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Influence of the redox state of QA on phycobilisome mobility in the cyanobacterium Synechocystis *** PCC 6803

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Influence of the redox state of QA on phycobilisome mobility...

Tripchlorolide protects against 1-methy1-4-phenyl-1,2,3.6-tetrahydropyridine（MPTP）-induced neurotoxicity in C57BL/6 mice

中国藻类学会第八次会员大会暨第十六次学术讨论会

作者： Liping Chen~1,Hualing Mi~2,Yungang Shen~2,Quanxi Wang~1,Weimin Ma~1 1 College of Life and environmental sciences,Shanghai normal {3.,Shanghai 20023., china 2 Institute of Plant Physiology and Ecology,Shanghai Institutes for Biological sciences, Chinese Academy of sciences,Shanghai 20003.,china

In a unicellular cyanobacterium,the mobile fraction of phycobilisome(PBS) was found to be maximum at a particular redox value of Q(i.e.,0.52).An upward or downward shift in the redox value leads to a decrease in this mobile fraction of ***, the regulatory effect of the redox state of Q on PBS mobility was found to be independent

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Tripchlorolide protects against 1-methy1-4-phenyl-1,2,3,6-te...

On the Partial Asymptotic Stability for Linear Time-Varying System

中国神经科学学会第四次会员代表大会暨第七届全国学术会议

作者： Zhen HONG,~1 Gang WANG,~1 Jing GU,~3.Jing PAN~1,Li BAT~1,Shi ZHANG~1,Sheng-Di CHEN~(1,2*) 1 Department of Neurology and Institute of Neurology,Ruijin Hospital affiliated to Shanghai Jiaotong university school of Medicine,Shanghai,200025 china 2 Institute of Health Science,Shanghai Institutes of Biological {3.(SIBS),Chinese Academy of {3.(CAS) & Shanghai Jiaotong university school of Medicine,Shanghai,200025 china 3.National Key Laboratory of Medical Neurobiology,Medical Center of Fudan university,Shanghai,20003. china.

＜正＞Many current theories of Parkinson’s disease（PD） suggest that inflammation is involved in the neurodegenerative ***（TW3.7）,a traditional Chinese herbal compound with anti-inflammatory and immunosuppressive properties,has been shown to protect and restore dopaminergic neurons against the neurotoxicity induced by 1-methyl- 4-phenylpyridinium ion in *** study was designed to investigate TW3.7’s effect in vivo in the PD model of 1- methyl-4-phenyl-1,2,3.6-tetrahydropyridine（MPTP） lesioned C57BL/6 *** the present study,the neurotoxin MPTP reduced the survival ratio of tyrosine hydroxylase-immunoreactive（TH-IR） neurons in the substantia nigra pars compacta and TH-IR fibers in striatum to 65%and 12%of the normal control,***,treatment with TW3.7 of 1μg/kg for 16 days once per day dramatically improved the survival rate of TH-IR neurons in the substantia nigra pars compacta and TH-IR fibers in striatum to 82%and 3.%of the control,meanwhile,significantly improved the level of dopamine in the substantia nigra and striatum to 157%and 191%of the vehicle-treated group,*** addition,the Rota-Rod performance of the animals treated with 0.5μg/kg or 1μg/kg TW3.7 were significantly improved for about 2 or 3.fold relative to vehicle-treated animals,*** data demonstrate a neuroprotective action of TW3.7 in vivo against MPTP toxicity,which has important implications for the treatment of PD.

关键词： Tripchlorolide neurotrophic Parkinson’s disease immunosuppressant 1-methyl-4-phenyl-1,2,3.6-tetrahydropyridine(MPTP) Tripterygium wilfordii Hook F.

