检索结果-南通市图书馆

沈阳药科大学学报 2008年第S1期25卷 73-74页

作者： JI Yu-bin1,2,3,YANG Hai-fan1,YU Lei1,2,3,PANG lin-lin1,LI Hai-jiao1,LIU Guang-da1(1.Center of Research and Development on Life sciences and Environmental sciences,Harbin University of Commerce,Harbin 15.076,china 2.institute of Materia Medica and Postdoctoral Programme of Harbin University of Commerce,Harbin 15.076,china 3.Engineering Research Center of Natural Anticancer Drugs,Ministry of Education,Harbin 15.076,china)

Hepatocellular carcinoma(HCC)is one of the leading causes of cancer-related death in the *** carcinogenesis of HCC is multifactorial,multifunctional and *** suppressor gene therapy is one of the strategies,it is mainly used to make use of tumor suppressor gene groups which can inhibit the cell growth,to prevent the expression of oncogenes or to resume the function of *** so far,there is not a particular gene to be a main tumor suppressor gene in ***,it is necessary to study on the new anti-oncogenes to explain pathogenesis of liver cancer and seek for the newly effective target to carry on liver cancer gene ***(phosphatase and tensin homolog deleted on chromosome ten)was discovered as a tumor suppressor *** functions as a protein tyrosine phosphatase and as a lipid *** a lipid phosphatase,PTEN antagonizes PI3K/Akt signaling by dephosphorylating the D3 position of the inositol ring of phosphatidylinositol 3,4,5.trisphosphate(PIP3),to generate phosphatidylinositol-4,5.-biphosphate(PIP2).On the other hand,as a protein tyrosine phosphatase,PTEN can dephosphorylate itself,focal adhesion kinase(FAK)and the platelet derived growth factor receptor,involves in the migration,adhension of *** researches have been testified that there is a higher frequency of negative expression of PTEN protein in hepatocellular carcinoma,the negative correlation between expression of PTEN gene and differential grade,clinic stage of HCC indicated that in activation of PTEN gene maybe a late incidence in the development of hepatocellular carcinoma and may play an important role in the genesis and development of some hepatocellular ***6,a member of Krupple-like gene family,a ubiquitously expressed zinc finger transcription factor,has an important role in regulating cell growth and *** experiments have been proved that the genetic events of tumor suppressor gene mutation and loss of allele of K

关键词： HCC anti-oncogenes PTEN KLF6 p16

THE INVESTIGATION OF THE METAL DAMAGE AT THE CREEP BY THE METHOD OF ELECTRICAL RESISTANCE MEASURING

在线全文

学校读者我要写书评

暂无评论

Acta Mechanica Sinica 1991年第2期7卷 157-161页

作者： Lokochtchenko A.M.(institute of Mechanics,Moscow University,USSR) Visiting scholar(1988—1989)at South china University of Technology 1. institute of Mechanics Moscow University USSR

In this paper the method of damage measurement of metal structure at the creep is *** contrast to other methods,it allows the measurement of this damage to be carried out in the process of creep test without unloading and cooling of *** damage curves during creep are obtained as a result of test data processing by the suggested *** analysis of these curves leads to a conclusion that the material damage at repture is monotonically decreasing function of the applied *** conclusion is an experimental verification of the theoretical result,obtained earlier.

关键词： creep creep rupture structure damage electrical resistance metals copper kinetic equation

The force of oblique incident wave on the breakwater with a partially perforated wall

在线全文

学校读者我要写书评

暂无评论

Acta Oceanologica Sinica 2005年第4期24卷 125-134页

作者： LI Yucheng1*, LIU Hongjie2, DONG Guohai11. State Key Laboratory of Coastal and Offshore Engineering, Dalian University of Technology, Dalian 116023, china2. Zhejiang Provincial Plan Design & Research institute of Communications, Hangzhou 310006, china State Key Laboratory of Coastal and Offshore Engineering Dalian University of Technology Dalian 116023 China Zhejiang Provincial Plan Design Research Institute of Communications Hangzhou 310006 China

Wave forces induced by the interaction between the oblique incident wave and the breakwater with a partially perforated front wall isinvestigated. The fluid domain is divided into two sub-domains and the eigen-function expansion method is applied to expanding ve-locity potentials in each domain. In the eigen-expansion of the velocity potential, evanescent waves are included. Numerical results ofthe present model are compared with other theories and a good agreement can be found between them. Experimental data have beencompared with the present theoretical results. The effect of the traverse wall on wave forces has been discussed in detail. On the basisof the linear wave theory, it is shown that in the range of engineering practice, the incident angle of wave has small influence on waveforces on the unit length of perforated caisson.

关键词： partially perforated oblique incident wave wave force

理解中国城市劳动力市场——中国城市劳动力调查(第五轮)报告

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

劳动经济研究 2024年第1期12卷 3-27页

作者：中国城市劳动力调查课题组中国社会科学院人口与劳动经济研究所

为了深入理解中国城市劳动力市场,中国社会科学院人口与劳动经济研究所于2023年在全国8个代表性大城市开展了中国城市劳动力调查(第五轮)。调查共收集了381个居民委员会的9122份住户问卷和26145.个人问卷。调查数据包含城市本地住户和... 详细信息

为了深入理解中国城市劳动力市场,中国社会科学院人口与劳动经济研究所于2023年在全国8个代表性大城市开展了中国城市劳动力调查(第五轮)。调查共收集了381个居民委员会的9122份住户问卷和26145.个人问卷。调查数据包含城市本地住户和外来住户及其成员的就业、工作技能、教育培训、收入支出、社会保障等丰富信息,为在中国开展劳动经济学研究和公共政策分析提供了基础数据支撑。

