检索结果-南通市图书馆

Study on the Corrosion Resistance of Multiphase TRIP Steels

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Journal of Iron and Steel Research International 2011年第S1期18卷 883-887页

作者： WANG Ji-jie 1,WU Di 2,LI Zhuang 1,GUO Xiang-min 1,HE Chun-lin 3,CAI Qing-kui 3 (1.school of Materials Science and engineering,shenyang university of Aeronautics and Astronautics,shenyang 110136,Liaoning,china 2.State Key Laboratory of Rolling and Automation,Northeastern university,shenyang 110004,china 3.Liaoning Province Key Laboratory for Advanced Materials,shenyang university,shenyang 110044,Liaoning,china) shenyang Univ Aeronaut & Astronaut Sch Mat Sci & Engn Shenyang 110136 Liaoning Peoples R China Northeastern Univ State Key Lab Rolling & Automat Shenyang 110004 Peoples R China shenyang Univ Liaoning Prov Key Lab Adv Mat Shenyang 110044 Liaoning Peoples R China

Multiphase TRIP (Transformation Induced Plasticity) steels are known to combine higher strength with higher *** this paper,the corrosion resistance of this steel has been has been investigated by accelerated corrosion tests,such as wet/dry cyclic corrosion and the weight loss in *** morphologies of their rust layers were observed by using scanning electron microscopy,and the corrosion performance of these steels was discussed by analyzing the protective *** results show that the corrosion rate of steel A is significantly greater than that of steels B and C in wet/dry cyclic corrosion and weight loss *** corrosion performance of conventional C-Mn-Si TRIP steel is deteriorated in both NaHSO 3 and 3.5 wt.% NaCl aqueous *** superior corrosion performance is exhibited for TRIP steel with low alloying contents due to its high thermodynamic *** enhancement of corrosion performance of TRIP steel is attributed to the additions of alloying elements,such as Al,Cu,Cr,Mo,Ni,*** alloying elements increase the compactness of rust layers,so electrochemical characteristic of TRIP steel is improved.

关键词： TRIP steel alloying element rust layer corrosion performance

IINFLUENCE OF HEAT TREATMENT TECHNOLOGY ON PROPERTY OF LOW COBALT Fe-Cr-Co PERMANENT MAGNETIC ALLOY

在线全文

学校读者我要写书评

暂无评论

Acta Metallurgica Sinica(English Letters) 1999年第5期12卷 911-916页

作者： Y.M.Wang and L.X.Ding Department of material, school of Mechanical engineering, shenyang university, shenyang 110044, china

The research is carried out through specification measurement of magnetic property, photo analysis of electronic microscope, metallographic analysis, micro hard and so on means. The initial researches have been done about the influence on material property by solid solution treatment, heat magnetic treatment and aging treatment technology of the low cobalt Fe Cr Co alloy. Therefore, better productive technologies have been found.

关键词： permanent magnetic alloy solid solution treatment aging treatment,cobalt.

Synthesis and Antitumor Activities of a New series of 4,5-Dihydro-l H-thiochromeno[4,3-d]pyrimidine Derivatives

在线全文

学校读者我要写书评

暂无评论

Synthesis and Antitumor Activities of a New series of 4,5-Di...

2011年全国药物化学学术会议——药物的源头创新

作者： De-Xiang GUO,Ya-Jing LIU,Ting LI,Nan WANG,Xin ZHAI,GONG Ping and Chun HU~* (school of pharmaceutical engineering,shenyang pharmaceutical university,shenyang 110016,china )

＜正＞The thiochroman-4-one ring moiety belongs to the privileged structure in modern medicinal chemistry,particularly in the discovery of new antitumor and antiangiogenic *** on（1） the analysis of the structure-act...

关键词：

温和气单孢菌YH311硫酸软骨素裂解酶的分离纯化与固定化

在线全文

cnki会议

学校读者我要写书评

暂无评论

生物工程学报 2004年第4期20卷 584-589页

作者：蔡苏兰阎浩林何汉洲沈阳药科大学制药工程学院沈阳110016

通过硫酸铵沉淀、QAE SephadexA5 0柱层析及SephadexG 1 5 0凝胶过滤等纯化步骤 ,对源自温和气单孢菌YH31 1的ChSase进行了分离纯化。结果表明 ,ChSase经上述纯化步骤后被纯化了 5 5倍 ,其最终纯度可达 95 %以上 ,比活为 31 86u mg。经... 详细信息

