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Fatal attraction:A novel mechanism of bacterial pathogenesis against nematodes

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Fatal attraction:A novel mechanism of bacterial pathogenesis...

A Thermochemical Study of the Reaction of Lanthanum Nitrate with Alanine

2008年中国微生物学会学术年会

作者： Xiaowei Huang~(1+),Qiuhong Niu~(1+),Lin Zhang~1,Jianping Xu~2,Dongmei Yang~1,Kangbi Wei~1,Xuemei Niu~1,Lei Wang~3.Chenggang Zou~1,Jinkui Yang~1 and Ke-qin Zhang~(1*) 1 Laboratory for Conservation and Utilization of Bio-Resources,and Key Laboratory for Microbial Resources of the Ministry of Education,Yunnan university,Kunming,Yunnan,650091,PR China 2 department of Biology,McMaster university,1280 Main St.West,Hamilton,Ontario,L8S {3.1,Canada 3.Research Center for Functional Genomics and Biochip Technology,TEDA School of Biological Sciences and Biotechnology,Nankai university,Tianjin,3.0{3.7,PR China

Nowadays the growing world food crisis is threatening people and the WTO has estimated that the crisis may leave an additional 100 million people hungry by the end of ***,plant parasite nematodes are among the most important agricultural pests,and it was estimated that the crop losses caused by plant parasite nematodes were 12.3.per year ***,nematode management

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Chemical Research in Chinese Universities 2000年第4期16卷 347-350页

作者： LI Qiang-guo (department of Chemistry, Chenzhou Teacher’ s College, Hunan 4.3.00, P. R. China) 郴州师范高等专科学校湖南郴州 423000

The standard molar reaction enthalpy of the solid-solid coordination reaction La(NO3.3. 6H2O (s) +4.la(s) (Ala is Alanine)=La(NO3.3.(Ala)4.H2O(s) + 5H2O(1) was studied by using classical solution calorimetry. The molar dissolution enthalpies of the reactants and the product of the solid-solid coordination reaction in 2 mol/L HCl were measured by using an isoperibol calorimeter. From the results and other auxiliary quantities, the standard molar formation enthalpy of [La (NO3.3.(Ala)4.H2O, s, 298. 15 K] has been determined to be △fHm[La(NO3.3.(Ala)4.H2O, s, 298. 15 K]=-3.864. 24. kJ/mol.

关键词： Lanthanum nitrate Alanine Thermochemistry Standard molar formation enthalpy

Enzyme-Linked Immunoelectrotransfer Blot Assay(EITB)For Detecting IgG and IgG4.Antibody in Serum of Human Neurocysticercosis

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Enzyme-Linked Immunoelectrotransfer Blot Assay(EITB)For Dete...

江苏弶港附近强潮环境有孔虫埋葬群特征及其地质意义

中国动物学会第六届全国青年寄生虫学工作者学术讨论会

作者： Wu Jing Li Yajie Liu Ping Wang Hui department of Parasitology, Harbin Medical university Harbin, 150086

Total 　IgG and IgG subclass antibody were investigated in serum ofneurocysticercosis patients who were divided into four *** first group consisted ofparasitological and clinically confirmed patients before *** second,third andfourth groups comprised treated patients after 1-3.4.6 and 7-9 therapeutic coursesrespectively(Each therapeutic course include 10-14.dnys).24. serum samples from thesefour groups were detected with EITB using lentil-lectin affinity purified antigens for totalIgG and IgG.3. sera from healthy individuals were used as negative *** alsodetected 27 sera from patients of echinococcosis and clonorchiosis by the same *** to negative Control the total IgG and IgG Subclass antibody levels in fourdifferent groups were respectively 96.3. and 97.5% for the lst group;93.3. and 78.6%for the 2ed;88.0% and 3..0% for the 3.d;86.1% and 13.9% for the *** was nosignificant difference for the total IgG among these four groups(p>0.01),In *** of IgG antibodies in the post-treatment patients were lower than that of the before-treatmet *** positive rate of IgG antibody in symptomatic post-treatmentpatients is 77.0% but in asymptomatic post-treatment patients is only 21.3.(P4. and GP24.ere the most common bands recognized by many patients for IgG,but in the latter twogroups,IgG distinctively recognized low molecular weight antigen of 18kD and 13.D3. sera ftom healthy individuals were all *** positive rate of total lgG antibodyin 27 Sera from heterologous infections is 7.5% in contrast ,IgG antibody of these serawere all *** observation confirmed that IgG is an important diagnosticparameter for cure of human neurocysticercosis.

关键词： neurocysticercosis total IgG IgG4.subclass EITB.

