overexpressionof Aurora-A through stable transfection of pEGFP-Aurora-A in human ESCC KYSE150 cells significantly promotedcell proliferation and inhibited cisplatin- or UV irradiation-induced *** of caspase-3 and poly(ADP-ribose)polymerase(PARP)in Aurora-A overexpressing cells were substantially reduced after cisplatin or UV ***,we found that silencing of endogenous Aurora-A kinase with siRNA substantially enhanced sensitivityto cisplatin- or UV-induced apoptosis in human ESCC EC9706 *** parallel,overexpression of Aurora-A potentlyupregulated the expression of ***,the knockdown of Bc1-2 by siRNA abrogated the Aurora-A's effect oninhibiting *** together,these data provide evidence that Aurora-A overexpression promoting cell proliferationand inhibiting apoptosis,suggesting a novel mechanism that is closely related to malignant phenotype and anti-cancerdrugs resistance of ESCC cells.

关键词： Aurora-A apoptosis caspase-3 PARP esophageal squamous cell carcinoma (ESCC) siRNA

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女性压力性尿失禁中医诊疗指南(2023)

中医杂志 2024年第13期65卷 1408-1416页

作者：中华中医药学会女性压力性尿失禁中医诊疗指南项目组周艳艳丁家森高瞻邵魁卿不详中国中医科学院西苑医院

压力性尿失禁(stress urinary incontinence,SUI)是指喷嚏、咳嗽、大笑、运动等腹压增加时,尿液不自主地从尿道外口漏出,是影响女性生活质量的常见疾病,病因主要为年老体弱、妊娠分娩损伤、肥胖等[1]。随着人口老龄化、生活方式及饮食... 详细信息

压力性尿失禁(stress urinary incontinence,SUI)是指喷嚏、咳嗽、大笑、运动等腹压增加时,尿液不自主地从尿道外口漏出,是影响女性生活质量的常见疾病,病因主要为年老体弱、妊娠分娩损伤、肥胖等[1]。随着人口老龄化、生活方式及饮食结构的改变,女性SUI患者数量逐渐增加[2],尿失禁带来的生理及心理问题逐渐受到社会重视。2006年,由北京协和医院牵头的全国大范围横断面研究结果显示,中国成年女性SUI的患病率为18.9%[3];2019年发表的一项Meta分析结果显示,SUI的患病率为18.8%[4].

关键词：压力性尿失禁性生活质量尿道外口横断面研究妊娠分娩 Meta分析饮食结构患病率

Regulative Function of Low Molecular Chitosan on Blood Sugar in Experimental Diabetic Rats

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生物医学工程学杂志 2005年第S1期22卷 167-168页

作者： Hua-Bing YANG Yong WU (Department of Preclinical medicine, Hubei college of traditional chinese medicine, Wuhan 430061,china) Department of Preclinical medicine Hubei College of Traditional Chinese Medicine Wuhan 430061 China

1 IntroductionChitosan has good action on reducing blood sugar with low poisonous side-effect. Low molecular chitosan(LMC) is the oxide of high molecular chitosan, which has water-solubility and the function of lowering blood sugar of diabetic rats. In this experiment, STZ was adopted to duplicate the model rats of Type Ⅱ diabetes mellitus, the regulative function of LMC on Type Ⅱ diabetic blood sugar was observed for further inquiry into its functionary mechanism.

关键词： STZ Regulative Function of Low Molecular Chitosan on Blood Sugar in Experimental Diabetic Rats

Tetramethylpyrazine protected photoreceptor cells of rats by modulating nuclear translocation of NF-κB

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Acta Pharmacologica Sinica 2005年第7期26卷 887-892页

作者： Jin-nan YANG~(2,3) Jin-mao CHEN~4 Lin LUO~4 Shao-chun LIN~4 Dai LI~4 Shi-xing HU~(4,5,6) 2 School of Pharmacy,Xinxiang Medical college,Xinxiang 453003,china 4 Zhongshan Ophthalmic Centre,Sun Yat-sen University,Guangzhou 510060,china 5 Eye Hospital of china,Academy of traditional chinese medicine,Beijing 100040,china School of Pharmacy Xinxiang Medical College Xinxiang China Zhongshan Ophthalmic Centre Sun Yat-sen University Guangzhou China Eye Hospital of china Academy of Traditional Chinese Medicine Beijing China

