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Chinese Experts Consensus on Biologic Therapy for Psoriasis

International Journal of Dermatology and Venereology 2020年第2期3卷 76-85页

作者： Chen Ai-Jun Gao Xing-Hua Gu Heng Gu Jun Hao Fei Jiang Xian Jin Hong-Zhong Kang Xiao-Jing Li Cheng-Xin Li Yu-Zhen Liu Xiao-Ming Shi Yu-Ling Sun Qing Wang Gang Yang Bin Zhang Jun-Ling Zhang Xi-Bao Zhang Xue-Jun Zhao Yi Zheng Min Chinese Society of Dermatology china Dermatologist Association Dermatology and Venereology Specialized Committee of Chinese Association of Integrative Medicine department of Dermatology The First Affiliated Hospital of Chongqing Medical UniversityChongqing 400016China department of Dermatology The First Hospital of China Medical UniversityShenyangLiaoning 110001China hospital for Skin Diseases(Institute of Dermatology) Chinese Academy of Medical SciencesNanjingJiangsu 210042China department of Dermatology Changhai HospitalThe Second Military Medical UniversityShanghai 200002China department of Dermatology The Third Affiliated Hospital of Chongqing Medical UniversityChongqing 401120China department of Dermatology West China Hospital of Sichuan UniversityChengduSichuan 610041China department of Dermatology Peking Union Medical College HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100730China department of Dermatology People’s Hospital of Xinjiang Uygur Autonomous RegionUrumqiXinjiang 830001China department of Dermatology The First Medical CenterPLA General HospitalBeijing 100853China department of Dermatology The Second Hospital of Harbin Medical University HarbinHeilongjiang 150086China department of Dermatology The University of Hong Kong-Shenzhen HospitalShenzhen 518053China department of Dermatology Shanghai Tenth People’s HospitalTongji University School of MedicineShanghai 200072China department of Dermatology Qilu HospitalShandong UniversityJinanShandong 250012China department of Dermatology Xijing HospitalThe Fourth Military Medical UniversityXi’anShaanxi 710032China Dermatology hospital of Southern medical university GuangzhouGuangdong 510091China department of Dermatology Tianjin Academy of Traditional Chinese Medicine Affiliated HospitalTianjin 300120China Institute of Dermatology Guangzhou Medical UniversityGuangzhouGuangdong 510095China department of Dermatology Huashan HospitalFudan UniversityShanghai 200040China department of Dermatology and Venereology Beijing Tsinghua Changgung HospitalSchool of Clinical MedicineTsinghua UniversityBeijing 102218China department of

Biologic drugs have been increasingly used in the treatment of psoriasis and are especially favorable for severe,recalcitrant,and special-type ***,appropriate,effective,and safe use of biologic drugs has drawn attention from *** this purpose,Chinese experts majoring in psoriasis analyzed domestic and international research data,summarized current clinical experiences,investigated features of Chinese patients with psoriasis,and finally formulated the present consensus,which provides detailed guidances to clinicians in terms of the principles and methods of the application of biologics,the efficacy and safety profile,patient screening and monitoring,main adverse events and corresponding solutions,and precautions for special patient populations.

关键词： psoriasis treatment biologics consensus

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上海市八所三级综合性医院2012—2015年经济运行分析

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解放军医院管理杂志 2018年第3期25卷 259-262页

作者：袁磊朱勃睿段光锋吴昊远赵娜段增杰田文华第二军医大学卫生勤务学系学员队上海200433 第二军医大学卫生勤务学系卫生事业管理学教研室上海200433 第二军医大学学员旅学员九队上海200433 第二军医大学研究生院上海200433 复旦大学社会发展与公共政策学院上海200433

目的了解医院经济运行的现状,发现存在的问题,并提出对策建议。方法对2012—2015年上海市8所三级综合性医院主要经济指标综合性描述分析。结果三级医院床位略有增长,资产增长速度较快;微观运行效率高,负荷持续加重;经济运行较为平稳,收... 详细信息

目的了解医院经济运行的现状,发现存在的问题,并提出对策建议。方法对2012—2015年上海市8所三级综合性医院主要经济指标综合性描述分析。结果三级医院床位略有增长,资产增长速度较快;微观运行效率高,负荷持续加重;经济运行较为平稳,收支结构仍待优化;医疗费用基本得到控制,药占比略有下降。结论控制三级医院规模,落实功能定位;加大政府投入,完善补偿机制;优化收支结构,控制医疗费用过快上涨;加强分工合作,推动分级诊疗。