关键词：住户调查劳动力市场就业

THERMODYNAMICS OF MELTING FOR METALS

在线全文

学校读者我要写书评

暂无评论

中国科学院大学学报 1995年第1期 41-51页

作者： Hong Yong-yan(institute of Solid State physics, Academia Sinica, Hefei 230026)Wu Feng-min (Zhejiang University of Technology, Hangzhou 310014)

ＴＨＥＲＭＯＤＹＮＡＭＩＣＳＯＦＭＥＬＴＩＮＧＦＯＲＭＥＴＡＬＳ￥ＨｏｎｇＹｏｎｇ－ｙａｎ（ＩｎｓｔｉｔｕｔｅｏｆＳｏｌｉｄＳｔａｔｅＰｈｙｓｉｃｓ，ＡｃａｄｅｍｉａＳｉｎｉｃａ，Ｈｅｆｅｉ２３００２６）ＷｕＦｅｎｇ... 详细信息

ＴＨＥＲＭＯＤＹＮＡＭＩＣＳＯＦＭＥＬＴＩＮＧＦＯＲＭＥＴＡＬＳ￥ＨｏｎｇＹｏｎｇ－ｙａｎ（ＩｎｓｔｉｔｕｔｅｏｆＳｏｌｉｄＳｔａｔｅＰｈｙｓｉｃｓ，ＡｃａｄｅｍｉａＳｉｎｉｃａ，Ｈｅｆｅｉ２３００２６）ＷｕＦｅｎｇ－ｍｉｎ（ＺｈｅｊｉａｎｇＵｎｉｖ...

关键词： free-electron model of melting latent heat of melting melting equation

On the Curing Theory and Scaling Study -The Polycondenzation of Aa-Bb Type

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Chemical Research in chinese Universities 1988年第3期 70-79页

作者： Tang Auchin, Li Zesheng, Sun Chiachung Tang Xinyi(institute of theoretical Chemistry and Chemistry Department, JilinUniversity, Changchun)

In this paper, a systematic way is proposed to treat the poly condenzation reaction with two species of monomers A and B having a-and b-functionalities, respectively. The polycondenzation reaction is considered as a whole to approach gel point which can be equivalently represented by three different kinds of forms. Furthermore, by means of a reasonable way without Stirling's approximation, the asymptopic form of the equilibrium number distribution characterized by A-B type near the gel point is obtained to reach a generalized scaling law.

关键词： Polycondenzation Stirling’s approximation scaling law.

Surface Reactivity in Tropical Highly Weathered Soils and Implications for Rational Soil Management

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Pedosphere 2004年第4期14卷 409-423页

作者： R.MOREAU J.PETARD Research institute for Development(IRD) 911 Avenue AgropolisBP 6450134394 Montpellier Cedex 5(France).Research Institute for Development(IRD)911 Avenue AgropolisBP 6450134394 Montpellier Cedex 5(France).

Highly weathered soils are distributed in the humid and wet-dry tropics, as well as in the humid subtropics. As a result of strong weathering, these soils are characterized by low activity clays, which develop variable surface charge and related specific properties. Surface reactions regarding base exchange and soil acidification, heavy metal sorption and mobility, and phosphorus sorption and availability of the tropical highly weathered soils are reviewed in this *** controlling surface reactivity towards cations and anions, including ion exchange and specific adsorption processes, are discussed with consideration on practical implications for rational management of these soils. Organic matter content and pH value are major basic factors that should be controlled through appropriate agricultural practices, in order to optimise favorable effects of colloid surface properties on soil fertility and environmental quality.

关键词： heavy metal highly weathered soils phosphorus tropical soil management variable charge minerals

Influence of supports on the oxidation of glucose on nano-gold catalysts

在线全文

学校读者我要写书评

暂无评论

Influence of supports on the oxidation of glucose on nano-go...

2011 World Congress on Engineering and Technology(CET 2011)

作者： Yue Tang 1 Mingqiao Zhu 2 Lin Huang 3 Yangyi Shen 4 Yangyang Yang 5.Department of Chemical and Biochemical Engineering Zhejiang University Hangzhou china 310027

Several kinds of nano-gold catalysts such as Au/TiO 2 ,Au/γ-Al 2 O 3 ,Au/SiO 2 and Au/MCM-41 were prepared by deposition precipitation method,using chloroauric acid as *** effects of supports on the catalytic performance for glucose oxidation were investigated and the catalysts were characterized by Transmission Electron Microscope （TEM）,X-Ray Diffraction （XRD）,Inductively Coupled Plasma-Atomic Emission Spectrometry （ICP-AES） and BET *** better catalyst is Au（1.0 wt%）/TiO 2 and the glucose conversion of approximately 100% in 1.5. was obtained.

关键词： glucose oxidation sodium gluconate gold catalyst

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

化学驱中动态界面张力行为的研究进展

石油学报 2001年第4期22卷 97-103页

作者：陈咏梅王涵慧俞稼镛中国科学院理化技术研究所北京100101

汇总了近年来强化采油动态界面张力研究进展的报道 ,阐述了驱油过程中的动态界面张力行为 ,总结了碱浓度、油相粘度、驱替液粘度对原油 /碱体系及原油 /碱 /聚合物体系动态界面张力的影响和表面活性剂、离子强度对原油 /碱 /表面活性剂... 详细信息

汇总了近年来强化采油动态界面张力研究进展的报道 ,阐述了驱油过程中的动态界面张力行为 ,总结了碱浓度、油相粘度、驱替液粘度对原油 /碱体系及原油 /碱 /聚合物体系动态界面张力的影响和表面活性剂、离子强度对原油 /碱 /表面活性剂体系及原油 /碱 /表面活性剂 /聚合物体系动态界面张力的影响。

关键词：动态界面张力强化采油表面活性剂化学驱油进展