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微体古生物学报 1993年第2期10卷 113-129页

作者：何浩明南京大学大地海洋科学系南京210008

江苏弶港附近若干近岸强潮环境,包括海滨沼泽、潮间带浅滩及潮流沙脊,其表层沉积物中的有孔虫埋葬群由4.属98种组成,本区可划分出两个组合区,三个亚区。各亚区的平均复合分异度H(S)值变化于2.4.2.99之间,均远远高于黄、东海沿岸一般的... 详细信息

江苏弶港附近若干近岸强潮环境,包括海滨沼泽、潮间带浅滩及潮流沙脊,其表层沉积物中的有孔虫埋葬群由4.属98种组成,本区可划分出两个组合区,三个亚区。各亚区的平均复合分异度H(S)值变化于2.4.2.99之间,均远远高于黄、东海沿岸一般的海滨沼泽及潮间带浅滩。在所有取样点中,H(S)值最高为3.3.,该点(53.0})竟位于距陆地最近、滩面最高的海滨沼泽上;而H(S)值最低为1.68。该点(23.站)却位于潮间下带的外缘。本区某些H(S)高值的异常分布及逆向梯度分布,可与环境的盐度、深度、温度因子无关,而与强潮、风暴潮以及不同方向的潮流汇合带等特殊动力因子有关。本区N(50克干样)等值线图表明,在淤蚀多变的强潮环境里,N值主要不是与沉积速率有关,而是与沉积体的年龄有关。弶港附近湖滩有孔虫埋葬群的特殊组合及其特征参数分布模式,为在地层中辨认这类近岸强潮环境提供了参考标志。

关键词：有孔虫强潮环境埋葬群江苏

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甲壳动物的环境型性决定和性比研究

台湾海峡 1990年第3期9卷 191-199页

作者：郑重厦门大学海洋系 361005

本文评述了甲壳动物的性决定和性比与环境关系问题的研究结果,论述了枝角类、端足类和其他甲壳动物的性决定的内、外因子,评价了Berg的“压抑”假说,并对今后该方面的研究重点,提出了意见和建议。

关键词：甲壳动物环境型性性别比例决定

Gene heterogeneity of hepatitis B virus isolates from patients with severe hepatitis B

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Hepatobiliary & Pancreatic Diseases International 2005年第4期4卷 530-534页

作者： Wei Wu, Yu Chen, Bing Ruan and Lan-Juan Li Hangzhou, China department of Infectious Diseases, First Affiliated Hospital, Zhejiang university School of Medicine, Key Laboratory of Infectious Diseases of Health Ministry of China, Hangzhou 3.0003. China department of Infectious Diseases First Affiliated Hospital Zhejiang University School of Medicine Key Laboratory of Infectious Diseases of Health Ministry of China Hangzhou 310003 China.

BACKGROUND: The pathogenesis of severe hepatitis B remains unknown. Reports have indicated that hepatitis B virus (HBV) mutations are important factors in the pathogenesis of this disease. This study was to investigate the genetic heterogeneity of HBV strains from serum samples of patients with fulminant hepatitis B. METHODS: Full-length HBV genomes from 4.patients with severe hepatitis B were cloned and sequenced to observe mutations in every open reading-frame ( ORF). Serum samples of another 25 patients with severe hepatitis B, 3. patients with chronic hepatitis B, and 25 HBV carriers were collected for sequencing and comparison of mutations in preS2, preC and core promoter regions. RESULTS: Of 4.HBV full-length genome sequences, 3.had a G to A mutation at nucleotide A1896 in the preC region and 1 had double mutations of T1762-A1764.in the core promoter region. The 4.sequences showed mutations in the known B or T cell epitopes of the preS2 and C regions. For the other 3.groups, more mutations were seen in the preS2 region in the HBV isolates from the patients with severe hepatitis B than those from the patients with chronic hepatitis B and HBV carriers (P 3.and C1753.were 4..0% and 24.0% respectively in the patients with severe hepatitis B, but none of these mutations were observed in the patients with chronic hepatitis B group or HBV carriers (P 4.was 76.0% in the patients with severe hepatitis B, 4..0% in the patients with chronic hepatitis B (P <0. 01) , and 16. 0% in the HBV carriers ( P < 0. 01). There was a significant difference in A1896 mutation between the patients with severe hepatitis B and the patients with chronic hepatitis B (P < 0. 05 ) o

关键词： hepatitis B virus severe hepatitis virus genome gene heterogeneity preS2 preC core promoter

Relationship between Aberrant Methylation of FAS Promoter and Biological Behavior of Bladder Urothelial Carcinoma

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Journal of Huazhong university of Science and Technology(Medical Sciences) 2011年第6期31卷 794-798页