关键词：三级医院经济运行上海公立医院改革

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Short-term and oncological outcomes of natural orifice specimen extraction surgery(NOSES)for colorectal cancer in china:a national database study of 5055 patients

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Science Bulletin 2022年第13期67卷 1331-1334,M0003页

作者： Xu Guan Xiyue Hu Zheng Jiang Ye Wei Donghui Sun Miao Wu Haitao Zhou Hongliang Yao Junmin Song Guiyu Wang Junhong Hu Mingyang Ren Qing Xu Jianchun Cai Jian Peng Dan Ma Yangchun Zheng Qingsi He Bo Jiang Zejun Wang Taiyuan Li Su Yan Luchuan Chen Tiegang Li Zhiguo Xiong Pan Chi Liang Kang Gang Yu Xiaodong Deng Hong Zhang Ming Xie Jianbao Wei Hongyan Gong Xuejun Sun Weidong Zang Yongmao Song Peng He Zhengqi Wen Chunxu Zhang Yusheng Wang Yinggang Chen Guangwei Xie Mingzhang Li Shaojun Yu Haiying Liu Min Pu Chuangang Fu Xishan Wang on behalf of china NOSES Alliance department of Colorectal surgery National Cancer Center/National Clinical Research Center for Cancer/Cancer HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100021China department of General surgery Zhongshan HospitalFudan UniversityShanghai 200032China department of Gastrointestinal and Anal surgery Jilin University First HospitalChangchun 130021China department of Gastrointestinal surgery The Second People’s Hospital of YibinYibin 644000China department of Gastrointestinal surgery The Second Xiangya HospitalCentral South UniversityChangsha 410011China department of Anorectal surgery First Affiliated HospitalZhengzhou UniversityZhengzhou 450052China department of Colorectal Cancer surgery The Second Affiliated Hospital of Harbin Medical UniversityHarbin 150081China department of Gastrointestinal surgery Affiliated Hospital of North Sichuan Medical CollegeNanchong 637000China department of Gastrointestinal surgery Renji HospitalShanghai JiaoTong University School of MedicineShanghai 200240China department of Gastrointestinal surgery Zhongshan Hospital of Xiamen UniversityXiamen 361004China department of General surgery Xiangya HospitalCentral South UniversityChangsha 410008China department of General surgery Xinqiao HospitalThird Military Medical UniversityChongqing 400037China department of Gastrointestinal surgery Sichuan Cancer HospitalChengdu 610041China department of General surgery Shandong University Qilu HospitalJinan 250012China department of Colorectal and Anal surgery Shanxi Cancer HospitalTaiyuan 030013China department of Gastrointestinal surgery The Affiliated Cancer Hospital of Guizhou Medical UniversityGuiyang 550008China department of General surgery The First Affiliated Hospital of Nanchang UniversityNanchang 330006China department of Gastrointestinal surgery Qinghai University Affiliated HospitalXining 810012China department of Gastrointestinal surgery Fujian Medical University Cancer HospitalFuzhou 350014China Depar

经自然腔道取标本手术(NOSES)通过无切口理念与常规手术器械的结合,表现出极佳的微创效果,并带给患者全新的就医感受.目前,尽管NOSES已广泛用于结直肠肿瘤治疗,大量研究也表明相比常规腹腔镜手术,NOSES具有恢复快、创伤小、疼痛轻等优势... 详细信息

经自然腔道取标本手术(NOSES)通过无切口理念与常规手术器械的结合,表现出极佳的微创效果,并带给患者全新的就医感受.目前,尽管NOSES已广泛用于结直肠肿瘤治疗,大量研究也表明相比常规腹腔镜手术,NOSES具有恢复快、创伤小、疼痛轻等优势,但绝大多数研究均为小样本、单中心回顾性研究.本研究旨在通过分析我国5055例结直肠肿瘤NOSES患者数据,进一步探讨NOSES的短期疗效与预后.研究对象中,经直肠NOSES占整体比例的90.3%,经阴道NOSES占9.7%.NOSES术后短期并发症发生率为14.1%,吻合口瘘发生率为4.9%,腹盆腔感染率为1.9%.患者3年总生存率为93.2%,无病生存率为82.2%,局部复发率为3.6%.研究结果提示NOSES具有较好的安全性与可行性,为其应用于结直肠肿瘤治疗提供了证据.

