检索结果-南通市图书馆

CPU 86017, p-chlorobenzyltetrahydroberberine chloride, attenuates monocrotaline-induced pulmonary hypertension by suppressing endothelin pathway

在线全文

学校读者我要写书评

暂无评论

Acta Pharmacologica Sinica 2005年第11期26卷 1309-1316页

作者： Tian-tai ZHANG, Bing CUI, De-zai DAI~2, Wei SU research Division of Pharmacology, china Pharmaceutical university, Nanjing 210009, china researchDivisionofPharmacology ChinaPharmaceuticalUniversityNanjing210009China

Aim: To elucidate the involvement of the endothelin (ET) pathway in the pathogenesis of monocrotaline (MCT)-induced pulmonary arterial hypertension (PAH) and the therapeutic effect of CPU 86017 (p-chlorobenzyltetrahydroberberine chloride) in rats. Methods: Rats were injected with a single dose (60 mg/kg, sc) of MCT and given CPU 86017 (20,40, and 80 mg-kg-’-d-’, po) or saline for 28 d. The hemodynamics, mRNA expression, and vascular activity were evaluated. Results: Right ventricular systolic pressure and central venous pressures were elevated markedly in the PAH model and decreased by CPU 86017. In the PAH group, the endothelin-1 (ET-1) in serum and lungs was dramatically increased by 54% (79.9 pg/ mL, P3. (166.2 pg/mL, P3.% (P3.CPU 86017 groups, and preproET-1 mRNA abundance was also reduced notably in CPU 86017 80 mg-kg-’-d-1group vs the PAH group. The KCl-induced vasoconstrictions in the calcium-free medium decreased markedly in PAH group but recovered partially after CPU 86017 intervention. The constrictions in the presence of Ca2+was not improved by CPU 86017. The phenylephrine-induced vasoconstrictions in the calcium-free medium decreased markedly in PAH group but not recovered after CPU 86017 intervention. The constrictions in the presence of Ca2+completely re

关键词： pulmonary artery hypertension endothelin-1 nitric-oxide synthase reactive oxygen species monocrotaline CPU 86017

CONVERGENCE PROPERTIES OF DFP METHOD WITH MODIFIED QUASI-NEWTON EQUATIONS

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Journal of Systems Science & Complexity 2001年第3期14卷 293-305页

作者： TIAN Weiwen (Shanghai university, Shanghai 20043., china) PU Dingguo (Tongji university, Shanghai 2003.3. china) 上海大学上海 200436 同济大学上海 200333

Quasi-Newton (QN) equation plays a core role in contemporary nonlinear optimization. The traditional QN equation employs only the gradients, but ignores the function value information, which seems unreasonable. In this paper, we consider a class of DFP method with new QN equations which use both gradient and function value infor- mation and ask very little additional computation. We give the condition of convergence and superlinear convergence for these methods. We also prove that under some line search conditions the DFP method with new QN equations is convergeot and superlinearly con- vergent.

关键词： Quasi-Newton equation DFP updates superlinear convergence rate.

New concurrent digital signature scheme based on the computational Diffie-Hellman problem

在线全文

学校读者我要写书评

暂无评论

The Journal of china Universities of Posts and Telecommunications 2010年第6期17卷 89-94,100页

作者： QIN Wen,ZHOU Nan-run Department of Electronic Information Engineering,Nanchang university,Nanchang 3.003.,china [a] Department of Electronic Information Engineering Nanchang University Nanchang 330031 China

Based on strong designated verifiers signatures,a new fair concurrent signature scheme is proposed. Compared with the previous concurrent signature schemes,even if a keystone must be chosen by the initial signer,the matching signer will easily get the keystone through an extraction algorithm. Due to the property of strong designate verifying,the initial signer couldn＇t make use of the keystone prepared carefully to deceive the matching signer. Then the matching signer is able to participate actively the signature scheme. Besides,there aren＇t bilinear operations in the keystone algorithm to deliver the keystone efficiently. Therefore the efficiency of our signature scheme is also improved.

关键词： designated verifiers signature fairness concurrent signature information security

Density behaviors of Ge nanodots self-assembled by ion beam sputtering deposition

在线全文

学校读者我要写书评

暂无评论

Chinese Physics B 2013年第5期22卷 557-563页

作者：熊飞杨涛宋肇宁杨培志 research Institute of Engineering and Technology Yunnan University Key Laboratory of Education Ministry for Advance Technique and Preparation of Renewable Energy Materials Yunnan Normal University Department of Physics and Astronomy University of Toledo

Self-assembled Ge nanodots with areal number density up to 2.3.× 1010 cm-2 and aspect ratio larger than 0.12 are prepared by ion beam sputtering deposition. The dot density, a function of deposition rate and Ge coverage, is observed to be limited mainly by the transformation from two-dimensional precursors to three-dimensional islands, and to be associated with the adatom behaviors of attachment and detachment from the islands. An unusual increasing temperature dependence of nanodot density is also revealed when a high ion energy is employed in sputtering deposition, and is shown to be related to the breaking down of the superstrained wetting layer. This result is attributed to the interaction between energetic atoms and the growth surface, which mediates the island nucleation.