通过硫酸铵沉淀、QAE SephadexA5 0柱层析及SephadexG 1 5 0凝胶过滤等纯化步骤 ,对源自温和气单孢菌YH31 1的ChSase进行了分离纯化。结果表明 ,ChSase经上述纯化步骤后被纯化了 5 5倍 ,其最终纯度可达 95 %以上 ,比活为 31 86u mg。经SDS PAGE及IFE测定可知该酶的分子量约为 80kD ,等电点为 4 3～ 4 8。将纯化后的ChSase用海藻酸钠或纤维素固定化后 ,ChSase的热稳定性及贮存稳定性均可得到大幅度的提高 :固定化酶用 80℃水浴处理 1 2 0min或于 4℃冰箱放置 30d后仍可保留 5 0 %以上的相对活力 ;但固定化酶的收率较低 ,仅为 1 8 5 6 %和1 8 86 %。

关键词：硫酸软骨素裂解酶分离纯化固定化酶海藻酸钠纤维素

Synthesis Compensation Using Iterative Learning Control for Periodic Force Ripple of Permanent Magnet Linear Motor

在线全文

学校读者我要写书评

暂无评论

Synthesis Compensation Using Iterative Learning Control for ...

第11届国际电机与系统学术会议

作者： Ma Hang Yang Junyou school of Electrical engineering shenyang university of Technology shenyang 110178 P.R.china school of Electrical engineering Shenyang University of Technology Shenyang China

ISBN: (纸本)9787506292214

＜正＞A synthesis compensation approach of iterative learning control（ILC） is applied to minimization of periodic force ripples in a permanent magnet linear synchronous motor （PMLSM）.Based on position,speed and time axes,the synthesis approach enables powerfully to compensate periodic force ripples along three axes with feedforward approach in PMLSMs, meanwhile stochastic disturbances are restrained by feedback *** ILC scheme with variable step-size is adopted to improve convergent rate along *** ILC approaches converge into compensation tables along position,speed and time axes *** three ILC compensation schemes,an additional compensator combined with a conventional proportional-integral（PI） control is employed to generate a compensated reference current signal,which is added to the reference current from PI *** a consequence,the force pulsation is reduced *** proposed approach is evaluated by experiments,which validate its effectiveness.

关键词： Iterative Learning Control synthesis compensation periodic force ripples permanent magnet linear synchronous motor

Effects of resveratrol and its derivatives on lipopolysaccharide-induced microglial activation and their structure-activity relationships

在线全文

cnki会议

学校读者我要写书评

暂无评论

Effects of resveratrol and its derivatives on lipopolysaccha...

2008年全国抗衰老与老年痴呆学术会议

作者： Xue-Lian Meng~a Jing-Yu Yang~a Guo-Liang Chen~b Li-Hui Wang~a Li-Jia Zhang~a Shu Wang~a Jie Li~b Chun-Fu Wu~(a*) a:Department of Pharmacology,shenyang pharmaceutical university,shenyang 110016,P.R.china b:Department of pharmaceutical engineering,shenyang pharmaceutical university,shenyang 110016,P.R.china

AIM:In the present study,the inhibitory effects of 21 resveratrol derivatives on lipopolysaccharide(LPS)-induced Nitric oxide(NO)production in microglia and their structure-activity relationships were studied.

关键词： Resveratrol Microglia Nitric oxide iNOS TNF-α Structure-activity relationships

Clonidine,moxonidine,folic acid,and mecobalamin improve baroreflex function in stroke-prone,spontaneously hypertensive rats

在线全文

cnki会议

学校读者我要写书评

暂无评论

Acta Pharmacologica Sinica 2007年第10期28卷 1550-1558页

作者： Xiu-juan MA~(1,2),Fu-ming SHEN~1,Ai-jun LIU~1,Ke-yong SHI~(1,2),Ying-liang WU~2,Ding-feng SU~(1,2,3)~1 Department of Pharmacology Second Military Medical university,Shanghai 200433,china ~2 school of Pharmacy,shenyang Pharmaceu-tical university,shenyang 110016,china Department of Pharmacology Second Military Medical University Shanghai China school of Pharmacy Shenyang Pharmaceutical University Shenyang China

Aim:To investigate the effect of clonidine,moxonidine,folic acid,andmecobalamin on arterial baroreflex (ABR) function in stroke-prone spontane-ously hypertensive rats (SHR-SP) and the possible mechanisms ***:Eighty-one SHR-SP were divided into 7 *** groups weredesignated for the intragastric (ig) administration of clonidine (1.0 and 10.0μg/kg),moxonidine (0.1 and 1.0 mg/kg),folic acid (1.0 mg/kg),and mecobalamin(1.0 mg/kg).Three groups were for the intracerebroventricular (icv) injectionof clonidine (4 μg/4 μL),moxonidine (5 μg/4 μL),and mecobalamin (20 μg/4 μL).Blood pressure (BP) was recorded in the conscious state for 30 min andbaroreflex sensitivity (BRS) was determined respectively before and after ***:Clonidine and moxonidine significantly decreased BP,prolonged the heart period (HP),and increased BRS when administered as ei-ther ig or icv *** BP and HP were unchanged by ig folic acid ormecobalamin ***,BRS was significantly increased by ***:Clonidine,moxonidine,folic acid,and mecobalamin improvedimpaired ABR function in *** central mechanism was involved in thiseffect of either clonidine or *** improved ABR func-tion through the peripheral mechanism.