关键词：结直肠肿瘤肿瘤学并发症发生率无病生存率吻合口瘘回顾性研究总生存率经直肠

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Consensus on the Diagnosis and Treatment of Melasma in china (2021 Version)

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International Journal of Dermatology and Venereology 2021年第3期4卷 133-139页

作者： Pigmentary Disorder Group,Combination of Traditional and Western Medicine Dermatology Research Center for Vitiligo,Chinese Society of Dermatology Working Group on Pigmentary Disorders,china Dermatologist Association Tian-Wen Gao Hua Gu Li He Tie-Chi Lei Ming Li Tie-Nan Li Chun-Ying Li Tong Lin Kuan-Hou Mu Cai-Xia Tu Hai Wen Ji-Yuan Wu Ai-E Xu Jun-Ling Zhang Zhi-Zhong Zhen 不详 department of Dermatology Xijing HospitalThe Fourth Military Medical UniversityXi’anShanxi 710032China department of Dermatology The First Affiliated Hospital of Kunming Medical UniversityKunmingYunnan 650032China Renmin hospital of Wuhan university WuhanHubei 430000China department of Dermatology Zhongshan Hospital of Fudan UniversityShanghai 200000China department of Dermatology The 7th Municipal People’s Hospital in ShenyangShenyangLiaoning 110000China hospital for Skin Diseases(Institute of Dermatology) Chinese Academy of Medical Sciences and Peking Union Medical CollegeNanjingJiangsu 210000China department of Dermatology The First Affiliated Hospital of Xi’an Jiaotong UniversityXi’anShanxi 710032China department of Dermatology The Second Affiliated Hospital of Dalian Medical UniversityShenyangDalian 116000China department of Dermatology Changzheng Hospital of Navy Medical UniversityShanghai 200000China department of Dermatology The First Hospital of Wuhan CityWuhanHubei 430000China department of Dermatology The Third People’s Hospital of HangzhouHangzhouZhejiang 310000China The Affiliated hospital of Tianjin Academy of Traditional Chinese Medicine Tianjing 300000China department of Dermatology Huashan Hospital of Fudan UniversityShanghai 20000China

The pathogenesis of melasma is believed to be related to heredity,sun exposure,sex hormones,and other *** mechanisms underlying the development of melasma include increased melanin synthesis,vascular proliferation within the skin lesions,inflammation,and skin barrier *** diagnosis of melasma is mainly based on clinical manifestations and noninvasive *** with recent research progress in melasma,the present consensus comprehensively elaborates the etiology,pathogenesis,clinical manifestations,staging,classification,diagnosis,and treatment of melasma to improve the diagnostic and therapeutic skills of Chinese dermatologists.

关键词： diagnosis expert consensus melasma therapy

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脊神经后支相关性疼痛微创治疗技术中国疼痛科专家共识(2021版)

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中华疼痛学杂志 2021年第3期17卷 228-238页

作者：薛朝霞魏俊王祥瑞程志祥冯智英郑拥军张洪新张小梅白念岳刘伯龄贺纯静中华医学会疼痛学分会脊柱源性疼痛学组山西医科大学第一医院疼痛科太原市030001 赣南医学院第一附属医院疼痛科江西省赣州市341000 同济大学附属东方医院疼痛科上海市200120 南京医科大学第二附属医院疼痛科南京市210011 浙江大学医学院附属第一医院疼痛科杭州市310003 复旦大学附属华东医院疼痛科上海市200040 空军军医大学唐都医院疼痛介入科西安市710038 昆明医科大学第一附属医院疼痛科昆明市650032 中南大学附属湘雅医院疼痛科长沙市410078 厦门大学附属福州第二医院脊柱外科福州市350007 贵州省人民医院疼痛科贵阳市550002 不详

脊神经后支相关性疼痛疾病是临床常见病、多发病。本共识回顾并分析了脊神经后支解剖特点及相关疾病的临床表现、诊断、治疗,重点评价脊神经后支相关性疼痛微创治疗技术,包括注射治疗技术、针法松解技术、射频技术、化学损毁术、冷冻技... 详细信息