关键词： Ge nanodot self-organization ion beam sputtering deposition adatom behavior

在线全文

学校读者我要写书评

暂无评论

论中国马克思主义史学的史学观

上海大学学报(社会科学版) 2006年第3期13卷 5-17页

作者：瞿林东北京师范大学史学理论与史学史研究中心北京100875

中国马克思主义史学的史学观,是中国马克思主义史学的核心内容之一。它在学科体系、历史观和方法论、重视民族风格和史学遗产以及史家自身修养的境界等方面,都有突出的特点。加强中国马克思主义史学的史学观的研究,对理解中国马克思主... 详细信息

中国马克思主义史学的史学观,是中国马克思主义史学的核心内容之一。它在学科体系、历史观和方法论、重视民族风格和史学遗产以及史家自身修养的境界等方面,都有突出的特点。加强中国马克思主义史学的史学观的研究,对理解中国马克思主义史学的本质,推进中国马克思主义史学的发展,有重要的意义。

关键词：中国马克思主义史学史学观学科体系历史观和方法论民族风格史家修养

GPS IF data record and replay system based on FPGA

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

GPS IF data record and replay system based on FPGA

Decay of geometry for unimodal maps:The C^2 case

第三届中国卫星导航学术年会

作者： Kunlun Yan, Jiansheng Zheng, Tisheng Zhang, Di Zhang, Jinfeng Liu GNSS research center, Wuhan university, {3.

The non-reproducibility of the real signals makes on-site debugging more complex, and frequent on-site tests cost a lot, bringing a lot of trouble to the complete performance evaluation of the GPS receiver system. This thesis proposes a GPS IF data record and replay system based on FPGA and USB, describes the system design scheme, analyzes an optimizing design technique which guarantees the continuous, high-speed and stable record and replay of GPS data, and realizes a system in which IF data frequency point and data width can be flexibly adjusted. The tests show that the data record and replay format and results satisfy the design demands;the data format is of high flexibility, the high-speed data record and replay is continuous and stable which meets the performance evaluation demands of the receiver. The flexibility of data format and real-time replay not only enhance its practical value but also set the terms for the GPS and INS joint data record and replay system.

关键词： FPGA GPS IF record and playback USB2.0 high speed transfer

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

Chinese Science Bulletin 2009年第11期54卷 1859-1862页

作者： SHEN WeiXiao1,2 1 Department of Mathematics, university of Science and Technology of china, Hefei 23.026, china 2 Department of Mathematics, National university of Singapore, Singapore 117543. Singapore Department of Mathematics University of Science and Technology of China Hefei 230026 China Department of Mathematics National University of Singapore Singapore 117543 Singapore

We prove that a C2 unimodal interval map with critical order not greater than 2 has the decay of geometry property, by showing that all the cross-ratio estimates needed in the previous proof for the C3.case remain true.

关键词：衰变几何图案件几何性质比率估计证明

在线全文

学校读者我要写书评

暂无评论

油管接箍内壁车削加工中内表面圆度误差预测

上海交通大学学报 2009年第4期43卷 629-632页

作者：时轮马刘宝方戍刘茂生胡德金上海交通大学机械与动力工程学院上海200240 宝山钢铁股份有限公司钢管厂上海201900 上海消防研究所上海200438

通过分析油管接箍内壁车削加工中的残余夹紧变形,利用功的互等定理研究弹复效应对残余夹紧变形的影响,建立了仅与毛坯内、外径尺寸及车削加工后内壁径向尺寸相关的接箍内壁圆度误差预测模型.同时,针对预测算法,进行了接箍内壁车削加工实... 详细信息

通过分析油管接箍内壁车削加工中的残余夹紧变形,利用功的互等定理研究弹复效应对残余夹紧变形的影响,建立了仅与毛坯内、外径尺寸及车削加工后内壁径向尺寸相关的接箍内壁圆度误差预测模型.同时,针对预测算法,进行了接箍内壁车削加工实验,并将加工后的内壁圆度误差数据与理论预测数据进行比对.结果表明,所建立的模型仅与毛坯内、外径尺寸及车削加工后内壁径向尺寸有关.利用该模型只需在加工前静态测量夹紧力作用下工件内壁的变形量,即可预测加工后工件内壁的圆度误差,其实测内壁圆度误差与理论预测的相对误差不超过6%.

关键词：薄壁油管接箍残余夹紧变形圆度误差预测

Modeling golden section in plants

在线全文

学校读者我要写书评

暂无评论

Progress in Natural Science:Materials International 2009年第2期19卷 255-260页

作者： Lanling Zeng,Guozhao Wang Institute of Computer Graphic and Image Processing,Zhejiang university,Hangzhou 3.0027,china [a]Institute of Computer Graphic and Image Processing Zhejiang University Hangzhou 310027 China

Plants are complex structures,changing their shapes in response to environmental factors such as sunlight,water and neighboring plants. However,some mathematical rules can be found in their growth patterns,one of which is the golden section. The golden section can be observed in branching systems,phyllotaxis,flowers and seeds,and often the spiral arrangement of plant organs. In this study,tree,flower and fruit models have been generated by using the corresponding golden section characteristics,resulting in more natural patterns. Furthermore,the golden section can be found in the bifurcate angles of trees and lobed leaves,extending the golden section theory.

关键词： Golden section Plant morphology Plant modeling