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数学研究与评论 1989年第4期 546-545页

作者： Cao Qingjie&Xiang Kaiqi(QuFu normal university)

Consider system where y=（x1,…,xm）T, z=(xm+1,…,xn)T, A（t）,B（t）, C（t） and D（t） are the corresponding continuous matrices, （suppose that p=n-m>0）. Let Kp（t）=（B1T（t）,…,BpT（t）） (B1T（t）=BT（t）,BiT（t）=DT（t）Bi-1T（t）+Bi-1T（t）, i=2,…, p. Suppose that rank Kp（t）=h,let Li（t） is a transposed matrix from the columns at which the nonzero subeterminant of order h in Kp（t） was located, L2 satisfies that L1（t）L2T=0 and det L0（t）≠0. Let U=L（t）x, we can reduce system （1） to （2） as follows.

关键词： matrices suppose asymptotically columns nonzero ponding generalize exponent Russian hypothesis

Atmosphere-ocean interaction and teleconnection in the Northern Pacific during the cold season

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Acta Oceanologica Sinica 1992年第4期11卷 537-546页

作者： Jiang Quanrong and J. M. Wallace 1. Department of Atmospheric sciences, Nanjing university, Nanjing 210008, china2. Department of Atmospheric sciences, university of Washington 98195, U. S. A.

On the basis of the idea in our work (Jiang and Wallace, 1991) , the horizontal structure of SST pattern, the atmospheric response to SST change and the atmospheric forcing of the ocean in the Northern Pacific during the cold season are discussed. The results show that PNA pattern is the most prominent normal mode in the atmosphere-ocean interaction in the Northern Pacific during the cold season.

关键词： Atmosphere-ocean interaction Cold season Pacific Ocean (northern) Temperature, sea surface

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孤独症的认知障碍研究及其评述

心理科学进展 2010年第2期18卷 288-296页

作者：段蕾莫书亮华中师范大学心理学院湖北省人的发展与心理健康重点实验室武汉430079

执行功能紊乱理论(Theory of Executive Dysfunction)、弱的中央统合理论(Weak Central Coherence theory)和心理理论假说(The Theory of Mind Hypothesis)是解释孤独症认知障碍的三种重要理论。本文着重通过回顾以往的实验研究来探讨... 详细信息

执行功能紊乱理论(Theory of Executive Dysfunction)、弱的中央统合理论(Weak Central Coherence theory)和心理理论假说(The Theory of Mind Hypothesis)是解释孤独症认知障碍的三种重要理论。本文着重通过回顾以往的实验研究来探讨三种理论的产生、发展及前进的方向,以及三大理论之间的关系。三者可能从不同侧面诠释了孤独症认知障碍的机制,如何综合起来更好地揭示孤独症的认知障碍和病理机制,尚需深入和全面的研究。同时更多地考虑不同认知因素的交互影响以及研究的生态学效度,可能是进一步研究需要考虑的问题。

关键词：孤独症认知障碍心理理论执行功能弱的中央统合

Determination of Phosphorus by Inductively Coupled Plasma Atomic Emission Spectroscopy after Hydride Generation

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Chinese Chemical Letters 2000年第5期11卷 425-426页

作者： Zhe Feng FAN Li Min DU (Center of Analysis and Test. Shanxi normal university.Linfen 041004) Shanxi normal Univ Ctr Anal & Test Linfen 041004 Peoples R China

A continuous phosphine (PH3. generation was developed and applied to the sensitive detection of phosphorus by ICP-AES. Phosphate ion in aqueous solution was converted to phosphine by passing the sample solution through an incandescent copper silica-tube. Detection limit is 2 ng/mL. The relative standard deviation is 4.2% for 20 ng/mL. The method is rapid and simple with low contamination and high sensitivity.

关键词： hydride generation phosphate ICP-AES

Support vector machine for predicting protein interactions using domain scores

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Journal of Shanghai university(English Edition) 2009年第3期13卷 207-212页

作者：彭新俊王翼飞 Department of Mathematics College of SciencesShanghai University Department of Mathematics Shanghai Normal University

Protein-protein interactions play a crucial role in the cellular processsuch as metabolic pathways and immunological recognition. This paper presents a new domain score-based support vector machine （SVM） to infer protein interactions, which can be used not only to explore all possible domain interactions by the kernel method, but also to reflect the evolutionary conservation of domains in proteins by using the domain scores of proteins. The experimental result on the Saccharomyces cerevisiae dataset demonstrates that this approach can predict protein-protein interactions with higher performances compared to the existing approaches.