作者：李伟夏丁王元宝李翌薛艳丽吴辛叶章群 department of Urology Tongji Hospital Tongji Medical College Huazhong University of Science and Technology department of Urology the People's Hospital of Yunnan Province

This study examined the promoter methylation of APO-1/CD95 （Fas） gene in bladder urothelial carcinoma and analyzed the relationship between the Fas promoter methylation and the biological behavior of bladder cancer. Promoter methylation of Fas gene was detected by methylation-specific PCR （MSP） in 4.bladder cancer cell lines, 50 human bladder urothelial carcinoma samples and 10 normal bladder tissue samples. Correlation of the aberrant methylation of Fas promoter with the clinicopathological parameters was statistically analyzed. The results showed that Fas was down-regu- lated at both mRNA and protein level in bladder cancer cell lines and tissue samples of bladder urothelial carcinoma. The positive rate of Fas protein expression in bladder urothelial carcinoma was 3.0}0% （17/50）, significantly lower than that in normal bladder tissues （70.0%, 7/10）（P〈0.01）. Fas promoter methylation was detected, and the positive rate of Fas promoter methylation in bladder urothelial carcinoma was 4..0% （21/50）, which was obviously higher than that in normal bladder tissues （0.0%, 0/10）（P〈0.01）. The aberrant methylation of Fas promoter was reversely correlated with Fas protein expression （P〈0.05）. Furthermore, the positive rates of Fas promoter methylation in high-grade and low-grade bladder urothelial carcinoma were 73.3. （11/15） and 3.0}2% （12/3.）, respectively, with significant difference shown （P〈0.05）. No statistical significance was found in the Fas promoter methylation among different clinical stages of bladder cancer. It was concluded that Fas promoter hypermethylation plays an important role in the pathogenesis of bladder urothelial carcinoma and may serve as a prognostic indicator of bladder urothelial carcinoma.

关键词： bladder carcinoma Fas methylation

UNLEASH ANTIGEN-SPECIFIC ANTI-TUMOR IMMUNITY

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UNLEASH ANTIGEN-SPECIFIC ANTI-TUMOR IMMUNITY

Preparation and Microstructure of Spinel Zinc Ferrite ZnFe_2O_4.by Co-precipitation Method

第11次中国实验血液学会议

作者： department of Pharmacology,Temple university School of Medicine,Philadelphia,PA 1914.,U.S.A.Xiao-Feng Yang

＜正＞Significant progresses have led to the renais- sance of tumor immunology and studies on anti- tumor ***,despite of the pro- gress in the field of tumor immunology and immuno- therapy,current antigen-specific immunotherapies for tumors are far less satisfied than expected,which reflects the need to continuously improve our under- standing on tumor immunology and immunobiology per *** this brief review,we outline the progress made in our laboratory as well as in the field with a focus on anti-tumor immunity characterized in he- matologic malignancies in the following topics:（1） successful stories in anti-cancer immunotherapy;（2）tumor antigens in hematologic malignancies;（3.antigenological concepts and principles;（4. stimulation-responsive splicing model in generation of immunogenic tumor antigens;（5）significance of unconventional tumor antigens;（6）improvement of antigen epitope processing;（7）making of more ef- fective dendritic cells;（8）removal of immunosup- pressive regulatory T cells to unleash anti-tumor ira- munity and improve immunotherapy.

关键词： lymphoma leukemia tumor antigens new developments anti-tumor immune responses immunotherapy

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Journal of Wuhan university of Technology(Materials Science) 2009年第6期24卷 927-930页

作者：任平 department of Energy Sources and Environment Engineering Shanghai University of Electric Power

Spinel zinc ferrites ZnFe2O4. prepared by co-precipitation method using the zinc nitrate Zn（NO3.2·6H2O and ferric nitrate Fe（NO3.3.2H2O as the raw materials, were characterized by the thermo gravimetric analysis （TG） and differential scanning calorimeter （DSC）, X-ray diffraction （XRD） and scanning electron microscope （SEM）. The influence of synthesis conditions, such as Zn/Fe molar ratio, pH value, the sintering temperature and time, on the microstructures was detailedly investigated. The relationships between the microstructures and the synthesis conditions were discussed. The results show that the pure spinel zinc ferrites ZnFe2O4.are formed when the Zn/Fe molar ratio is 1.05∶2 at pH=8.5 or Zn/Fe molar ratio is 1∶2 at Ph=9-10, and the precursors are sintered at 1100 ℃ for 4.h. Especially no other phases are observed when the Zn/Fe molar ratio is 1∶2 at pH=10 and the precursor is sintered above 700 ℃ for 4.h. The higher sintering temperature and longer sintering time contribute to grain growth.

关键词： zinc ferrites ZnFe2O4 microstructures co-precipitation