脊神经后支相关性疼痛疾病是临床常见病、多发病。本共识回顾并分析了脊神经后支解剖特点及相关疾病的临床表现、诊断、治疗,重点评价脊神经后支相关性疼痛微创治疗技术,包括注射治疗技术、针法松解技术、射频技术、化学损毁术、冷冻技术、内镜技术等。对各技术基本原理、适用范围及疗效进行了分析总结并提出了临床应用建议。

关键词：脊神经后支疼痛微创治疗技术注射疗法针刀松解疗法射频疗法内镜技术共识

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Diagnosis and Treatment of Acne Inversa/Hidradenitis Suppurativa in china: An Expert Consensus Statement (2021 Version)

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International Journal of Dermatology and Venereology 2021年第2期4卷 100-108页

作者： Hong Fang Xing-Hua Gao Song-Mei Geng Heng Gu Jun Gu Li He Xian Jiang Hong-Zhong Jin Qiang Ju Xiao-Jing Kang Wei Lai Cheng-Xin Li Hang Li Heng-Jin Li Shan-Shan Li Yu-Zhen Li Qing Sun Juan Tao Baoxi Wang Gang Wang Xin-Feng Wu Lei-Hong Xiang Hong-Fu Xie Hao-Xiang Xu Jin-Hua Xu Yan Yan Zhi-Zhong Zheng department of Dermatology The First Affiliated Hospital of Zhejiang UniversityHangzhouZhejiang 310003China department of Dermatology No.1 Hospital of China Medical UniversityShenyangLiaoning 110001China department of Dermatology The Second Affiliated Hospital of Xi’an Jiaotong UniversityXi’anShaanxi 710061China hospital for Skin Diseases(Institute of Dermatology) Chinese Academy of Medical Sciences and Peking Union Medical CollegeNanjingJiangsu 210042China department of Dermatology Shanghai Tenth People’s HospitalTongji University School of MedicineShanghai 200072China department of Dermatology First Affiliated Hospital of Kunming Medical UniversityKunmingYunnan 650032China department of Dermatology West China HospitalSichuan UniversityChengduSichuan 610041China department of Dermatology Peking Union Medical College HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100021China department of Dermatology Renji HospitalSchool of MedicineShanghai Jiaotong UniversityShanghai 200025China department of Dermatology People’s Hospital of Xinjiang Uygur Autonomous RegionUrumqiXinjiang 830001China department of Dermatology and Venereology The Third Affiliated HospitalSun Yat-sen UniversityGuangzhouGuangdong 510630China department of Dermatology First Medical Center of Chinese PLA General HospitalBeijing 100853China department of Dermatology and Venerology Peking University First HospitalBeijing 100034China department of Dermatology Hainan Hospital of PLA General HospitalSanyaHainan 572013China department of Dermatology and Venereology The First Hospital of Jilin UniversityChangchunJilin 130021China department of Dermatology Second Affiliated Hospital of Harbin Medical UniversityHarbinHeilongjiang 150086China department of Dermatology Qilu Hospital of Shandong UniversityJinanShandong 250012China department of Dermatology Affiliated Union HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhanHubei 430022China De

Acne inversa/hidradenitis suppurativa is a chronic,recurrent,inflammatory skin disease that affects the pilosebaceous units,causinfollicular *** etiology and pathogenesis of acne inversa/hidradenitis suppurativa involves internal and external factors such as genetic susceptibility,inflammation and immunity,microorganisms,obesity,and *** inversa/hidradenitis suppurativa is difficult to treat,and the current aim of treatment is to control the frequency and duration of disease flares and improve the quality of *** protocols for acne inversa/hidradenitis suppurativa should be selected based on the disease severity *** treatments include antibiotics,retinoids,biologics,immunosuppressive agents,and antiandrogen *** treatments include surgery and laser/light *** consensus aims to further standardize the diagnosis and treatment procedures of acne inversa/hidradenitis suppurativa in china to facilitate its diagnosis and treatment.