关键词： protein-protein interactions domains support vector machine (SVM) domain score

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青少年创造力的发展研究

心理科学 2009年第3期32卷 535-539页

作者：沃建中王烨晖刘彩梅林崇德西南大学重庆400715 北京师范大学发展心理研究所北京100875 北京师范大学认知神经科学与学习国家重点实验室北京100875 中央放手电视大学北京100031

创造性思维是创造力认知方向研究的一个热点,绝大多数研究者将发散思维作为测查的唯一指标。本研究将聚合思维也纳入测查指标,采用自编的《青少年创造性思维测验》,对我国青少年创造力的发展进行研究,结果表明:(1)青少年的创造力整体呈... 详细信息

创造性思维是创造力认知方向研究的一个热点,绝大多数研究者将发散思维作为测查的唯一指标。本研究将聚合思维也纳入测查指标,采用自编的《青少年创造性思维测验》,对我国青少年创造力的发展进行研究,结果表明:(1)青少年的创造力整体呈阶段性发展,在同一阶段内呈连续性,小学六年级到初一为发展的关键期。(2)女生创造力水平明显高于男生,主要表现在发散思维的流畅性和变通性子维度上。

关键词：青少年创造力发展

Enhanced sensitivity of hepatocellular carcinoma cells to chemotherapy with a Smac-armed oncolytic adenovirus

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Acta Pharmacologica Sinica 2007年第12期28卷 1996-2004页

作者： Qiu-wei PAN~(2,5),Su-yang ZHONG~(2,5),Bi-sheng LIU~2,Jin LIU~2,Rong CAI~2,Yi-gang WANG~2,Xin-yuan LIU~(2,3.4),Cheng QIAN~(2,4)~2 Xin Yuan Institute of Medicine and Biotechnology,Life Science College,Zhejiang Sci-Tech university Hangzhou 3.0018,china,~3.Instituteof Biochemistry and Cell Biology,Shanghai Institutes for Biological sciences,Chinese Academy of sciences,Shanghai 20003.,china Xin Yuan Institute of Medicine and Biotechnology Life Science CollegeZhejiang Sci-Tech UniversityHangzhou 310018China Institute of Biochemistry and Cell Biology Shanghai Institutes for Biological SciencesChinese Academy of SciencesShanghai 20003

Aim:The aim of the present study was to further improve the therapeutic effectsfor human hepatocellular carcinoma (HCC) and reduce the damage in normal cellsusing a novel chemo-gene-virotherapeutic ***:An oncolyticadenoviral vector (ZD55) similar to the typical oncolytic adenovirus ONYX-015,with a deletion of ElB-55K gene,was employed to express the second mitochon-dria-derived activator of caspases (Smac) protein by constructing a *** *** enhanced cytotoxicity of the combined treatment of ZD55-Smac with cisplatin or 5-fluorouracil (5-FU) was evaluated in several HCC ***,the negative effects on normal cells have been tested in humannormal liver cell lines L-02 and QSG-7701 cell lines by 3.(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay and apoptotic cell ***:According to our observation,ZD55-Smac is superior to ONYX-015 in sensitizingchemotherapy,ZD55-Smac used in conjunction with chemotherapy was found toexhibit obviously enhanced cytotoxicity in HCC cells,yet significantly abolishedthe negative toxicity in normal cells by utilizing the tumor selective replicationvector and reducing the ***:This chemo-gene-virotherapeutic(cisplatin or 5-FU+ZD55-Smac) strategy is superior to the conventional chemo-gene or chemo-viro approach.

关键词： oncolytic adenovirus inhibitor of apoptosis proteins second mitochondria-derived activator of caspases chemotherapy hepatocellular carcinoma