关键词： clonidine moxonidine folic acid mecobalamin arterial baroreflex stroke-prone spontaneously hypertensive rats

Effects of resveratrol,curcumin and their derivatives on the activation of microglia induced by LPS

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Effects of resveratrol,curcumin and their derivatives on the...

两岸三地药理学与临床药理学术会议

作者： YANG Jing-yu~1 MENG Xue-lian~1 ZHANG Li-jia~1 CHEN Guo-liang~2 WU Chun-fu~1 (1. Department of Pharmacology, shenyang pharmaceutical university, shenyang 110016, china 2.Department of pharmaceutical engineering, shenyang pharmaceutical university, shenyang 110016, china)

Objective To determine the inhibitory effects of 21 resveratrol derivatives and 3 natural curcumi- noids on lipopolysaccharide(LPS)-induced Nitric oxide(NO)and tumor necrosis factor-alpha(TNF-α) production in microglia and their structure-activity *** Cell viability was evaluated by the MTT reduction *** of nitrite(NO)in culture supernatant fluids was measured by the Griess *** nitroprusside(SNP)(2.5 mM)solution was used to determine the scavenging ac- tivities of these *** levels of TNF-αin the culture medium were measured by using an ELISA ***-quantitative RT-PCR analysis was used to determine the mRNA levels of inducible NOS(iNOS) and TNF-α.Results It was found,for the first time,that certain resveratrol derivatives that have 3,5- dimethoxyl groups in the A-ring,such as(E)-4-(3,5-dimethoxystyryl)phenol(pterostilbene,compound 2), or have substituted the B-ring of resveratrol with quinolyl,such as(E)-5-[2-(quinolin-4-yl)vinyl ] benzene- 1,3-diol(compound 18)and(E)-4-(3,5-dimethoxystyryl)quinoline(compound 19),strongly inhibited NO *** 2,18,and 19 reduced LPS-induced protein and mRNA expression of inducible NO synthase(iNOS),but did not display direct NO-scavenging activity up to 30μM in sodium nitroprusside (SNP)***,compounds 2,18,and 19 could also significantly inhibit the production of TNF-αby LPS-activated ***,we found the demethoxy derivatives of curcumin have more po- tent inhibition activity on NO and TNF-a releasing in *** In the present study we compared the activated-microglia inhibition effect of resvertrol,curcumin and their derivatives and pro- vided a glance of the structure-activity relationships of these compounds,the information is beneficial to de- sign new potent compounds which can provide better therapeutic implications for various neurodegenerative diseases.

关键词： resveratrol curcumin derivatives microglia NO TNF-a

山楂核中具有抗肿瘤活性化合物的分离(英文)

在线全文

cnki会议

学校读者我要写书评

暂无评论

中国天然药物 2013年第4期11卷 411-414页

作者：李玲芝彭缨牛超高品一黄肖霄毛新良宋少江沈阳药科大学中药学院沈阳110016 沈阳药科大学药学院沈阳110016 沈阳化工大学化学工程学院沈阳110142 苏州大学医学部药学院苏州215123 沈阳药科大学基于靶点的药物设计与研究教育部重点实验室沈阳110016

目的:对山楂核的化学成分及生物活性进行研究。方法:运用大孔吸附树脂D101,硅胶,ODS和制备高效液相色谱等方法分离化合物,通过多种波谱方法进行结构鉴定。此外,还对化合物进行了OPM2和RPMI-8226两组细胞株的细胞毒活性测试。结果:从山... 详细信息

目的:对山楂核的化学成分及生物活性进行研究。方法:运用大孔吸附树脂D101,硅胶,ODS和制备高效液相色谱等方法分离化合物,通过多种波谱方法进行结构鉴定。此外,还对化合物进行了OPM2和RPMI-8226两组细胞株的细胞毒活性测试。结果:从山楂核中得到4个化合物:(7S,8S)-4-[2-hydroxy-2-(4-hydroxy-3-methoxyphenyl)-1-(hydroxymethyl)ethoxy]-3,5-dimethoxybenzaldehyde(1),(+)-balanophonin(2),erythro-guaiacylglycerol-β-coniferylaldehydeether(3),buddlenolA(4)。结论:化合物1为一新降木脂素。化合物24为属内首次分离得到。活性测试结果表明化合物14的抗肿瘤活性不明显。

关键词：山楂降木脂素生物活性