关键词： acne inversa consensus diagnosis hidradenitis suppurativa therapy

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血浆置换治疗儿童溶血尿毒综合征多中心流行病学调查

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中华实用儿科临床杂志 2018年第13期33卷 1022-1027页

作者：中国医师协会儿科医师分会血液净化专家委员会郑悦徐可雷晔飞冯仕品王墨郝志宏高岩李宇红周萍肖政辉赵凯妹夏正坤栾春丽刘雪梅赵丽君陆国平张育才陈朝英栾江威张建江刘翠华陈丽植赵成广吴玉斌姚勇曲强谢敏刘喜万俊丽焦佳石咏琪杨琴于力张瑶李颖杰许自川蒋新辉邵晓珊张思佳卢秀兰张岩马青山何旭史卓李倩孙书珍张洪霞潘艳艳仇三玲蔡小狄徐虹朱艳史婧奕耿海云祝高红戚畅贾莉敏刘俊梅厉洪江李广波蒋小云不详中国医科大学附属盛京医院小儿肾脏风湿免疫科沈阳110004 北京大学第一医院儿科 100034 郴州市第一人民医院儿科湖南郴州423000 成都市妇女儿童中心医院肾内科 610091 重庆医科大学附属儿童医院肾脏免疫科 400014 广州市第一人民医院儿科 510180 广州市妇女儿童医疗中心肾内科 510120 贵阳市儿童医院肾脏风湿科 550003 哈尔滨医科大学附属第二医院儿科 150086 湖南省儿童医院急救中心长沙410007 吉林大学白求恩第一医院儿童肾病科吉林130021 南京军区南京总医院儿科 210002 山东大学附属省立医院儿科肾脏风湿免疫科济南250021 山东大学齐鲁儿童医院肾内科济南250022 山西省儿童医院肾内科太原030013 复旦大学附属儿科医院重症医学科上海201102 上海市儿童医院重症医学科 200042 首都儿科研究所附属儿童医院肾内科 100020 武汉儿童医院肾内科 430016 郑州大学第一附属医院儿内科 450052 郑州大学附属儿童医院肾脏风湿科 450018 中山大学附属第一医院儿科广州510080

目的了解全国儿科血浆置换治疗溶血尿毒综合征（HUS）的现状，为进一步规范诊疗共识提供参考依据。方法中国医师协会儿科医师分会血液净化专家委员会讨论并制定调查表，以问卷调查的形式，收集22家单位2012年1月至2017年12月住院的146... 详细信息

目的了解全国儿科血浆置换治疗溶血尿毒综合征（HUS）的现状，为进一步规范诊疗共识提供参考依据。方法中国医师协会儿科医师分会血液净化专家委员会讨论并制定调查表，以问卷调查的形式，收集22家单位2012年1月至2017年12月住院的146例行血浆置换的HUS患儿的病历资料进行统计学分析。结果1．共收集数据146例，其中男91例，女55例；平均年龄5.68岁（2个月～18岁）；病因主要为感染（60例，41.1%），其次为补体缺陷（18例，12.3%）、药物（15例，10.3%）、风湿性疾病（9例，6.2%）及遗传代谢病（6例，4.1%）等。2.血液置换前患儿主要表现为少尿或无尿（101例），其次为意识障碍（45例）、高血压（58例）、消化道出血（42例）等症状，置换后明显缓解。3.血浆置换前实验室指标主要表现为血红蛋白[（68.26±18.17） g/L]、红细胞计数[（2.43±0.70） ×10^9/L]、血小板计数[（77.49±72.93） ×10^9/L]、补体C3[（0.70±0.26） g/L]、肾小球滤过率（GFR） [（26.98±17.16） mL/1.73 m2]下降，总胆红素[（44.33±42.07） μmol/L]、非结合胆红素[（30.78±26.68） μmol/L]、纤维蛋白降解产物（FDP）[（12.52±14.97） mg/L]、D-二聚体[（2 306.20±2 354.97） μg/L]、肌酐[（305.45±290.19） μmol/L]、24 h尿蛋白[（2.17±2.55） g/d]升高，置换后以上指标均显著好转[分别为（85.08±18.98） g/L、（2.80±0.98）×10^9/L、（183.80±131.95）×10^9/L、（0.85±0.25） g/L、（98.58±66.02） mL/1.73 m2、（19.71±33.24） μmol/L、（9.60±10.00） μmol/L、（7.33±9.81） mg/L、（1 322.05±1 595.23） μg/L、（139.28±163.75） μmol/L、（1.46±2.03） g/d]，差异均有统计学意义（均P〈0.05）。4.出现并发症5例，2例低血压休克，管路堵塞、血小板减少、贫血加重各1例。5.经治疗后好转130例（89%），死亡16例（11%）。结论血浆置换治疗儿童HUS在国内已较广泛开展，有效性和安全性已得到证实，其治疗时机有待循证医学进一步证实。

关键词：溶血尿毒综合征血浆置换儿童流行病学

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