Aim:To evaluate the effect of tetramethylpyrazine(TMP)injection on retinaldamage induced by N-methyl-N-nitrosourea(MNU)in rats and on nuclear factor-kappa B(NF-κB)family ***:Female Sprague-Dawley(SD)ratswere randomly divided into groups:(i),control group;(ii),model group;and(iii),TMP-injection groups,in which the rats were subdivided into 40 mg/kg,80 mg/kgand 160 mg/kg *** were injected ip into 47-day-old SD rats once a *** 50 days of age,all rats in the model group and drug groups also received asingle ip injection of 60 mg/kg *** in group 1 received ip injection ofphysiological *** rats were killed at different times after MNU or physi-ological saline *** apoptotic index of photoreceptor cells was calcu-lated by TUNEL labeling;retinal damage was evaluated based on retinal thicknessand the expression of NF-κB family members was detected by Western ***:TMP injections,in a dose-dependent manner,suppressed photorecep-tor cell apoptosis and decreased its loss in the peripheral *** comparedwith the MNU-treated group,TMP injection at a dose of 160 mg/kg also time-dependently upregulated the NF-κB/p65 protein level in the nucleus anddownregulated the IκBα protein level in the ***,no protectiveeffect of TMP injection on MNU-induced central retinal damage was ***:TMP injection partially protects against MNU-induced retinal dam-age by upregulating the nuclear translocation of p65 to inhibit photoreceptor cellsapoptosis.

关键词： tetramethylpyrazine photoreceptors methylnitrosourea apoptosis NF-kappa B retinitis pigmentosa

猴头健胃灵片治疗慢性胃炎、消化性溃疡临床应用专家共识

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中国实验方剂学杂志 2024年第20期30卷 96-102页

作者：中华中医药学会杨洋邹多武魏玮不详中国中医科学院望京医院上海交通大学附属瑞金医院(西医组) 中国中医科学院望京医院(中医组)

慢性胃炎、消化性溃疡是常见的上消化道疾病,临床均以胃脘疼痛或胃脘胀满为主要临床表现。猴头健胃灵片是临床广泛应用的治疗胃脘疼痛或胃脘胀满的中成药,治疗慢性胃炎、胃及十二指肠溃疡临床使用安全,疗效显著。该共识经中华中医药学... 详细信息

慢性胃炎、消化性溃疡是常见的上消化道疾病,临床均以胃脘疼痛或胃脘胀满为主要临床表现。猴头健胃灵片是临床广泛应用的治疗胃脘疼痛或胃脘胀满的中成药,治疗慢性胃炎、胃及十二指肠溃疡临床使用安全,疗效显著。该共识经中华中医药学会立项及审核公布,编制遵循“科学性、清晰性、逻辑一致性”原则,按照中华中医药学会中成药临床应用专家共识制定的技术方案开展工作,采用“文献研究”“专家访谈”“临床问卷调查法”“名义组法”等相结合的研究方法,经国内50余名中、西医临床与方法学、药学等多学科专家共同研制。该共识旨在明确猴头健胃灵片治疗慢性胃炎、消化性溃疡临床疗效,完善其适应证,补充其安全性问题。该共识针对临床一线调查总结的临床问题,对有证据支持的临床问题,通过建议评估制定评价证据分级系统(GRADE)进行循证评价形成推荐意见;对证据支持不充分临床问题,通过名义组法达成专家共识,形成“共识建议”。该共识对猴头健胃灵片适应证及临床疗效、用法用量、疗程等进行了推荐或建议,并完善了安全性信息。共识稿件在全国范围内进行征求意见和同行评议,完成质量评价、适用性评价及目标用户评价。该共识为猴头健胃灵片临床的合理用药提供参考。

关键词：猴头健胃灵片慢性胃炎消化性溃疡萎缩性胃炎专家共识